Patent application number | Description | Published |
20090317478 | METHOD OF PREPARING COVERED POROUS BIODEGRADABLE POLYMER MICROSPHERES FOR SUSTAINED-RELEASE DRUG DELIVERY AND TISSUE REGENERATION - The present invention relates to covered porous biodegradable polymer microspheres for sustained-release drug delivery and tissue regeneration which has an interconnected inner open pore structure having a wide surface area and high porosity and an outer closed pore structure in which the surface of the microsphere is covered with a thin layer of a biodegradable polymer, and thereby the pores formed on the surface and exposed to the outside are closed; and methods for preparing the same. Due to such a characteristic pore structure, the covered porous biodegradable polymer microspheres according to the present invention can prevent the biologically active material from being excessively released in the early stage immediately after administration, and after that, can gradually release the biologically active material through the interconnected inner pore structure over a prolonged period as the biodegradable polymer thin layer is degraded. Therefore, the microsphere of the present invention can be effectively used for sustained-release drug delivery and tissue regeneration. | 12-24-2009 |
20100055396 | METHOD FOR HIGH RESOLUTION INK-JET PRINT USING PRE-PATTERNED SUBSTRATE AND CONDUCTIVE SUBSTRATE MANUFACTURED USING THE SAME - A method for high resolution ink-jet print using a pre-patterned substrate employs an ink-jet printing device including an ink-jet head for discharging conductive ink droplets and a driving stage for supporting a substrate to which the conductive ink droplets are hit, to draw a fine line width pattern on the substrate. The method includes (A) forming a stripe pattern with repeated stripes on a substrate surface on which a fine line width pattern will be formed, thereby preparing a pre-patterned substrate; (B) loading the substrate to the ink-jet printing device; and (C) injecting conductive ink droplets to a substrate region where the stripe pattern is formed. An equivalent interval (d) of the stripe pattern and a fine line width (D) of the drawn fine line width pattern satisfy a relation of d<03-04-2010 | |
20100098762 | Thermosensitive Pluronic Derivative Hydrogels With High Biodegradability And Biocompatibility For Tissue Regeneration And Preparation Method Thereof - The present invention relates to a thermosensitive pluronic derivative hydrogel for tissue regeneration in which a biodegradable polymer is introduced at one end or both ends of a pluronic polymer, a methacryloxyethyl trimellitic acid anhydride is conjugated to the biodegradable polymer, and a physiologically active substance is fixed to the methacryloxyethyl trimellitic acid anhydride, as well as a method for the preparation thereof. The pluronic derivative hydrogel according to the present invention exhibits high biodegradability due to the introduction of a biodegradable polymer while still maintaining the themosensitivity of the pluronic polymer itself and shows good biocompatibility owing to the coupling with a physiologically active substance capable of improving cell adhesion, proliferation and differentiation. Therefore, the pluronic derivative hydrogel according to the present invention can be effectively used in the regeneration of various kinds of tissues and organs. | 04-22-2010 |
20100129422 | POROUS BIODEGRADABLE POLYMER SCAFFOLDS FOR IN SITU TISSUE REGENERATION AND METHOD FOR THE PREPARATION THEREOF - The present invention relates to an intelligent porous biodegradable polymer scaffold for in situ tissue regeneration in which two kinds of physiologically active substances having high differentiation potential and biocompatibility are introduced into the polymer scaffold and conjugated to the surface thereof, respectively, and a method for the preparation thereof. Since the intelligent porous biodegradable polymer scaffold exhibits improved biocompatibility and differentiation potential due to the introduction of physiologically active substances capable of efficiently inducing cell proliferation and differentiation into both the surface and the inside thereof, it can directly induce in situ tissue regeneration of the musculoskeletal system from stem cells in a living tissue after transplanting the polymer scaffold and stem cells into a human body without additional in vitro cultivation. Therefore, the intelligent porous biodegradable polymer scaffold according to the present invention can be effectively used in the regeneration of various kinds of tissues and organs including the musculoskeletal system. | 05-27-2010 |
20100172262 | APPARATUS AND METHOD FOR DELAY TIME COMPUTATION AND DELAY COMPENSATION BETWEEN BASE STATION AND REMOTE RADIO FREQUENCY UNIT IN BROADBAND WIRELESS ACCESS SYSTEM - An apparatus and method for delay time computation and delay compensation between a Base Station (BS) and a remote Radio Frequency (RF) unit in a broadband wireless access system are provided. In a method of operating an apparatus for determining a delay time to compensate for delay between a BS modem card and a remote RF unit in a wireless access system, the method includes determining a process delay time required when traffic data is output from the BS modem card to an antenna of the remote RF unit in a state where a reference cable having a length short enough to neglect a cable delay time is connected between the BS modem card and the remote RF unit, determining a cable delay time required when a sync pulse signal is transmitted through a cable used in actual system operation between the BS modem card and the remote RF unit, and determining a time for outputting traffic data at an earlier time from a modem included in the BS modem card by using the determined process delay time and cable delay time. | 07-08-2010 |
20100279233 | METHOD FOR LASER INTERFERENCE LITHOGRAPHY USING DIFFRACTION GRATING - A method for laser interference lithography using a diffraction grating includes (a) forming a photoresist layer on a work substrate to which a repeated fine pattern is to be formed; (b) forming a refractive index matching material layer on the photoresist layer; (c) forming on the refractive index matching material layer a diffraction grating layer having a period of diffraction grating within the range from λ/n | 11-04-2010 |
