Patent application number | Description | Published |
20090023984 | DEVICE FOR INSUFFLATING THE INTERIOR OF A GASTRIC CAVITY OF A PATIENT - A method for laparoscopically preventing insufflation of the small bowel during gastric procedures includes applying an obstruction member at the pyloric sphincter to block the passage of gas from the gastric cavity into the small bowel and insufflating the gastric cavity. | 01-22-2009 |
20090023997 | DEVICE FOR INSUFFLATING THE INTERIOR OF A GASTRIC CAVITY OF A PATIENT - A method for endoscopically preventing insufflation of the small bowel during gastric procedures includes applying an obstruction member at the pyloric sphincter to block the passage of gas from the gastric cavity into the small bowel and insufflating the gastric cavity. | 01-22-2009 |
20090024077 | METHOD OF INSUFFLATING THE INTERIOR OF A GASTRIC CAVITY OF A PATIENT. - A method of insufflating the interior of a gastric cavity of a patient by accessing the gastric cavity of a patient, sealing the pyloric sphincter so as to prevent passage of fluids therethrough, and introducing a fluid within said gastric cavity proximal to the pyloric sphincter. | 01-22-2009 |
20090024144 | HYBRID ENDOSCOPIC/LAPAROSCOPIC DEVICE FOR FORMING SEROSA TO SEROSA PLICATIONS IN A GASTRIC CAVITY - A device for manipulating gastric tissue with an elongated hollow housing having distal and proximal ends. The housing contains at least one fastener. The fastener includes at least two anchors connected together by a flexible member. The flexible member has a knot disposed thereon. The knot is movable to draw together the anchors and lock them into position with respect to each other. The device also includes a penetrating member disposed at the distal end of the housing, and an actuator for deploying the fasteners distally through the housing and the penetrating member. | 01-22-2009 |
20090024148 | METHOD FOR FORMING PLICATIONS OF THE GASTRIC CAVITY - A method for forming plications of the gastric cavity is achieved by forming a tissue fold along a gastric wall of the gastric cavity and securing the tissue fold with a fastener, wherein the step of securing includes positioning at least one buttress between the tissue of the gastric wall and the fastener. | 01-22-2009 |
20090024163 | HYBRID ENDOSCOPIC/LAPAROSCOPIC METHOD FOR FORMING SEROSA TO SEROSA PLICATIONS IN A GASTRIC CAVITY - A method for treating obesity by reducing the volume and/or alter the functioning of the gastric cavity to limit food consumption and induce early satiety. The method includes accessing the cavity endoscopically to visualize the interior of the cavity. The peritoneal cavity is accessed through a small incision in the abdominal wall. Using endoscopic visualization, suture anchoring devices are introduced into the peritoneal cavity through the incision and deployed from the exterior surface through the gastric cavity wall. Suture from pairs of the anchoring devices is drawn through the gastric cavity wall and tightened outside of the cavity to form a serosa to serosa plication. Any number of plications may be formed in the cavity wall and the contacting tissue within a plication may be treated to promote healing and a more durable bond. | 01-22-2009 |
20090112232 | Method for Deploying A Device For Gastric Volume Reduction - A method for approximating tissue within a body including the step of providing a device having a handle, at least one actuator, an elongated hollow housing having a proximal end attached to the handle and a distal end extending therefrom, a first and second cartridge. Each the cartridge contains at least one fastener having at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The first cartridge being releasably connected to the distal end of hollow housing. The method also includes the step of inserting the first cartridge into a body and deploying each anchor into tissue in a spaced apart position. The method also involves moving the anchors adjacent one another by moving the suture in a proximal direction, and removing the first cartridge from the body and from the housing. The method then involves placing the second cartridge onto the housing thereby replacing the first cartridge with the second cartridge. | 04-30-2009 |
20090112234 | RELOADABLE LAPAROSCOPIC FASTENER DEPLOYING DEVICE FOR USE IN A GASTRIC VOLUME REDUCTION PROCEDURE - A reloadable device for deploying fasteners including a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device also includes a first cartridge containing at least one fastener releasably connectable to the distal end of hollow housing. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The device also includes a means for facilitating removal the first cartridge and replacing it with a second cartridge. | 04-30-2009 |
20090112304 | METHOD FOR PERFORMING A VASCULAR ANASTOMOSIS - A method for performing a coronary artery bypass graft procedure on a patient to connect a bypass vessel to a target vessel includes the steps of creating an opening in the patient that communicates with the thoracic cavity of the patient; providing a bypass vessel having a lumen and at least one free end; passing the free end of the bypass vessel from the thoracic cavity through the opening to a position outside the body of the patient; attaching a connector to the free end of bypass vessel while the free end of the bypass vessel is outside the body of the patient; passing the free end of the bypass vessel from the position outside the body of the patient through the opening and into the thoracic cavity; and connecting the free end of the bypass vessel to a target vessel with the connector. | 04-30-2009 |
20090118762 | Disposable cartridge for use in a gastric volume reduction procedure - A cartridge containing a fastener, wherein the cartridge releasably connected to a fastener deploying device. The cartridge has a housing which houses at least one tissue penetrating member. The penetrating member at least partially houses a fastener. The fastener has at least two rigid anchors connected together by a flaccid member. The cartridge further includes a means for removably attaching the cartridge to a deployment device. | 05-07-2009 |
20090192533 | METHODS AND DEVICES FOR DIAGNOSING PERFORMANCE OF A GASTRIC RESTRICTION SYSTEM - Methods and devices are provided for diagnosing performance of a gastric restriction system. In general, the methods and devices can enable patients, health care providers, and others to use pressure data as a feedback mechanism to monitor efficacy of an implantable restriction device and to identify, train, and/or prescribe treatment plan options. Pressure data monitoring can be used locally and/or remotely to monitor a restriction in a patient and compare gathered pressure data with a typical pressure of the restriction. Based on the results of the comparison, possible problems related to the patient and the restriction can be identified and diagnosed with possible cause(s) and solution(s). Notice of any detected possible problems, causes, and/or solutions can be provided to a user. | 07-30-2009 |
20090204131 | AUTOMATICALLY ADJUSTING BAND SYSTEM WITH MEMS PUMP - Devices and methods for forming a restriction in a patient are disclosed. In one exemplary embodiment, a restriction system is provided including an implantable restriction device, an implantable port in fluid communication with the implantable restriction device, and an implantable pump in fluid communication with the restriction device. In general, the implantable restriction device is adjustable and configured to form a restriction in a patient, and the implantable port is configured to receive fluid from a fluid source external to the patient. The implantable pump is a micro-electro-mechanical systems (MEMS) device effective to create pumping action to move fluid through the pump. | 08-13-2009 |
20090204132 | AUTOMATICALLY ADJUSTING BAND SYSTEM - Devices and methods for forming a restriction in a patient are disclosed. In one exemplary embodiment, a restriction system is provided including an implantable restriction device, an implantable port in fluid communication with the implantable restriction device, and an implantable pump in fluid communication with the restriction device. In general, the implantable restriction device is adjustable and configured to form a restriction in a patient, and the implantable port is configured to receive fluid from a fluid source external to the patient. The implantable pump has a plurality of actuators configured to change shape upon the application of energy thereto such that sequential activation of the plurality of actuators is effective to create pumping action to move fluid through the pump. | 08-13-2009 |
20090204141 | POWERING IMPLANTABLE RESTRICTION SYSTEMS USING KINETIC MOTION - Various powering devices are provided for transferring and/or generating energy from numerous sources to a communicating member implanted in a patient. The energy transferred to or generated by the communicating member can be used to provide power to an implantable restriction system configured to form a restriction in a pathway. | 08-13-2009 |
