Isabella
Isabella Attinger-Toller, Zürich CH
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20160076011 | Human Serum Albumin Binding Compounds and Fusion Proteins Thereof - The present invention relates to a polypeptide binding to human serum albumin and comprising or consisting of an amino acid sequence selected from the group consisting of: (a) GVTLFVALYDY(X | 03-17-2016 |
Isabella Audo, Paris FR
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20130071373 | METHODS FOR THE DIAGNOSIS AND THERAPY OF RETINITIS PIGMENTOSA - The present invention relates to a method of identifying a subject having or at risk of having or developing a retinitis pigmentosa, comprising detecting in a sample obtained from said subject, the presence of at least one mutation in the rhodopsin (RHO) gene selected from the group consisting of c.263T>C, c.620T>A and c. 1031A>C wherein the presence of said mutation indicates an increased risk of having or being at risk of having or developing the retinitis pigmentosa. | 03-21-2013 |
Isabella Bettenbacher, Gersthofen DE
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20100193724 | COPOLYMERS CONTAINING PERFLUOROALKYL GROUPS AND AQUEOUS DISPERSIONS THEREOF - Copolymers which are composed of at least 4 monomers, including (meth)acrylate compounds containing perfluoroalkyl groups, are suitable for the treatment of fiber materials. The copolymers are usually used here in the form of aqueous dispersions. The fiber materials are in particular fabrics, for example made of polyolefin. Treatment with the copolymers imparts to them oil- and water-repellent properties and also repellent properties toward low molecular weight alcohols. | 08-05-2010 |
Isabella Caniggia, Toronto CA
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20090098146 | METHODS TO DIAGNOSE A REQUIRED REGULATION OF TROPHOBLAST INVASION - Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-β | 04-16-2009 |
20090239793 | Polynucleotides and polypeptides associated with trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover - The invention relates to polypeptides and polynucleotides associated with trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover, and uses of same in the prevention, diagnosis and treatment of conditions requiring regulation of trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover. In particular aspects, diagnostic methods are disclosed for evaluating conditions such as preeclampsia utilizing matador polypeptides and polynucleotides encoding same. | 09-24-2009 |
20090246773 | DIAGNOSTIC COMPOSITIONS AND TREATMENT METHODS FOR CONDITIONS INVOLVING TROPHOBLAST CELL DEATH, DIFFERENTIATION, INVASION AND/OR CELL FUSION AND TURNOVER - The invention provides a method for diagnosing in a subject a condition requiring modulation of or involving trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover, comprising detecting HIF Iα and the factors which modulate or are modulated by this protein, specifically TGFβ3, sFLT, VEGF, SMAD2, 3 and 7, MtdP, MtdL, MclI 1, MclIc, VHL, SiahI, Siah2, ENG, and PHD. The invention also provides a method for diagnosing or distinguishing in a subject a specific condition requiring modulation of or involving trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover, in particular early onset severe preeclampsia (EPE), late onset preeclampsia (LPE) and mtre-uterme growth restriction (IUGR) comprising detecting HLF Iα and the factors which modulate or are modulated by this protein as defined above. | 10-01-2009 |
20100291708 | METHODS TO DIAGNOSE A REQUIRED REGULATION OF TROPHOBLAST INVASION - Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-β | 11-18-2010 |
20120064087 | METHODS TO DIAGNOSE A REQUIRED REGULATION OF TROPHOBLAST INVASION - Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-β | 03-15-2012 |
20130280736 | REAGENTS AND METHODS FOR DIAGNOSING CONDITIONS ASSOCIATED WITH HYDROXYLATED HIF 1-ALPHA - The invention relates to reagents and methods for detecting, diagnosing and screening for conditions associated with hydroxylated hypoxia inducible factor 1-α (HIF-1α). The invention also relates to novel monoclonal antibodies specific for hydroxylated HIF-1α, or binding fragments thereof, and related nucleic acids, vectors, cells and compositions, as well as methods of using the antibodies in methods of the invention. | 10-24-2013 |
20140038908 | Polynucleotides and Polypeptides Associated with Trophoblast Cell Death, Differentiation, Invasion and/or Cell Fusion and Turnover - The invention relates to polypeptides and polynucleotides associated with trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover, and uses of same in the prevention, diagnosis and treatment of conditions requiring regulation of trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover. In particular aspects, diagnostic methods are disclosed for evaluating conditions such as preeclampsia utilizing matador polypeptides and polynucleotides encoding same. | 02-06-2014 |
