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Irene

Irene Agerkvist, Danderyd SE

Patent application numberDescriptionPublished
20110178019NEW PROTECTING COMPOSITIONS FOR RECOMBINANTLY PRODUCED FACTOR VIII - A histidine-free composition comprising: 07-21-2011

Irene Aguilera Bonet, Madrid ES

Patent application numberDescriptionPublished
20100206351PHOTONIC USE OF INTERMEDIATE BAND MATERIALS ON A CHALCOGENIDE-TYPE SEMICONDUCTOR - The invention relates to the use, in the manufacturing of materials or devices for photonic applications, of chalcogenide-type compounds having an octahedrally coordinated indium element and wherein a transition element is introduced in octahedral position generating a partially occupied intermediate band separate from those of valence and conduction of the initial semiconductor, according to quantum mechanics calculations. This enables, by absorption of two photons having energy lower than the prohibited bandwidth of the initial semiconductor, a result equivalent to that achieved, without said intermediate band, by the absorption of a higher-energy photon. The use of such a material can thereby improve yield and performance of various photovoltaic, photocatalytic, photoelectrochemical, optoelectronic or photonic conversion devices. Indium sulfide substituted in part with vanadium or titanium is one of the specific materials having these properties that is synthesised according to the invention.08-19-2010

Irene Andruszkiewicz, San Diego, CA US

Patent application numberDescriptionPublished
20090170110COMPOSITIONS AND METHODS TO DETECT CANDIDA ALBICANS NUCLEIC ACID - Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for 07-02-2009
20090305293COMPOSITIONS AND METHODS TO DETECT CANDIDA ALBICANS NUCLEIC ACID - Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for 12-10-2009
20100159530COMPOSITIONS AND METHODS TO DETECT CANDIDA ALBICANS NUCLEIC ACID - Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for 06-24-2010
20100286383COMPOSITIONS TO DETECT CANDIDA ALBICANS NUCLEIC ACID - Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for 11-11-2010

Irene Bozzoni, Roma IT

Patent application numberDescriptionPublished
20110009468MIRNA, SIRNA AND USE THEREOF IN THERAPY - The present invention relates to a mixture of molecules comprising at least one miRNA and at least one siRNA, or at least two miRNAs, or at least two siRNAs for inducing hematopoietic differentiation or for treating leukemia wherein the miRNA is able to modulate hematopoietic differentiation and/or to act as oncosuppressor, and the siRNA is able to modulate hematopoietic differentiation or to inhibit the expression of a fusion product deriving from a chromosomic translocation associated to leukemia.01-13-2011

Irene Bozzoni, Rome IT

Patent application numberDescriptionPublished
20110301218MODIFIED snRNAs FOR USE IN THERAPY - The invention relates to a nucleic acid encoding a small nuclear RNA (snRNA), which snRNA is modified so that it contains sequence capable of hybridizing with the 5′ and 3′ splice site junctions and an exonic splicing enhancer of an exon of a pre-mRNA, so that the exon sequence is skipped during the splicing process that converts the pre-mRNA in the mature mRNA. The nucleic acid, the modified snRNA and vectors incorporating the nucleic acid may be used in the therapy, in particular in the treatment of muscular dystrophies.12-08-2011

Irene Bramke, New Milton GB

Patent application numberDescriptionPublished
20110104754CELL CULTURE MEDIUM - We describe a method of growing an animal cell in a culture medium, in which the culture medium comprises an elevated concentration of a thymidine family member, in which the growth or viability of the animal cell is increased as a result of the elevated concentration of the thymidine family member in the cell culture medium. Preferably, the cell culture medium comprises a semi-solid medium, which is a serum free or chemically defined medium.05-05-2011

Irene Campristron, Le Mans FR

Patent application numberDescriptionPublished
20110268689PHOTO-CROSSLINKABLE ANTIFOULING COMPOSITIONS, FILMS OBTAINED FROM SAID COMPOSITIONS, AND CORRESPONDING USES - Photo-crosslinkable antifouling compositions, in particular antibacterial, antifungal and anti-algae ones, which include the combination of at least one telechelic oligoisoprene of a particular formula with an agent for crosslinking the oligoisoprene. The antifouling film is obtained by applying a thin layer of such a liquid composition on a substrate and is crosslinked at room temperature by exposure to visible and/or UV radiations. The film can be used for preventing the occurrence of a biofilm on any surface in a humid or aqueous environment, and can be used as an additive for preparing materials with a view to imparting bacteriostatic and/or bactericidal properties thereto.11-03-2011