20090272783 | FASTENER AND FASTENER APPLIER HAVING SELECTIVE SUTURE ATTACHMENT - A surgical stapling device for deploying staples connected with suture to tissue includes a handle having a staple actuator mechanism, a tubular support shaft having a longitudinal axis and extending from the handle, and a staple cartridge mounted on the support shaft and connected to the staple actuator mechanism for applying one or more staples to the tissue. The cartridge has a cartridge housing adapted to receive a plurality of staples in a row for longitudinal movement therethrough and an anvil mounted on the housing. The cartridge further includes a mechanism for advancing the forwardmost staple in the row into engagement with the anvil, and a suture guide supporting a length of suture that extends in a loop for attachment to the staples as they are secured to the tissue. | 11-05-2009 |
20090272786 | SURGICAL STAPLING INSTRUMENT FOR APPLYING A LARGE STAPLE THROUGH A SMALL DELIVERY PORT AND A METHOD OF USING THE SURGICAL STAPLER TO SECURE A TISSUE FOLD - A low-profile surgical stapler enables a large-sized staple to be delivered into a body cavity through a small opening or port. The surgical stapler includes a handle having a trigger movably coupled to the handle. The surgical stapler also includes an elongated, tubular shaft extends distally from the handle. The tubular shaft includes a proximal end secured to the handle and a distal end in which a deployment opening is formed. A staple deploying assembly is disposed within an interior of the shaft for discharging staples from the deployment opening at the distal end of the shaft, the staple deploying assembly supporting a staple such that a longitudinal axis of the staple is aligned with a longitudinal axis of the shaft. The deployment opening is shaped and dimensioned to permit the deployment of the staples from within the shaft, out of the deployment opening and into adjacent tissue. | 11-05-2009 |
20090275957 | CLIP AND DELIVERY ASSEMBLY USED IN FORMING A TISSUE FOLD - A system for tissue apposition includes a delivery assembly having a tissue clip selectively secured thereto for the deployment and application of the tissue clip. The tissue clip is shaped and dimensioned for engaging spaced locations along a span of tissue and upon rotation thereof drawing the spaced locations together into apposition to thereby create a fold of tissue. | 11-05-2009 |
20090275961 | GASTRIC VOLUME REDUCTION USING ANTERIOR TO POSTERIOR WALL JUNCTIONS - A restriction system for joining anterior and posterior walls of a gastric cavity in the performance of the gastric reduction surgery includes a first restriction ring and a second restriction ring shaped and dimensioned for engagement with the first restriction ring for effectively decreasing the volume available within the gastric cavity. | 11-05-2009 |
20090275962 | TISSUE APPOSITION METHOD AND DEVICE INVOLVING SHEETS WITH INTEGRATED TENSIONING SYSTEM - A tensioning system for restricting the available volume of a gastric cavity includes a base material that is shaped and dimensioned for surgical attachment to surfaces on or within the body. Multiple tensioning members are incorporated into the base material, each of the tensioning members including a first end and a second end, wherein pulling upon the tensioning member will cause edges of the base material to be drawn together. The method for restricting the available volume of a gastric cavity includes securing edges of a tensioning system to the gastric cavity and drawing the edges of the tissue together to create a fold in the tissue. | 11-05-2009 |
20090275964 | METHOD OF ROLLING STOMACH TISSUE SO AS TO MAXIMIZE THE CONTACT SURFACE AREA OF A FOLD - A rolling instrument for rolling the outside surface of the stomach for reducing stomach volume in bariatric surgery includes an elongated tubular body that is sufficiently flexible to allow for access to the outside surface. The tubular body includes a proximal end and a distal end. The proximal end is shaped and dimensioned for use by the medical practitioner performing the medical procedure and includes a handle for manipulation of the rolling instrument. The distal end of the tubular body includes a mechanism allowing for gripping of the stomach in a manner permitting rolling thereof. A coiled retainer shaped and dimensioned is provided for application to the rolled portion of the stomach in a manner holding the rolled portion of the stomach in its rolled configuration. The coiled retainer includes a helically coiled body having a first end and a second end, the first end is pointed such that it may puncture tissue as the coiled body is rotated during its application to the stomach. | 11-05-2009 |
20090275975 | GASTRIC COIL MANIPULATOR - A gastric coil manipulator includes a longitudinally extending shaft having a distal end and a proximal end and a flexible element with a portion thereof extending beyond the distal end of the shaft for the creation of a resilient arc, wherein an actuator cable is secured to the flexible element for manipulation of the portion of the flexible element extending beyond the distal end of the shaft. | 11-05-2009 |
20090275977 | TISSUE CONVEYOR FOR USE IN GASTRIC REDUCTION SURGERY AND ASSOCIATED METHOD FOR USE - A tissue conveyor includes a conveyor body having a proximal end and a distal end. The proximal end includes a handle allowing for operator control of an end effector located at the distal end. The end effector includes a grasper assembly composed of a first jaw bar and a second jaw bar connected by a support base to define a cavity into which tissue is drawn. A first conveyor member is positioned upon the first jaw bar for movement along an internal surface of the first jaw bar and a second conveyor member is positioned upon the second jaw bar for movement along an internal surface of the second jaw bar. The method for creating a tissue fold includes positioning a tissue conveyor adjacent tissue, pushing the respective first jaw bar and the second jaw bar into the tissue in the area where a fold is desired, and pulling the first conveyor member and the second conveyor member proximally to draw the first and second conveyor members and tissue into a cavity defined by the first jaw bar and the second jaw bar to create a tissue fold. | 11-05-2009 |
20090275980 | METHOD AND APPARATUS FOR THE FORMATION OF TISSUE FOLDS - A suture anchoring device includes a fastener body composed of a tube and a spool is mounted within the tube for rotation relative to the tube. Suture material is wrapped about the spool such that pulling of the suture material causes rotation of the spool within the tube. A one-way locking mechanism allows the spool to rotate freely in a first direction and prevents rotation in an opposite direction. A method for creating a tissue fold includes deploying a first suture anchoring device within the tissue with suture material extending proximally from the first suture anchoring device, deploying a second suture anchoring device within the tissue with a distal portion of the suture material extending between the first suture anchoring device and a proximal portion of the suture material extending proximally from the second suture anchoring device, and applying tension to the suture material to draw portions of the tissue together to form a tissue fold. | 11-05-2009 |
20090276055 | METHOD FOR GASTRIC VOLUME REDUCTION SURGERY - A method for treating a patient includes creating at least one incision to gain access to an petitoneal cavity, performing a gastric volume reduction procedure and introducing a device to prevent gastric contents from interacting with at least a portion of the duodenum. | 11-05-2009 |
20100010511 | TISSUE APPOSITION CLIP APPLICATION DEVICES AND METHODS - Surgical instruments and methods for closing a gastrotomy. In various embodiments, the surgical instrument may comprise an overtube that supports a clip magazine therein that houses a plurality of tissue apposition clips in an orientation wherein the upper and lower clip arms thereof are releasably supported in an open orientation. Various embodiments are configured to operably accommodate one or more tissue grasping members for grasping the tissue. Other embodiments comprise clip dispensing adapters that may be affixed to the distal end of an endoscope. The various adapters are configured to support a tissue apposition clip such that the upper and lower clip arms thereof are initially supported in an open orientation relative to each other to enable grasped tissue to be drawn therein. Various tissue apposition clips are disclosed which may be used in connection with conventional tissue anchors and/or sutures. | 01-14-2010 |
20100023022 | RELOADABLE LAPAROSCOPIC FASTENER DEPLOYING DEVICE WITH DISPOSABLE CARTRIDGE USE IN A GASTRIC VOLUME REDUCTION PROCEDURE - A cartridge containing a fastener. The cartridge has an elongated sheath containing at least one tissue penetrating member. The penetrating member at least partially houses a fastener. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The cartridge further includes a means for deploying the anchors, wherein the means is movable within the sheath. | 01-28-2010 |
