Patent application number | Description | Published |
20140200246 | COMPOUNDS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH DGAT1 ACTIVITY - The present invention relates to novel crystalline forms of salts of 2-((1R,4R)-4-(4-(5-(benzo[d]oxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans. | 07-17-2014 |
20140275001 | CRYSTALLINE FORM OF A BETA-LACTAMASE INHIBITOR - This disclosure provides compositions containing solid forms of sodium (2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate, and methods of manufacturing and using these compositions. | 09-18-2014 |
20150111864 | CRYSTALLINE FORM OF A BETA-LACTAMASE INHIBITOR - This disclosure provides compositions containing solid forms of (2S,5R)-2-(5-(3-aminopropyl)-1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate, and methods of manufacturing and using these compositions. | 04-23-2015 |
20150316568 | Method for Screening Lyophilized Parenteral Formulations - Embodiments of the present invention feature methods for screening parenteral formulations which require small quantities of drug and rapid results. The method features steps of identifying one or more solutions for reconstitution and applying the solutions to lyophilized drug, excipient and diluent combinations. | 11-05-2015 |
Patent application number | Description | Published |
20130140518 | QUANTUM DOT GATE FETS AND CIRCUITS CONFIGURED AS BIOSENSORS AND GENE SEQUENCERS - Quantum dot (QD) gate FETs and the use of quantum dot (QD) gate FETs for the purpose of sensing analytes and proteins is disclosed and described. Analytes, proteins, miRNAs, and DNAs functionalized to the QDs change the charge density in the gate and hence the current-voltage characteristics. In one embodiment, QD-FETs, such as | 06-06-2013 |
20130172846 | DEVICES, SYSTEMS, AND METHODS FOR EXCAVATING CANCER CELLS - Methods, devices, and systems are provided for guiding tumor movement, particularly in vivo for treatment of patients. The method may include implanting into a tissue site where tumor cells are present a device having one or more surface structures or substrates, such as aligned nanofibers, which provide physical guidance cues for directing the migration of the tumor cells from the first tissue location to a selected second location, for tumor cell extraction or death. The devices and systems may include a cytotoxic agent for contacting tumor cells migrated via the substrate. All or a portion of the at least one substrate may include one or more biochemical cues, such as a coating of laminin or another protein, which may be provided in a concentration gradient to facilitate uni-directional tumor cell migration. | 07-04-2013 |
Patent application number | Description | Published |
20120037844 | MIXED PHOSPHATE-DIPHOSPHATE ELECTRODE MATERIALS AND METHODS OF MANUFACTURING SAME - This invention relates generally to electrode materials, electrochemical cells employing such materials, and methods of synthesizing such materials. The electrode materials have a crystal structure with a high ratio of Li to metal M, which is found to improve capacity by enabling the transfer of a greater amount of lithium per metal, and which is also found to improve stability by retaining a sufficient amount of lithium after charging. Furthermore, synthesis techniques are presented which result in improved charge and discharge capacities and reduced particle sizes of the electrode materials. | 02-16-2012 |
20130089486 | CARBOPHOSPHATES AND RELATED COMPOUNDS - The present invention generally relates to carbophosphates and other compounds. Such compounds may be used in batteries and other electrochemical devices, or in other applications such as those described herein. One aspect of the invention is generally directed to carbophosphate compounds, i.e., compounds containing carbonate and phosphate ions. For example, according to one set of embodiments, the compound has a formula A | 04-11-2013 |
20130273425 | MIXED PHOSPHATE-DIPHOSPHATE ELECTRODE MATERIALS AND METHODS OF MANUFACTURING SAME - This invention relates generally to electrode materials, electrochemical cells employing such materials, and methods of synthesizing such materials. The electrode materials have a crystal structure with a high ratio of Li to metal M, which is found to improve capacity by enabling the transfer of a greater amount of lithium per metal, and which is also found to improve stability by retaining a sufficient amount of lithium after charging. Furthermore, synthesis techniques are presented which result in improved charge and discharge capacities and reduced particle sizes of the electrode materials. | 10-17-2013 |
