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Janes

Gregory Clayton Janes, Subiaco AU

Patent application numberDescriptionPublished
20090126082Surgical Sock - A sterile orthopaedic containment sock is described. The sock is made of a surgical polymer material, and is applied to a patient's foot prior to a surgery to isolate contaminants. The sock conforms to the patient's foot and may be packaged such that its application needs not incur contact between the patient's foot and the hand of the person applying the sock.05-21-2009

Peter Janes, Cambridge CA

Patent application numberDescriptionPublished
20100118493MOTOR DRIVE WITH HEAT PIPE AIR COOLING - An air cooled switching unit for a motor drive includes a plurality electrical switches and a plurality of heat pipe assemblies. Each heat pipe assembly includes a thermally and electrically conductive evaporator, a condenser, and at least one heat pipe extending between the evaporator and condenser. Each of the switches is abutted with an evaporator of at least one of the heat pipe assemblies for conduction of both electrical power and heat between the switch and the evaporator. Each heat pipe assembly further includes an electrically conductive base abutted with the evaporator, and the air cooled switching unit further includes a plurality of power lugs each connected to a base of a respective one of the heat pipe assemblies for input or output of electrical power to the base and the evaporator plate abutted with the base. Each heat pipe assembly includes at least one evaporator defined by a metallic plate. The condenser of each heat pipe assembly includes a plurality of parallel spaced-apart cooling fins. The at least one heat pipe of each heat pipe assembly includes a sealed pipe containing a phase-change material for transferring heat from said evaporator to said condenser. The at least one heat pipe includes a first end located in the metallic plate and a second end in contact with and extending through the cooling fins of the condenser. A temperature feedback system derives air flow velocity through the condenser.05-13-2010
20100147572Electrical Device, System and Method for Operating with Reduced Acoustic Noise Generation - Disclosed herein is a device for reducing noise generated by an electrical component, the device including a stiffening component secured to an electrical component, wherein the stiffening component provides rigidity to the electrical component, thereby reducing the mechanical resonance of the electrical component during operation. The electrical component has at least one end face and a flange portion that includes a flange face that extends about a perimeter of the end face. The flange face is substantially parallel to the end face, wherein the stiffening component is secured to the flange face of the electrical component such that it does not extend into a plane of the end face. Further, the stiffening component can include a stiffening portion and a securing portion, wherein the stiffening portion is secured to the flange face of the electrical component by the securing portion. Further, the electrical component can be a power semiconductor device.06-17-2010
20110292604AIR COOLING OF MEDIUM VOLTAGE DRIVE COMPONENTS - A parallel redundant fan system includes at least first and second fans located adjacent each other. Each fan includes: (i) a fan housing defining a fan chamber in which an impeller is supported for rotation about an axis of rotation; (ii) a first chamber outlet in communication with the fan chamber and defined by an opening in a first wall of the fan housing; (iii) a second chamber outlet in communication with the fan chamber and defined by an opening in a second wall of the fan housing; and, (iii) first and second backflow prevention dampers respectively associated with the first and second chamber outlets. The first and second dampers respectively include first and second damper plates that selectively pivot from their closed positions toward their opened positions against the closing force of respective first and second counterweights in response to exhaust air flow pressure exerted thereon.12-01-2011

Peter W. Janes, Victoria AU

Patent application numberDescriptionPublished
20080317763Regulation of Metalloprotease Cleavage of Cell Surface Proteins - Elucidation of the crystal structure of an ADAM10 substrate-recognition and proteinase-positioning module comprising the protein cysteine-rich and disintegrin domains, and detailed functional analysis revealed that an acidic pocket within the cysteine-rich domain forms a substrate-recognition site. The binding of this pocket to receptor/ligand complexes facilitates effective ligand cleavage, which is prevented when critical residues within the pocket are changed. This provides use of the surface pocket within the extracellular domain of ADAM10, and the corresponding structure in related proteases such as ADAM17, as a target for structure-based computational and high-throughput screens for small-molecule substrate-specific inhibitors or monoclonal antibodies that inhibit ADAM protease cleavage of ephrins and other ADAM10 or ADAM17 substrates. These inhibitors will be useful in therapeutic intervention of tumour development, invasion and metastasis and other diseases which involve the activity of the ADAM10 and ADAM17 proteases, such as inflammation, cardio-vascular disease, arthritis and other auto-immune diseases.12-25-2008

Sam M. Janes, London GB

Patent application numberDescriptionPublished
20120010499USE OF NANOPARTICLES FOR THE TREATMENT OF CANCER - The invention relates to the tracking of mesenchymal stem cells (MSCs) labeled with magnetic nanoparticles using magnetic resonance imaging (MRI) and the use of this method for the treatment of cancer.01-12-2012