| Patent application number | Description | Published |
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| 20090088003 | ELECTRICAL CONNECTOR WITH PROTECTIVE MEMBER - A connector for connecting a card edge module to a circuit board includes a housing that extends along a longitudinal axis between opposite first and second end portions. The housing including a card slot configured to receive a mating edge of the card edge module and a channel proximate one of the first and second end portions. A protective member is received in the channel and positioned to inhibit contact between a side edge of the card edge module and the one of the first and second end portions of the housing when the card edge module is loaded into the connector. | 04-02-2009 |
| 20090317965 | ELECTRICAL CONTACT FOR TERMINATING A COAXIAL CABLE - An electrical contact is provided for terminating an electrical conductor of a coaxial cable. The electrical contact includes a body having a first element extending between a cable receiving end portion and a contact portion. The first element includes a first surface configured to engage the electrical conductor. A second element extends from the cable receiving end portion of the first element. The second element includes a second surface configured to engage the electrical conductor. The first and second elements are configured to hold a portion of the electrical conductor therebetween such that the coaxial cable extends outwardly from the cable receiving end portion of the first element. | 12-24-2009 |
| 20090318019 | ELECTRICAL CONNECTOR FOR TERMINATING A COAXIAL CABLE - An electrical connector is provided for terminating a coaxial cable. The electrical connector includes an electrically conductive housing extending a length between a cable-receiving end portion configured to engage an insulating cover of the coaxial cable and a mating end portion configured to engage another electrical connector. The housing includes an outer electrical contact. An insulating member is held by the housing. An inner electrical contact is held by the insulating member. The inner electrical contact includes a slot configured to receive an inner electrical conductor of the coaxial cable. | 12-24-2009 |
| 20090318020 | ADAPTER FOR A COAXIAL CABLE CONNECTOR - An adapter is provided for mating first and second coaxial cable connectors having first and second receptacle contacts, respectively. The adapter includes an inner electrical contact extending between opposite first and second plug contact end portions. The first plug contact end portion is configured to be received within the first receptacle contact of the first coaxial cable connector. The second plug contact end portion is configured to be received within the second receptacle contact of the second coaxial cable connector. The adapter also includes an outer electrical contact defining a receptacle. The outer electrical contact is configured to hold the inner electrical contact within the receptacle. | 12-24-2009 |
| 20090318021 | ULTRAMINIATURE COAX CONNECTOR - An ultraminiature coax connector (UMCC) is provided for terminating a coaxial cable. The UMCC includes an electrically conductive housing extending between a cable-receiving end portion and a mating end portion. The cable-receiving end portion being is configured to engage an insulating cover of the coaxial cable. The mating end portion is configured to engage another UMCC. The housing includes an outer electrical contact at the mating end portion. The outer electrical contact includes an outer diameter in the range of approximately one millimeter to approximately four millimeters or an inner diameter in the range of approximately one millimeter to approximately four millimeters. An insulating member is by the housing. An inner electrical contact is held by the insulating member. The inner electrical contact includes a plug contact portion that is configured to be received by a receptacle contact portion of the other UMCC. | 12-24-2009 |
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| 20100080791 | Composition and Method For Treating Tissue Defects - The present invention provides a composition and method for treating tissue defects. The composition includes thrombin and fibrinogen, or sodium alginate and calcium chloride, and also a surfactant, and non-resorbable polymer microparticles dispersed within the composition. | 04-01-2010 |
| 20100312358 | Implantable Repair Device - An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries. | 12-09-2010 |
| 20110172786 | Implantable Repair Device - An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries. | 07-14-2011 |
| 20110178608 | Implantable Repair Device - An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries. | 07-21-2011 |
