Patent application number | Description | Published |
20100278927 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION - The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof. | 11-04-2010 |
20100292432 | POLYMERS FOR POLYNUCLEOTIDE ENCAPSULATION - The present invention provides block copolymers comprising hydrophobic moieties in a cationic complexing block, methods of preparing the same, and intermediates thereto. The compounds are useful in a variety of applications such as the assembly of micellar polyion complexes. The invention further provides methods of using said compounds and compositions thereof. | 11-18-2010 |
20110142886 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 06-16-2011 |
20110229528 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 09-22-2011 |
20110256227 | CONTROLLED POLYPLEX ASSEMBLY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, polyplexes comprising polycations, polyanions, and polynucleotides are provided. The invention further provides methods of making and using said polyplexes. | 10-20-2011 |
20120148631 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 06-14-2012 |
20120237565 | PEGYLATED POLYPLEXES CONTAINING TWO OR MORE DIFFERENT POLYMERS FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 09-20-2012 |
20120283410 | ATTACHMENT OF BIOLOGICAL TARGETING GROUPS USING METAL FREE CLICK CHEMISTRY - The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same. | 11-08-2012 |
20130266617 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION - The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof. | 10-10-2013 |
20130344117 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 12-26-2013 |
20140302607 | POLYMER BASED POLYNUCLEOTIDE TRANSFECTION AGENTS - The present invention provides a methodology for transfecting cells in vitro. In particular, cationic polymers and polynucleotide containing polyplexes comprising such polymers are provided. | 10-09-2014 |