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Jenison
Rick Lynn Jenison, Madison, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20120134522 | System and Method for Selective Enhancement Of Speech Signals - A system and method for selectively enhancing an audio signal to make sounds, particularly speech sounds, more distinguishable. The system and method are designed to divide an input auditory signal into a plurality of spectral channels having associated unenhanced signals and perform enhancement processing on a first subset of the spectral channels and not perform enhancement processing on a second subset of the spectral channels. The enhancement processing is performed by determining an output gain for at least the first subset of spectral channels based on a time-varying history of energy of the unenhanced signals associated with each channel in the first subset of the spectral channels and applying the output gain for each of the first subset of the spectral channels to the unenhanced signals to form enhanced signals associated with each of the first subset of the spectral channels. The system and method are then designed to combine the plurality of enhanced signals associated with each of the first subset of the spectral channels and the unenhanced signals associated with each of the second subset of the spectral channels to form a selectively enhanced output auditory signal. | 05-31-2012 |
Robert D. Jenison, Boulder, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20100304387 | METHODS AND COMPOSITIONS FOR SIGNAL ENHANCEMENT USING MULTIVALENT INTERACTIONS - Methods and materials are disclosed relating to an improved method for amplifying a signal in a diagnostic assay for an analyte, using an amplification polymer that multivalently binds to one or more non-analyte-specific binding site of the multivalent bridge conjugate, if present on the solid support. | 12-02-2010 |
| 20110039260 | METHODS AND COMPOSITIONS FOR AMPLIFYING A DETECTABLE SIGNAL - Methods and materials are disclosed relating to an improved method for amplifying a signal in a diagnostic assay for a nucleic acid, comprising the steps of providing an amplification polymer bound to a nucleic acid analyte, wherein the amplification polymer comprises a plurality of amine groups; binding amine groups on the amplification polymer with a detectable label complex; and reacting under high salt conditions an acetylating compound with amine groups not bound with a detectable label complex. | 02-17-2011 |
Robert Delmar Jenison, Boulder, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090215050 | SYSTEMS AND METHODS FOR POINT-OF-CARE AMPLIFICATION AND DETECTION OF POLYNUCLEOTIDES - Compositions and methods for amplifying and detecting solution-state polynucleotide targets in a single device are described. In one aspect, a method for a coupled isothermal amplification and detection process utilizes a coated solid support, including a solid substrate, a cationic layer, and a plurality of target-specific probes attached to the coated solid support. Polynucleotide targets in the sample are amplified by an isothermal amplification process involving in situ hybridization onto the coated solid support. The entire process can be carried out with a high degree of specificity under low salt conditions in less than one hour. Further aspects of the present invention include methods for coupled hybridization/detection of polynucleotide targets, coated silicon biosensors optimized for use with the coupled detection systems to provide visual detection of polynucleotide targets under visible light conditions, and kits for practicing the above described methods. | 08-27-2009 |
| 20100285479 | SYSTEMS AND METHODS FOR POINT-OF-CARE AMPLIFICATION AND DETECTION OF POLYNUCLEOTIDES - Composition and methods for amplifying and detecting solution-state polynucleotide targets in a single device are described. In one aspect, a method for a coupled isothermal amplification and detection process utilizes a coated solid support, including a solid substrate, a cationic layer, and a plurality of target-specific probes attached to the coated solid support. Polynucleotide targets in the sample are amplified by an isothermal amplification process involving in situ hybridization onto the coated solid support. The entire process can be carried out with a high degree of specificity under low salt conditions in less than one hour. Further aspects of the present invention include methods for coupled hybridization/detection of polynucleotide targets, coated silicon biosensors optimized for use with the coupled detection systems to provide visual detection of polynucleotide targets under visible light conditions, and kits for practicing in the above described methods. | 11-11-2010 |
Troy A. Jenison, Minneapolis, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20110196449 | ENABLEMENT AND/OR DISABLEMENT OF AN EXPOSURE MODE OF AN IMPLANTABLE MEDICAL DEVICE - This disclosure describes techniques for enabling and/or disabling an exposure operating mode using telemetry signals. A telemetry device may be configured to periodically transmit telemetry signals indicating presence of a source of a disruptive energy field in accordance with a communication protocol. An implantable medical device may be configured to receive the telemetry signals from the telemetry device and enter the exposure operating mode in response to receiving a first one of the telemetry signals indicating the presence of the source of the disruptive energy field. The implantable medical device may also exit the exposure operating mode in response to not receiving any of telemetry signals indicating the presence of the source of the disruptive energy field for a predetermined period of time. | 08-11-2011 |