| Patent application number | Description | Published |
|---|
| 20080233557 | PNA Probes, Kits, and Methods for Detecting Lamivudine-Resistant Hepatitis B Viruses - Disclosed are peptide nucleic acid (PNA) probes to detect lamivudine resistant mutants of hepatitis B virus (HBV), which causes acute and chronic hepatitis, kits for detecting lamivudine resistant HBV comprising the PNA probes, and methods for detecting lamivudine resistant HBV by using the kits. They can accurately detect mutations of rtL180M, rtM204V, rtM204I and rtV2071 within B and C domains of HBV DNA polymerase gene, the main cause of lamivudine resistance, as well as mixed mutants of more than one mutant. They can detect lamivudine resistant HBV with high specificity and sensitivity. | 09-25-2008 |
| 20080248461 | PNA Probes, Kits, and Methods for Detecting Genotypes of Human Papillomavirus - Disclosed are PNA probes capable of genotype specifically binding with Human Paillomavirus (HPV) DNA, kits for detecting HPV genotypes comprising the probes, and methods for detecting HPV genotypes by using the kits, which enables the accurate detection of all 24 genotypes of HPV found in cervix, diagnosis of combined infection with more than one HPV genotype, and detection of HPV genotypes with high specificity and sensitivity. | 10-09-2008 |
| 20090312197 | PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME - The present invention relates to a peptide nucleic acid (PNA) conjugated with multi-amine linkers, and a method to prepare the same and utilization thereof. More specifically, the method is characterized by conjugating monomers having multi-amine functionality sequentially at a PNA terminal, and effectively immobilizing the PNA conjugated with multi-amine linkers on a solid surface. A PNA array prepared using the PNA conjugated with multi-amine linkers exhibits improved sensitivity and specificity of signals for detecting target nucleic acids as compared to a PNA array using PNA probes having only one amine group. The PNA conjugated with multi-amine linkers can be utilized in nucleic acid detecting devices or kits for gene diagnosis such as PNA microarrays, PNA chips, PNA field-effect transistors and impedance detectors. | 12-17-2009 |
| 20100248980 | Method for Selective Labeling and Detection of Target Nucleic Acids Using Immobilized Peptide Nucleic Acid Probes - Disclosed are a method for selective labeling of target nucleic acids on an array having nucleic acid analogue, e.g. PNA (peptide nucleic acid), probes immobilized on a support or supports, comprising adding to the array a detectable label and an agent for introducing the label into the target nucleic acids, after hybridization between the target nucleic acids and the nucleic acid analogue probes, and a method for detection of target nucleic acids using the same. | 09-30-2010 |
| 20100292471 | PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME - Disclosed is a PNA oligomer with increased solubility in water and specificity upon hybridization with nucleic acid, which comprises at least one universal base, capable of forming a base pair with natural DNA or RNA bases, incorporated in its base sequence, the base sequence having at least 60% purine bases or at least four contiguous purine bases. | 11-18-2010 |
| 20110111416 | Peptide Nucleic Acid Probes, Kits and Methods for Expression Profiling of Micrornas - Disclosed are peptide nucleic acid (PNA) probes, a kit and a method for expression profiling of microRNAs (miRNAs), which play an important role in regulation of expression of genes encoding proteins. | 05-12-2011 |
| Patent application number | Description | Published |
|---|
| 20080241661 | Mobile terminal with user identification card including personal finance-related information and method of using a value-added mobile service through said mobile terminal - The present invention enables a user to receive a financial service anywhere through a mobile terminal equipped with a UIM (User Identification Module) electronic card. In the present invention, a user enters his or her password to a mobile terminal with a UIM card including subscriber telephone number, finance, authorization, and personal information, then, if the entered password is correct, authorization is processed with a remote authorizing server based on the authorization information. After authorization, user's requesting service, e.g., payment service, transaction particulars inquiry service, prepaid card recharging service is conducted through a mobile network. | 10-02-2008 |
