Patent application number | Description | Published |
20080293667 | Lipid analogs for combating tumors - The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the activity of the viral infection. | 11-27-2008 |
20100184718 | Compositions and Methods for Double-Targeting Virus Infections and Targeting Cancer Cells - The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions of the invention include compounds which comprise a phosphocholine moiety covalently conjugated with one or more antiviral agents (e.g. nucleoside analogue, protease inhibitor, etc.) to a lipid backbone. The invention also includes pharmaceutical compositions and kits for use in treatment of a virus infection in mammals. The methods of the invention comprise administering a compound of the invention, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of the invention, in an amount effective to treat the infection, to a mammal infected with a virus. Additionally, the invention includes compositions and methods useful for combating a cancer in a mammal and for facilitating delivery of a therapeutic agent to a mammalian cell. The compositions of the invention include compounds which comprise an alkyl lipid or phospholipid moiety covalently conjugated with an anticancer agent (e.g. a nucleoside analogue). The invention also includes pharmaceutical compositions and kits for combating a cancer and for facilitating delivery of a therapeutic agent to a mammalian cell. The methods of the invention comprise administering a compound of the invention, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of the invention, in an amount effective to combat a cancer or to facilitate delivery of a therapeutic agent to a mammalian cell. | 07-22-2010 |
20100273740 | Phospholipids for the Treatment of Infection by Togaviruses, Herpes Viruses and Coronaviruses - Provided are compounds, methods and pharmaceutical compositions for treating a host, especially a human, infected with a togavirus, herpes virus and/or coronavirus, and in particular SARS-CoV, cytomegalovirus or varicella-zoster virus. The method in one embodiment comprises administering to that host an effective amount of an anti-togavirus, anti-herpes virus and/or anti-coronavirus phospholipid or a pharmaceutically acceptable salt or prodrug thereof. The phospholipid compound is, e.g., a 3-alkylamido-2-alkoxypropylphosphocholine compound or salt thereof. The compound may be administered alone or in combination and/or alternation with one or more other anti-viral agents. | 10-28-2010 |
Patent application number | Description | Published |
20130248112 | VACUUM TRAP - A vacuum trap, a plasma etch system using the vacuum trap and a method of cleaning the vacuum trap. The vacuum trap includes a baffle housing; and a removable baffle assembly disposed in the baffle housing, the baffle assembly comprising a set of baffle plates, the baffle plates spaced along a support rod from a first baffle plate to a last baffle plate, the baffle plates alternately disposed above and below the support rod and alternately disposed in an upper region and a lower region of the baffle housing. | 09-26-2013 |
20140251443 | APPARATUS AND METHOD FOR CONTROLLED ACCESS TO PRESSURIZED FLUID LINES AND TO EXHAUSTED LINES - A method and apparatus for controlled access to pressurized fluid lines and to exhausted lines. The apparatus includes a rod body having a bore; a packing fitting attached to a first end of the rod body and a ball valve attached to a second end of the rod body; a transverse arm between the first and second ends of the rod body, the transverse arm having a bore communicating the rod body bore; and a slideable rod in the bore of the rod body, in a first position of the rod a first end extends through the packing fitting to outside of the rod body and a second end is completely within the rod body, in a second position of the rod the first end extends through the packing fitting to outside of the rod body and the second end of the rod extends through and past the ball valve. | 09-11-2014 |
20150262795 | VACUUM TRAP - A vacuum trap, a plasma etch system using the vacuum trap and a method of cleaning the vacuum trap. The vacuum trap includes a baffle housing; and a removable baffle assembly disposed in the baffle housing, the baffle assembly comprising a set of baffle plates, the baffle plates spaced along a support rod from a first baffle plate to a last baffle plate, the baffle plates alternately disposed above and below the support rod and alternately disposed in an upper region and a lower region of the baffle housing. | 09-17-2015 |