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Irving Weinberg

Irving Weinberg, Bethesda, MD US

Patent application numberDescriptionPublished
20090305223METHOD AND APPARATUS FOR EVALUATIING INTERACTIONS IN ISOLATED TISSUE - An apparatus for evaluating the effects of stimuli on tissue includes an environment for holding at least a sample of the tissue from a living person. The apparatus also has a first source connected to the environment for delivering nutrients to the tissue to maintain the tissue in a viable condition for more than one week. A second source is connected to the environment for delivering a biologically active agent to the tissue. The biologically active agent is capable of inducing carcinogenesis in the tissue when metabolized. An effluent outlet is connected to the environment to remove effluent from the environment.12-10-2009
20100036261METHOD AND DEVICE FOR IMAGE GUIDED SURGERY - A fluorometer includes a light source to generate excitatory light toward a tissue, the tissue generating fluorescent light in response to the excitatory light. The fluorometer also includes a light sensor to receive the fluorescent light and generate a digital signal. A processor is connected to the light sensor to receive the digital signal and generate a digital image, and a display displays the digital image. The tissue generates fluorescent light as a result of excitation of at least one intrinsic tissue metabolic product. A method for distinguishing between viable and non-viable tissue using the fluorometer also is described.02-11-2010
20110070157RADIOMETAL-LABELED AMINO ACID ANALOGS, IMAGING AND THERAPEUTIC AGENTS INCORPORATING THE SAME, AND METHODS USING THE SAME - An amino acid analog is provided, in syn-stereoisomeric form, anti-stereoisomeric form, or a combination thereof. The amino acid analog includes a cyclobutane ring with at least one of an amine group and a carboxyl group attached to one carbon node of the cyclobutane ring. A chain of moieties X, Y, and Z attached to one of remaining three carbon nodes of the cyclobutane ring. X is a chelating agent selected from a group comprising DCTA, DOTA, DTPA, EDTA, NOTA, PCTA, and TETA. Y is a linking moiety selected from a group comprising —NH—CO— and —NH-p-CHSN-Bn- where the linking moiety facilitates incorporation of the chelating agent into the amino acid analog. Z is a metal radioisotope selected from a group comprising Cu-60, Cu-61, Cu-62, Cu-64, Cu-67, Ga-67, Ga-68, Y-86, Y-88, Y-90, Sr-85, Sr-89, Gd-153, Gd-157, Sm-153, Lu-177, W-185, Re-186, Re-188, and Ir-192.03-24-2011
20110089947APPARATUS AND METHOD FOR DECREASING BIO-EFFECTS OF MAGNETIC GRADIENT FIELD GRADIENTS - A magnetic field generator includes a power source and a segmented or un-segmented coil connected to the power source to generate a time-varying magnetic field. Energy is applied to the coil so that the coil generates a time-varying magnetic field gradient with a magnitude of at least 1 milliTesla per meter and a rise-time of less than 10 microseconds. The coil may be comprised of overlapping, non-overlapping or partially overlapping coil segments that may individually energized to further improve the operating characteristics of the coil to further decrease bio-effects in magnetic resonance imaging through the use of reduced pulse lengths and multi-phasic magnetic gradient pulses.04-21-2011
20110096966METHOD AND APPARATUS FOR DETECTING BONE VARIABILITY WITH ULTRAVIOLET LIGHT - A method and apparatus for assessing the time since demise of one or more tissue components, comprising a source of radiation to generate excitatory radiation toward a tissue component, the tissue component generating responsive radiation in response to the excitatory radiation, a sensor to receive the responsive radiation from the tissue component and create a signal indicating the rate of change (over time) of the responsive radiation, a processor connected to the sensor to receive the signal from the sensor, and wherein the processor evaluates the received signal and provides information whereby a user can assess the time since demise of the tissue component based on responsive radiation generated by the tissue component as a result of excitation of at least one intrinsic tissue component metabolic product.04-28-2011

Patent applications by Irving Weinberg, Bethesda, MD US

Irving Weinberg, Besthesda, MD US

Patent application numberDescriptionPublished
20090315560APPARATUS AND METHOD FOR DECREASING BIO-EFFECTS OF MAGNETIC GRADIENT FIELD GRADIENTS - A magnetic field generator includes a power source and a coil connected to the power source to generate a time-varying magnetic field. Energy is applied to the coil so that the coil generates a time-varying magnetic field gradient with a magnitude of at least 1 milliTesla per meter and a rise-time of less than 10 microseconds. One or more of a capacitor, a multi-stage high-voltage switch, and/or a pulse-forming network may assist with the generation of the magnetic field gradient.12-24-2009
20100016932APPARATUS AND METHOD FOR INTERNAL HYPOTHERMIC RADIOPROTECTION - A radioprotection device includes a body positionable in a living organism adjacent to both healthy and unhealthy tissue, where the living organism has a predetermined body temperature. The device includes a cooling element disposed within the body. The cooling element permits cooling of the healthy tissue adjacent to the body to a protective temperature greater than 0° C. and less than the predetermined body temperature during a therapeutic time period during which radiation is applied to the unhealthy tissue. The body discourages cooling of the unhealthy tissue to the protective temperature during the therapeutic time period, thereby providing greater radioprotection to the healthy tissue than the unhealthy tissue during the therapeutic time period.01-21-2010
20110068791ULTRA-FAST PRE-POLARIZING MAGNETIC RESONANCE IMAGING METHOD AND SYSTEM - A method and apparatus generate a pre-polarizing magnetic field having a rise-time of less than about 10 microseconds and/or a fall-time of less than about 10 microseconds for immersing a tissue sample in the pre-polarized magnetic field to polarize an animal tissue sample whereby magnetic gradient and/or radio-frequency pulses may be applied in order to read out the location and/or state of the spins. A method and apparatus deliver such magnetic fields through planar coils. A method and apparatus enable guidance and propulsion of magnetic fluids.03-24-2011

Patent applications by Irving Weinberg, Besthesda, MD US