Irene Casalprim Castella, Barcelona ES

Patent application numberDescriptionPublished
20090124577Intermediate Compounds for the Preparation of an Angiotensin II Receptor Antagonist - It comprises new substituted 4-valinylmethylphenyl boronic acids of formula (II) and their derivatives and also its preparation process. It also comprises a preparation process of Valsartan (I) from such intermediates. The process comprises the reaction of the new 4-valinylmethylphenyl boronic compounds with a (halophenyl)tetrazole compound which proceeds with high yields. The process is particularly advantageous in its practical industrial realization because it avoids the use of azide derivatives and also the use of expensive biphenyl intermediates.05-14-2009

Irene Cecchini, Rome IT

Patent application numberDescriptionPublished
20090311732ANALYTICAL METHOD FOR ANALYZING C-TERMINUS TRUNCATION - This invention relates to analytical methods for quantification of truncation at the C-terminus of an Fc-containing protein.12-17-2009

Irene Dris, Clifton Park, NY US

Patent application numberDescriptionPublished
20100048853POLYETHERIMIDE POLYMER FOR USE AS A HIGH HEAT FIBER MATERIAL - Various embodiments of polymer fibers comprising a high heat polymer and process for making the polymer fibers are provided. In one embodiment, synthetic polymer fibers comprise polyetherimide polymer that is substantially free of foreign particulate matter greater than about 100 microns in size. A process for producing polymer fiber includes melting polymer comprising polyetherimide to a melt temperature that ranges from about 180-500° C. to form a molten polymer; passing the polyetherimide that is substantially free of foreign particulate matter above about 100 microns in size, through a spinneret comprising a plurality of hole openings to produce a fiber bundle; and cooling the fiber bundle with a cooling medium having a temperature that ranges from about 0° C. to about 80° C.02-25-2010

Patent applications by Irene Dris, Clifton Park, NY US

Irene Dris, Raritan, NJ US

Patent application numberDescriptionPublished
20090110845METHODS FOR BONDING HIGH TEMPERATURE SENSORS - The invention provides a method of bonding a sensor to a surface comprising the steps of applying a thermoplastic film to a first surface of the sensor. The first surface of the sensor is contacted with a surface of an object to be monitored, wherein the composition effectively bonds the sensor to the object surface at a temperature up to approximately 250° C. The invention also provides a method of bonding a sensor to a surface comprising the steps of applying a thermoplastic film to a surface area of an object to be monitored. The first surface of a sensor is contacted with the object surface area, wherein the film effectively bonds the sensor to the object surface at a temperature up to approximately 250° C.04-30-2009

Irene Eijgendaal, Weesp NL

Patent application numberDescriptionPublished
20110200687BIFEPRUNOX MESYLATE MAINTENANCE DOSE COMPOSITIONS AND METHODS FOR USING THE SAME - The present disclosure provides novel pharmaceutical dosage forms such as a maintenance treatment dose and methods for making the same, and methods for using said compounds and maintenance treatment doses to treat and prevent diseases and/or disorders.08-18-2011

Irene Eijgendaal, Cp Weesp NL

Patent application numberDescriptionPublished
20080286258Bifeprunox mesylate maintenance dose compositions and methods for using the same - The present disclosure provides novel pharmaceutical dosage forms such as a maintenance treatment dose and methods for making the same, and methods for using said compounds and maintenance treatment doses to treat and prevent diseases and/or disorders.11-20-2008

Irene Ferrari Epouse Gosset, Saint Vincent De Mercuze FR

Patent application numberDescriptionPublished
20090112328SHOULDER OR HIP PROSTHESIS AND METHOD FOR SETTING SAME - A prosthesis and method for a ball and socket joint. The prosthesis includes a first component including an anchoring shank and a metaphyseal portion. The metaphyseal portion includes a first articular surface configured to move in translation relative to the anchoring shank. An intermediate component includes a first articular surface configured to engage with the first articular surface on the metaphyseal portion, and a second articular surface configured to engage with the ball and socket joint.04-30-2009