20100023024 | RELOADABLE LAPAROSCOPIC FASTENER DEPLOYING DEVICE WITH DISPOSABLE CARTRIDGE FOR USE IN A GASTRIC VOLUME REDUCTION PROCEDURE - A reloadable device for deploying fasteners. The device has a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The device also includes a means, adjacent the handle, for facilitating removal of the first cartridge from the handle and replacing it with a second cartridge. | 01-28-2010 |
20100023025 | Reloadable laparoscopic fastener deploying device with disposable cartridge for use in a gastric volume reduction procedure - A method of deploying fasteners within a body by providing a device having a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends, and a needle within the hollow housing. The device has a first cartridge containing at least one fastener releasably connectable to the distal end of the hollow housing. The fastener is at least partially housed within the needle and has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The method uses the steps of inserting the distal end of the hollow housing to a target site within a body, attaching tissue together within the body by deploying the fastener, and removing the first cartridge and replacing it with a second cartridge. | 01-28-2010 |
20100023026 | RELOADABLE LAPAROSCOPIC FASTENER DEPLOYING DEVICE WITH DISPOSABLE CARTRIDGE FOR USE IN A GASTRIC VOLUME REDUCTION PROCEDURE - A reloadable device for deploying fasteners. The device has a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device includes a first cartridge containing at least one fastener releasably connectable to the handle. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The first cartridge is removable from the handle. The device includes a second cartridge having at least one fastener releasably connectable to the handle after removal of the first cartridge. The second cartridge being insertable into the device from a proximal end thereof. | 01-28-2010 |
20100082046 | Device For Deploying A Fastener For Use in a Gastric Volume Reduction Procedure - A method and device for manipulating gastric tissue about a greater curvature of a stomach. The method includes the steps of creating at least one incision to gain access to the peritoneal cavity, and dissecting at least a portion of the greater omentum. Then the method includes accessing the exterior of the gastric tissue through the incision and folding at least a portion of the greater curvature of the stomach. The fold is constructed having serosa to serosa contact substantially along its entire length. The method further involves securing the fold with a flexible member wherein the flexible member comprises at least one tissue securing feature. | 04-01-2010 |
20100114125 | METHOD OF REMOTELY ADJUSTING A SATIATION AND SATIETY-INDUCING IMPLANTED DEVICE - An system, including an implant for placement within a hollow body organ. The system includes a member having an undeployed shape for delivery within a hollow body and one or more deployed shapes for implantation therein. The member has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The system includes an external means in communication with the member, the external means is remote from a patient, the external means comprises a means for remotely adjusting the shape of the member, and a means of powering the implant. | 05-06-2010 |
20100114141 | OPTIMIZING THE OPERATION OF AN INTRA-GASTRIC SATIETY CREATION DEVICE - A method for determining an optimum control parameter of a distension system for causing distension in a stomach. The method includes the step of providing an implantable distension system for causing distension in a stomach, the system including an adjustable distension device configured to form a distension in a stomach. The method also involves adjusting the distension device, and determining the value of a control parameter of the distension system. The method also involves repeating the steps of adjusting the distension device and determining the value of the control parameter until the control parameter is substantially convergent as a function of time. | 05-06-2010 |
20100114142 | POWERING IMPLANTABLE DISTENSION SYSTEMS USING INTERNAL ENERGY HARVESTING MEANS - An implant for placement within a hollow body organ. The implant includes a distension device having an undeployed shape for delivery within a hollow body and one or more deployed shapes for implantation therein. The distension device has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The implant also includes a powered means for changing the deployed shape of the member while implanted within the hollow body including an apparatus operable to convert energy produced by the patient into energy to power the implantable device. | 05-06-2010 |
20100114143 | WEARABLE ELEMENTS FOR INTRA-GASTRIC SATIETY CREATIONS SYSTEMS - A device, including an implant for placement within a hollow body organ. The implant includes a member having an undeployed shape for delivery within a hollow body and one or more deployed shapes for implantation therein. The member has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The implant includes a means for changing the deployed shape of the member while implanted within the hollow body. The device includes a wearable element configured to be worn by a patient, and has an external device coupled thereto and configured to send and/or receive a wireless signal to control the means for changing the deployed shape. | 05-06-2010 |
20100114144 | INTRA-GASTRIC SATIETY CREATION DEVICE WITH DATA HANDLING DEVICES AND METHODS - An implant for placement within a hollow body organ. The implant includes an implantable distension device having an undeployed shape for delivery within a hollow body and one or more deployed shapes for implantation therein. The implantable distension device has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The implant includes a powered means for changing the deployed shape of the implantable distension device while implanted within the hollow body. The implant also includes an implantable sensing device in communication with the implantable distension device and configured to sense a parameter related to the implantable distension device and to communicate the parameter to a filter, the filter transmits a selected portion of the parameter to a data storage device. | 05-06-2010 |
20100114145 | METHODS AND DEVICES FOR FIXING ANTENNA ORIENTATION IN AN INTRA-GASTRIC SATIETY CREATION SYSTEM - A device, including an implant for placement within a hollow body organ. The implant includes a member having an undeployed shape for delivery within a hollow body and one or more deployed shapes for implantation therein. The member has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The device includes a means for changing the deployed shape of the member while implanted within the hollow body. The means includes an antenna configured to wirelessly communicate with an external device. The external device is configured to communicate telemetrically with the member. The device further includes at least one means to limit rotational movement of the antenna relative at least one of the member and the external device. | 05-06-2010 |
20100114146 | METHODS AND DEVICES FOR PREDICTING INTRA-GASTRIC SATIETY AND SATIATION CREATION DEVICE SYSTEM PERFORMANCE - A method of affecting a weight loss treatment comprising the step of providing an implant for placement within a hollow body organ. The implant comprising a member having an undeployed shape for delivery within a hollow body and one or more deployed shapes for implantation therein. The member has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The implant also includes a means for changing the deployed shape of the member while implanted within the hollow body. The method further includes the steps of implanting the implant within a patient, implanting a data gathering device within the patient, collecting physiological data of a patient relating to the implant, and comparing the data to a fixed value and changing the shape of the member. | 05-06-2010 |
20100114148 | DEVICES AND METHODS FOR ADJUSTING A SATIATION AND SATIETY-INDUCING IMPLANTED DEVICE - An implant for placement within a hollow body organ having a member with an undeployed shape, for delivery within a hollow body, and one or more deployed shapes, for implantation therein. The member has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The implant also includes a means for changing the deployed shape of the member while implanted within the hollow body. | 05-06-2010 |
