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Isham, US

Crescent R. Isham, Rochester, MN US

Patent application numberDescriptionPublished
20090264421Methods and Compositions for Treating Cancer - Compositions and methods for treating cancer, including hematologic cancers such as multiple myeloma, are disclosed. In some embodiments, chaetocin, chaetomin, or gliotoxin can be used to treat or ameliorate one or more symptoms or disorders associated with multiple myeloma.10-22-2009

John Isham, Houston, TX US

Patent application numberDescriptionPublished
20080200872MINIMALLY INVASIVE RECTAL BALLOON APPARATUS - A rectal balloon apparatus has a shaft with a fluid passageway extending therethrough. A balloon is affixed over an end of the shaft such that the fluid passageway communicates with an interior of the balloon. The balloon has a laterally flat surface thereon when inflated. The laterally flat surface of the balloon has a longitudinal groove formed thereon. The balloon having a pair of bulges formed thereon when the balloon is inflated. A ring is affixed to the shaft adjacent the balloon. The shaft has a plurality of holes formed thereon opening to an interior of the balloon.08-21-2008
20080300619RECTAL BALLOON APPARATUS WITH RADIATION SENSOR AND/OR MARKERS - A rectal balloon apparatus has a shaft with a fluid passageway extending therethrough. A balloon is affixed over an end of the shaft such that the fluid passageway communicates with an interior of the balloon. The balloon has a laterally flat surface thereon when inflated. The laterally flat surface of the balloon has a longitudinal groove formed thereon. The balloon has a radiation sensor positioned within the groove and a plurality of fiducial markers positioned on a surface of the balloon. A stopper is slidably mounted on the shaft.12-04-2008
20090221899MINIMALLY INVASIVE RECTAL BALLOON APPARATUS WITH PRESSURE RELIEVING LUMEN AND ANAL VERGE DILATION COLLAR - A rectal balloon apparatus has a shaft with a fluid passageway extending therethrough. A balloon is affixed over an end of the shaft such that the fluid passageway communicates with an interior of the balloon. A collar is affixed around the shaft which is suitable for dilating a patient's anal verge. The collar is a color distinct from the colors of the balloon and the shaft. The collar has a first section hingedly connected to a second section so as to allow the collar to be selectively affixed to the shaft. The collar has an outer diameter that is roughly twice an outer diameter of the shaft. The collar can be snap-fitted around the shaft.09-03-2009
20100145132Dual Gynecological Balloon Packing System - A gynecological balloon apparatus has a first balloon and a second balloon disposed with a gynecological brachytherapy applicator. The first and second balloons are each movable between an inflated condition and a deflated condition. The first and second balloons may conform to a shape of a vaginal cavity when in their inflated conditions. A radiation detecting sensor and a motion detecting sensor may be positioned with the apparatus.06-10-2010
20100145379Rectal Balloon Apparatus with Pressure Relieving Lumen and Sensors - A rectal balloon apparatus comprises a shaft having a fluid passageway extending therethrough. A rectal gas relieving lumen may be positioned with the shaft for removal of rectal gas. A motion detecting sensor and a radiation detecting sensor may be positioned with the balloon, the shaft, and/or the rectal gas release lumen.06-10-2010
20100179582Minimally Invasive Rectal Balloon Apparatus - A rectal balloon apparatus has a shaft with a fluid passageway extending therethrough. A balloon is affixed over an end of the shaft such that the fluid passageway communicates with an interior of the balloon. The balloon has a laterally flat surface thereon when inflated. The laterally flat surface of the balloon has a longitudinal groove formed thereon. A valve assembly is affixed to the shaft at an end opposite the balloon. The valve assembly selectively allows a fluid to pass therethrough to move the balloon from a non-inflated condition to an inflated condition. A fluid introducing means is removably attached to the valve assembly to introduce the fluid into the valve assembly.07-15-2010

