Jansen, CA
Burkhard Jansen, Vancouver CA
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20080274996 | RNAi Probes Targeting Cancer-Related Proteins - RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease. These sequences target clusterin, IGFBP-5, IGFBP-2, both IGFBP-2 and -5 simultaneously, Mitf, and B-raf. The invention further provides for the use of these RNAi sequences in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease, and a method of treating such conditions through the administration of the RNA molecules with RNAi activity to an individual, including a human individual in need of such treatment. | 11-06-2008 |
20110009472 | RNAi Probes Targeting Cancer-Related Proteins - RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease. These sequences target clusterin, IGFBP-5, IGFBP-2, both IGFBP-2 and -5 simultaneously, Mitf, and B-raf. The invention further provides for the use of these RNAi sequences in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease, and a method of treating such conditions through the administration of the RNA molecules with RNAi activity to an individual, including a human individual in need of such treatment. | 01-13-2011 |
20120202873 | RNAi Probes Targeting Cancer-Related Proteins - RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease. These sequences target clusterin, IGFBP-5, IGFBP-2, both IGFBP-2 and -5 simultaneously, Mitf, and B-raf. The invention further provides for the use of these RNAi sequences in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease, and a method of treating such conditions through the administration of the RNA molecules with RNAi activity to an individual, including a human individual in need of such treatment. | 08-09-2012 |
Christian Jansen, Etobicoke CA
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20090176608 | Overrunning Alternator Decoupler Pulley with Bare Wire Spring and Grease Lubrication - A decoupler assembly is provided for a system that employs an endless power transmitting element. The decoupler includes a one-way clutch with a wrap spring and a torsion spring that are disposed between a pulley, which is engaged to the endless power transmitting element, and a hub. The one-way clutch permits overrunning of a driven or output one of the pulley and the hub, whereas the torsion spring stores and releases energy to attenuate the response of the one-way clutch in a manner that provides improved durability of an interface between the wrap spring and the pulley. | 07-09-2009 |
Christian Jansen, Thornhill CA
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20100140044 | Crankshaft Torque Modulator - A decoupler with driven and driving members, a clutch, a torsional vibration damper and a lubricant. The clutch is received in a bore in the driven member and includes a carrier, a wrap spring and at least one spring. The wrap spring is formed of spring wire and has a plurality of coils disposed between a first end, which is received in a groove in the carrier, and a second end. The portion of the wrap spring outside the carrier has an outer circumferential spring surface that is abutted against the inner circumferential surface of the bore. The at least one spring is disposed between the carrier and the driving member to transmit rotary power from the driving member to the carrier. The torsional vibration damper is coupled to the driving member for rotation therewith. The lubricant is disposed on the remaining portion of the wrap spring. | 06-10-2010 |
20100178990 | DECOUPLER WITH SPRING TRAVEL LIMITER - A decoupler having an output member, a one-way clutch, a spring and a spring limiter. The spring is disposed between an output portion of the one-way clutch and the output member to bias the output portion in a predetermined rotational direction relative to the output member. The spring limiter can be configured to lock an output of the one-way clutch to the output member to transmit rotary power between the one-way clutch and the output member without stressing the spring beyond a predetermined point and/or to limit rotational movement of the output portion and an associated end of the spring relative to the output member in the predetermined rotational direction. A method for operating a decoupler is also provided. | 07-15-2010 |
20130056328 | CRANKSHAFT TORQUE MODULATOR - A decoupler with driven and driving members, a clutch, a torsional vibration damper and a lubricant. The clutch is received in a bore in the driven member and includes a carrier, a wrap spring and at least one spring. The wrap spring is formed of spring wire and has a plurality of coils disposed between a first end, which is received in a groove in the carrier, and a second end. The portion of the wrap spring outside the carrier has an outer circumferential spring surface that is abutted against the inner circumferential surface of the bore. The at least one spring is disposed between the carrier and the driving member to transmit rotary power from the driving member to the carrier. The torsional vibration damper is coupled to the driving member for rotation therewith. The lubricant is disposed on the remaining portion of the wrap spring. | 03-07-2013 |
David Wainesworth Jansen, Waterloo CA
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20110204820 | CONFIGURABLE LED DRIVER/DIMMER FOR SOLID STATE LIGHTING APPLICATIONS - The disclosure is directed at a configurable light emitting diode (LED) driver/dimmer for controlling a set of light fixture loads comprising: a power circuit; a primary digital controller for controlling the power circuit; a set of output current drivers, each of the set of output current drivers connected to one of the set of light fixture loads for controlling the associated light fixture load; a secondary digital controller for controlling the set of output current drivers; wherein the secondary controller transmits LED control information to control outputs of the set of output current drivers; and wherein the secondary digital controller provides digital feedback control information to the primary digital controller. | 08-25-2011 |