Irene Gallici, Precenicco IT

Patent application numberDescriptionPublished
20100326290COOKING OVEN COMPRISING EXHAUST GAS PURIFICATION ASSEMBLY - A cooking oven comprising a cooking cavity and an exhaust gas purification assembly comprising a self-heated filter element comprising a gas-permeable, electrically conductive silicon carbide material and a current supply structure operable for self-heating said filter element. Preferably, said purification assembly comprises a self-heated filter element comprised of a foamed silicon carbide structural element.12-30-2010

Irene Gander-Meisterernst, Stockdorf DE

Patent application numberDescriptionPublished
20110009481MEDICAMENT FOR THE TREATMENT OF VIRAL SKIN AND TUMOUR DISEASES - The invention relates to a medicament containing a compound of general formula (I), where R01-13-2011

Irene Gascón, Madrid ES

Patent application numberDescriptionPublished
20100022623Methods and Compositions for the Treatment of Eye Disorders with Increased Intraocular Pressure - The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention.01-28-2010
20100317720Methods and Compositions for the Treatment of Intestinal Conditions - Methods and compositions for the treatment of intestinal disorders, such as IBD and Crohn's disease, are disclosed. Preferred compositions include siNA. Also disclosed is a method of specifically targeting siNA to treat intestinal disorders by intrarectal administration of siNA compounds.12-16-2010
20100331394Methods and Compositions for the Treatment of Eye Disorders with Increased Intraocular Pressure - The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention.12-30-2010
20110313016Treatment of Intestinal Conditions - Methods and compositions for the treatment of intestinal disorders, such as IBD and Crohn's disease, are disclosed. Preferred compositions include siNA. Also disclosed is a method of specifically targeting siNA to treat intestinal disorders by intrarectal administration of siNA compounds.12-22-2011

Irene Ginis, Beit Shemesh IL

Patent application numberDescriptionPublished
20120058156ACTIVATED LEUKOCYTE COMPOSITION AND USES FOR WOUND HEALING - Disclosed are therapeutic, blood-derived activated leukocyte compositions, methods of making them, and methods of using the compositions to repair or promote the prevention and healing of wounds.03-08-2012

Irene Gitin, Sunnyvale, CA US

Patent application numberDescriptionPublished
20110055115ROTH-AWARE FINANCIAL ADVISORY PLATFORM - A financial advisory platform that includes Roth contribution support is provided. According to one embodiment, trade-offs between a current retirement savings strategy and an alternative retirement savings strategy are presented to an end user. Information is received regarding the alternative retirement savings strategy, which includes information regarding a target proportion of retirement plan contributions to be invested pre-tax and post-tax in a retirement portfolio where the target proportion is different than the current proportion of pre-tax and post-tax contributions under the current retirement savings strategy. An after tax value of the retirement portfolio is forecast by a forecasting module based on the alternative retirement savings strategy. Trade-offs are presented between the alternative retirement savings strategy and the current retirement savings strategy. The trade-offs include an indication regarding an effect on take-home pay as a result of switching from the current retirement savings strategy to the alternative retirement savings strategy.03-03-2011
20120005124ROTH-AWARE FINANCIAL ADVISORY PLATFORM - A financial advisory platform that includes Roth contribution support is provided. According to one embodiment, a method is provided for identifying an alternative retirement savings strategy that maintains take-home pay and increases a forecasted after tax value of a retirement portfolio. A split optimization module determines whether there exists an alternative retirement savings strategy for an investor that both (i) maintains take-home pay of an investor and (ii) increases a forecasted after tax value of a retirement portfolio of the investor as compared to a current retirement savings strategy of the investor. If the alternative retirement savings strategy exists, then a user interface module presents information associated with the alternative retirement savings strategy, including information regarding a recommended periodic contribution by the investor to be invested in the retirement portfolio and information regarding a target proportion of the recommended periodic contribution that should be made pre-tax and post-tax.01-05-2012