| 20080242355 | Mobile terminal with user identification card including personal finance-related information and method of using a value-added mobile service through said mobile terminal - The present invention enables a user to receive a financial service anywhere through a mobile terminal equipped with a UIM (User Identification Module) electronic card. In the present invention, a user enters his or her password to a mobile terminal with a UIM card including subscriber telephone number, finance, authorization, and personal information, then, if the entered password is correct, authorization is processed with a remote authorizing server based on the authorization information. After authorization, user's requesting service, e.g., payment service, transaction particulars inquiry service, prepaid card recharging service is conducted through a mobile network. | 10-02-2008 |
| Patent application number | Description | Published |
|---|
| 20090317478 | METHOD OF PREPARING COVERED POROUS BIODEGRADABLE POLYMER MICROSPHERES FOR SUSTAINED-RELEASE DRUG DELIVERY AND TISSUE REGENERATION - The present invention relates to covered porous biodegradable polymer microspheres for sustained-release drug delivery and tissue regeneration which has an interconnected inner open pore structure having a wide surface area and high porosity and an outer closed pore structure in which the surface of the microsphere is covered with a thin layer of a biodegradable polymer, and thereby the pores formed on the surface and exposed to the outside are closed; and methods for preparing the same. Due to such a characteristic pore structure, the covered porous biodegradable polymer microspheres according to the present invention can prevent the biologically active material from being excessively released in the early stage immediately after administration, and after that, can gradually release the biologically active material through the interconnected inner pore structure over a prolonged period as the biodegradable polymer thin layer is degraded. Therefore, the microsphere of the present invention can be effectively used for sustained-release drug delivery and tissue regeneration. | 12-24-2009 |
| 20100055396 | METHOD FOR HIGH RESOLUTION INK-JET PRINT USING PRE-PATTERNED SUBSTRATE AND CONDUCTIVE SUBSTRATE MANUFACTURED USING THE SAME - A method for high resolution ink-jet print using a pre-patterned substrate employs an ink-jet printing device including an ink-jet head for discharging conductive ink droplets and a driving stage for supporting a substrate to which the conductive ink droplets are hit, to draw a fine line width pattern on the substrate. The method includes (A) forming a stripe pattern with repeated stripes on a substrate surface on which a fine line width pattern will be formed, thereby preparing a pre-patterned substrate; (B) loading the substrate to the ink-jet printing device; and (C) injecting conductive ink droplets to a substrate region where the stripe pattern is formed. An equivalent interval (d) of the stripe pattern and a fine line width (D) of the drawn fine line width pattern satisfy a relation of d<| 03-04-2010 | |
| 20100098762 | Thermosensitive Pluronic Derivative Hydrogels With High Biodegradability And Biocompatibility For Tissue Regeneration And Preparation Method Thereof - The present invention relates to a thermosensitive pluronic derivative hydrogel for tissue regeneration in which a biodegradable polymer is introduced at one end or both ends of a pluronic polymer, a methacryloxyethyl trimellitic acid anhydride is conjugated to the biodegradable polymer, and a physiologically active substance is fixed to the methacryloxyethyl trimellitic acid anhydride, as well as a method for the preparation thereof. The pluronic derivative hydrogel according to the present invention exhibits high biodegradability due to the introduction of a biodegradable polymer while still maintaining the themosensitivity of the pluronic polymer itself and shows good biocompatibility owing to the coupling with a physiologically active substance capable of improving cell adhesion, proliferation and differentiation. Therefore, the pluronic derivative hydrogel according to the present invention can be effectively used in the regeneration of various kinds of tissues and organs. | 04-22-2010 |