20100114149 | AUTOMATICALLY ADJUSTING INTRA-GASTRIC SATIATION AND SATIETY CREATION DEVICE - An implant for placement within a hollow body organ, the implant includes a distension device having an undeployed shape for delivery within a hollow body and one or more deployed shapes for implantation therein. The device has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The implant further includes an implantable pump in fluid communication with the distension device and having a plurality of actuators configured to change the shape of the distension device upon the application of energy thereto such that sequential activation of the plurality of actuators is effective to create pumping action to move fluid through the pump. | 05-06-2010 |
20100185225 | GUI FOR AN IMPLANTABLE DISTENSION DEVICE AND A DATA LOGGER - A device, including a display and an implant for placement within a hollow body organ, the device includes a member having an undeployed shape for delivery within a hollow body and one or more deployed shapes for implantation therein. The member having sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The device includes a means for changing the deployed shape of the member while implanted within the hollow body. The device also includes a wireless device, external to a body of a patient, for controlling the means and for changing the deployed shape of the member while implanted within the hollow body. | 07-22-2010 |
20100187283 | Method For Feeding Staples In a Low Profile Surgical Stapler - A method for feeding a fastener including the step of providing a device having a housing, at least one fastener within the housing, wherein the fastener is disposed within the housing in a first plane, an elongated actuator disposed within the housing, the actuator comprising a shaft substantially parallel to a longitudinal axis of the housing and rigidly spaced from the fastener in a second plane the actuator comprising at least one radially extending advancer disposed along a length thereof. The method further includes the step of rotating the actuator so to engage the fastener, and longitudinally moving the actuator to advance the fastener. | 07-29-2010 |
20100187284 | Apparatus For Feeding Staples In a Low Profile Surgical Stapler - A mechanism for feeding a fastener including a housing having a longitudinal axis and at least one fastener within the housing. The fastener has a crown and at least two legs extending therefrom. The fastener is disposed within the housing in a first plane parallel to the longitudinal axis. The mechanism includes an elongated actuator disposed within the housing. The actuator has a shaft substantially parallel to the longitudinal axis of the mechanism and rigidly spaced from the fastener in a second plane. The actuator has at least one radially extending advancer disposed along a length thereof, and a mechanism for rotating the actuator so that the advancer engages the fastener. | 07-29-2010 |
20100187285 | SURGICAL STAPLER FOR APPLYING A LARGE STAPLE THOUGH A SMALL DELIVERY PORT AND A METHOD OF USING THE STAPLER TO SECURE A TISSUE FOLD - A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains a plurality of surgical fasteners. The surgical fasteners have a base, and two legs extending away from the base, wherein the legs have distal end segments. The fastener has a first shape wherein the distal end segments bend towards each other so that they are adjacent and form the fastener into a first loop. The fastener has a second shape wherein the distal end segments are spaced apart from each other along substantially an entire length thereof. The fastener also has a third shape wherein the distal end segments bend towards each other in so that they are adjacent and form the fastener into a second loop wherein the second loop having a width greater than a width of the first loop. The applier includes a means for forming the fastener into the second and third shapes. | 07-29-2010 |
20100191255 | Method for Applying A Surgical Staple - A method of deploying a surgical fastener including the step of introducing the fastener into a body of a patient while the fastener is in a first shape having a first loop with a back span and an original size and shape. The method involves moving the end segments of the fastener in a first manner away from each other while maintaining the fastener in a closed loop. The method also involves moving the end segments of the fastener in a second manner away from each other to open the loop. The method further involves forming the fastener into a second loop having a width greater than the width of the first loop. | 07-29-2010 |
20100191258 | SURGICAL STAPLER FOR APPLYING A LARGE STAPLE THROUGH A SMALL DELIVERY PORT AND A METHOD OF USING THE STAPLER TO SECURE A TISSUE FOLD - A method of deploying a surgical fastener using the steps of introducing a fastener into a body of a patient while the fastener is in a first shape forming a first loop. Moving end segments of the fastener away from each other substantially along an entire length thereof. And forming the fastener into a second loop having a width greater than a width of the first loop. | 07-29-2010 |
20100191262 | SURGICAL STAPLER FOR APPLYING A LARGE STAPLE THROUGH SMALL DELIVERY PORT AND A METHOD OF USING THE STAPLER TO SECURE A TISSUE FOLD - A surgical fastener having a base, and two legs extending away from the base. The legs have distal end segments. The fastener has a first shape wherein the distal end segments bend towards each other in so that they are adjacent and form the fastener into a first loop. The fastener has a second shape wherein the distal end segments are spaced apart from each other along substantially an entire length thereof. The fastener has a third shape wherein the distal end segments bend towards each other so that they are adjacent and form the fastener into a second loop, wherein the second loop has a width greater than a width of the first loop. | 07-29-2010 |
20100191282 | Surgical Stapler For Applying A Large Staple Through A Small Delivery Port And A Method of Using The Stapler To Secure A Tissue Fold - A method of deploying a surgical fastener into a patient by introducing the fastener into a body of a patient while the fastener is in a first shape having a first loop with a back span and an original size and shape. The method then involves moving end segments of the fastener away from each other substantially along an entire length thereof while keeping the back span in substantially its original size and shape. The method then involves forming the fastener into a second loop having a width greater than a width of the first loop. | 07-29-2010 |
20110060308 | METHODS AND IMPLANTS FOR INDUCING SATIETY IN THE TREATMENT OF OBESITY - A method for inducing satiety using the steps of inserting an elongated device into a patient through a natural orifice and into a stomach of the patient, placing a distal end of the elongated device adjacent a treatment site within the stomach, and delivering at least one space occupying member through the elongated device adjacent the treatment site and implanting the at least one space occupying member between the submucosal and muscularis layers at the target site. | 03-10-2011 |
20110060358 | METHODS AND IMPLANTS FOR INDUCING SATIETY IN THE TREATMENT OF OBESITY - A device for inducing satiety including an elongated device for insertion through a natural orifice and into a stomach of the patient. The distal end of the device includes a means for occupying space between the submucosal and muscularis layers adjacent a pyloric sphincter. The means has a collapsed state for delivery to a target site and an expanded state for implantation thereof. | 03-10-2011 |
20110082471 | Reloadable Laparoscopic Fastener Deploying Device - A device for deploying fasteners including a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The device also includes an elongated pusher movable through the hollow housing from the proximal to the distal end to deploy the fasteners. The device further includes a deforming member for deforming the pusher at a proximal end thereof while advancing the pusher to the distal end of the housing. | 04-07-2011 |
20110082472 | Method For Deploying Fasteners For Use In a Gastric Volume Reduction Procedure - A method for deploying fasteners including the steps of providing a device having a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle and an elongated pusher movable through the hollow housing from the distal to the proximal end for deploying the fastener from the distal end. The method includes increasing the stiffness of the pusher at a distal end thereof and advancing the pusher through the elongated housing to deploy the fasteners. | 04-07-2011 |
20110130772 | Device For Deploying A Fastener For Use In A Gastric Volume Reduction Prodecure - A method and device for manipulating gastric tissue about a greater curvature of a stomach. The method includes the steps of creating at least one incision to gain access to the peritoneal cavity, and dissecting at least a portion of the greater omentum. Then the method includes accessing the exterior of the gastric tissue through the incision and folding at least a portion of the greater curvature of the stomach. The fold is constructed having serosa to serosa contact substantially along its entire length. The method further involves securing the fold with a flexible member wherein the flexible member comprises at least one tissue securing feature. | 06-02-2011 |
