Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Izawa, Kawasaki-Shi
Hiroyuki Izawa, Kawasaki-Shi JP
| Patent application number | Description | Published |
|---|---|---|
| 20090048236 | NEW PHENYLALANINE DERIVATIVES - Specific phenylalanine derivatives or pharmaceutically acceptable salts thereof have an antagonistic effect on the α4 integrins and, therefore, are usable as therapeutic agents or preventive agents for diseases in which α4 integrin-depending adhesion process participates in the pathology, such as inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sjögren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection. | 02-19-2009 |
| 20110065918 | NEW PHENYLALANINE DERIVATIVES - Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin. | 03-17-2011 |
Kunisuke Izawa, Kawasaki-Shi JP
| Patent application number | Description | Published |
|---|---|---|
| 20080287687 | Production method of diphenylalanine-Ni (II) complex - The present invention relates to a production method of a compound represented by the formula (3), which includes reacting a compound represented by the formula (2) with a diphenylmethyl halide compound represented by the formula (1) in the presence of alkali metal alkoxide. According to the method of the present invention, compound (3) can be produced at a high purity and in a high yield. | 11-20-2008 |
| 20090005560 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS - The present invention relates to a novel production method of a diaminopyrimidine compound useful as an intermediate for various compounds having a pharmacological activity, a novel intermediate useful for producing said compound, and a production method of the intermediate. | 01-01-2009 |
| 20090137803 | 5-PROTECTED AMINOPYRIMIDINE COMPOUND, PRODUCTION METHOD THEREOF AND INTERMEDIATE THEREFOR - The present invention provides a production method of 5-aminopyrimidine compound represented by the formula (5) by reacting a glycine compound represented by the formula (1) with t-butoxybisdimethylaminomethane, dimethylformamidedimethylacetal or dimethylformamidediethylacetal to produce a dialkylaminomethylene compound represented by the formula (2), reacting the compound of formula (2) in the presence of an acid to produce a hydroxymethylene compound represented by the formula (3), and reacting the compound of formula (3) with an amidine compound represented by the formula (4) or a salt thereof. | 05-28-2009 |
| 20090171084 | PRODUCTION METHOD OF AMINOPYRIMIDINE COMPOUND - Aminopyrimidine compounds represented by formula (3) may be efficiently prepared by reacting an azlactone compound represented by formula (1) with an amidine compound represented by formula (2) or a salt thereof: | 07-02-2009 |
| 20090258398 | Process for the Production of beta-Amino Acids Using Acylase - The present invention relates to a | 10-15-2009 |
| 20110028706 | INOSINE DERIVATIVES AND PRODUCTION METHODS THEREFOR - The present invention provides a method for producing an inosine derivative represented by the following general formula (1) including the steps of subjecting an inosine derivative of general formula (3) to dithiocarbonylation and carrying out radical reduction of the obtained compound. According to the present invention there can be produced compounds useful as anti-AIDS drugs on industrial scale. | 02-03-2011 |