| 20100129422 | POROUS BIODEGRADABLE POLYMER SCAFFOLDS FOR IN SITU TISSUE REGENERATION AND METHOD FOR THE PREPARATION THEREOF - The present invention relates to an intelligent porous biodegradable polymer scaffold for in situ tissue regeneration in which two kinds of physiologically active substances having high differentiation potential and biocompatibility are introduced into the polymer scaffold and conjugated to the surface thereof, respectively, and a method for the preparation thereof. Since the intelligent porous biodegradable polymer scaffold exhibits improved biocompatibility and differentiation potential due to the introduction of physiologically active substances capable of efficiently inducing cell proliferation and differentiation into both the surface and the inside thereof, it can directly induce in situ tissue regeneration of the musculoskeletal system from stem cells in a living tissue after transplanting the polymer scaffold and stem cells into a human body without additional in vitro cultivation. Therefore, the intelligent porous biodegradable polymer scaffold according to the present invention can be effectively used in the regeneration of various kinds of tissues and organs including the musculoskeletal system. | 05-27-2010 |
| 20100172262 | APPARATUS AND METHOD FOR DELAY TIME COMPUTATION AND DELAY COMPENSATION BETWEEN BASE STATION AND REMOTE RADIO FREQUENCY UNIT IN BROADBAND WIRELESS ACCESS SYSTEM - An apparatus and method for delay time computation and delay compensation between a Base Station (BS) and a remote Radio Frequency (RF) unit in a broadband wireless access system are provided. In a method of operating an apparatus for determining a delay time to compensate for delay between a BS modem card and a remote RF unit in a wireless access system, the method includes determining a process delay time required when traffic data is output from the BS modem card to an antenna of the remote RF unit in a state where a reference cable having a length short enough to neglect a cable delay time is connected between the BS modem card and the remote RF unit, determining a cable delay time required when a sync pulse signal is transmitted through a cable used in actual system operation between the BS modem card and the remote RF unit, and determining a time for outputting traffic data at an earlier time from a modem included in the BS modem card by using the determined process delay time and cable delay time. | 07-08-2010 |
| 20100279233 | METHOD FOR LASER INTERFERENCE LITHOGRAPHY USING DIFFRACTION GRATING - A method for laser interference lithography using a diffraction grating includes (a) forming a photoresist layer on a work substrate to which a repeated fine pattern is to be formed; (b) forming a refractive index matching material layer on the photoresist layer; (c) forming on the refractive index matching material layer a diffraction grating layer having a period of diffraction grating within the range from λ/n | 11-04-2010 |
| 20110111367 | NANOCOUPLING FOR IMPROVEMENT OF COATING ADHESION OF POLYMER ON METAL SUBSTRATES - Disclosed is nanocoupling of a polymer onto a surface of a metal substrate for improving coating adhesion of the polymer on the metal substrate, and in vivo stability and durability of the polymer. In accordance with the present invention, the polymers can be grafted via a chemical bonding on the surface of the metal substrate by the nanocoupling, by which adhesion, biocompatibility and durability of a polymer-coated layer which is to be formed later on the metal substrate were remarkably improved; therefore, the nanocoupling according to the present invention can be applied to surface modification of a metal implant, such as stents, mechanical valves, and an articular, a spinal, a dental and an orthopedic implants. | 05-12-2011 |
| 20110263018 | CORE-SHELL STRUCTURED DELIVERY SYSTEM FOR GROWTH FACTORS, A PREPARATION METHOD THEREOF, AND USE THEREOF FOR THE DIFFERENTIATION OR PROLIFERATION OF CELLS - The present invention relates to a method of preparing a delivery system capable of loading bioactive growth factors that are essential for the differentiation and proliferation of cells and is characterized as loading at least two types of components comprising growth factors in a single carrier, whereby the release of each of the plurality of growth factors can be temporally controlled. Specifically, the method of preparing a microcapsule type growth factor delivery system according to the present invention includes: (1) preparing a polymeric microsphere comprising a first component, and then encapsulating the microspheres by electrodropping the polymer microsphere into another polymer comprising a second component, thereby manufacturing a core-shell structured, microcapsule type delivery system, or (2) encapsulating a polymer solution comprising a first component by electrodropping the polymer solution into another polymer comprising a second component, thereby manufacturing a core-shell structured microcapsule type delivery system. The present invention also provides a stem cell differentiation method involving bringing a microcapsule type delivery system loaded with multiple growth factors according to the present invention into contact with stem cells. | 10-27-2011 |