Irene Griswold-Prenner, San Francisco, CA US

Patent application numberDescriptionPublished
20080300206Alpha-Synuclein Kinase - The invention provides agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient. Preferred agents include inhibitors of PLK2 kinase.12-04-2008
20090220505METHODS OF INHIBITING AMYLOID TOXICITY - The present invention features methods and compositions for inhibiting amyloidogenic protein toxicity, inhibiting formation of an amyloidogenic protein deposit and/or treating amyloidogenic diseases by administering a pharmaceutically effective amount of one or more agents that bind an integrin or an integrin subunit.09-03-2009
20100143946ALPHA-SYNUCLEIN KINASE - The invention provides agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient. Preferred agents include inhibitors of PLK2 kinase.06-10-2010
20100303824SIGNALING INTERMEDIATES IN AN IN VITRO MODEL OF ALZHEIMER'S DISEASE - The invention provides a novel human protein, FISH adaptor protein, involved in amyloid β-protein-mediated cell death. Also provided are methods for modulating amyloid β-protein-mediated cell death using agents that interfere with the activity of FISH adaptor protein.12-02-2010
20110207796ALPHA-SYNUCLEIN KINASE - Agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient are provided. Preferred agents include inhibitors of PLK2 kinase.08-25-2011

Patent applications by Irene Griswold-Prenner, San Francisco, CA US

Irene Hoste Ventos, Tournefeuille FR

Patent application numberDescriptionPublished
20100036551METHOD AND DEVICE FOR ASSISTING AN AIRCRAFT FLIGHT CONTROL DURING LANDING APPROACH - The inventive flight control assisting device comprises first means (02-11-2010

Irene Ingegneri, Lodi IT

Patent application numberDescriptionPublished
20100226865TOOTHPASTE COMPOSITION - A toothpaste composition comprising a surfactant, an abrasive, a humectant, triglyceride oil, a carboxylated polysaccharide, and a sulphated or sulphonated polysaccharide and the use of a sulphated or sulphonated polysaccharide, in particular a carrageenan, to improve the in-use foam quality of a toothpaste.09-09-2010

Irene Ivashenko, Los Altos, CA US

Patent application numberDescriptionPublished
20110145284PRESENTING SKILLS DISTRIBUTION DATA FOR A BUSINESS ENTERPRISE - Systems and techniques to present graphical representations of skill needs versus skill availability in a business organization. Skill needs and skill availability across multiple categories can be represented as geometric objects that overlap on a two-dimensional chart. Overlapping of the geometric objects indicates one or more relationships between skill needs and skill availability across an arbitrary number of dimensions that correspond to defined categories. The categories, and thus the number and meaning of axes in the chart, can be dynamically selected, thereby providing a tool to quickly identify staffing shortfalls and overcapacity.06-16-2011

Irene Jennrich, Winnenden DE

Patent application numberDescriptionPublished
20100261822MODIFIED REACTION RESIN - The object of the patent is to provide a modified reaction resin, comprising: a) at least one cyanate tester; b) at least one polyorganosiloxane contained in the reaction resin in finely distributed form. The thus modified reaction resin is stable for storage for long periods in non-cured form and can be cured to form duromers with advantageous mechanical characteristics.10-14-2010
20110003946CURABLE REACTION RESIN SYSTEM - A curable reaction resin system is described, which is to be processed as a two-component mass and which contains a resin component, a curing agent as well as polymer particles that are dispersed in the resin component, the polymer particles being contained in the reaction resin system at a proportion of more than 25 and up to 50 wt. %.01-06-2011
20110124811CURABLE REACTION RESIN SYSTEM - A curable reaction resin system can be used for example as a casting compound, molding compound, or high-temperature resin, and is to be processed as a two-component compound. The system has a first reaction resin component and a second reaction resin component, the first reaction resin component being epoxy-free and realized on the basis of a cyanate ester.05-26-2011
20110221308METHOD FOR GLUING COMPONENTS, FORMING A TEMPERATURE-RESISTANT ADHESIVE LAYER - A method for gluing components is provided, forming an adhesive layer which is capable of functioning, at least in a temperature range of ≧100° C. to ≦160° C., wherein the adhesive layer is obtained from a curable reactive resin system. The reactive resin system includes an epoxy resin component and polymer particles dispersed in the epoxy resin component, the dispersed polymer particles furthermore including addition-crosslinked silicone elastomer. Also provided is the use of a reactive resin system for gluing piezoelectric ceramics and/or permanent magnets including rare earth elements and a component configuration including a piezoelectric ceramic, an impedance matching layer and an adhesive layer in contact with the piezoelectric ceramic and the impedance matching layer.09-15-2011

