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Jacob, MA
Asha I. Jacob, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100222410 | Nuclease compositions and methods - The present invention generally relates to various nucleases and uses thereof, and in some cases, to the UPF0054 protein superfamily. Members of the UPF0054 protein superfamily, such as the | 09-02-2010 |
Emil Jacob, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090038180 | Dynamic Cushioning Assembly - A dynamic cushioning assembly to be used on beds, seats, backrests, shoes or any other surfaces where a portion of a body is subjected to prolonged contact and pressure with a support surface. The arrangement is comprised of a pattern of spherical elastic lugs cooperating with an upper, elastomeric layer. When a force is applied to the upper layer, the cooperation of the lugs with the upper layer create an uneven but soft surface having undulating zone of higher and lower resistance which serve to enhance blood circulation. | 02-12-2009 |
| 20090066121 | Transportation Vehicle Passenger Accommodation Assembly - A passenger accommodation assembly for a transportation vehicle, comprising a plurality of accommodation units placed along an aisle with each accommodation unit being convertible between an upright seat position and a reclined position. A first accommodation unit of the assembly is elevated relative to a second unit whereby the legs of a passenger reclining in the second unit can extend under a seat portion of the first unit and the backrest of the passenger in the first unit can extend over the legs of the passenger in the second unit. Other embodiments of the invention comprise multiple accommodation units and combinations of accommodation unit assemblies. | 03-12-2009 |
| 20090289896 | INPUT ARRANGEMENT FOR ELECTRONIC DEVICES - A new form of input arrangement for cursor control devices or other handheld electronic devices in which the activation surfaces are designed to allow the fingers and thumb of the user to affect commands by means of ergonomic and less repetitive motion as compared to current devices. In embodiments, sensors are associated with the user's digits which sense motion in not only the downward direction, but in multiple directions. In embodiments, the cursor control device has resilient pads to further add comfort to a user. The resulting ability of the user to vary and reduce the points of pressure and other stresses onto different surfaces of the digits and corresponding nerves and muscles serves to reduce discomfort and pain resulting from current devices. | 11-26-2009 |
Jacob M. Jacob, Franklin, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110173159 | DATA MOVER DISCOVERY OF OBJECT EXTENT - Performing data backup for a client includes receiving, at a host other than the client, volume information including data indicating a physical data storage location of at least a part of a volume comprising one or more stored objects associated with the client; and determining at the host, based at least in part on the volume information, a stored object information for a stored object included in the volume, the stored object information including data associated with a physical data storage location of the stored object. | 07-14-2011 |
Jonah Jacob, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090092162 | Means for improved implementation of laser diodes and laser diode arrays - A laser diode system is disclosed in which a substrate made of a semiconductor material containing laser diodes is bonded to a substrate made from a metallic material without the use of any intermediate joining or soldering layers between the two substrates. The metal substrate acts as an electrode and/or heat sink for the laser diode semiconductor substrate. Microchannels may be included in the metal substrate to allow coolant fluid to pass through, thereby facilitating the removal of heat from the laser diode substrate. A second metal substrate including cooling fluid microchannels may also be bonded to the laser diode substrate to provide greater heat transfer from the laser diode substrate. The bonding of the substrates at low temperatures, combined with modifications to the substrate surfaces, enables the realization of a low electrical resistance interface and a low thermal resistance interface between the bonded substrates. | 04-09-2009 |
Jules Jacob, Taunton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080260824 | Bioadhesive Rate-Controlled Oral Dosage Formulations - The present invention relates to a bioadhesive drug delivery system (BIOadhesive Rate controlled Oral Dosage (BIOROD) formulation) in which a drug containing core either alone or coated with a rate controlling membrane system is enveloped on its circumference by a bioadhesive coating, thereby yielding a monolithic system that allows for drug release in a regulated manner. Also described herein are polymers with improved bioadhesive properties and methods for improving bioadhesion of polymers. | 10-23-2008 |
| 20080299204 | Dosage forms for movement disorder treatment - The invention relates to the improvement in the treatment of certain neural disorders/diseases, such as Parkinson's disease and other motor disorders. One aspect of the invention relates to drug compositions and dosage forms comprising said drug composition. Another aspect of the invention relates to methods of manufacturing the drug compositions and dosage forms. Another aspect of the invention relates to methods of treatment, comprising administering the drug composition and dosage form to an individual. | 12-04-2008 |