Isabella Flodström, Goteborg SE
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20150225835 | METHOD & STEEL COMPONENT - A method for heat treating a steel component, the method comprising steps of: (a) carbonitriding the steel component and (b) ferritically nitrocarburizing the steel component. | 08-13-2015 |
20150240341 | METHOD & STEEL COMPONENT - A method for heat treating a steel component, which comprises the steps of: (a) carbonitriding the steel component, and (b) austenitically nitrocarburizing the steel component. | 08-27-2015 |
Isabella Gashaw, Berlin DE
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20140249119 | Estra-1,3,5(10),16-tetraene-3-carboxamide derivatives, processes for their preparation, pharmaceutical preparations comprising them and their use for preparing medicaments - The invention relates to AKR1C3 inhibitors and to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular bleeding disorders and endometriosis. | 09-04-2014 |
Isabella Gashaw, San Francisco, CA US
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20140288035 | 18-METHYL-6,7-METHYLENE-3-OXO-17-PREGN-4-ENE-21,17B-CARBOLACTONES, PHARMACEUTICAL PREPARATIONS COMPRISING SAID COMPOUNDS AND USE THEREOF IN THE TREATMENT OF ENDOMETRIOSIS - The present invention relates to 18-methyl-6,7-methylene-17-pregn-4-ene-21,17β-carbolactones of general formula I | 09-25-2014 |
Isabella Goldmints, Niskayuna, NY US
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20150184105 | VISCOSITY INDEX IMPROVER CONCENTRATES FOR LUBRICATING OIL COMPOSITIONS - Concentrates of linear, block copolymers having a polymer block derived from a monoalkenyl arene, covalently linked to one or more blocks of a hydrogenated derivative of a conjugated diene copolymer, dissolved in highly saturated diluent oil, wherein the size of the monoalkenyl arene block is controlled to provide an optimized level of incompatibility of the block copolymer in the selected diluent. | 07-02-2015 |
20150184108 | VISCOSITY INDEX IMPROVER CONCENTRATES FOR LUBRICATING OIL COMPOSITIONS - Concentrates of linear, block copolymers having a polymer block derived from a monoalkenyl arene, covalently linked to one or more blocks of a hydrogenated derivative of a conjugated diene copolymer, dissolved in highly saturated diluent oil, wherein the size of the monoalkenyl arene block is controlled to provide an optimized level of incompatibility of the block copolymer in the selected diluent. | 07-02-2015 |
Isabella Hebeiss, Widdern DE
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20130344529 | VASCULAR MODEL, METHOD FOR PRODUCING SAID MODEL AND USE THEREOF - A vascular model includes at least one microchannel perfusable by at least one fluid and in a form of a hollow structure having a wall thickness in a range from 0.1 μm to 1000 μm, a concave inner surface with a cross-section which is circular in part and at least one pore having a diameter in a range from 1 nm to 100 μm. The at least one microchannel has a width in a range from 0.01 μm to 10 mm and a depth in a range from 0.01 μm to 10 mm. At least one chamber is perfusable by a same and/or different fluid and surrounds the at least one microchannel over an entire length and width or over parts thereof. The at least one chamber adjoins the at least one microchannel. At least one connector is configured to receive and/or discharge the at least one fluid. | 12-26-2013 |
Isabella Houweling-Gazzoli, Zoetermeer NL
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20120270930 | METHODS AND COMPOSITIONS FOR DYSFERLIN EXON-SKIPPING - The disclosure provides methods and compositions for inducing exon-skipping in a dysferlin pre-mRNA useful, e.g., in restoring function in a dysferlin deficiency. The disclosure also provides improved methods and compositions for generally inducing exon-skipping in a pre-mRNA. | 10-25-2012 |
Isabella La Fosse-Marin, Cincinnati, OH US
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20150272826 | Blister Cards Promoting Intuitive Dosing - A daily blister card housing a unit dose includes a back side and a front side opposite the back side. The front side includes a manufacturer indicator visible on the front side. A face has an outer periphery and a total planar area bounded by the outer periphery. One or more blisters extend outwardly at the face that contains at least three unit doses that are visible from outside the one or more blisters. Each of the one or more blisters includes a shoulder contacting a cavity backing surface and a projected cavity area bounded by the shoulder that is projected onto the cavity backing surface. A total projected cavity area of the one or more blisters is no more than about 45 percent of the total planar area bounded by the outer periphery. | 10-01-2015 |