Herbert Jansen, Montreal CA
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20140031829 | METHOD AND SYSTEM FOR CREATING FRAME OF REFERENCE FOR CAS WITH INERTIAL SENSORS - A digitizer device comprises an elongated body and legs connected to the elongated body. At least one joint is between the legs and the elongated body such that free ends of the legs are displaceable relative to one another. An inertial sensor unit is connected to the elongated body, the inertial sensor unit having a preset orientation aligned with the elongated body. A table reference device comprises a body adapted to be fixed to an operating table. An inertial sensor unit is with a preset orientation related to the operating table. A patient coordinate system comprising orientation data obtained from the inertial sensor units of the digitizer device and the table reference device | 01-30-2014 |
20140364858 | ACETABULAR CUP PROSTHESIS POSITIONING INSTRUMENT AND METHOD - A method for assisting in positioning the acetabular cup comprises orienting a cup positioning instrument with a cup thereon in an initial reference orientation relative to an acetabulum of a pelvis with the cup forming a joint with the acetabulum, the cup positioning instrument comprising an inertial sensor unit with pre-planned orientation data for a desired cup orientation based on at least one landmark of the pelvis, The cup positioning instrument is rotated to a desired abduction angle as guided by an interface of the cup positioning instrument, based on movements relative to at least one landmark. The cup positioning instrument is rotated to a desired anteversion angle as guided by the interface of the cup positioning instrument, based on movements relative to the at least one landmark. Upon reaching the desired cup orientation as indicated by the interface, the cup is impacted into the acetabulum. | 12-11-2014 |
Herbert Andre Jansen, Montreal CA
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20090248044 | METHOD AND SYSTEM FOR PLANNING/GUIDING ALTERATIONS TO A BONE - A computer-assisted surgery system for planning/guiding alterations to a bone in surgery, comprises a trackable member adapted to be secured to the bone. The trackable member has a first inertial sensor unit producing orientation-based data for at least two degrees of freedom in orientation of the trackable member A positioning block is adapted to be secured to the bone, with at least an orientation of the positioning block being adjustable once the positioning block is secured to the bone to reach a selected orientation at which the positioning block is used to guide tools in altering the bone. The positioning block has a second inertial sensor unit producing orientation-based data for at least two degrees of freedom in orientation of the positioning block. A processing system providing an orientation reference associating the bone to the trackable member comprises a signal interpreter for determining an orientation of the trackable member and of the positioning block from the orientation-based data. A parameter calculator calculates alteration parameters related to an actual orientation of the positioning block with respect to the bone as a function of the orientation reference and of the orientation of the positioning block. | 10-01-2009 |
20130073067 | METHOD AND SYSTEM FOR PLANNING/GUIDING ALTERATIONS TO A BONE - A computer-assisted surgery system for guiding alterations to a bone, comprises a trackable member secured to the bone. The trackable member has a first inertial sensor unit producing orientation-based data. A positioning block is secured to the bone, and is adjustable once the positioning block is secured to the bone to be used to guide tools in altering the bone. The positioning block has a second inertial sensor unit producing orientation-based data. A processing system providing an orientation reference associating the bone to the trackable member comprises a signal interpreter for determining an orientation of the trackable member and of the positioning block. A parameter calculator calculates alteration parameters related to an actual orientation of the positioning block with respect to the bone. | 03-21-2013 |
20140316545 | METHOD AND SYSTEM FOR PLANNING/GUIDING ALTERATIONS TO A BONE - A computer-assisted surgery system for guiding alterations to a bone, comprises a trackable member secured to the bone. The trackable member has a first inertial sensor unit producing orientation-based data. A positioning block is secured to the bone, and is adjustable once the positioning block is secured to the bone to be used to guide tools in altering the bone. The positioning block has a second inertial sensor unit producing orientation-based data. A processing system providing an orientation reference associating the bone to the trackable member comprises a signal interpreter for determining an orientation of the trackable member and of the positioning block. A parameter calculator calculates alteration parameters related to an actual orientation of the positioning block with respect to the bone. | 10-23-2014 |
20150313723 | ACETABULAR CUP IMPACTING USING PATIENT-SPECIFIC INSTRUMENTATION - A cup impactor assembly comprises a shaft. A cup coupler is at a cup end of the shaft and is releasably connecting a cup in fixed relation. A handle is at an impacting end of the shaft. A visual guide is mounted to at least one of the shaft and the handle, the visual guide producing visual guidance for pointing at at least two landmarks of the pelvis or fixed relative to the pelvis, based on a pre-planned patient-specific relation between the at least two landmarks and a desired acetabular cup orientation relative to the landmarks. A method for orienting an acetabular cup prior to impacting in an acetabulum of a pelvis is also provided. | 11-05-2015 |
Herbert André Jansen, Montreal CA