Patent applications by John Isham, Houston, TX US

Robert Isham, Flemington, NJ US

Patent application numberDescriptionPublished
20080238392CONTROLLER AND DRIVER COMMUNICATION FOR SWITCHING REGULATORS - Pulse width modulation (PWM) controllers and output stage driver circuits and related methods of communicating switching regulator mode information. The controller includes circuitry that recognizes intervals when the load driven by the regulator is in a low power mode. Responsive to recognizing the low power mode, the controller generates a PWM mode signal having at least three (3) different levels including at least one intermediate level that is coupled to at least one driver. Based on the PWM mode signal, the regulator is switched into a power saving low power operational mode.10-02-2008
20080284398Controller having comp node voltage shift cancellation for improved discontinuous conduction mode (DCM) regulator performance and related methods - A modulation controller includes an error amplifier which receives a reference voltage and an output voltage (V11-20-2008
20100079175PHASE DOUBLER - A phase doubler driver circuit includes a first input for receiving a input PWM drive signal. First control logic generates a first output PWM drive signal and a second output PWM drive signal responsive to the input PWM drive signal. In a first mode of operation, alternating pulses of the input PWM drive are output as the first output PWM drive signal and the second PWM output drive signal respectively. In a second mode of operation, the input PWM drive signal is provided as the first output PWM drive signal when a second phase current associated with the second output PWM drive signal exceeds a first phase current associated with the first output PWM drive signal and the input PWM drive signal is provided as the second output PWM drive signal when the phase current associated with the first output PWM signal exceed the phase current associated with the second output PWM signal. Second control logic adds an offset to a falling edge of the first output PWM drive signal responsive to a difference between a first current associated with the first phase current and an average current and for adding the offset to a falling edge of the second output PWM signal responsive to a difference between a second current associated with the second phase current and the average current, wherein the average current comprises the average of the first current and the second current. Drive circuitry generates drive signals responsive to each of the first output PWM drive signal and the second output PWM drive signal.04-01-2010
20100283523CONTROLLER AND DRIVER COMMUNICATION FOR SWITCHING REGULATORS - Pulse width modulation (PWM) controllers and output stage driver circuits and related methods of communicating switching regulator mode information. The controller includes circuitry that recognizes intervals when the load driven by the regulator is in a low power mode. Responsive to recognizing the low power mode, the controller generates a PWM mode signal having at least three (11-11-2010
20110133716CONTROLLER AND DRIVER COMMUNICATION FOR SWITCHING REGULATORS - Pulse width modulation (PWM) controllers and output stage driver circuits and related methods of communicating switching regulator mode information. The controller includes circuitry that recognizes intervals when the load driven by the regulator is in a low power mode. Responsive to recognizing the low power mode, the controller generates a PWM mode signal having at least three (3) different levels including at least one intermediate level that is coupled to at least one driver. Based on the PWM mode signal, the regulator is switched into a power saving low power operational mode.06-09-2011
20110133717CONTROLLER AND DRIVER COMMUNICATION FOR SWITCHING REGULATORS - Pulse width modulation (PWM) controllers and output stage driver circuits and related methods of communicating switching regulator mode information. The controller includes circuitry that recognizes intervals when the load driven by the regulator is in a low power mode. Responsive to recognizing the low power mode, the controller generates a PWM mode signal having at least three (3) different levels including at least one intermediate level that is coupled to at least one driver. Based on the PWM mode signal, the regulator is switched into a power saving low power operational mode.06-09-2011

Patent applications by Robert Isham, Flemington, NJ US

Stephen Isham, Kalamazoo, MI US

Patent application numberDescriptionPublished
20100036335REMOVABLE INLET MANIFOLD FOR A MEDICAL/SURGICAL WASTE COLLECTION SYSTEM, THE MANIFOLD INCLUDING A DRIVER FOR ACTUATING A VALVE INTEGRAL WITH THE WASTE COLLECTION SYSTEM - A removable manifold for a medical/surgical waste collection system. The manifold is dimensioned to be mounted to a receiver integral with the system. The manifold includes a driver for engaging a complementary valve internal to the receiver. The valve regulates flow between the receiver and the down line components of the waste collection system. The valve is normally closed. When the manifold is fitted to the receiver the driver engages the valve so as move the valve to the open position. This allows fluid flow from the manifold and receiver to the downstream components of the system.02-11-2010

Stephen P. Isham, Kalamazoo, MI US

Patent application numberDescriptionPublished
20090159535METHOD OF COLLECTING MEDICAL WASTE IN A WASTE COLLECTION UNIT USING DISPOSABLE MANIFOLD WITH STAGED WASTE FILTERING/PROCESSING - A method of collecting medical waste in a waste collection unit using a disposable manifold and filter assembly. The disposable manifold and filter assembly includes a manifold housing with a plurality of inlets, a neck extending from the manifold housing to define an outlet, and a filter basket disposed in the manifold housing. The method includes inserting the neck into the waste collection unit to direct the medical waste passing through the disposable manifold and filter assembly into the waste collection unit. Tubes are connected to the inlets of the manifold housing to provide a path for the medical waste to travel from a target site, e.g., a patient, to the manifold housing. A vacuum is drawn in the waste collection unit to pull the medical waste through the tubes and into the disposable manifold and filter assembly where the medical waste is processed/filtered in a plurality of stages.06-25-2009
20100049152MEDICAL/SURGICAL WASTE COLLECTION AND DISPOSAL SYSTEM INCLUDING A ROVER AND A DOCKER, THE DOCKER HAVING FEATURES FACILITATING THE ALIGNMENT OF THE DOCKER WITH THE ROVER - A waste collection and disposal system for use in health care facilities is provided. The system includes a mobile waste collection unit for moving between use areas in the health care facility to collect waste material generated during medical procedures including body fluids, body tissues, saline, etc. The waste collection unit includes stacked upper and lower waste containers for receiving the waste material. During use, the upper waste container can be emptied into the lower waste container for temporary storage. In addition, different vacuum levels can be provided in the waste containers during complex procedures. Once a user desires to empty the waste collection unit, the waste collection unit is wheeled to a docking station. At the docking station, the waste material is off-loaded to a waste drain and the waste collection unit is cleaned and rinsed for further use.02-25-2010

Patent applications by Stephen P. Isham, Kalamazoo, MI US

William R. Isham, Alpine, UT US

Patent application numberDescriptionPublished
20080251969Bladder Molding Systems and Methods For Fabricating Composite Articles - A method for forming composite articles from a thermoplastic preform using a bladder molding system. In one aspect, the method comprises suspending the preform above a tensioned release layer in an indexed manner prior to heating and forming the preform. In another aspect, the method comprises cold loading the preform into the bladder molding system about the mold cavity and subsequently heating and forming the preform without further handling the preform.10-16-2008

Patent applications by William R. Isham, Alpine, UT US