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Iwatsubo
Kosaku Iwatsubo, Fort Lee, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110021453 | Methods and compositions for providing cardiac protection - The invention provides a method of treating a cardiac disease by administering a pharmaceutically effective amount of at least one compound capable of inhibiting AC5 to a patient. The compound capable of inhibiting AC5 may be administered singly or in combination with another agent, such as, for instance a β-blocker. In some embodiments, the AC5 inhibiting compound is 9-β-D-arabinofuranosyladenine (AraAde). The compound may be administered in an amount of about 1 to about 200 mg/kg/day, about 1 to about 100 mg/kg/day, about 10 to about 80 mg/kg/day, about 12 to about 40 mg/kg/day or about 15 to about 25 mg/kg/day. In some embodiments, the compound is administered parenterally. The cardiac disease may be, for instance, myocardial infarction (MI) or heart failure (HF). The compound capable of inhibiting AC5 may be administered alone or in conjunction with one or more other active agents. Likewise, the invention provides a method of treating a heart attack, a method of inhibiting myocardial apoptosis, and a method of treating heart failure by administering a pharmaceutically effective amount of at least one compound capable of inhibiting AC5 to a patient in the same manner. | 01-27-2011 |
| 20110060029 | METHOD OF TREATING CANCER BY MODULATING EPAC - Methods of treating cancer by preventing, mitigating, and/or inhibiting cancer metastasis in tumors expressing Epac by inhibiting the activity of exchange proteins directly activated by cyclic AMP (Epac) or one or more proteins within the Epac-induced carcinoma migration pathway. | 03-10-2011 |
Mitsugu Iwatsubo, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20110204095 | SQUEEZE CONTAINER - A squeeze container includes a container body having flexibility, and a press restriction member that is provided inside the container body and that restricts, from inside the container body, deformation of the container body due to pressing of a side surface of the container body from outside thereof. A content liquid of the container is discharged by pressing the side surface of the container body from outside thereof. The squeeze container has, on the side surface of the container body, measurement scale markings arrayed in the vertical direction. The inner diameter of the container body within an arrayed range in which the measurement scale markings are arrayed in the vertical direction is formed to have a smaller diameter than an upper portion and/or a lower portion of the container body. Further, there is a corresponding relationship between a position, in the vertical direction, on the array of the measurement scale markings and a discharge amount when that position is pressed. | 08-25-2011 |
Takeshi Iwatsubo, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20090220524 | THERAPEUTIC AGENTS FOR ALZHEIMER'S DISEASE AND CANCER - To provide a therapeutic drug for Alzheimer's disease and/or a cancer. | 09-03-2009 |
| 20090280530 | NOVEL COLLAGEN-LIKE PROTEIN CLAC, PRECURSOR THEREOF AND GENES ENCODING THE SAME - A novel human collagen-like protein CLAC occurring in brain amyloid and its precursor CLAC-P; genes encoding the same; cDNA of mouse CLAC-P and its deduced amino acid sequence; antibodies specific to these proteins; and methods of diagnosing treating and preventing Alzheimer's disease by using the same. | 11-12-2009 |
| 20100004433 | NOVEL COLLAGEN-LIKE PROTEIN CLAC, PRECURSOR THEREOF AND GENES ENCODING THE SAME - A novel human collagen-like protein CLAC occurring in brain amyloid and its precursor CLAC-P; genes encoding the same; cDNA of mouse CLAC-P and its deduced amino acid sequence; antibodies specific to these proteins; and methods of diagnosing treating and preventing Alzheimer's disease by using the same. | 01-07-2010 |
| 20110137013 | NOVEL COLLAGEN-LIKE PROTEIN CLAC, PRECURSOR THEREOF AND GENES ENCODING THE SAME - A novel human collagen-like protein CLAC occurring in brain amyloid and its precursor CLAC-P; genes encoding the same; cDNA of mouse CLAC-P and its deduced amino acid sequence; antibodies specific to these proteins; and methods of diagnosing treating and preventing Alzheimer's disease by using the same. | 06-09-2011 |
Takeshi Iwatsubo, Bunkyo-Ku JP
| Patent application number | Description | Published |
|---|---|---|
| 20110165179 | THERAPEUTIC AGENTS FOR ALZHEIMER'S DISEASE AND CANCER - To provide a therapeutic drug for Alzheimer's disease and/or a cancer. | 07-07-2011 |
Takuzo Iwatsubo, Suita-Shi JP
| Patent application number | Description | Published |
|---|---|---|
| 20090005188 | Analysis method of golf club - According to the present invention, a torque applied from a golf player to a golf club during a swing is analyzed in a time-series manner. A DLT method is suitable as a determination procedure. Preferably, a link model is used in this analysis. Preferably, the three-dimensional coordinate of the mark provided at a position that corresponds to the link model is determined by a DLT method. Preferable analysis method includes: modeling using a golf club, and at least a part of a golf player who grips a grip member of the golf club to provide a link model in which the golf club is connected with the golf player via a joint; and analyzing the torque that acts on the joint is analyzed during the swing in a time-series manner. This joint is positioned in the vicinity of the grip member. This analysis can be applied to a method of diagnosing a swing, a method of selecting a golf club, and a method of designing a golf club. | 01-01-2009 |
Takuzo Iwatsubo, Osaka JP
| Patent application number | Description | Published |
|---|---|---|
| 20110130214 | METHOD FOR DESIGNING GOLF CLUB AND GOLF CLUB - A designing method of the present invention includes the steps of: measuring a golf swing to obtain a measured result; obtaining a swing model provided with a link model and joint torque data based on the measured result, the link model having at least two links; performing simulation for swing the golf club using the swing model; and obtaining head information in a specific situation during a swing based on a result of the simulation. In the designing method, a plurality of specifications of the golf club and/or the plurality of swing models are used to obtain the plurality of head information, and stability is evaluated using a difference between the head information. In the designing method, it was found that a great lateral moment of inertia of a head and a small depth of a center of gravity of the head contribute to the stability. | 06-02-2011 |