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Jain, PA

Himanshu Jain, Bethlehem, PA US

Patent application numberDescriptionPublished
20100015244Nano/Macroporous Bioactive Glasses Made by Melt-Quench Methods - The methods and materials described herein provide novel and simple procedures for the preparation of nano/macroporous glasses, in which the pore structure is characterized by interconnected pores of, e.g. both hundreds of micrometers and several to tens of nanometers in size. Such materials may be used for enhanced bone regeneration, bioscaffolds, drug delivery devices, and filtration media, among other uses. For example, silica-based bone tissue scaffolds are made with a controlled nano/macroporosity, which enhances bone regeneration performance. Also provided herein are new biocompatible CaO—Na01-21-2010
20100272826NANO/MACROPOROUS BONE TISSUE SCAFFOLDS FOR REGENERATIVE MEDICINE - A biocompatible inorganic porous material having a three-dimensional coexistent network of interconnected macro-pores and nanopores produced by the steps of mixing an organic water-soluble polymer (e.g., polyethylene oxide or a block copolymer of ethylene oxide and propylene oxide), an alkoxysilane, and an inorganic water-soluble calcium salt in an aqueous acid solution, such that a sol-gel process of hydrolysis and polycondensation is initiated and thereby producing a gel; drying the gel to remove solvent by evaporation; and heating the gel to remove the polymer by thermal decomposition, thereby forming an inorganic porous material, which may be suitable for use as a bone tissue scaffold.10-28-2010
20110057154CONDUCTIVE DOPED METAL-GLASS COMPOSITIONS AND METHODS - Provided herein are conductive glass-metal compositions, as well as methods of making and using such compositions. In one example, the compositions include gold (Au) doped lithium-borate glasses shown to exhibit a transition from ionic to electronic conduction within the same sample. This is achieved via appropriate heat treatment, and particularly by heat treatment after annealing, wherein the post-annealing heat treatment is performed at temperatures below the glass transition temperature (T03-10-2011

Nareshkumar F. Jain, Exton, PA US

Patent application numberDescriptionPublished
20080221202STEROIDS DERIVATIVES AS SELECTIVE PROGESTERONE RECEPTOR MODULATORS - The present invention is directed to novel steroid derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by at least one progesterone or glucocorticoid receptor.09-11-2008
20100069474NOVEL COUMARIN DERIVATIVES AS ION CHANNEL OPENERS - The present invention is directed to novel coumarin derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders related to ion channels such as potassium channels03-18-2010

Patent applications by Nareshkumar F. Jain, Exton, PA US

Puja Jain, Blue Bell, PA US

Patent application numberDescriptionPublished
20090214409Process for production of a borohydride compound - A process for production of a borohydride compound. The process comprises combining a compound comprising boron and oxygen with an adduct of alane.08-27-2009

Rajeev A. Jain, Norristown, PA US

Patent application numberDescriptionPublished
20080213371Rapidly disintegrating solid oral dosage form - Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, of less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity.09-04-2008
20090130213Rapidly disintegrating solid oral dosage form - Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, or less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity.05-21-2009

Surbhi Jain, Lansdale, PA US

Patent application numberDescriptionPublished
20110256538EPIGENOMIC DNA MODIFICATIONS FOR TISSUE TYPING, EARLY CANCER DETECTION, AND DISEASE MANAGEMENT - Provided herein is a suitable method for detecting the presence or absence of a cancer in an individual, by determining the level of methylation of the sense strand of a selected regulatory region of a tumor suppressor gene. Also provided herein is a method of detecting the presence or absence a cancer in an individual by determining if there is an apparent 100% methylation by assay of the CpG sites in the anti-sense strand of a selected regulatory region of a tumor suppressor gene. Also provided herein is a method of tissue typing by determining the level of methylation of the anti-sense strand of a selected regulatory region of a tumor suppressor gene indicating an enhanced likelihood that a tissue is liver.10-20-2011