Patent applications by Irene Jennrich, Winnenden DE

Irene Kazhdan, San Antonio, TX US

Patent application numberDescriptionPublished
20090163431COMPOSITIONS AND METHODS FOR MODULATION OF PDX-1 - Methods and compositions for inhibiting PDX-1 are provided according to the present invention. An anti-PDX-1 agent included in inventive methods and compositions includes an antibody, an aptamer, an antisense oligonucleotide, a ribozyme and/or an inhibitory compound. Methods of inhibiting PDX-1 expression in a tumor cell are provided by the present invention which include contacting a tumor cell with an effective amount of an anti-PDX-06-25-2009

Patent applications by Irene Kazhdan, San Antonio, TX US

Irene Knuesel, Zurich CH

Patent application numberDescriptionPublished
20080299104METHODS FOR DETECTING AGENTS INVOLVED IN NEURONAL APOPTOSIS AND COMPOSITIONS THEREOF - The invention provides methods of detecting and identifying agents which moduclate the expression or activity of synGAP, a brain-specific Ras/Rap GTPase activating protein. In vivo studies using knock-out and conditional knock-out transgenic animals show that the level of apoptosis in neurons correlates inversely with the level of synGAP protein, indicating that neuronal apoptosis is enhanced by reduction of synGAP. The invention also describes that synGAP is capable of modulating signal transduction pathways associated with the NMDA receptor and triggering apoptosis, including activation of Ras-GAP. Phosphorylation of synGAP by CaMKII increases its Ras GTPase-activating activity by about 70-95%. Moreover, when these and other phosphorylation sites in the synGAP carboxyl tail are mutated, stimulation of GAP activity after phosphorylation is reduced to about 21±5% as compared to about 70-95% for the wild type protein. Also, phosphosite-specific antibodies used to determine levels of synGAP phosphorylation are described herein.12-04-2008

Irene Kubitza, Berlin DE

Patent application numberDescriptionPublished
20080200360Aqueous Solution and Method for Removing Ionic Contaminants from the Surface of a Workpiece - To reduce ionic contaminants on printed circuit boards that are at least partially covered with a solder resist mask and are provided with top layers on the copper structures, an aqueous cleaning solution is used, which contains at least one ethanolamine compound and/or the salt thereof, at least one alcoholic solvent and, at need, at least one guanidine compound and/or the salt thereof.08-21-2008

Irene Kucharewicz Ropiak, Lawrenceville, NJ US

Patent application numberDescriptionPublished
20090016936IMPROVED CONTAINERS FOR PHARMACEUTICALS, PARTICULARLY FOR USE IN RADIOISOTOPE GENERATORES - The invention is directed to improved containers for pharmaceuticals and any tubing and tubing connectors associated therewith, particularly containers for pharmaceuticals which are irradiated, heated or otherwise subjected to increased pressure. In a preferred embodiment, the invention is directed to an improved container for use in a radioisotope generator, such as a rubidium-82 generator. 01-15-2009
20090129989CONTAINERS FOR PHARMACEUTICALS, PARTICULARLY FOR USE IN RADIOISOTOPE GENERATORS - The invention is directed to improved containers for pharmaceuticals and any tubing and tubing connectors associated therewith, particularly containers for pharmaceuticals which are irradiated, heated or otherwise subjected to increased pressure. In a preferred embodiment, the invention is directed to an improved container for use in a radioisotope generator, such as a rubidium-82 generator.05-21-2009

Irene Lee, Singapore SG

Patent application numberDescriptionPublished
20090202386Alloys, Bulk Metallic Glass, And Methods Of Forming The Same - An alloy having a formula: (Zr1Ti)08-13-2009

Irene Messana, Monserrato IT

Patent application numberDescriptionPublished
20110079076MOLECULAR MARKERS FOR AUTISM - The invention relates to the determination of phosphorylation levels of some specific salivary peptides (statherin, histatin 1, acidic proline-rich proteins, both in whole form (PRP-1 type) and in truncated form (PRP-3 type) as a non-invasive diagnostic marker with a >40% sensitivity for defining autism spectrum disorders (ASDs) patients, methods for performing said determination, a kit for the non-invasive diagnosis of at least 40% of autism cases, containing means for such a determination, and the use of such a determination for therapeutical research on autism.04-07-2011

