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Jarvis, CO

Eric Jarvis, Boulder, CO US

Patent application numberDescriptionPublished
20100093838REGULATION OF ANGIOGENESIS WITH ZINC FINGER PROTEINS - Provided herein are a variety of methods and compositions for regulating angiogenesis, such methods and compositions being useful in a variety of applications where modulation of vascular formation is useful, including, but not limited to, treatments for ischemia and wound healing. Certain of the methods and compositions accomplish this by using various zinc finger proteins that bind to particular target sites in one or more VEGF genes. Nucleic acids encoding the zinc finger proteins are also disclosed. Methods for modulating the expression of one or more VEGF genes with the zinc finger proteins and nucleic acids are also disclosed. Such methods can also be utilized in a variety of therapeutic applications that involve the regulation of endothelial cell growth. Pharmaceutical compositions including the zinc finger proteins or nucleic acids encoding them are also provided.04-15-2010
20100144041 L-Arabinose Fermenting Yeast - An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. Methods of producing ethanol include utilizing these modified yeast strains.06-10-2010

Patent applications by Eric Jarvis, Boulder, CO US

Eric Edward Jarvis, Boulder, CO US

Patent application numberDescriptionPublished
20100186438SUB-WET BULB EVAPORATIVE CHILLER WITH PRE-COOLING OF INCOMING AIR FLOW - An evaporative chiller cooling water to below ambient wet bulb temperature. Sub-wet bulb chilling is achieved by pre-cooling incoming air upstream of the saturator. The incoming air is ambient air at ambient air temperature that is cooled using the coolness of the lower temperature outgoing air exiting the saturator. The pre-cooling lowers the temperature of the incoming air and lowers its wet bulb temperature below that of ambient air. The saturator water is chilled to below the ambient wet bulb temperature. The air in the saturator flows across the water as it gravity drips or flows from the top to the bottom of the saturator. The pre-cooled air flows across the saturator with the coolest air directed across the bottom of the saturator where the coldest water is flowing and with the hottest air directed across the top where the hottest water is flowing to provide gradient chilling.07-29-2010
20100261271Regulation of endogenous gene expression in cells using zinc finger proteins - The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.10-14-2010
20100279406Alteration of tumor growth using zinc finger proteins - The present invention provides methods for altering tumor growth using zinc finger proteins.11-04-2010
20110247087Regulation of endogenous gene expression in cells using zinc finger proteins - The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.10-06-2011

Patent applications by Eric Edward Jarvis, Boulder, CO US

Thale Jarvis, Boulder, CO US

Patent application numberDescriptionPublished
20080207703Antibacterial heterocyclic ureas - The present invention provides novel heterocyclic urea compounds having useful antibacterial activity, pharmaceutical compositions comprising one or more of these compounds, methods of making the same, and methods of using the same.08-28-2008
20100286169Antibacterial Sulfone and Sulfoxide Substituted Heterocyclic Urea Compounds - The present invention provides novel sulfone and sulfoxide substituted heterocyclic urea compounds having useful antibacterial activity. Use of these compounds as pharmaceutical compositions and methods of production are provided.11-11-2010
20120015941Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds - The present invention provides novel amide and sulfonamide substituted heterocyclic urea compounds having useful antibacterial activity. Use of these compounds as pharmaceutical compositions and method of their production are also provided.01-19-2012

Patent applications by Thale Jarvis, Boulder, CO US

Thale C. Jarvis, Boulder, CO US

Patent application numberDescriptionPublished
20120115752Method for Generating Aptamers with Improved Off-Rates - The present disclosure describes the identification and use of aptamers and photoaptamers having slower dissociation rate constants than those obtained using previously described methods. Specifically, the present disclosure describes methods for the identification and use of aptamers to one or more targets within a histological or cytological sample, which have slow rates of dissociation. The aptamers may be used to assess localization, relative density, and presence or absence of one or more targets in cytological and histological samples. Targets may be selected that are specific and diagnostic of a given disease state for which the sample was collected. The aptamers may also be used to introduce target specific signal moieties. In addition to target identification, the aptamers may be used to amplify signal generation through a variety of methods.05-10-2012

Thale Cross Jarvis, Boulder, CO US

Patent application numberDescriptionPublished
20100028862BACTERIAL REPLICATION SYSTEMS AND METHODS - Reconstituted bacterial replication assemblies and methods for their use are provided.02-04-2010