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James R. Ellsworth, Marshfield US

James R. Ellsworth, Marshfield, MA US

Patent application numberDescriptionPublished
20080213743Method for adjusting sedimentation rates - One or more chemicals are added to a physiological fluid to alter the density and/or shape of cells in the fluid to provide a desired sedimentation rate of the cells. In a preferred embodiment, the chemical to be added is an anticoagulant, preferably ACD.09-04-2008
20090120852Method and apparatus for separating fluid components - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed.05-14-2009
20090131877Method and apparatus for separating fluid components - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed.05-21-2009
20090283524Blood components separator disk - A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.11-19-2009
20100016830Injection of Anticoagulant Into Bone Marrow Space - A method for aspirating bone marrow includes the step of injecting anticoagulant into the area Of the bone marrow cavity surrounding the entry site of the aspiration needle. The amount of anticoagulant may be relatively small because the primary objective is to address the damage caused by entry of the needle into and through regions of the bone marrow cavity. As little as 0.5 ml heparin is injected prior to aspiration. Additional anticoagulant is provided in the collection syringe to facilitate further processing, as by centrifugal fractionation of the marrow to obtain desired components.01-21-2010
20110036786FLOATING DISK FOR SEPARATING BLOOD COMPONENTS - A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated compoments, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.02-17-2011
20110160031DECANTING CENTRIFUGE WITH VIBRATION ISOLATION - A centrifuge has a rotor for receiving a disposable processing unit. The centrifuge is configured such that the motor is attached to an enclosure and the enclosure is supported on a base. The connection between the base and the enclosure is a vibration isolator, and the isolator is positioned such that its effective line of action aligns with the effective plane of rotation of the rotor. In accordance with another feature of the invention, the processing units are held in a decanting position by a decant ring that moves vertically but does not rotate. The ring engages the top of the processing unit during decant and the abrasion is minimal.06-30-2011
20110278233FLOATING DISK FOR SEPARATING BLOOD COMPONENT - A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated components, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.11-17-2011

Patent applications by James R. Ellsworth, Marshfield, MA US