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Jahangir, US

Alam Jahangir, San Jose, CA US

Patent application numberDescriptionPublished
20080207619Diaminopyrimidines as P2X3 and P2X2/3 modulators - Compounds and methods for treating diseases mediated by a P2X08-28-2008
20080207655Diaminopyrimidines as P2X3 and P2X2/3 modulators - Compounds of formula (I):08-28-2008
20090318484Inhibitors of JNK - The invention relates to prodrugs of JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses prodrugs of JNK inhibitors, as described below in formula I:12-24-2009
20100160360JNK MODULATORS - Compounds of formula I modulate JNK:06-24-2010
20100267666Pyrrolopyrazine kinase inhibitors - The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I,10-21-2010
20110071179MACROCYCLIC INHIBITORS OF JAK - The present invention relates to the use of novel macrocyclic compounds of Formula I,03-24-2011
20110077242DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS - Compounds and methods for treating diseases mediated by a P2X03-31-2011

Patent applications by Alam Jahangir, San Jose, CA US

Arshad Jahangir, Scottsdale, AZ US

Patent application numberDescriptionPublished
20090187187Controlling Coagulum Formation - Some embodiments of a medical instrument can be configured to reduce the formation of coagulum by delivering a negative charge bias to conductive surfaces that interface with blood or bodily tissue during a medical procedure. The application of the negative charge at the instrument-blood interface can reduce the fibrinogen deposition and the formation of coagulum because fibrinogen molecules in general are negatively charged at neutral pH levels. In addition, some embodiments of the instrument may be configured to irrigate the instrument-blood interface with RGD/ClfA peptides, a bicarbonate solution (or other high pH solution), or both to further repel the fibrinogen and thereby inhibit the formation of coagulum. Accordingly, some embodiments of the medical instrument can substantially reduce the risks of thromboembolism during particular medical procedures.07-23-2009