20110251609 | ELECTROSURGICAL CUTTING AND SEALING INSTRUMENTS WITH JAWS HAVING A PARALLEL CLOSURE MOTION - Various embodiments are directed to a surgical instrument comprising, a shaft, and an end effector. The shaft may be coupled to the handle and may extend distally along a longitudinal axis. The end effector may be positioned at a distal end of the shaft and may comprise first and second jaw members and a reciprocating member. The first and second jaw members may define first and second longitudinal slots. The reciprocating member may be translatable distally and proximally parallel to the longitudinal axis and through the first and second longitudinal slots. A distal portion of the reciprocating member may define a blade. The end effector may additionally comprise a first push rod member having a distally directed end pivotably coupled to the first jaw member and a proximally directed end pivotably coupled to the shaft at a first pivot point as well as a first linkage member having a distally directed end pivotably coupled to the first jaw member and a proximally directed end pivotably coupled to a second pivot point. In this way, distal motion of the reciprocating member may exert a force on the first and second jaw members causing the first and second jaw members to translate towards one another in a substantially parallel motion. | 10-13-2011 |
20110251613 | ELECTROSURGICAL CUTTING AND SEALING INSTRUMENTS WITH CAM-ACTUATED JAWS - Various embodiments are directed to a surgical instrument comprising, a shaft, and an end effector. The shaft may be coupled to the handle and may extend distally along an longitudinal axis. The end effector may be positioned at a distal end of the shaft and may comprise first and second jaw members, a reciprocating member, a shuttle and at least one cam pin. The first and second jaw members may define first and second longitudinal slots and first and second cam slots and may be pivotable towards one another about a pivot point. The reciprocating member may be translatable distally and proximally parallel to the longitudinal axis and through the first and second longitudinal slots. A distal portion of the reciprocating member may define a blade. The shuttle may be translatable distally and proximally parallel to the longitudinal axis. The cam pin may be coupled to the shuttle and positioned within the first cam slot and the second cam slots. | 10-13-2011 |
20110263490 | Diagnostic Methods and Combination Therapies Involving MC4R - Methods and therapeutics are provided for treating metabolic disorders by activation of melanocortin signaling pathways. Generally, the methods and therapeutics can induce activation of melanocortin receptor signaling to increase energy expenditure and induce weight loss. In one embodiment, a method for performing a diagnostic procedure can be chosen, energy expenditure then assess in light of the diagnostic procedure and a definitive procedure(s) can be selected dependent on the outcome of the energy assessment. In another embodiment, a diagnostic procedure can be chosen to activate melanocortin receptor pathways, energy expenditure can be assessed and a definitive procedure(s) can be chosen that selectively and optimally activate melanocortin receptor pathways. | 10-27-2011 |
20110270360 | METHODS AND DEVICES FOR ACTIVATING BROWN APIDOSE TISSUE USING ELECTRICAL ENERGY - Methods and devices are provided for activating brown adipose tissue (BAT). Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss. In one embodiment, a medical device is provided that activates BAT by electrically stimulating nerves that activate the BAT and/or electrically stimulating brown adipocytes directly, thereby increasing thermogenesis in the BAT and inducing weight loss through energy expenditure. | 11-03-2011 |
20110282339 | SURGICAL INSTRUMENTS AND END EFFECTORS THEREFOR - Various forms of surgical instruments are disclosed. In various embodiments, an end effector having operable and closable jaws is attached to a distal end of an elongate shaft such that portions of the jaws are axially offset from the elongate shaft. Other jaw embodiments are coupled to an actuation arrangement that permits portions of the jaws to be moved out of axial alignment with the elongate shaft. Other jaw embodiments are configured to facilitate tissue dissection. Electrosurgical instruments are also disclosed. One embodiment employs a flexible electrode that is conformable to tissue. | 11-17-2011 |
20110295054 | Method of Filling an Intraluminal Reservoir with a Therapeutic Substance - Methods described herein involve introducing a nasogastric tube into a patient, connecting the nasogastric tube with a reservoir, anchoring the nasogastric tube with the nasal cavity, and introducing a substance into the reservoir through the nasogastric tube. | 12-01-2011 |
20110295055 | Methods and Devices For The Rerouting Of Chyme To Induct Intestinal Brake - Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may comprise one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure. | 12-01-2011 |
20110295056 | SYSTEMS AND METHODS FOR GASTRIC VOLUME REGULATION - Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated. | 12-01-2011 |
20110295057 | SYSTEMS AND METHODS FOR GASTRIC VOLUME REGULATION - Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated. | 12-01-2011 |
20110295151 | Enteroendocrine Manipulation for Metabolic Effect - L-cells may be introduced in the gastrointestinal tract. L-cells are used in the digestive process to produce a more efficient and lasting means of regulating feelings of satiation in a patient. Desired metabolic effects may be achieved by manipulating L-cells via delivery sites, frequency of delivery, or type of biological substance delivered. | 12-01-2011 |
20110295178 | Intestinal Brake Inducing Intraluminal Therapeutic Substance Eluting Devices and Methods - Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices may be accomplished via stabilized implantable systems and ingestible pills. In one aspect, a method of inducing satiety includes implanting an implant within a lumen of a gastrointestinal tract and retaining a portion of chyme that flows by the implant within a body of the implant. The method further involves re-releasing the retained chyme from the implant into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis. | 12-01-2011 |
20110295179 | METHODS AND DEVICES FOR REGULATING THE ACTIVATION OF GHRELIN HORMONES WITHIN A STOMACH - Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance. | 12-01-2011 |
20110295180 | INTESTINAL BRAKE INDUCING INTRALUMINAL THERAPEUTIC SUBSTANCE ELUTING DEVICES AND METHODS - Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient. | 12-01-2011 |
20110295185 | Intestinal Brake Inducing Intraluminal Therapeutic Substance Eluting Devices and Methods - Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract. | 12-01-2011 |
20110295286 | METHODS AND DEVICES FOR REGULATING THE ACTIVATION OF GHRELIN HORMONES WITHIN A STOMACH - Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance. | 12-01-2011 |
20110295337 | Systems and Methods For Regulating Metabolic Hormone Producing Tissue - A method for regulating hormone production comprises placing at least one electrode in a gastrointestinal tract of a patient and recording an electrical signal during a preselected event produced by the gastrointestinal tract. The method further involves the steps of storing the electrical signal, and playing back the electrical signal by activating the electrode during the absence of the preselected event. | 12-01-2011 |
20110306964 | ELECTROSURGICAL INSTRUMENT EMPLOYING PRESSURE-VARIATION ELECTRODES - A surgical instrument can comprise a handle, a first conductor, a second conductor, and an end effector. The end effector can comprise a first jaw, a second jaw, wherein the first jaw is movable relative to the second jaw in order to capture tissue intermediate the first jaw and the second jaw, a first electrode electrically coupled with the first conductor, and a second electrode electrically coupled with the second conductor, wherein the second electrode is comprised of a material configured to have a first electrical resistance when a first pressure is applied to the material, and wherein the material is configured to have a second electrical resistance when a second pressure is applied to the material. In various circumstances, the material can be configured such that, once the applied pressure has exceeded a switching pressure, the resistance of the material can switch from the first resistance to the second resistance. | 12-15-2011 |