Patent application number | Description | Published |
20140013675 | Abrasive Article and Method Of Forming - An abrasive article including a substrate having an elongated body, a tacking layer overlying the substrate, and a first type of abrasive particle overlying the tacking layer and defining a first abrasive particle concentration at least about 10 particles per mm of substrate. | 01-16-2014 |
20140150766 | ABRASIVE ARTICLE AND METHOD OF FORMING - A method of conducting a cutting operation on a workpiece including providing an abrasive article having a substrate having an elongated body, a tacking layer overlying the substrate, and a first type of abrasive particle contained in the tacking layer, the method further including moving the abrasive article and a workpiece relative to each other, the workpiece including a material selected from the group consisting of a ceramic, a semiconductive material, an insulating material, a glass, a natural material, organic material, and a combination thereof. | 06-05-2014 |
Patent application number | Description | Published |
20100062066 | Formulations of Tetrahydropyridine Antiplatelet Agents for Parenteral or Oral Administration - A pharmaceutical composition for the oral or parenteral administration of a compound of Formula (I) comprising an oil in water emulsion, wherein the oil phase comprises the free base of or a pharmaceutically acceptable salt thereof of a compound of Formula (I), and one or more surfactants which are soluble in the oil phase and/or the aqueous phase. The emulsion optionally contains one or more excipients that are soluble in the oil phase and/or the aqueous phase, such as pH modifying agents such as buffers, osmolality/tonicity modifying agents, emulsifying agents, water-soluble polymers, and preservatives. The compound of Formula (I) can be formulated as a solid material and stored until needed. Kits for forming the emulsion are provided. Prior to administration, the solid material can be reconstituted in an aqueous medium to form the emulsion. | 03-11-2010 |
20110300210 | CONTROLLED RELEASE NANOPARTICULATE CLOZAPINE COMPOSITIONS - Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer. | 12-08-2011 |
20120114754 | RAPIDLY DISINTEGRATING SOLID ORAL DOSAGE FORM - Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water-dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, of less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity. | 05-10-2012 |
20130011447 | CONTROLLED RELEASE NANOPARTICULATE COMPOSITIONS - Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer. | 01-10-2013 |
Patent application number | Description | Published |
20090298081 | METHODS OF TREATMENT UTILIZING BINDING PROTEINS OF THE INTERLEUKIN-21 RECEPTOR - The present invention provides binding proteins and antigen-binding fragments thereof, including human antibodies, that specifically bind to the human interleukin-21 receptor (IL-21R), and methods of using them. The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing, treating, and/or preventing IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, and other immune system disorders. | 12-03-2009 |
20120276102 | METHODS OF TREATMENT UTILIZIING BINDING PROTEINS OF THE INTERLEUKIN-21 RECEPTOR - The present invention provides binding proteins and antigen-binding fragments thereof, including human antibodies, that specifically bind to the human interleukin-21 receptor (IL-21R), and methods of using them. The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing, treating, and/or preventing IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, and other immune system disorders. | 11-01-2012 |
Patent application number | Description | Published |
20100161608 | METHODS AND APPARATUS FOR CONTENT-AWARE DATA DE-DUPLICATION - The systems and methods partition digital data units in a content aware fashion without relying on any ancestry information, which enables one to find duplicate chunks in unrelated units of digital data even across millions of documents spread across thousands of computer systems. | 06-24-2010 |
20100161685 | METHODS AND APPARATUS FOR CONTENT-AWARE DATA PARTITIONING - The systems and methods partition digital data units in a content aware fashion without relying on any ancestry information, which enables one to find duplicate chunks in unrelated units of digital data even across millions of documents spread across thousands of computer systems. | 06-24-2010 |