Isabella Martin, Waldshut-Tiengen DE
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20140348991 | FLAVOUR GENERATION DURING MICROWAVE HEATING - A process for generating flavours during the microwave heating of food comprising preparing a suspension in oil of a powder comprising one or more compounds having carbonyl and amino groups capable of undergoing a Maillard reaction and/or a caramelisation reaction, the powder having a water activity in the range 0.25 to 0.8, and heating the suspension of powder in oil in a microwave oven for a time sufficient to generate the flavours. | 11-27-2014 |
Isabella Modonesi, De Bilt NL
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20090041153 | MIMO RECEIVERS HAVING ONE OR MORE ADDITIONAL RECEIVE PATHS - In a multiple-input, multiple-output (MIMO) system, a receiver is implemented with at least one additional receive path beyond the number of transmit antennas used to transmit the signals (e.g., wireless OFDM signals) received at the receiver. In one embodiment, the additional receive path is used to reduced co-channel interference (CCI) in the recovered OFDM signals. In particular, each receive path applies recursive filtering to generate separate subcarrier signals. A processor converts the separate subcarrier signals from the different receive paths into a first set of subcarrier signals corresponding to each transmitted OFDM signal, where each first set of subcarrier signals has desired signal and possibly CCI. The processor also generates a second set of subcarrier signals corresponding to the CCI. The processor subtracts portions of the second set of subcarrier signals from each first set of subcarrier signals to generate recovered OFDM signals having reduced CCI. | 02-12-2009 |
Isabella Pallavicini, Briosco (milan) IT
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20090202550 | MONOCLONAL ANTIBODIES AND IMMUNODETECTION ASSAY SPECIFIC FOR THE CHEMOTACTIC EPITOPE OF THE UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR - The present invention describes monoclonal antibodies specific for the chemotactic epitope of the uPAR. In particular, the invention comprises monoclonal antibodies against uPAR fragments specifically recognizing in whole or in part the chemotactic sequence of uPAR connecting domain 1 to domain 2. | 08-13-2009 |
Isabella Roncagliolo, Genoa IT
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20100082817 | METHOD OF DISPATCHING APPLICATION MESSAGES - A method for dispatching a plurality of messages incoming into a dispatching server, each incoming message being issued by a source application and targeted to at least a destination application, the source application, the destination application and the dispatching server residing within a server-client network. The method includes the steps of defining a maximum rate of incoming messages per second, choosing an appropriate message rate reduction policy out of a first and of a second message rate reduction policy, starting a process which periodically determines a current rate of incoming messages per second, dispatching the message in case the current rate is smaller than the maximum rate, activating the appropriate message rate reduction policy in case the current rate of incoming messages is higher than the maximum rate, monitoring a result of the process and adapting a totality of parameters for the appropriate message rate reduction in case the current rate of incoming messages has dropped below the maximum rate. | 04-01-2010 |
Isabella Rotberg, Boynton Beach, FL US
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20130251865 | Antioxidant Formulations - Antioxidant formulations containing new active molecules with tocopherols are disclosed. The best performing formulas contain extracts of green tea that are oil soluble, extracts of rosemary, extracts of spearmint and tocotrienols. Interestingly, the amount of tocopherols in formulas could be reduced by 50% in this diet when the other actives were increased accordingly. | 09-26-2013 |
Isabella Siepe, Dossenheim DE
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20150257383 | METHOD FOR COMBATING PHYTOPATHOGENIC HARMFUL MICROBES ON CULTIVATED PLANTS OR PLANT PROPAGATION MATERIAL - The present invention relates to a method for combating phytopathogenic harmful microbes on cultivated plants or plant propagation material comprising applying an oligomer formed by polymerizing aminoalkyl (meth)acrylate or aminoalkyl (meth)acrylamide monomers or its agrochemically acceptable salts. According to another aspect the present invention relates to a post-harvest treatment method for the suppression of biological infestation in harvested produce comprising applying an oligomer according to the invention to the harvested produce. | 09-17-2015 |