20110306968 | HEAT MANAGEMENT CONFIGURATIONS FOR CONTROLLING HEAT DISSIPATION FROM ELECTROSURGICAL INSTRUMENTS - In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise at least one energy delivery surface and heat dissipation means for dissipating heat from at least a portion of the end effector. For example, in at least one embodiment, the end effector may comprise a first jaw, a second jaw, and a cutting member. The cutting member may comprise a cutting surface and a body, which may define a cavity and at least one opening communicating with the cavity. A fluid may be moved through the cavity to and/or from the opening(s). Additionally, in at least one embodiment, a surgical instrument's end effector may comprise a first jaw, a second jaw, a cutting member, and at least one heat pipe. Various other heat dissipation means are also disclosed. | 12-15-2011 |
20120010616 | SURGICAL INSTRUMENT COMPRISING AN ARTICULATABLE END EFFECTOR - An electrosurgical instrument can comprise a handle, a shaft, and an end effector, wherein the end effector can be rotatably coupled to the shaft by an articulation joint. The instrument can further comprise a drive member and the articulation joint can comprise flexible support members which can be configured to support the drive member. The instrument can further comprise supply wires electrically coupled to electrodes in the end effector and a wire tensioning device configured to prevent the supply wires from accumulating slack within the articulation joint. The drive member can comprise a plurality of flexible layers wherein some of the layers can be comprised of an electrically insulative material and other layers can be comprised of an electrically conductive material which is in electrical communication with a cutting member in the end effector and/or electrodes positioned within the end effector. | 01-12-2012 |
20120012636 | SURGICAL INSTRUMENTS WITH ELECTRODES - A surgical stapling assembly is configured to be used to form a tissue seal having an arcuate portion. The surgical stapling assembly comprises an end-effector extending from the distal end of the shaft. The end-effector comprises a first portion and a second portion. The first portion comprises a first face at least partially surrounding the aperture, a staple cavity defined in the first face, a staple removably positioned within the staple cavity, and a first electrode positioned one of on and proximate to the first face. The second portion comprises a second face, an anvil pocket defined in the second face, and a second electrode positioned one of on and proximate to the second face, and a second electrode. The first electrode and the second electrode each comprise an arcuate portion. The first electrode has a different polarity than the second electrode. | 01-19-2012 |
20120012638 | SURGICAL INSTRUMENTS WITH ELECTRODES - An end-effector assembly configured to be attached to a surgical instrument. The end-effector assembly comprises a first jaw and a second jaw comprising a staple cavity. At least one of the first jaw and the second jaw is movable relative to the other jaw. The end-effector assembly comprises a staple removably positioned within the staple cavity and an electrically-conductive driver configured to move the staple between a first stored position in which the staple is at least partially positioned within the staple cavity and a second position in which the staple is at least partially deployed from the staple cavity into tissue positioned intermediate the first jaw and the second jaw. The staple comprises an electrode. | 01-19-2012 |
20120059396 | Device For Deploying A Fastener For Use In A Gastric Volume Reduction Procedure - A method and device for manipulating gastric tissue about a greater curvature of a stomach. The method includes the steps of creating at least one incision to gain access to the peritoneal cavity, and dissecting at least a portion of the greater omentum. Then the method includes accessing the exterior of the gastric tissue through the incision and folding at least a portion of the greater curvature of the stomach. The fold is constructed having serosa to serosa contact substantially along its entire length. The method further involves securing the fold with a flexible member wherein the flexible member comprises at least one tissue securing feature. | 03-08-2012 |
20120080495 | RELOADABLE LAPAROSCOPIC FASTENER DEPLOYING DEVICE - A device for deploying fasteners including a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The device also includes an elongated pusher movable through the hollow housing from the proximal to the distal end to deploy the fasteners. The device further includes a deforming member for deforming the pusher at a proximal end thereof while advancing the pusher to the distal end of the housing. | 04-05-2012 |
20120111919 | Surgical Stapler Fastening Device - A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means. | 05-10-2012 |
20120125971 | Surgical Stapler Fastening Device - A fastener applying device including a staple housing having a proximal end attached to a handle, a distal end, and a longitudinal axis therebetween. There is at least one fastener within the housing. The device also includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device also includes an adjustment nut connecting the staple housing to the handle. Rotation of the adjustment nut changes the distance. | 05-24-2012 |
20120160890 | Surgical Fastener for Applying A Large Staple Through A Small Delivery Port - A surgical fastener applying device having a handle with a trigger pivotably attached thereto and movable within a trigger plane. The trigger has a bottom portion extending from the handle and a top portion disposed within a housing of the handle. The device has a staple housing with a proximal end attached to the handle, a distal end extending therefrom and a longitudinal axis therebetween. The housing has a firing bar disposed within, and the trigger is coupled to the firing bar. The device has a link member with a first end pivotably attached to the top portion of trigger, the link member has a second end comprising a slidable pin. The pin engages a three dimensional cam path disposed within the housing. The link member follows distal and proximal movement of the top portion of the trigger, and the pin slides perpendicular to the trigger plane to follow the three dimensional cam path. | 06-28-2012 |
20120160891 | Method of Using A Surgical Stapler To Secure A Tissue Fold - A method of plicating a hollow organ by accessing the exterior of a hollow organ of a patient. The method includes the steps of grasping tissue on first and second sides of a greater curvature of the organ and forming a first fold along a length the greater curvature by attaching the first and second sides together along a first attachment line with a first plurality of fasteners. The fasteners have a first spacing therebetween. The method also involves the steps of grasping tissue on first and second sides of a greater curvature of the organ and forming a second fold about the first fold along a length the first attachment line by attaching the first and second sides together along a second attachment line with a second plurality of fasteners having a second spacing therebetween. Wherein the second spacing is less than the first spacing and wherein the second spacing is less than 2 cm. | 06-28-2012 |
20120165604 | ENDOLUMINAL FOLD CREATION - Devices and methods are provided for forming one or more plications in the walls of a body cavity. In particular, endoscopic devices and methods are provided for forming and/or securing endoluminal tissue folds to reduce the volume of the gastric cavity. An end effector that includes a tissue receiving cavity can be delivered to a desired surgical site to allow a tissue fold to be formed within the tissue receiving cavity. A fastener can be used to secure the adjacent layers of tissue that form the tissue fold. The tissue folds can be effective to limit the stomach's capacity and create a feeling of satiety. | 06-28-2012 |
20120165792 | Pill Catchers - Devices and related methods arc provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete. administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs. | 06-28-2012 |
20120165793 | Pill Catchers - Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs. | 06-28-2012 |
20120165794 | Pill Catchers - Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs. | 06-28-2012 |
20120165796 | Pill Catchers - Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs. | 06-28-2012 |
20120165842 | ENDOLUMINAL FOLD CREATION - Devices and methods are provided for forming one or more plications in the walls of a body cavity. In particular, endoscopic devices and methods are provided for forming and/or securing endoluminal tissue folds to reduce the volume of the gastric cavity. An end effector that includes a tissue receiving cavity can be delivered to a desired surgical site to allow a tissue fold to be formed within the tissue receiving cavity. A fastener can be used to secure the adjacent layers of tissue that form the tissue fold. The tissue folds can be effective to limit the stomach's capacity and create a feeling of satiety. | 06-28-2012 |