| 20100316712 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF PARKINSON'S DISEASE AND RELATED DISORDERS - The invention relates to the improvement in the treatment of certain neural disorders/diseases, such as Parkinson's disease and other motor disorders. The invention relates to drug compositions and dosage forms comprising said drug composition; methods of manufacturing the drug compositions and dosage forms; and methods of treatment, comprising administering the drug composition and dosage form to an individual. In certain embodiments, the drug compositions and dosage forms comprise carbidopa and levodopa in a formulation suitable for once-daily administration. | 12-16-2010 |
| 20110086095 | Bioadhesive Polymers - Polymers and compositions, collectively “bioadhesive materials”, with improved bioadhesive properties have been developed. One or more compounds comprising: a) an aromatic moiety comprising two or more hydroxyl substituents, methoxy substituents, substituents hydrolyzable to hydroxyl substituents, or a combination thereof, and b) a primary or secondary amino moiety are either covalently attached to a polymer or are physically mixed with a polymer to form a bioadhesive material. These bioadhesive materials can be used, for example, to fabricate new drug delivery or diagnostic systems with increased residence time at tissue surfaces, and consequently increase the bioavailability of a drug or a diagnostic agent. | 04-14-2011 |
Jules Jacob, Taunion, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080311191 | Multi-Layer Tablets and Bioadhesive Dosage Forms - Bioadhesives coatings increase the gastrointestinal retention time of orally-ingested medicaments. Certain bioadhesive coatings producing a fracture strength of at least 100 N/m | 12-18-2008 |
Jules S. Jacob, Taunton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100172998 | PROCESS FOR PREPARING MICROPARTICLES THROUGH PHASE INVERSION PHENOMENA - A process for preparing nanoparticles and microparticles is provided. The process involves forming a mixture of a polymer and a solvent, wherein the solvent is present in a continuous phase and introducing the mixture into an effective amount of a nonsolvent to cause the spontaneous formation of microparticles. | 07-08-2010 |
Kenneth D. Jacob, Frammingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120132642 | Cooking Temperature and Power Control - A system and method for controlling the power delivered to cookware by a power control system that comprises a heating control user interface that is set by the user to a particular heating control user interface set point within an operating range. A controller derives from the heating control user interface set point a desired cookware temperature set point, and, over at least a first portion of the operating range that encompasses the boiling range, also derives from the heating control user interface set point a maximum limit of power that can be delivered to the cookware to maintain the cookware at the desired cookware temperature set point. The maximum power limit varies monotonically over the first portion of the operating range. | 05-31-2012 |
Kenneth D. Jacob, Framingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110064247 | Automated Customization of Loudspeakers - A loudspeaker includes a horn including a first end panel, a second end panel, a first side panel, and a second side panel. Edges of at least the first and second side panels define a diffraction slot opening. The first and second side panels are each fabricated from a sheet of flexible material held in a stressed, curved shape by at least a rigid support member. The panels are designed by an automated process based on a number of electro-acoustic transducers to be used in a loudspeaker, horizontal and vertical coverage angles for the loudspeaker, and a wall length for a horn of the loudspeaker. | 03-17-2011 |
| 20110135119 | AUTOMATED CUSTOMIZATION OF LOUDSPEAKERS - In general, in some aspects, a loudspeaker includes a horn including a first end panel, a second end panel, a first side panel, and a second side panel. Edges of at least the first and second side panels define a diffraction slot opening. A plurality of manifold components each has an output opening coupled to the diffraction slot opening. The output openings of the plurality of manifold components together constitute a diffraction slot source at the diffraction slot opening. A plurality of electro-acoustic transducers are each coupled to an input opening of one of the manifold components. | 06-09-2011 |
Kenneth Dylan Jacob, Framingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100002889 | SYSTEM AND METHOD FOR DESIGNING SOUND SYSTEMS - The invention is directed to a display and method for conducting sound system design. The display is configured to simultaneously show a sound system model comprising both audio components and sound environment components, a plurality of parameters and a graphic representation of a calculated sound system performance attribute. In response to receiving input from the user and without any additional user intervention, the display re-displays a newly-calculated sound system performance attribute such as, for example, a graphic representation in the sound system model of a sound path associated with a user-selected reflected sound identifier. A processor also simulates, based on the sound system configuration, the sound performance that a user would expect to hear positioned in an identified listening position of the sound system model. | 01-07-2010 |