Isabella Tai, Vancouver CA
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20100272643 | Procaspase 8-Mediated Disease Targeting - The invention provides compositions and method for delivering a therapeutic or diagnostic agent to a disease site in a mammal, the method comprising administering to the mammal a therapeutically or diagnostically effective amount of a pharmaceutical composition, wherein the pharmaceutical composition comprises the therapeutic or diagnostic agent coupled to a Procaspase 8 polypeptide and a pharmaceutically acceptable carrier. | 10-28-2010 |
20100286058 | Assessing Chemotherapy Resistance of Colorectal Tumors by Determining Sparc Hypermethylation - Hypermethylation of the SPARC promoter is identified as a mechanism for repressing SPARC gene in cancer resulting in resistance to therapy. The restoration of SPARC expression with demethylating agents, such as 5-Aza-2′deoxycytidine, is shown to enhance chemosensitivity. The invention provides a mechanism of limiting the number of patients exposed to toxicity of demethylating agents by targeting its administration to the subset of patients with hypermethylation of the SPARC promoter. | 11-11-2010 |
20140363377 | PROCASPASE 8-MEDIATED DISEASE TARGETING - The invention provides compositions and method for delivering a therapeutic or diagnostic agent to a disease site in a mammal, the method comprising administering to the mammal a therapeutically or diagnostically effective amount of a pharmaceutical composition, wherein the pharmaceutical composition comprises the therapeutic or diagnostic agent coupled to a Procaspase 8 polypeptide and a pharmaceutically acceptable carrier. | 12-11-2014 |
Isabella Ulrich-Brehm, Ratingen DE
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20130071343 | QUATERNARY DIALKANOLAMINE ESTERS - The invention relates to novel quaternary ammonium compounds of the esterquat type, to a method for the production thereof, and to the use thereof in formulations. | 03-21-2013 |
20130078208 | QUATERNARY DIALKANOLAMINE ESTERS - The invention relates to novel quaternary ammonium compounds of the esterquat type, to a method for the production thereof, and to the use thereof in formulations. | 03-28-2013 |
Isabella Verzberger-Epshtein, Stratford CA
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20130131183 | METHODS AND COMPOSITIONS FOR IMPROVING THE HEALTH OF ANIMALS - The invention features compositions and methods for the administration of an oxidatively transformed carotenoid, or a fractionated component thereof, for improving the health of animals, such as increasing joint mobility, increasing activity, and improving coat quality. | 05-23-2013 |
Isabella Wulur, Rancho Cucamonga, CA US
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20090269315 | METHODS OF USING ADIPOSE TISSUE-DERIVED CELLS IN THE TREATMENT OF CARDIOVASCULAR CONDITIONS - Cells present in processed lipoaspirate tissue are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit. | 10-29-2009 |
20120264200 | SYSTEMS AND METHODS FOR ISOLATING AND USING CLINICALLY SAFE ADIPOSE DERIVED REGENERATIVE CELLS - Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject. | 10-18-2012 |
20150152375 | SYSTEMS AND METHODS FOR ISOLATING AND USING CLINICALLY SAFE ADIPOSE DERIVED REGENERATIVE CELLS - Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject. | 06-04-2015 |
Isabella Wulur, West Hills, CA US
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20100136668 | SYSTEMS AND METHODS FOR ISOLATING AND USING CLINICALLY SAFE ADIPOSE DERIVED REGENERATIVE CELLS - Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject. | 06-03-2010 |
Isabella Zama, Faenza IT
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20120171113 | PROCESS FOR THE PREPARATION OF TITANIUM DIOXIDE HAVING NANOMETRIC DIMENSIONS AND CONTROLLED SHAPE - The present invention relates to a process for the preparation of materials with nanometric dimensions and controlled shape, based on titanium dioxide. The invention also relates to a process for the preparation of titanium dioxide nanorods and nanocubes with anatase phase composition, which are highly suitable for photocatalytic use, in particular for applications involving photovoltaic cells, for example Dye Sensitized Solar Cells (DSSC), photoelectrolysis cells and tandem cells for the conversion of solar energy and the production of hydrogen. | 07-05-2012 |