20110225141 | Distributed Catalog, Data Store, and Indexing - This disclosure relates to a system and method for distributed catalog processing, data caching, and indexing to create an efficient, scalable, secure, high availability, disaster recovery enabled backup and storage system. | 09-15-2011 |
20110231374 | Highly Scalable and Distributed Data De-Duplication - This disclosure relates to systems and methods for both maintaining referential integrity within a data storage system, and freeing unused storage in the system, without the need to maintain reference counts to the blocks of storage used to represent and store the data. | 09-22-2011 |
20130232126 | HIGHLY SCALABLE AND DISTRIBUTED DATA DE-DUPLICATION - This disclosure relates to systems and methods for both maintaining referential integrity within a data storage system, and freeing unused storage in the system, without the need to maintain reference counts to the blocks of storage used to represent and store the data. | 09-05-2013 |
Patent application number | Description | Published |
20140080058 | ACID GENERATORS AND PHOTORESISTS COMPRISING SAME - Acid generator compounds are provided that are particularly useful as photoresist composition components. Preferred acid generators include cyclic sulfonium compounds that comprise a covalently linked acid-labile group. | 03-20-2014 |
20140080059 | ACID GENERATOR COMPOUNDS AND PHOTORESISTS COMPRISING SAME - Acid generator compounds are provided that are particularly useful as a photoresist composition component. Acid generator compounds of the invention comprise 1) a cyclic sulfonium salt and 2) a covalently linked photoacid-labile group. In one aspect, thioxanthone acid generator compounds are particularly preferred, including acid generator compounds that comprise (i) a thioxanthone moiety; and (ii) one or more covalently linked acid labile-groups. | 03-20-2014 |
20140080062 | PHOTORESISTS COMPRISING MULTIPLE ACID GENERATOR COMPOUNDS - The present invention relates to new photoresist compositions that comprise (a) a polymer comprising an acid generator bonded thereto; and (b) an acid generator compound that is not bonded to the polymer and that comprises one or more acid-labile groups. | 03-20-2014 |
20150177613 | PHOTOACID-GENERATING COPOLYMER AND ASSOCIATED PHOTORESIST COMPOSITION, COATED SUBSTRATE, AND METHOD OF FORMING AN ELECTRONIC DEVICE - A copolymer include repeat units derived from an acid-labile monomer, an aliphatic lactone-containing monomer, a C | 06-25-2015 |
20150177614 | COPOLYMER WITH ACID-LABILE GROUP, PHOTORESIST COMPOSITION, COATED SUBSTRATE, AND METHOD OF FORMING AN ELECTRONIC DEVICE - A copolymer includes repeat units derived from a lactone-substituted monomer, a base-soluble monomer having a pK | 06-25-2015 |
20150177615 | PHOTOACID-GENERATING COPOLYMER AND ASSOCIATED PHOTORESIST COMPOSITION, COATED SUBSTRATE, AND METHOD OF FORMING AN ELECTRONIC DEVICE - A copolymer include repeat units derived from an acid-labile monomer, an aliphatic lactone-containing monomer, a C | 06-25-2015 |
20160002199 | ACID GENERATORS AND PHOTORESISTS COMPRISING SAME - Acid generator compounds are provided that are particularly useful as photoresist composition components. Preferred acid generators include cyclic sulfonium compounds that comprise a covalently linked acid-labile group. | 01-07-2016 |
20160102157 | POLYMER COMPRISING REPEAT UNITS WITH PHOTOACID-GENERATING FUNCTIONALITY AND BASE-SOLUBILITY-ENHANCING FUNCTIONALITY, AND ASSOCIATED PHOTORESIST COMPOSITION AND ELECTRONIC DEVICE FORMING METHOD - A polymer includes repeat units, at least half of which are photoacid-generating repeat units. Each of the photoacid-generating repeat units includes photoacid-generating functionality and base-solubility-enhancing functionality. The polymer is useful as a component of a photoresist composition that further includes a second polymer that exhibits a change in solubility in an alkali developer under action of acid. | 04-14-2016 |
20160102158 | POLYMER COMPRISING REPEAT UNITS WITH PHOTOACID-GENERATING FUNCTIONALITY AND BASE-SOLUBILITY-ENHANCING FUNCTIONALITY, AND ASSOCIATED PHOTORESIST COMPOSITION AND ELECTRONIC DEVICE FORMING METHOD - A polymer includes repeat units, most of which are photoacid-generating repeat units. Each of the photoacid-generating repeat units includes photoacid-generating functionality and base-solubility-enhancing functionality. Each of the photoacid-generating repeat units comprises an anion and a photoacid-generating cation that collectively have structure (I) | 04-14-2016 |
