Irina G.
Irina G. Kazakova, Los Gatos, CA US
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20090118139 | Microfluidic method and system for enzyme inhibition activity screening - Methods for screening a compound for enzyme inhibition activity include providing at least one sample mixture to a microfluidic device, applying vacuum pressure to the sample mixture, flowing the sample mixture along a microchannel of the microfluidic device, separating at least two components of the sample mixture based upon a net charge difference between the product and at least one other material to produce separated material, detecting at least one of the separated materials, and determining enzyme inhibition activity based on the detection of the separated material. Kits for screening a compound for enzyme inhibition activity include a first multiwell plate having a specific plurality of enzymes disposed within a first plurality of wells and a second multiwell plate having a plurality of enzyme substrates disposed with a second plurality of wells, a phosphate source and a cofactor disposed within each well of the second plate. | 05-07-2009 |
20110024296 | Analyte Injection System - This invention provides methods and systems for injection of analytes into a separation channel for resolution and detection. Samples can be preconditioned and concentrated by isotachophoresis (ITP) before the injection is triggered by a detected voltage event. Separation of analytes from other sample constituents can be enhanced using skewing channel ITP. | 02-03-2011 |
Irina G. Luzina, Ellicott City, MD US
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20090131359 | ANTIFIBROTIC THERAPY - The present invention relates to methods of treating severe or rapidly progressing pulmonary fibrosis in a subject in need of a treatment thereof. The methods comprise increasing the activity of pulmonary and activation-regulated chemokine (CCL18) in the lungs of the subject, whereby increasing CCL18 activity modulates the activity of at least one antifibrotic factor in the lungs of the subject. The present invention also relates to methods of screening test procedures that may be capable of treating severe or rapidly progressing pulmonary fibrosis. | 05-21-2009 |
Irina G. Schwenderman, Wexford, PA US
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20110070374 | POLYCARBODIIMIDES - Polycarbodiimides, processes for their preparation, water-borne coating compositions and the use of the water-borne coating compositions to coat flexible substrates such as leather, artificial leather, textile fabrics, fibers and non-wovens that are used in the manufacture of athletic footwear are disclosed. | 03-24-2011 |