20120172783 | OBESITY THERAPY AND HEART RATE VARIABILITY - Methods and devices are provided for delivering obesity therapy to a patient. In general, the methods and devices allow for onset of a patient eating solid food, e.g., the patient beginning a meal, to trigger delivery of an obesity therapy to a patient. The obesity therapy can be delivered to the patient for a limited period of time such that the patient stops receiving the obesity therapy prior to a second onset of the patient eating solid food, e.g., the patient beginning a second meal, which can trigger a second delivery of the obesity therapy to the patient for a limited period of time. | 07-05-2012 |
20120172792 | OBESITY THERAPY AND HEART RATE VARIABILITY - Methods and devices are provided for delivering obesity therapy to a patient. In general, the methods and devices allow for onset of a patient eating solid food, e.g., the patient beginning a meal, to trigger delivery of an obesity therapy to a patient. The obesity therapy can be delivered to the patient for a limited period of time such that the patient stops receiving the obesity therapy prior to a second onset of the patient eating solid food, e.g., the patient beginning a second meal, which can trigger a second delivery of the obesity therapy to the patient for a limited period of time. | 07-05-2012 |
20120193394 | Surgical Stapler Having an Adjustment Feature - A fastener applying device for surgically attaching tissue together. The device includes a staple housing having a proximal end attached to a handle, a distal end and a longitudinal axis therebetween. There is at least one fastener within the housing. The device includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device further includes an adjustment nut connecting the staple housing to the handle, wherein rotation of the adjustment nut changes the distance. | 08-02-2012 |
20120193399 | Surgical Fastener Having A Safety Feature - A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing having a proximal position and a distal position. When the anvil is in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop, wherein at least one fasteners is placed around the anvil when the anvil is in distal position. And a distal end of the anvil extends distal to the distal end of the staple housing. The applier further includes a first means for moving the anvil distally during a deployment of the at least one fastener, and a second means for moving the anvil distally during the deployment of the at least one fastener, wherein the second means is independent of the first means. | 08-02-2012 |
20120330329 | METHODS OF FORMING A LAPAROSCOPIC GREATER CURVATURE PLICATION USING A SURGICAL STAPLER - A method of plicating a stomach by accessing the exterior of a stomach of a patient and grasping tissue on a first and second location on a first side of the greater curvature of the stomach. Also forming a plication therebetween with a first staple. The method involves grasping tissue on a third and fourth location on a second side of the greater curvature of the stomach and forming a plication with a second staple. The first and second plications are near a location selected from the group consisting of a gastroesophageal junction, a pylorus, and an incisura angularis. The method further includes grasping tissue on a first and second side of a greater curvature of the stomach and forming a fold along a length of the greater curvature by attaching the first and second sides together along a first attachment line with a first plurality of staples. | 12-27-2012 |
20130023875 | SURGICAL INSTRUMENTS FOR TENSIONING TISSUE - A surgical instrument can comprise an end effector including a plurality of jaws which can be configured to compress tissue therebetween. The end effector can further comprise one or more electrodes which can be configured to direct a flow of electrical current through the tissue in order to heat the tissue and denature collagen and/or other proteins within the tissue. As the tissue cools, the collagen and/or other proteins can renature and thereby seal the tissue. In certain embodiments, the end effector of the surgical instrument can further comprise movable portions which can apply a tension force to the tissue surrounding the tissue being sealed. In various circumstances, the tension force can reduce the over-denaturation, shrinkage, and/or other damage to the surrounding tissue caused by heat flowing from the end effector during the sealing process. | 01-24-2013 |
20130030350 | Devices and Methods for Anchoring an Endoluminal Sleeve in the GI Tract - An endoluminal sleeve device for internally lining a section of the GI tract, comprises a sleeve configured for deployment inside a duodenum, the sleeve having walls of a flexible material defining a sleeve lumen, a proximal end defining a proximal lumen opening, and a distal end defining a distal lumen opening, an anchoring component having a slender transport configuration and a bulky deployed configuration, wherein the anchoring component is locatable at a distance from the proximal sleeve end and connected thereto by an elongated tether. | 01-31-2013 |
20130053831 | SURGICAL CUTTING AND FASTENING DEVICE WITH DESCENDIBLE SECOND TRIGGER ARRANGEMENT - A nested trigger assembly for a surgical instrument may generally comprise a first trigger and a second trigger, wherein the first trigger and the second trigger are movable together on a first stroke of the nested trigger assembly, wherein the second trigger is configured to be biased away from the first trigger after the first stroke and before a second stroke, and wherein the second trigger is configured to be moved toward to the first trigger during the second stroke. A surgical instrument may generally comprise a shaft comprising a proximal end and a distal end, a handle extending from the proximal end, wherein the handle comprises a gripping portion, and a nested trigger assembly extending from the handle. The nested trigger assemble may comprise one of a separable trigger assembly and a divisible trigger assembly. | 02-28-2013 |
20130116218 | METHODS AND COMPOSITIONS OF BILE ACIDS - Methods and compositions are provided for treating metabolic disorders by modulating bile acid levels. Generally, the methods and compositions can modulate bile acid levels, such as serum bile acid levels, to treat a metabolic disorder. In one embodiment, a method of modulating a bile acid level includes measuring a bile acid level and delivering a composition effective to modulate the bile acid level. A method for modulating a bile acid profile includes comparing a bile acid profile to a target profile and delivering a bile acid cocktail to increase bile acid levels. In another embodiment, a pharmaceutical composition for increasing bile acid levels includes a bile acid cocktail effective to increase bile acid levels. The composition is further useful as part of an implantable system. | 05-09-2013 |
20130153622 | DEVICES AND METHODS FOR ENDOLUMINAL PLICATION - Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a method of acquiring and fixating tissue is disclosed that includes inserting a surgical device having first and second jaws and a tissue acquisition member into a body lumen, positioning the device in a first position in which the jaws extend substantially parallel to a tissue surface, drawing tissue through the jaws by moving the tissue acquisition member away from the jaws, and driving at least one fastener through the tissue disposed between the jaws. | 06-20-2013 |
20130153623 | DEVICES AND METHODS FOR ENDOLUMINAL PLICATION - Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a tissue acquisition and fixation system is disclosed that includes an elongate shaft, an end effector coupled to the elongate shaft and having first and second jaws, and a tissue acquisition member coupled to the end effector by a linkage assembly. At least a portion of the linkage assembly and tissue acquisition member are slidably movable in a direction parallel to a longitudinal axis of the jaws. Further, the tissue acquisition member is vertically movable relative to the end effector such that a distance between a longitudinal axis of the tissue acquisition member and the jaws can be adjusted. | 06-20-2013 |
20130153624 | DEVICES AND METHODS FOR ENDOLUMINAL PLICATION - Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a tissue acquisition and fixation system is disclosed including a stapling member having first and second jaws that are effective to apply at least one staple to tissue engaged between the jaws, a tissue acquisition member coupled to at least one of the first and second jaws, and a secondary tissue acquirer coupled to the tissue acquisition member. The secondary tissue acquirer is configured to engage tissue and maintain the tissue in position relative to the tissue acquisition member. | 06-20-2013 |
20130153625 | DEVICES AND METHODS FOR ENDOLUMINAL PLICATION - Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a tissue acquisition and fixation system is disclosed that includes an elongate shaft, a staple applying assembly having a proximal end coupled to the distal end of the elongate shaft and having first and second jaws, and a tissue acquisition member coupled to the staple applying assembly by a linkage mechanism. The linkage mechanism is configured to move the tissue acquisition member between a first position that is longitudinally offset and proximal to the staple applying assembly, and a second position that is longitudinally adjacent to the staple applying assembly. | 06-20-2013 |
