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Jankovic

Ivan Jankovic, Costa Mesa, CA US

Patent application numberDescriptionPublished
20110238167METHODS OF CONDITIONING SHEET BIOPROSTHETIC TISSUE - Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes. The finally thinned membrane may then be treated by capping of calcification nucleation sites and borohydride reduction. The leaflets may be formed to have more than one region of uniform thickness, such as a thicker peripheral sewing region.09-29-2011

Ivana Jankovic, Epalinges CH

Patent application numberDescriptionPublished
20100055081LONG-LASTING ABSORPTION OF FLAVONOIDS - The present invention relates to methods for a long-term and sustained release of flavonoids, in particular rhamnose-containing flavonoids, and for prolonging the uptake of said flavonoids in the gastro-intestinal tract. It further relates to compositions comprising said flavonoid and α-rhamnosidase. It also encompasses compositions comprising hesperidin and hesperetin-7-glucoside.03-04-2010

Ladislav Jankovic, Fishkill, NY US

Patent application numberDescriptionPublished
20100229650APPARATUS, SYSTEMS AND METHODS FOR PRODUCTION AND INTEGRATION OF COMPACT ILLUMINATION SCHEMES - Apparatus, systems and methods are provided for production and integration of compact illumination schemes. More particularly, disclosed embodiments relate to apparatus/systems and methods for production of highly compact illumination schemes, whereby photoacoustic waves are induced in a target sample. Additionally, the disclosed apparatus/systems and methods are effective to produce compact and portable integrated transducer-illumination arrays. Apparatus disclosed generally include at least one lighting source and a beamsplitting assembly. Systems disclosed generally include one or more apparatus for the production of compact lighting schemes, an ultrasonic transducer assembly and means for coupling the one or more apparatus and US transducer assembly with a target sample.09-16-2010
20100280504TISSUE ABLATION DEVICE WITH PHOTOACOUSTIC LESION FORMATION FEEDBACK - A tissue ablation device employs one or more energy emitters (11-04-2010

Ladislav Jankovic, Briarcliff Manor, NY US

Patent application numberDescriptionPublished
20100043557ULTRASONIC DETERMINATION OF OPTICAL ABSORPTION COEFFICIENTS - The invention relates to an examination apparatus and a method for the determination of optical coefficients, particularly of the optical absorption coefficient (μa) in an object (02-25-2010

Ladislav Jankovic, Wappingers Falls, NY US

Patent application numberDescriptionPublished
20090149761PHOTOACOUSTIC IMAGING METHOD - This invention discloses a method to position, identify and characterize a photoacoustic source in a complex environment. This method isolates individual acoustic responses from interferences by spectral analysis and filtering and locates primary acoustic sources by applying beam-forming to decomposed acoustic responses. The photon-absorbing structure of a tissue can be constructed with primary source parameters.06-11-2009

Vladimir Jankovic, New York, NY US

Patent application numberDescriptionPublished
20100124569AMNION DERIVED ADHERENT CELLS - Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such cells. Further provided herein are methods of obtaining such cells and methods of using the cells in the treatment of individuals.05-20-2010