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Janssens, NL

Abraham Janssens, Breda NL

Patent application numberDescriptionPublished
20080267378Conference System - A conference system (10-30-2008

Gijs Janssens, Beilen NL

Patent application numberDescriptionPublished
20120000032VACUUM CLEANER - A vacuum cleaner (01-05-2012

Jan Arnaud Janssens, Deventer NL

Patent application numberDescriptionPublished
20110236601Method for Depositing a Material - The invention relates to a method for depositing a material for a target onto a surface of a sample, which method comprises the steps of: irradiating a surface of the target with a laser or electron beam to generate a plume of target material particles; positioning the sample near the plume, such that the target material particles are deposited onto the surface of the sample; rotating the sample around a rotation axis being perpendicular to the surface of the sample onto which the particles are deposited; moving the laser beam along the surface of the target, such that the plume moves in a radial direction in relation to the rotation axis; pulsing the laser beam at a variable frequency.09-29-2011
20110292354Device for Projecting an Image on a Surface and Device for Moving Said Image - The invention relates to a device for projecting an image on a surface, comprising: a light source generating a light beam; a mask arranged in the path of the light beam; a lens arranged behind the mask to focus the image of the mask on a surface, wherein the surface is not parallel to the lens, wherein at substantially each position along the edges of the mask the distance v to the lens and the distance b of the corresponding position at the edges of the image of the mask to the lens correspond substantially to the formula 1/v+1/b=1/f, wherein f is the focal length of the lengths. The invention also relates to a device for moving the image on the surface.12-01-2011

Jean-Paul Janssens, Vlaardingen NL

Patent application numberDescriptionPublished
20110054215PREPARATION OF FREE FLOWING GRANULES OF METHYLGLYCINE DIACETIC ACID - The present invention concerns a process for the preparation of free flowing granules of low hygroscopicity of one or more methylglycine diacetic acid (MGDA) salts, of the formula wherein R=CH3 and M is hydrogen, alkali metal, alkaline earth metal, ammonium or substituted ammonium in the appropriate stoechiometric amounts, by a process comprising the steps of i) heating a concentrated slurry comprising methylglycine diacetic acid (MGDA) and/or any salts thereof, the slurry having a solids content content in the range of 45% to 70% and suitably in the range from 50% to 70%, and a moisture content of 30% up to 55%, and suitably between 30% and 50%, to a temperature in the range of 50 to 120° C., preferably to about 80° C., and ii) spray granulating said slurry, using an air inlet temperature of 120° C. or less.03-03-2011

Marcel Henk Andre Janssens, Delft NL

Patent application numberDescriptionPublished
20090201483Polarization Control Apparatus and Method - Apparatus and methods are used to control a polarization state of a radiation beam. A polarization control unit is configured to modulate a polarization state of at least a part of a radiation beam. A determination arrangement is configured to subsequently determine the polarization state of the at least a part of the radiation beam. A feedback unit is configured to provide signals to the polarization control arrangement based on at least the determined polarization state in order to correct for deviation in the polarization state of the part of the radiation beam from a desired polarization state. For example, the correction may ensure that the polarization state of the part of the radiation beam is at, or returns to, the desired polarization state.08-13-2009

Richard Wilhelm Janssens, Rotterdam NL

Patent application numberDescriptionPublished
20090169548BINDING MOLECULES - The present invention relates to the manufacture of mono, di and multivalent polypeptide binding complexes, also mono, di or multispecific polypeptide binding complexes and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of antigen specific VH binding domains derived from phage display libraries, transgenic animals or natural sources. Preferably the VH binding domains and the dimerisation domains comprise human sequences. The polypeptide binding complexes comprise homo or heterodimerisation domains with four antigen binding [VH] domains fused at the amino and carboxyl termini of the dimerisation domains preferably using natural hinge or linker peptides. Where the polypeptide binding complexes lack CH2-CH3 effector functions they are preferably less than 120 kDa in size. Routes of manufacture are described herein.07-02-2009
20090271880BINDING MOLECULES - The present invention relates to methods for engineering VH domains to improve their solubility and stability. The invention provides for the incorporation of defined amino acid substitutions based on 3-D structural information into the V segments of a heavy chain locus, expressing the locus in a non-human mammal and selecting soluble VH domains. Further stabilising or solubilising mutations maybe introduced as a result affinity maturation during B-cell maturation in vivo.10-29-2009
20090285805Binding molecules - The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of class-specific heavy chain-only antibodies and to the manufacture and use of multivalent polypeptide complexes with antibody heavy chain functionality, preferably antibody heavy chain binding functionality, constant region effector activity and, optionally, additional effector functions. The present invention also relates to a method of generation of fully functional heavy chain-only antibodies in transgenic mice in response to antigen challenge. In particular, the present invention relates to a method for the generation of human antigen-specific, high affinity, heavy chain-only antibodies of any class, or mixture of classes and the isolation and expression of fully functional VH antigen-binding domains.11-19-2009
20090307787GENERATION OF HEAVY-CHAIN ONLY ANTIBODIES IN TRANSGENIC ANIMALS - The present invention relates to a method for the generation of V12-10-2009

Richard Wilhelm Janssens, Dr Rotterdam NL

Patent application numberDescriptionPublished
20110314563ANTIBODY PRODUCTION - A non-human mammal containing an endogenous lambda light chain gene locus, an endogenous kappa light chain gene locus and an endogenous heavy chain gene locus, each of which can re-arrange so that immunoglobulin heavy and light chain genes are formed and expressed in B-cells following antigen challenge but said loci have been mutated so that the ability to form functional immunoglobulin tetramers comprising re-arranged heavy and light chains produced from said mutated loci has been substantially reduced or eliminated.12-22-2011

Richard Willhelm Janssens, Rotterdam NL

Patent application numberDescriptionPublished
20100197897BINDING MOLECULES - The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of class-specific heavy chain-only antibodies and to the manufacture and use of multivalent polypeptide complexes with antibody heavy chain functionality, preferably antibody heavy chain binding functionality, constant region effector activity and, optionally, additional effector functions.08-05-2010
20100216974BINDING MOLECULES - The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of class-specific heavy chain-only antibodies and to the manufacture and use of multivalent polypeptide complexes with antibody heavy chain functionality, preferably antibody heavy chain binding functionality, constant region effector activity and, optionally, additional effector functions.08-26-2010
20110118444BINDING MOLECULES - The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of class-specific heavy chain-only antibodies and to the manufacture and use of multivalent polypeptide complexes with antibody heavy chain functionality, preferably antibody heavy chain binding functionality, constant region effector activity and, optionally, additional effector functions.05-19-2011