20130153626 | DEVICES AND METHODS FOR ENDOLUMINAL PLICATION - Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a method of gastric volume reduction is disclosed that includes advancing a tissue acquisition and fixation device endoscopically into a stomach, manipulating the device to form a first fold of tissue on an interior surface of an anterior wall of the stomach, and manipulating the device to form a second fold of tissue on an interior surface of a posterior wall of the stomach, where the second fold is not attached to the first fold. | 06-20-2013 |
20130153642 | DEVICES AND METHODS FOR ENDOLUMINAL PLICATION - Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a tissue acquisition and fixation system is described that includes a staple applying assembly having first and second jaws, and a tissue acquisition member that extends substantially parallel to a plane running through the first and second jaws. The tissue acquisition member is effective to engage and position tissue between the first and second jaws, and the jaws are effective to apply at least one staple to the tissue engaged therebetween. | 06-20-2013 |
20130193183 | SURGICAL STAPLER FASTENING DEVICE - A fastener applying device including a staple housing having a proximal end attached to a handle, a distal end, and a longitudinal axis therebetween. There is at least one fastener within the housing. The device also includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device also includes an adjustment nut connecting the staple housing to the handle. Rotation of the adjustment nut changes the distance. | 08-01-2013 |
20130193184 | SURGICAL STAPLER FASTENING DEVICE - A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means. | 08-01-2013 |
20130224155 | COMPOSITIONS OF MICROBIOTA AND METHODS RELATED THERETO - Methods and compositions are generally provided for treating metabolic disorders, e.g., obesity. One aspect discloses methods and compositions for obtaining a biological sample from the subject, evaluating the sample for the presence or absence of a genetic indicator, wherein the genetic indicator is selected from a single nucleotide polymorphism and a level of gene expression, and performing a first metabolic procedure if the genetic indicator is present, or performing an alternative second metabolic procedure if the genetic indicator is absent. One aspect discloses methods and compositions for obtaining a sample including deoxyribonucleic acids (DNA) from the subject, evaluating the DNA for an absence or presence of one or more genetic indicators and performing a first metabolic procedure or an alternative second metabolic procedure based on the absence or presence of the genetic indicator(s). Other aspects are also disclosed. | 08-29-2013 |
20130253536 | METHODS AND DEVICES FOR CREATING TISSUE PLICATIONS - Devices and methods for forming and securing a tissue plication are disclosed herein. In one aspect, a tissue manipulation device is described that includes a first jaw member pivotally coupled to a distal end of an elongate shaft and having an articulating portion located distal to the proximal end of the first jaw member. The device also includes a second jaw member pivotally coupled to the first jaw member such that the jaws move in a first plane, and a fastener delivery member attached to the second jaw member. The articulating portion of the first jaw member is configured to move the first and second jaw members between a straight configuration in which a longitudinal axis of the elongate shaft is contained within the first plane and an articulated configuration in which the longitudinal axis of the elongate shaft is transverse to the first plane. | 09-26-2013 |
20130304175 | Device and Method for Self-Positioning of a Stimulation Device to Activate Brown Adipose Tissue Depot in a Supraclavicular Fossa Region - Self-positioning of at least a portion of a transdermal electrical stimulation patch within a target area (e.g., supraclavicular fossa region) of a human body to activate a depot of brown adipose tissue therein. An electric field is generated using the electrical stimulation patch to activate the brown adipose tissue within the supraclavicular fossa region of the body. The patch is self-positioned using one or more anatomical points (e.g., anatomical landmarks and/or anatomical features) or markings on the body. Brown adipose tissue may also be activated by applying an electrical signal to a body piercing partially implanted proximate a target area in which the tissue is disposed. | 11-14-2013 |
20140087999 | CLINICAL PREDICTORS OF WEIGHT LOSS - Methods and compositions are generally provided for treating metabolic disorders, e.g., obesity. One aspect discloses methods and compositions for obtaining a biological sample from the subject, evaluating the sample for the presence or absence of a genetic indicator, wherein the genetic indicator is selected from a single nucleotide polymorphism and a level of gene expression, and performing a first metabolic procedure if the genetic indicator is present, or performing an alternative second metabolic procedure if the genetic indicator is absent. One aspect discloses methods and compositions for obtaining a sample including deoxyribonucleic acids (DNA) from the subject, evaluating the DNA for an absence or presence of one or more genetic indicators and performing a first metabolic procedure or an alternative second metabolic procedure based on the absence or presence of the genetic indicator(s). Other aspects are also disclosed. | 03-27-2014 |
20140194915 | ELECTROSURGICAL CUTTING AND SEALING INSTRUMENTS WITH JAWS HAVING A PARALLEL CLOSURE MOTION - Various embodiments are directed to a surgical instrument comprising, a shaft, and an end effector. The shaft may be coupled to the handle and may extend distally along a longitudinal axis. The end effector may be positioned at a distal end of the shaft and may comprise first and second jaw members and a reciprocating member. The first and second jaw members may define first and second longitudinal slots. The reciprocating member may be translatable distally and proximally parallel to the longitudinal axis and through the first and second longitudinal slots. A distal portion of the reciprocating member may define a blade. The end effector may additionally comprise a first push rod member having a distally directed end pivotably coupled to the first jaw member and a proximally directed end pivotably coupled to the shaft at a first pivot point as well as a first linkage member having a distally directed end pivotably coupled to the first jaw member and a proximally directed end pivotably coupled to a second pivot point. In this way, distal motion of the reciprocating member may exert a force on the first and second jaw members causing the first and second jaw members to translate towards one another in a substantially parallel motion. | 07-10-2014 |
20140275748 | MEAL DETECTION DEVICES AND METHODS - Devices and methods for detecting meal intake are disclosed herein. In some embodiments, one or more sensors can be used to detect or monitor physiological parameters of a user (e.g., heart rate, body movements, temperature, pH, impedance, gastric stretch, sound emissions, and the like). The outputs of the sensors can be received by a computer system configured to analyze the sensor data and make a determination as to whether meal intake has occurred or is presently occurring. The computer system's determination can be used to trigger, modulate, or otherwise control one or more therapeutic devices. Other types of devices can also be controlled using this determination, such as monitoring or logging devices. | 09-18-2014 |
20140276761 | ELECTROSURGICAL DEVICE WITH DISPOSABLE SHAFT HAVING TRANSLATING GEAR AND SNAP FIT - An apparatus includes an interface assembly and a shaft assembly. The interface assembly is configured for use with a robotic system and includes a first drive assembly and a mounting plate. The mounting plate includes an opening. The first drive assembly is positioned within the opening such that the first drive assembly is laterally translatable within the opening from a first position to a second position. The shaft assembly is removably coupled with the interface assembly. The shaft assembly comprises an end effector and a first coupling feature. The first drive assembly of the interface assembly actuates the end effector of the shaft assembly. The first coupling feature is longitudinally aligned with the first drive assembly. The first drive assembly engages the first coupling feature of the shaft assembly when the first drive assembly is laterally translated from the first position to the second position. | 09-18-2014 |
20150045850 | DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS - An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device ( | 02-12-2015 |