Patent application number | Description | Published |
20100280066 | ACYLATED AMINO ACID AMIDYL PYRAZOLES AND RELATED COMPOUNDS - This invention is directed to acylated amino acid amidyl pyrazoles and related compounds of Formula I. The invention is also directed to a pharmaceutical formation comprising such compound or in a pharmaceutically acceptable salt form thereof. The invention is further directed to a method for inhibiting β-amyloid peptide release and/or synthesis, a method for inhibiting γ-secretase activity, and a method for treating neurological disorders associated with β-amyloid peptide production. The method comprises administering to a host a pharmaceutical formulation comprising an effective amount of a compound of Formula I. The compounds of Formula I are useful in the prevention and treatment of Alzheimer's disease. | 11-04-2010 |
20100331335 | Inhibitors of Jun N-Terminal Kinase - The present disclosure provides inhibitors of c-Jun N-terminal kinases (JNK) having a structure according to the following formula: | 12-30-2010 |
20110207716 | INHIBITORS OF POLO-LIKE KINASE - The present invention provides compounds having a structure according to Formula (I): | 08-25-2011 |
20110212942 | INHIBITORS OF POLO-LIKE KINASE - The present invention provides compounds having a structure according to Formula (I): | 09-01-2011 |
20120115848 | Inhibitors of Polo-Like Kinase - The present invention provides compounds having a structure according to Formula (I): | 05-10-2012 |
20130072494 | INHIBITORS OF JUN N-TERMINAL KINASE - The present disclosure provides inhibitors of c-Jun N-terminal kinases (JNK) having a structure according to the following formula: | 03-21-2013 |
20130231335 | INHIBITORS OF POLO-LIKE KINASE - The present invention provides compounds having a structure according to Formula (I): | 09-05-2013 |
20130331376 | INHIBITORS OF POLO-LIKE KINASE - The present invention provides compounds having a structure according to Formula (I): | 12-12-2013 |