| 20090311141 | IMMUNOCHROMATOGRAPHIC STRIP FOR USE IN IMMUNOASSAY AND KIT COMPRISING THE SAME - The present invention relates to an immunochromatographic strip and a kit comprising the same. The immunochromatographic strip according to the present invention is characterized in that it comprises a) an adhesive plastic backing, b) a sample pad receiving a liquid sample to be analyzed, which is attached on the surface of the top portion of the adhesive plastic backing, a conjugate pad coupled to the sample pad, which contains a conjugate specifically binding to an analyte in the liquid sample from the sample pad, d) a signal detection pad coupled to the conjugate pad, which comprises a signal detection zone to detect the presence of the analyte in the liquid sample and a control zone to confirm whether the liquid sample chromatographically migrates regardless of the presence of the analyte, and e) an absorbent pad positioned downstream of the signal detection pad, which absorbs the liquid sample after the completion of the signal detection reaction and comprises a porous backing and an absorbent dispersed, adsorbed, or coated into the pores of the porous backing. It is more preferable that the absorbent pad further comprises a film layer attached on the top portion of the porous backing. It is most preferable that the film layer attached on the top portion of the porous backing is a porous membrane. The absorbent pad having the above-described structure efficiently absorbs the liquid sample after the completion of the signal detection reaction. As a result, the chromatographic flow is improved, test errors caused by the backflow of liquid sample are reduced, background clearance is improved, and the result of signal detection is consistently maintained. More significantly, with the help of the absorption ability improved by the absorbent which is dispersed into the porous backing, more preferably adsorbed, or coated onto fibers of the porous backing, the immunochromatographic strip and kit comprising the same absorb moisture in air quickly and sufficiently. Thus, in addition to improved performance, there is no need to package the strip or the kit with an additional absorbent bag in a pouch, which makes the packaging process simple, thereby improving the speed of automatic packaging process. | 12-17-2009 |
