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Jean-Philippe Rocher

Jean-Philippe Rocher, Plan-Les-Ouates CH

Patent application numberDescriptionPublished
20090082399Carbamate derivatives as positive allosteric modulators of metabotropic glutamate receptors - The present invention relates to new compounds which are Carbamate derivatives of formula I wherein X, B, P, Q5W, R03-26-2009
20090203737Pyrrole Derivatives as Positive Allosteric Modulators of Metabotropic Receptors - The present invention relates to new compounds which are Pyrrole derivatives of formula (I) wherein A, B, P, Q08-13-2009
20090215822Substituted Oxadiazole Derivatives as Positive Allosteric Modulators of Metabotropic Glutamate Receptors - The present invention relates to new compounds which are Oxadiazole derivatives of formula (I) wherein B, P, Q, W, R08-27-2009
20100004284Novel Heterocyclic Compounds as Positive Allosteric Modulators of Metabotropic Glutamate Receptors - The present invention relates to new compounds which are Heterocyclic derivatives of formula (I) wherein A, B, P, X, Y, Q, W, R01-07-2010
20100081690OXAZOLE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS - The present invention provides new compounds of formula I, wherein P, A, W, B, Q, R1 and R2 are defined as in formula I; invention compounds are positive allosteric modulators of metabotropic receptors—subtype 5 (“mGluR5”) which are useful for the treatment or prevention of central nervous system disorders such as for example: cognitive decline, both positive and negative symptoms in schizophrenia as well as other disorders in which the mGluR5 subtype of glutamate metabotropic receptor is involved.04-01-2010

Jean-Philippe Rocher, Geneva CH

Patent application numberDescriptionPublished
20090197897Novel Oxadiazole Derivatives and Their Use as Positive Allosteric Modulators of Metabotropic Glutamate Receptors - The present invention relates to new compounds which are Oxadiazole derivatives of formula (I) wherein B, P, Q, W, R08-06-2009

Jean-Philippe Rocher, Vetraz-Monthoux FR

Patent application numberDescriptionPublished
20090124625NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS - The present invention relates to novel compounds of formula (I) wherein W, n, X and W′ are defined in the description; invention compounds are modulators of metabotropic glutamate receptors—subtype 5 (“mGluR5”) which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.05-14-2009
20110112143ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS - The present invention relates to new compounds of formula (I) wherein A, B, P, Q, W, R05-12-2011

Patent applications by Jean-Philippe Rocher, Vetraz-Monthoux FR

Jean-Philippe Rocher, Vetraz-Mothoux FR

Patent application numberDescriptionPublished
200802874664-AMINO-2,3-DISUBSTITUTED THIENO [2,3,D]PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF - Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.11-20-2008