| Patent application number | Description | Published |
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| 20110116033 | Spectacles having retractable sidepieces - Spectacles include an optical or solar façade connected to two sidepieces which are each connected to the façade by a shaft which is substantially perpendicular to the façade and which is used to rotate each sidepiece about itself between a use position and a storage position in front of the façade having a radius of curvature substantially equal to that of the sidepiece. The sidepiece is divided into two portions, namely a first portion solidly connected to the central rotational shaft and a second portion connected to the first by an intermediate translational movement device disposed between the two portions and gradually engaging the second portion during the rotation of the first and consequently the second so as to subject the latter to two combined movements, one rotational and the other linear, for the automatic and simultaneous lengthening of the sidepiece as it is rotated to the use position and the shortening of the sidepiece as it is rotated to the storage position. | 05-19-2011 |
| 20110170051 | HINGELESS FLEXIBLE SPECTACLE ARM - An elastically deformable, hingeless spectacle arm is made exclusively of composite materials which have at least one layer of a reinforcing cloth and a coating or matrix made of a thermoplastic or heat-curable material. | 07-14-2011 |
| 20110170053 | NOSE BEARING ASSEMBLY FOR SPECTACLES, AND SPECTACLES INCLUDING SAME - A nose bearing assembly is secured onto a central area of the spectacles, directly on the optical or sun lenses, or on the bridge connecting the lenses or on a rim frame of the latter, each of the two nose bearing assemblies having a pad intended to contact the nose ala of a user and carried by a pad-bearing arm connected to the spectacles, characterized in that the pad is made of a elastically deformable material and is divided into two areas, i.e. an upper area for receiving a free end of the pad-bearing arm or securing and stiffening the pad in area, and another lower area capable of elastic deformation and of floating freely in all directions in order to obtain a self-adjustment of the pads independently from the morphology of the nose of the user when in contact with the latter. | 07-14-2011 |
| Patent application number | Description | Published |
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| 20080206254 | Novel Anti-Factor VIII Antibodies - The present invention relates to new antibodies and fragments and derivatives thereof, which are particularly suited for the characterization of the structure and function of Factor VIII (FVIII) of the coagulation pathway, for the design of therapeutic strategies for eradication of FVIII inhibitors and for the use as a medicament The invention also relates to cell lines producing the specific antibodies. The present invention furthermore relates to pharmaceutical compositions comprising the antibodies, fragments and/or derivatives of the Invention and to methods of preventing and treating cardiovascular disorders by using the antibodies or fragments and derivatives thereof or pharmaceutical compositions thereof. | 08-28-2008 |
| 20100266586 | VARIABLE ANTIBODIES - The present invention discloses inhibitory antibodies against Factor VIII with modified glycosylation, either by enzymatic deglycosylation or by site directed mutagenesis. Said antibodies with modified glycosylation have equal affinity for FVIII but show different inhibiting properties. The use of one or a mixture of said antibodies allow modulation of the inhibition of factor VIII to levels between 40 and 95%. The present invention further discloses pharmaceutical compositions comprising inhibitory antibodies against Factor VIII with modified glycosylation, combinations of these antibodies and methods for treating haemostasis disorders using said antibodies and antibody mixtures. | 10-21-2010 |
| 20100272715 | VARIABLE ANTIBODIES - The present invention discloses inhibitory antibodies against Factor VIII with modified glycosylation, either by enzymatic deglycosylation or by site directed mutagenesis. Said antibodies with modified glycosylation have equal affinity for FVIII but show different inhibiting properties. The use of one or a mixture of said antibodies allow modulation of the inhibition of factor VIII to levels between 40 and 95%. The present invention further discloses pharmaceutical compositions comprising inhibitory antibodies against Factor VIII with modified glycosylation, combinations of these antibodies and methods for treating haemostasis disorders using said antibodies and antibody mixtures. | 10-28-2010 |
| 20100322967 | B CELL TOLERANCE INDUCTION - The present invention relates to the induction of immune tolerance, by a novel method of induction of IL-10 production in B cells, whereby said B cells can be loaded with antigen before, during or after the induction of the IL-10 production. More specifically, the invention relates to the transduction of the B cell with a retroviral vector encoding an antigen, whereby the retroviral envelop induces IL-10 production in the B cell by activation the TLR2 receptor, in combination with its viral receptor. | 12-23-2010 |