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20110251835 | DEVICE, METHOD AND SYSTEM FOR DIGITIZING POSITION AND ORIENTATION INFORMATION OF HIP JOINT IMPLANT COMPONENTS | 10-13-2011 |
John Jansen, British Columbia CA
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20140209605 | CONTAINER WITH HANDS-FREE LATCH AND LINKAGE ACTIVATION FOR ACCESS - The invention pertains to a foot operated latch and linkage means permitting hands-free access to a waste or recycling container. The latch includes a kick plate which is interlocked with a foot pedal whereby displacement of the kick plate permits release of the foot pedal to move from a latched position to an unlatched position, which pedal movement engages a linkage which opens a user access door in the container. | 07-31-2014 |
Kirk Jansen, Abbotsford CA
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20140345104 | Manual King Pin Press - A king pin removal tool for displacing a king pin comprises a drive plate defining a drive opening, an anchor plate, a first drive member, a spacing system, and a stabilizing system. The spacing system supports the drive plate and the anchor plate relative to the king pin such that the first drive member is aligned with the king pin axis. The first drive member engages the drive plate such that rotation of the first drive member relative to the drive plate displaces the first drive member through the drive opening and along the king pin axis to displace the king pin along the king pin axis relative to the axle member and the knuckle assembly. The stabilizing system supports the drive plate to prevent rotation of the drive plate relative to the axle member when the first drive member is rotated relative to the drive plate. | 11-27-2014 |
Kirk Kenneth Jansen, Abbotsford CA
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20110010909 | PIN PULLER - A pin puller includes a coupler to connect a pull rod to an end of a pin. A follower attaches to a tail end of the pin. The coupler may comprise a pair of mating shells having features to engage the pin and pull rod. An actuator is configured to apply tension to the pull rod. The pin puller may be used to remove and install pins and associated bushings in truck suspensions and other applications. | 01-20-2011 |
Nathen Jansen, Chilliwack CA
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20090047638 | LEARNING SUPPORT METHOD AND SYSTEM - The present invention relates to a learning support method, in particular an Internet-based remote learning support method. This learning support method comprises the steps of determining a set of selection criteria for food preparation methods for preparing dishes or liquid drinks, said set of selection criteria comprising a proficiency level and at least one further selection criterion in the form of a diet selection, an ethnic or geographic origin selection and/or an ingredient selection; selecting a subset of food preparation methods responding to said set of selection criteria from among a stored set of food preparation methods; and presenting at least one food preparation method of said selected subset of food preparation methods. The invention also related to a learning support system for applying this method. | 02-19-2009 |
Peter Alexander Jansen, Hamilton CA
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20110056286 | DEVICE AND METHOD FOR MEASURING A QUANTITY OVER A SPATIAL REGION - The present invention enables the measurement and determination of a quantity over a selected spatial region by providing a device that incorporates a sensor for the measurement of the quantity and a spatial subsystem for determining the spatial information comprising a spatial position and/or orientation of the device when the measurement is made. A processing module integrated with the device operates on a dataset of multiple measurements correlated with spatial information and provides a determination of the quantity over the selected spatial range, either directly based on the measured data point and the spatial information or via a sensor fusion algorithm such as an interpolation algorithm. The results may be displayed on the device, for example, on a graphical display, or may be transmitted to a remote processor for subsequent processing and/or display. | 03-10-2011 |
Thomas Abraham Jansen, Rosedale CA
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20150353291 | Control System for Material Handling Conveyor Vehicle - Control solutions for a mobile conveyor vehicle are provided. The vehicle includes a pair of movable belt conveyor systems for conveying bulk material to an elevated location. One of the conveyors may be rotated via turntable while the other is rotated by four-wheel steering motion of the vehicle. The control system may be configured to: receive user input indicative of desired infeed location of the infeed end and a desired output location of the output end; determine a desired control solution for disposing the infeed end at the desired infeed location and disposing the output end at the desired output location; and cooperatively operate the first powered actuator system, the second powered actuator system and the powered drive system according to the desired control solution. | 12-10-2015 |
Wayne Benidect Jansen, Edmonton CA
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20140048451 | HIGH TEMPERATURE FROTH UNDERWASH IN AN OIL SAND BITUMEN EXTRACTION SEPARATION VESSEL - A process for enhancing the froth quality, improving vessel operability and increasing the froth temperature from an oil sand slurry in a primary separation vessel is provided, comprising introducing the oil sand slurry into a separation vessel; retaining the oil sand slurry within the separation vessel so that separate layers of bitumen froth, middlings and sand tailings are formed; introducing sufficient heated water having a temperature greater than about 80° C. as an evenly distributed underwash layer beneath the bitumen froth layer; and separately removing the bitumen froth, middlings and sand tailings from the separation vessel. | 02-20-2014 |