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Janetzko

Alfred Janetzko, Butzbach/nieder-Weisel DE

Patent application numberDescriptionPublished
20100330595DIAGNOSTIC METHOD FOR DISEASES BY SCREENING FOR HEPCIDIN IN HUMAN OR ANIMAL TISSUES, BLOOD OR BODY FLUIDS AND THERAPEUTIC USES THEREFOR - The present invention concerns methods and kits for diagnosing a disease condition characterized by non-physiological levels of hepcidin, comprising obtaining a tissue or fluid sample from a subject; contacting the sample with an antibody or fragment thereof that specifically binds to a polypeptide corresponding to the mid-portion or C terminus of a hepcidin protein, and quantifying the hepcidin level using an assay based on binding of the antibody and the polypeptide; wherein the non-physiological level of hepcidin is indicative of the disease condition. The present invention also concerns diagnostic methods and kits for applications in genetic technological approaches, such as for overexpressing or downregulating hepcidin. The present invention further concerns therapeutic treatment of certain diseases by treatment of subjects with hepcidin and agonists or antagonists of hepcidin.12-30-2010

Alfred Janetzko, Butzbach DE

Patent application numberDescriptionPublished
20100086945DIAGNOSTIC METHOD FOR DISEASES BY SCREENING FOR HEPCIDIN IN HUMAN OR ANIMAL TISSUES, BLOOD OR BODY FLUIDS AND THERAPEUTIC USES THEREFOR - The present invention concerns methods and kits for diagnosing a disease condition characterized by non-physiological levels of hepcidin protein, including prohepcidin and fragments thereof, comprising obtaining a tissue or fluid sample from a subject; contacting the sample with an antibody or fragment thereof that specifically binds to a polypeptide corresponding to the amino acid sequence between and including amino acids 25 and 49 of a hepcidin precursor protein, and quantifying the hepcidin precursor level using an assay based on binding of the antibody and the polypeptide; wherein the non-physiological level of prohepcidin is indicative of the disease condition. The present invention also concerns diagnostic methods and kits for applications in genetic technological approaches, such as for overexpressing or downregulating hepcidin.04-08-2010
20110275099DIAGNOSTIC METHOD FOR DISEASES BY SCREENING FOR HEPCIDIN IN HUMAN OR ANIMAL TISSUES, BLOOD OR BODY FLUIDS AND THERAPEUTIC USES THEREFOR - The present invention concerns methods and kits for diagnosing a disease condition characterized by non-physiological levels of hepcidin protein, including prohepcidin and fragments thereof, comprising obtaining a tissue or fluid sample from a subject; contacting the sample with an antibody or fragment thereof that specifically binds to a polypeptide corresponding to the amino acid sequence between and including amino acids 25 and 49 of a hepcidin precursor protein, and quantifying the hepcidin precursor level using an assay based on binding of the antibody and the polypeptide; wherein the non-physiological level of prohepcidin is indicative of the disease condition. The present invention also concerns diagnostic methods and kits for applications in genetic technological approaches, such as for overexpressing or downregulating hepcidin.11-10-2011

Halldor Janetzko, Konstanz DE

Patent application numberDescriptionPublished
20110242106Generalized scatter plots - Color cell-based data placement systems, methods, and computer-readable storage media that visualize large amounts of multidimensional data on an output by rearranging data objects to variably grant more output space to areas with high data density and less output space to areas with low data density, and to variably rearrange overlapping data objects based on a number of data objects already placed at a preferred cell position for the data object.10-06-2011

Halldór Janetzko, Konstanz DE

Patent application numberDescriptionPublished
20110279469Performing time slice-based visual prediction - To perform time slice-based visual prediction, a weighted moving aggregate of data values in a data set is calculated over previous time slices to predict data values based on interactive user input. A visual accuracy indicator is generated for display to indicate a quality of prediction of data values at different times. A visualization presents data values from the data set and the predicted data values, where the data values from the data set and the predicted data values are represented as corresponding cells.11-17-2011