20160103391 | PHOTORESIST COMPOSITION AND ASSOCIATED METHOD OF FORMING AN ELECTRONIC DEVICE - A photoresist composition includes a first polymer in which at least half of the repeat units are photoacid-generating repeat units, and a second polymer that exhibits a change in solubility in an alkali developer under the action of acid. In the first polymer, each of the photoacid-generating repeat units comprises photoacid-generating functionality and base-solubility-enhancing functionality. | 04-14-2016 |
20160103392 | PHOTORESIST COMPOSITION AND ASSOCIATED METHOD OF FORMING AN ELECTRONIC DEVICE - A photoresist composition includes a first polymer in which at least half of the repeat units are photoacid-generating repeat units, and a second polymer that exhibits a change in solubility in an alkali developer under the action of acid. In the first polymer, each of the photoacid-generating repeat units comprises photoacid-generating functionality and base-solubility-enhancing functionality. | 04-14-2016 |
Patent application number | Description | Published |
20110033800 | COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST - Cyanurate compositions are provided that are particularly useful as a reagent to form a resin component of a coating composition underlying an overcoated photoresist. Preferred isocyanurates compound comprise substitution of multiple cyanurate nitrogen ring atoms by at least two distinct carboxy and/or carboxy ester groups. | 02-10-2011 |
20110033801 | COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST - Coating compositions for use with an overcoated photoresist are provided where the coating composition comprises a resin containing cyanurate groups and hydrophobic groups. The coating composition can enhance resolution of an overcoated photoresist relief image. | 02-10-2011 |
20120141939 | PHOTOACID GENERATORS - A photoacid generator compound has formula (I): | 06-07-2012 |
20120171616 | POLYMERIZABLE PHOTOACID GENERATORS - A compound has formula (I): | 07-05-2012 |
20130004893 | COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST - Organic coating compositions, particularly antireflective coating compositions, are provided that comprise that comprise a component that comprises one or more parabanic acid moieties. Preferred compositions of the invention are useful to reduce reflection of exposing radiation from a substrate back into an overcoated photoresist layer and/or function as a planarizing, conformal or via-fill layer. | 01-03-2013 |
20130004901 | COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST - Organic coating compositions, particularly antireflective coating compositions, are provided that comprise that comprise a component that comprises one or more uracil moieties. Preferred compositions of the invention are useful to reduce reflection of exposing radiation from a substrate back into an overcoated photoresist layer and/or function as a planarizing, conformal or via-fill layer. | 01-03-2013 |
20130078569 | CALIXARENE AND PHOTORESIST COMPOSITION COMPRISING SAME - A molecular glass compound comprises a vinyl ether adduct of an aromatic vinyl ether of formula C(R | 03-28-2013 |
20130157195 | CALIXARENE COMPOUND AND PHOTORESIST COMPOSITION COMPRISING SAME - A molecular glass compound includes (A) a tetrameric reaction product of a specific aromatic compound having at least one hydroxy group, and a specific polycyclic or fused polycyclic aromatic aldehyde; and (B) an acid-removable protecting group as an adduct with the hydroxy group of the aromatic compound and/or a hydroxy group of the polycyclic or fused polycyclic aromatic aldehyde. A photoresist composition including the molecular glass compound, and a coated substrate including a layer of the photoresist composition are also disclosed. | 06-20-2013 |
20140030653 | COATING COMPOSITIONS FOR PHOTOLITHOGRAPHY - Underlying coating compositions are provided that comprise one or more resins comprising one or more modified imide groups. These coating compositions are particularly useful as antireflective layers for an overcoated photoresist layer. Preferred systems can be thermally treated to increase hydrophilicity of the composition coating layer to inhibit undesired intermixing with an overcoated organic composition layer, while rendering the composition coating layer removable with aqueous alkaline photoresist developer. | 01-30-2014 |
20150021289 | PHOTORESIST COMPOSITION, COATED SUBSTRATE, AND METHOD OF FORMING ELECTRONIC DEVICE - A photoresist composition includes a polymer with repeat units having the structure | 01-22-2015 |