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Izabela Fokt, Houston US

Izabela Fokt, Houston, TX US

Patent application numberDescriptionPublished
20100022466THERMALLY-TARGETED DELIVERY OF MEDICAMENTS INCLUDING DOXORUBICIN - Elastin-like polypeptide (ELP) serves as a vector for thermally-targeted delivery of therapeutics, including cytotoxic chemotherapeutic drugs such as doxorubicin. Examples of an ELP-based delivery vehicle can comprise: (1) a cell penetrating peptide, such as a Tat protein, (2) ELP, and (3) the lysosomally degradable glycylphenylalanylleucylglycine (GFLG) spacer and a cysteine residue conjugated to therapeutic such as doxorubicin, or a analog thereof.01-28-2010
20100130434Hexose Compounds to Treat Cancer - Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a hexose compound to a subject in need thereof The subject invention includes methods of treating brain and pancreatic cancer comprising the administration of a therapeutically effective amount of a mannose compound to a subject in need thereof The subject invention further includes methods of treating the proliferation of tumors comprising the administration of a therapeutically effective amount of 2-FM to a subject in need thereof.05-27-2010
20100144802Small Molecule Inhibitors for Immune Modulation - Methods of treating immunosuppression by administering a therapeutic amount of a tryphostin compound of the formula:06-10-2010
20100152121Iodo-Hexose Compounds Useful to Treat Cancer - Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a iodo-hexose compound to a subject in need thereof. The subject disclosure includes methods of treating glioblastoma and pancreatic cancer comprising the administration of a therapeutically effective amount of a 2-deoxy-2-iodo-D-hexose compound including 2-deoxy-2-iodo-D-mannose, 2-deoxy-2-iodo-D-glucose, 2-deoxy-2-iodo-D-galactose, and/or 2-deoxy-2-iodo-D-talose to a subject in need thereof.06-17-2010
20110003758Inhibitors of Glycolysis Useful In the Treatment of Brain Tumors - Provided herein are methods of treating brain tumors by administering a therapeutically effective amount of a compound of the Formulas I or II to a patient in need thereof.01-06-2011
20110021805COMPOUNDS FOR TREATMENT OF CELL PROLIFERATIVE DISEASES - The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. Compounds of the present invention display significant potency as kinase inhibitors, cause the downregulation of c-myc, and inhibit the growth and survival of cancerous cell lines.01-27-2011
20110053992Novel Inhibitors of Proliferation and Activation of Signal Transducer and Activator of Transcription (STATS) - Pyridine compounds effective in modulation STAT3 and/or STAT5 activation are provided that are useful in the prevention and treatment of proliferative disease and conditions including cancer, inflammation and proliferative skin disorders.03-03-2011
20110160151Novel Acetates of 2-Deoxy Monosaccharides with Anticancer Activity - Novel compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are provided herein.06-30-2011

Patent applications by Izabela Fokt, Houston, TX US