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Izmailov
Alexandre Izmailov, Toronto CA
| Patent application number | Description | Published |
|---|---|---|
| 20090034902 | Method for Increasing Signal Intensity in An Optical Waveguide Sensor - A sensor platform for use in sample analysis comprises a substrate ( | 02-05-2009 |
| 20090177315 | Product, Dispenser and Method of Dispensing Product - A method of dispensing product includes determining by a processor if product loaded into a dispenser is authorized for use in the dispenser by identifying a reference indication associated with the product; in response to determination that the product is authorized, dispense a first amount of product; and in response to determination that the sheet product is unauthorized, dispense a second amount of sheet product, wherein the second amount of sheet product is different than the first amount. | 07-09-2009 |
| 20090294677 | METHOD FOR SIGNAL INTENSITY CORRECTION IN WAVEGUIDE SENSORS - Methods are provided for enhancing the detection of analytes with waveguides by accounting for cumulative light absorptions attributable to the presence of one or more analytes in a sample as well as the waveguide material. | 12-03-2009 |
| 20100267049 | DIAGNOSTIC DEVICES AND RELATED METHODS - Devices, systems, and methods for detecting the presence of one or more analytes in a sample are described. In some variations, a test strip may be used to detect and/or analyze one or more analytes in a sample. In certain variations, a test strip configured to receive a sample for detection of an analyte therein may comprise a substrate and a coating on a portion of the substrate, the coating comprising a combination of a first analyte capture agent configured to bind to a first analyte and a second analyte capture agent configured to bind to a second analyte that is different from the first analyte. | 10-21-2010 |
| 20100279429 | Method and Apparatus for Increasing the Sensitivity of a Biosensor Used in a Planar Waveguide - Systems, methods and apparatus are provided for mixing an analyte in a planar waveguide cartridge. The invention includes adding magnetic particles to an analyte containing one or more types of target molecules; inserting the analyte and magnetic particles into the cartridge; and moving a magnetic filed proximate to and around the cartridge containing the analyte and magnetic particles, wherein the movement of the magnet field causes movement in the analyte. | 11-04-2010 |
Alexandre Izmailov, Ontario CA
| Patent application number | Description | Published |
|---|---|---|
| 20110245483 | Method For Purification Of Nucleic Acids, Particularly From Fixed Tissue - The invention relates to a method for purification of nucleic acids, to a kit for performing the method according to the invention and to a new application of magnetic particles for purification of a biological sample. The method according to the invention comprises the following steps: a) accommodating of the sample in a first sample vessel in an aqueous solution and lysing of the sample under non-chaotropic conditions; suspending of first magnetic particles in the solution and inserting of the first sample vessel in a sample vessel holder, wherein the sample vessel is inserted in the annular interior space of a ring magnet associated with the sample vessel holder; separating of the solution from the magnetic particles; and isolating of the nucleic acids from the solution. | 10-06-2011 |
Alexandre M. Izmailov, Etobicoke CA
| Patent application number | Description | Published |
|---|---|---|
| 20080306694 | Methods for Detecting Peaks in a Nucleic Acid Data Trace - The present invention relates to methods and apparatus for detecting peaks in a sample nucleic acid data trace derived from a sample polynucleotide by (a) receiving a sequence signature of a reference polynucleotide, wherein the sequence signature comprises a profile of peak height at one or more peak position of a nucleic acid sequence data trace of one or more of reference polynucleotides; (b) receiving a sample nucleic acid sequence data trace of a sample polynucleotide corresponding to the reference polynucleotide, wherein the sample nucleic acid sequence data trace comprises a value of peak height at one or more peak position corresponding to the peak positions of the sequence signature; and (c) detecting peaks in the sample nucleic acid data trace having a peak height that correlates with the profile of peak height of the sequence signature at a corresponding peak position. | 12-11-2008 |
| 20080306696 | Methods for Resolving Convoluted Peaks in a Chromatogram - The present invention relates to methods for resolving convoluted peaks in a chromatogram into one or more constituent peaks using peak resolution values. The peaks methods of the invention determine empirical peak resolution values of “well-defined” or “isolated” peaks in the data, then extrapolate these empirical resolution values to peaks in neighboring regions to predict the number of constituent peaks at a given peak position. Predicted peak resolution values are compared to observed peak resolution values of low-resolution or convoluted peaks to determine the number of constituent peaks in the convoluted peaks. These methods enable extension of the region of data that can used for identifying nucleotide sequences, and increase base-calling accuracy in the low-resolution region (end region) of data. | 12-11-2008 |
Rauf Izmailov, Plainsboro, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080243731 | GENERALIZED SEQUENTIAL MINIMAL OPTIMIZATION FOR SVM+ COMPUTATIONS - A system and method for support vector machine plus (SVM+) computations include selecting a set of indexes for a target function to create a quadratic function depending on a number of variables, and reducing the number of variables to two in the quadratic function using linear constraints. An extreme point is computed for the quadratic function in closed form. A two-dimensional set is defined where the indexes determine whether a data point is in the two-dimensional set or not. A determination is made of whether the extreme point belongs to the two-dimensional set. If the extreme point belongs to the two-dimensional set, the extreme point defines a maximum and defines a new set of parameters for a next iteration. Otherwise, the quadratic function is restricted on at least one boundary of the two-dimensional set to create a one-dimensional quadratic function. The steps are repeated until the maximum is determined. | 10-02-2008 |