| Patent application number | Description | Published |
|---|
| 20080218292 | Low voltage data transmitting circuit and associated methods - A low voltage data transmitting circuit (LVDTC) may be connected to a first transmission line that transmits a first voltage signal to a receiver and a second transmission line that transmits a second voltage signal to the receiver. The LVDTC includes a first resistor coupled to the first transmission line, a second resistor coupled to the second transmission line, and a control unit coupled to the first transmission line and the second transmission line, the control unit being configured to control voltage levels of the first and second voltage signals such that the voltage levels of the first and second voltage signals are higher than a ground voltage level of the receiver, wherein the first and second voltage signals may constitute a differential pair. | 09-11-2008 |
| 20090015537 | DISPLAY DEVICE TRANSFERRING DATA SIGNAL WITH CLOCK - A display device includes; a panel, a timing controller generating an embedded clock data signal combining image data and a clock signal, and a column driver driving the panel in response to the embedded clock data signal. The data bits within the embedded clock data signal are communicated at one of three voltage levels in a three-level signaling scheme, and the timing controller determines one of the three voltage levels for a current data bit (DIN[n]) within the embedded clock data signal in relation to a voltage level of a previous data bit (DIN[n−1]) within the embedded clock data signal. | 01-15-2009 |
| 20100244914 | CLOCK GENERATOR TO REDUCE LONG TERM JITTER - A clock generator includes a controller, a digital phase locked loop (PLL) circuit, a charge pump phase locked loop (PLL) circuit and a divider. The controller generates a division factor and a first internal clock signal in response to a low-frequency reference clock signal and a multiplication factor. The digital PLL circuit generates a second internal clock signal in response to the reference clock signal, the division factor and the first internal clock signal. The charge pump PLL circuit generates a plurality of third internal clock signals by using the second internal clock signal. The divider generates a high-frequency clock signal in response to a phase selection signal, the division factor and the third internal clock signals. | 09-30-2010 |
| 20110227616 | PHASE LOCKED LOOP CIRCUIT, METHOD OF DETECTING LOCK, AND SYSTEM HAVING THE CIRCUIT - Provided are a phase locked loop (PLL) circuit, a lock detector employable with a PLL circuit, a system including such a PLL circuit and/or lock detector, and a method of detecting a lock/unlock state of a PLL circuit. The PLL circuit may include a clock generating circuit configured to generate an output clock signal having a predetermined frequency in synchronization with a reference clock signal. The lock detector may be configured to determine that the PLL circuit is in a lock state when a phase difference between the reference clock signal and the output clock signal is equal to or less than a first reference value, determine that the PLL circuit is in an unlock state when the phase difference between the reference clock signal and the output clock signal is greater than a second reference value, and generate a lock detection signal. | 09-22-2011 |
| 20110227617 | PHASE LOCKED LOOP CIRCUIT AND SYSTEM HAVING THE SAME - A phase locked loop (PLL) circuit and a system including such a PLL that may at least compensate for leakage current in a loop filter. The PLL circuit may include a voltage adjusting unit configured to pump charges based on a phase difference between an oscillation clock signal and a reference clock signal, a loop filter configured to generate a frequency control voltage, a level of which is shifted by the charge pumping of the voltage adjusting unit, a voltage controlled oscillator (VCO) configured to output the oscillation clock signal having a frequency corresponding to the frequency control voltage, and a current control circuit configured to generate a compensation current corresponding to a leakage current generated by the loop filter and allow the compensation current and the leakage current to substantially and/or completely counterbalance each other. | 09-22-2011 |