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| 20090319045 | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles - Constructs that are at least partially constructed of allograft cancellous bone are disclosed, along with cartilage particles that may be used with the constructs for repairing articular cartilage defects. A multi-piece construct includes a base member, a cap member and at least one pin that secures the cap member to the base member. The base member may be constructed of mineralized cancellous bone, and is used to replace the subchondral bone removed when a surgeon cuts a bore in the area of an adjacent cartilage defect. The base member includes a blind bore and first and second through-going transverse bores in opposite sides of a wall of the base member. The cap member includes an upper section that has a thickness that is similar to that of a patient's surrounding articular cartilage layer and a stem depending from the upper section that is dimensioned to be received in and by the blind bore of the base member. The stem includes a transverse through-going bore, which may be aligned with the transverse through-going bores of the base member to receive the pin therein when the construct has been assembled. The cap member is at least partially formed of demineralized allograft cancellous bone, into which a mixture containing lyophilized, freeze-milled allograft cartilage particles may be infused for the repair of articular cartilage defects. The cartilage particles have a size within a range of from about 10 microns to about 210 microns. | 12-24-2009 |
| 20100274362 | Cartilage particle tissue mixtures optionally combined with a cancellous construct - Mixtures, such as gels or pastes, comprising freeze-milled cartilage particles and exogenous growth factors are used for repairing chondral defects. Such mixtures may be applied to constructs comprising cancellous bone for implantation at the defect site. Suitable growth factors include variants of FGF-2, particularly variants that include a sole amino acid substitution for asparagine at amino acid 111 of the β8-β9 loop of the FGF-2 peptide. Such FGF-2 variants are released slowly and continuously at a constant rate from cartilage pastes. In other embodiments, the amino acid substituted for asparigine is glycine. Other variants that may be used include FGF-9 variants having truncated chains and a sole amino acid substitution in the β8-β9 loop of the FGF-9 peptide either for tryptophan at amino acid 144 or for asparagine at amino acid 143. | 10-28-2010 |
| 20110004311 | SHAPED IMPLANTS FOR TISSUE REPAIR - Shaped constructs for repair of a defect in a body part or tissue of a subject are discussed herein. More specifically, implants suitable for delivery to a subject, such as a subject having a defect in a body part or body tissue, are discussed. Even more specifically, implants for intervertebral disc repair comprising corticocancellous bone, which can extend into the nucleus pulposus of an intervertebral disc and can be integrally attached to the annulus fibrosus of the disc to keep the implant in position, are described. Also, implants for meniscal repair comprising corticocancellous bone, which can extend from the outer edge of the meniscus to the inner region of the meniscus and can be integrally attached to the meniscal rim to keep the implant in position, are described. Implants for the repair of defects in bone, cartilage, and fibrocartilage are further described. Further described are methods for making such implants and for delivering the implants to a defect in a body part or body tissue of a subject. | 01-06-2011 |
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| 20100144601 | Anti-TNF Alpha Fibronectin Type III Domain Based Scaffold Compositions, Methods and Uses - A protein scaffold based on a consensus sequence of the tenth fibronectin type III (FN3) repeat from human fibronectin, preferably human Tenascin, that binds to human TNFα including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 06-10-2010 |
| 20100216708 | Fibronectin Type III Domain Based Scaffold Compositions, Methods and Uses - A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG have been identified as useful for diagnostic and/or therapeutic applications. | 08-26-2010 |
| 20100255056 | Fibronectin Type III Domain Based Scaffold Compositions, Methods And Uses - A protein scaffold based on a consensus sequence of the tenth fibronectin type III (FN3) repeat from human fibronectin, including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG based on the consensus sequence have been identified as useful for diagnostic and/or therapeutic applications. | 10-07-2010 |
| 20110189790 | Methods of Predicting Antibody Solubility - The invention provides methods for testing and ranking therapeutic antibody candidates for biophysical properties related to solubility and the susceptibility of the antibody to aggregate in aqueous solutions. The methods are useful for selecting among antibody libraries or variants for candidates which can be formulated at high concentrations. | 08-04-2011 |
| 20110274623 | Stabilized Fibronectin Domain Compositions, Methods and Uses - A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof, exhibit enhanced thermal and chemical stability while presenting six modifiable loop domains which can be engineered to form a binding partner capable of binding to a target for applications in diagnostic and/or therapeutic compositions, methods and devices. | 11-10-2011 |
