Patent application number | Description | Published |
20110237000 | Method for detecting an analyte molecule - The invention relates to a method for detecting the presence or amount of an analyte, said method comprising (a) coupling the analyte to a carrier molecule, wherein the carrier molecule is larger in size, electrically charged and/or polar, to form an analyte:carrier molecule complex; (b) contacting the analyte:carrier molecule complex of (a) with an analyte-binding molecule coupled to a semiconducting nanostructure; and (c) determining the change in conductance upon binding of the analyte:carrier molecule complex to the analyte-binding molecule and correlating the determined change in conductance to the presence or amount of the analyte. Alternatively, the analyte:carrier molecule complex of (a) is immobilized on the nanostructure and the immobilized analyte:carrier molecule complex is contacted with the analyte-binding molecule. | 09-29-2011 |
20120143228 | ADHESIVE STRUCTURE WITH STIFF PROTRUSIONS ON ADHESIVE SURFACE - A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young's modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion. | 06-07-2012 |
20120251611 | SUPER-HYDROPHILIC STRUCTURES - A polydioxanone film comprising substantially cylindrical polydioxanone pillars on at least one side thereof, said pillars having diameters from about 0.2 μm to about 3 μm, and heights from about 2 μm to about 20 μm from the surface of the film, a process for adsorbing proteins using the film and medical devices incorporating the film. | 10-04-2012 |
20120280284 | MICRO-FLUIDIC ELECTRONIC DEVICES AND METHOD FOR PRODUCING SUCH DEVICES - A micro-fluidic electronic device includes a micro-fluidic component and an electronic component formed on a sheet of paper. An electrically-active layer of the electronic component, such as a nano-material layer, interacts with a fluid sample deposited within a fluid reservoir of the component, and changes the electronic properties of the electronic component. This can be detected by passing an electrical signal through the electronic component. The micro-fluidic electronic device can be formed straightforwardly and inexpensively by printing or mold-casting. | 11-08-2012 |
20120302427 | POLYMERIC STRUCTURES FOR ADSORBING BIOLOGICAL MATERIAL AND THEIR METHOD OF PREPARATION - A biologic-adsorbent, e.g., protein-adsorbent, material is prepared by forming a polymeric substrate into structures having high surface area topography whose biologic adsorbing properties can be controlled. Biologic adsorption by these structures of optimized high surface area topography is increased by mild treating of the surfaces, e.g., by oxygen plasma, without substantially altering topography. Structures can have tailored geometric features including microstructures, e.g., pillars, with a diameter from 100 nm-50 μm and height greater than 1 μm. | 11-29-2012 |
20120302465 | POLYMERIC STRUCTURES FOR ADSORBING BIOLOGICAL MATERIAL AND THEIR METHOD OF PREPARATION - A biologic-adsorbent, e.g., protein-adsorbent, material is prepared by forming a polymeric substrate into structures having high surface area topography whose biologic adsorbing properties can be controlled. Biologic adsorption by these structures of optimized high surface area topography is increased by mild treating of the surfaces, e.g., by oxygen plasma, without substantially altering topography. Structures can have tailored geometric features including microstructures, e.g., pillars, with a diameter from 100 nm-50 μm and height greater than 1 μm. | 11-29-2012 |
20130172927 | ADHESIVE STRUCTURE WITH TISSUE PIERCING PROTRUSIONS ON ITS SURFACE - An implant having an adhesive structure comprising a planar surface having two sides and rectangular cuboid-based protrusions having pyramidal tips extending from at least one of said sides, optionally having a porous basic supporting structure, and methods of making and using such implants. | 07-04-2013 |
20130206330 | ADHESIVE STRUCTURE WITH STIFF PROTRUSIONS ON ADHESIVE SURFACE - A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young's modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion. | 08-15-2013 |
20130266761 | SUPER-HYDROPHOBIC HIERARCHICAL STRUCTURES, METHOD OF FORMING THEM AND MEDICAL DEVICES INCORPORATING THEM - Synthetic polymer substrates comprising a hierarchical surface structure of multiple domes and multiple pillars on said domes, wherein said substrate is a synthetic polymer film, said domes have diameters in the range from about 5 μm to about 400 μm, heights in the range from about 2.5 μm and about 500 μm, and said pillars have diameters in the range from about 20 nm to about 5 μm and aspect ratios of from about 2 to about 50, and methods of making and using them. | 10-10-2013 |
20130267880 | BLOOD CLOTTING SUBSTRATE AND MEDICAL DEVICE - A blood clotting substrate and device which has a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film. | 10-10-2013 |
20130288225 | METHOD FOR SEPARATING WHOLE BLOOD - A method of separating blood by providing a horizontal substrate having a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film, depositing a whole blood sample on an upper surface of the substrate, collecting red blood cells on the upper surface of the pillars and permitting remaining components of said whole blood sample to flow downward and through the pillars. | 10-31-2013 |