20110111367 | NANOCOUPLING FOR IMPROVEMENT OF COATING ADHESION OF POLYMER ON METAL SUBSTRATES - Disclosed is nanocoupling of a polymer onto a surface of a metal substrate for improving coating adhesion of the polymer on the metal substrate, and in vivo stability and durability of the polymer. In accordance with the present invention, the polymers can be grafted via a chemical bonding on the surface of the metal substrate by the nanocoupling, by which adhesion, biocompatibility and durability of a polymer-coated layer which is to be formed later on the metal substrate were remarkably improved; therefore, the nanocoupling according to the present invention can be applied to surface modification of a metal implant, such as stents, mechanical valves, and an articular, a spinal, a dental and an orthopedic implants. | 05-12-2011 |
20110263018 | CORE-SHELL STRUCTURED DELIVERY SYSTEM FOR GROWTH FACTORS, A PREPARATION METHOD THEREOF, AND USE THEREOF FOR THE DIFFERENTIATION OR PROLIFERATION OF CELLS - The present invention relates to a method of preparing a delivery system capable of loading bioactive growth factors that are essential for the differentiation and proliferation of cells and is characterized as loading at least two types of components comprising growth factors in a single carrier, whereby the release of each of the plurality of growth factors can be temporally controlled. Specifically, the method of preparing a microcapsule type growth factor delivery system according to the present invention includes: (1) preparing a polymeric microsphere comprising a first component, and then encapsulating the microspheres by electrodropping the polymer microsphere into another polymer comprising a second component, thereby manufacturing a core-shell structured, microcapsule type delivery system, or (2) encapsulating a polymer solution comprising a first component by electrodropping the polymer solution into another polymer comprising a second component, thereby manufacturing a core-shell structured microcapsule type delivery system. The present invention also provides a stem cell differentiation method involving bringing a microcapsule type delivery system loaded with multiple growth factors according to the present invention into contact with stem cells. | 10-27-2011 |
20120183741 | METHOD FOR HIGH RRESOLUTION INK-JET PRINT USING PRE-PATTERNED SUBSTRATE AND CONDUCTIVE SUBSTRATE MANUFACTURED USING THE SAME - A method for high resolution ink-jet print using a pre-patterned substrate employs an ink-jet printing device including an ink-jet head for discharging conductive ink droplets and a driving stage for supporting a substrate to which the conductive ink droplets are hit, to draw a fine line width pattern on the substrate. The method includes (A) forming a stripe pattern with repeated stripes on a substrate surface on which a fine line width pattern will be formed, thereby preparing a pre-patterned substrate; (B) loading the substrate to the ink-jet printing device; and (C) injecting conductive ink droplets to a substrate region where the stripe pattern is formed. An equivalent interval (d) of the stripe pattern and a fine line width (D) of the drawn fine line width pattern satisfy a relation of d<07-19-2012 | |
20120212816 | SUBSTRATE HAVING LOW REFLECTION AND HIGH CONTACT ANGLE, AND PRODUCTION METHOD FOR SAME - Provided are a substrate including a base with a pattern on at least one side thereof, in which a refractive index in a lower region of the pattern and a refractive index in an upper region of the pattern are different from each other according to a shape of the pattern; and a water repellent coating layer provided on at least one side with the pattern of the base, an optical product including the same, and a manufacturing method of the substrate. The substrate according to the present invention has both an excellent anti-reflective property and an excellent water repellent property. | 08-23-2012 |
20120300475 | LIGHTING DEVICE - A lighting device may be provided that includes: a light emitting module; a heat sink disposed on the light emitting module; a heat radiating fan disposed on the heat sink; and a housing which receives the light emitting module, the heat sink and the heat radiating fan, and includes an air inlet port and an air outlet port which are separated from each other, and includes a partition separating the air inlet port from the air outlet port, wherein the air inlet port is connected to a space between the heat radiating fan and the housing, and wherein the air outlet port is connected to a space between the heat sink and the heat radiating fan. | 11-29-2012 |
20130039072 | LIGHTING DEVICE - A lighting device may be provided that includes: a housing having a top opening and a bottom opening; an optical plate disposed in the top opening; heat sink disposed in the bottom opening; a driving unit which is received in the housing, disposed between the optical plate and the heat sink and receives external electric power; and light source which is received in the housing, disposed between the optical plate and the driving unit, spatially separated from the driving unit and is electrically connected to the driving unit. | 02-14-2013 |
20140240994 | LIGHTING DEVICE - A lighting device includes a heat sink including a first heat radiation part and a second heat radiation part; a light source module including a substrate disposed on the first heat radiation part, and a light emitting device disposed on the substrate; and a power supply unit which is disposed within the second heat radiation part and supplies power to the light source module. The second heat radiation part includes an inner portion receiving the power supply unit therewithin, an outer portion enclosing the inner portion, and a first receiver disposed between the inner portion and the outer portion. The first heat radiation part includes an upper portion which is disposed on the inner portion of the second heat radiation part and on which the substrate of the light source module is disposed, and a lower portion disposed in the first receiver of the second heat radiation part. | 08-28-2014 |
20140327420 | POWER SUPPLY AND DC-DC CONVERTER THEREIN - A power supply includes a rectifier circuit to rectify power, a smoothing circuit unit to smoothen a voltage of the rectified power, and a voltage drop circuit unit to drop the smoothened voltage. The voltage drop circuit unit includes an electric charge storage circuit to output the voltage-dropped voltage, a resonance circuit to receive first current from the smoothing circuit unit and to supply second current to the electric charge storage circuit, and a current interruption circuit to control the first current and the second current using zero current switching for performing switching when current does not flow using a resonance circuit. | 11-06-2014 |