Patent application number | Description | Published |
20090232844 | IMMUNOPOTENTIATING COMPOUNDS - The invention provides novel compositions comprising Imidazopyridine compounds. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an)other agent(s). | 09-17-2009 |
20100010217 | METHODS FOR THE PREPARATION OF IMIDAZOLE-CONTAINING COMPOUNDS - The present invention generally relates to methods for the preparation of compounds that contain imidazole moieties. In some embodiments, the methods include the reaction of a diamine with a dichloroimmonium compound to produce the imidazole moiety. In some embodiments, the methods are employed to prepare compounds having the Formulas II, II or III below: I II III wherein the constituent variables are as described herein. | 01-14-2010 |
20100130490 | CSF-1R INHIBITORS,COMPOSITIONS, AND METHODS OF USE - Benzoxazole and benzothiazole compounds and their oxides, esters, prodrugs, solvates, and pharmaceutically acceptable salts thereof are disclosed. Compositions of the compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier, and uses of the compounds, either alone or in combination with at least one additional therapeutic agent are also disclosed. The embodiments are useful for inhibiting cellular proliferation, inhibiting the growth and/or metathesis of tumors, treating or preventing cancer, treating or preventing degenerating bone diseases such as rheumatoid arthritis, and/or inhibiting molecules such as CSF 1R. | 05-27-2010 |
20100261679 | CSF-1R, Inhibitors, Compositions, and Methods of Use - Disclosed herein are compounds and their oxides, esters, prodrugs, solvates, and pharmaceutically acceptable salts thereof, compositions of the compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier, and uses of the compounds, either alone or in combination with at least one additional therapeutic agent. The embodiments are useful for inhibiting cellular proliferation, inhibiting the growth and/or metathesis of tumors, treating or preventing cancer, treating or preventing degenerating bone diseases such as rheumatoid arthritis, and/or inhibiting molecules such as CSF-1R. | 10-14-2010 |
20110028492 | Heteroaryl Compounds and Their Uses - The present invention provides a compound of formula (I): | 02-03-2011 |
20110130380 | Heteroaryl Kinase Inhibitors - The present invention provides compounds of Formula (I): | 06-02-2011 |
20120165306 | PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES - The present invention provides a compound of Formula (I): | 06-28-2012 |
20130101622 | IMIDAZOQUINOXALINE COMPOUNDS AS IMMUNOMODULATORS - The invention provides novel compositions comprising imidazoquinoxaline compounds of formula (I) and analogs thereof. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an) other agent(s). | 04-25-2013 |
20130172354 | HETEROARYL COMPOUNDS AND THEIR USES - The present invention provides a compound of formula (I): | 07-04-2013 |
20130303507 | SUBSTITUTED HETERO-BIARYL COMPOUNDS AND THEIR USES - The present invention provides a compound of formula (II): | 11-14-2013 |
20130324530 | 3-(AMINOARYL)-PYRIDINE COMPOUNDS - The present invention provides a compound of formula (I): | 12-05-2013 |
20140005070 | MARKERS ASSOCIATED WITH CYCLIN-DEPENDENT KINASE INHIBITORS | 01-02-2014 |
20140065141 | CSF-1R INHIBITORS FOR TREATMENT OF BRAIN TUMORS - The present invention provides a compound of formula I; | 03-06-2014 |
20140275083 | 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH - The invention is directed to a formula (I): | 09-18-2014 |
20140288076 | HETEROARYL COMPOUNDS AND THEIR USES - The present invention provides a compound of formula (I): | 09-25-2014 |