Irene Michlin, Wendover GB

Patent application numberDescriptionPublished
20110314545METHOD AND SYSTEM FOR AUTOMATIC INVARIANT BYTE SEQUENCE DISCOVERY FOR GENERIC DETECTION - A method for creating a set of genericized signatures for detection of byte sequences in computer code includes accessing a first set of sample signatures, determining a maximum number of wildcards that a wildcarded signature may comprise, determining a first wildcarded signature corresponding to the first set of sample signatures, evaluating the first wildcarded signature, and repeating the steps of evaluating for any second wildcarded signatures. Each of the signatures corresponds to an instance of malware. The evaluation further includes if the number of wildcards in the first wildcarded signature exceeds the maximum number of wildcards, determining a plurality of second wildcarded signatures corresponding to a plurality of subsets of the set of sample signatures. The evaluation further includes if the number of wildcards in the first wildcarded signature is less than or equal to the maximum number of wildcards, adding the first wildcarded signature to a set of genericized signatures.12-22-2011

Irene Mogentale, Lendinara IT

Patent application numberDescriptionPublished
20090190093DUAL SCHEIMPFLUG SYSTEM FOR THREE-DIMENSIONAL ANALYSIS OF AN EYE - An apparatus for imaging an eye can include a pair of Scheimpflug imaging systems. Each Scheimpflug imaging system can have respective video cameras and optics configured to direct light reflected from an eye into the video cameras. The apparatus can also have a movable platform configured to move the pair of Scheimpflug imaging systems in accordance with eye movement detected by an eye tracking imaging system. In some embodiments, the Scheimpflug imaging systems can rotate 90 degrees about an optical axis of an eye being examined.07-30-2009
20100053551METHOD TO REPRESENT IMAGES FOR DISSOCIATIVE STEREOSCOPIC VISION AND RELATED SYSTEM - The following is a method to represent images for dissociative stereoscopic vision, which allows, by means of some simple operations on stereoscopic images, to develop a device comprising a processing card and LCD shuttering goggles, which together with a computer equipped with a graphic card with LVDS output and any image display device, enable to perform visual acuity tests on patients.03-04-2010
20100165293DUAL SCHEIMPFLUG SYSTEM FOR THREE-DIMENSIONAL ANALYSIS OF AN EYE - An apparatus for imaging an eye can include a pair of Scheimpflug imaging systems. Each Scheimpflug imaging system can have respective video cameras and optics configured to direct light reflected from an eye into the video cameras. The apparatus can also have a movable platform configured to move the pair of Scheimpflug imaging systems in accordance with eye movement detected by an eye tracking imaging system. In some embodiments, the Scheimpflug imaging systems can rotate 90 degrees about an optical axis of an eye being examined.07-01-2010

Irene Noguera-Troise, Staten Island, NY US

Patent application numberDescriptionPublished
20100330106Method of Treating Cancer with DLL4 Antagonist and Chemotherapeutic Agent - The invention provides methods for treating various types of cancer/tumor by administering the combination of DII4 antagonists, in particular, DII4 antibodies and fragments thereof that specifically bind human DII4, and chemotherapeutic agents. Such combination therapies exhibit synergistic effects compared to the treatment with either agent alone. Thus, the methods of the invention are particularly beneficial for cancer patients who have low tolerance to the side effects caused by high dosages required for the treatment by either agent alone, by being able to reduce effective dosages. Pharmaceutical compositions and kits containing DII4 antagonists and chemotherapeutic agents are also provided.12-30-2010
20110150905HUMAN ANTIBODIES TO HUMAN DELTA LIKE LIGAND 4 - The present invention provides methods of treating, ameliorating, or inhibiting tumor growth, cancer, or pathological angiogenesis by administering to a subject in need thereof a human antibody or fragment thereof that specifically binds to human delta-like ligand 4 (hDll4) and blocks hDll4 binding to a Notch receptor. The anti-hDll4 antibody or fragment thereof of the present invention have a high affinity with the K06-23-2011

Irene Noguera-Troise, Bay Shore, NY US

Patent application numberDescriptionPublished
20090017035HUMAN ANTIBODIES TO HUMAN DELTA LIKE LIGAND 4 - An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDll4) and blocks hDll4 binding to a Notch receptor. The human anti-hDll4 antibody or antibody fragment binds hDll4 with an affinity of 300 pM or better, as measured by surface plasmon resonance.01-15-2009
20090142354HUMAN ANTIBODIES TO HUMAN DELTA LIKE LIGAND 4 - An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDll4) and blocks hDll4 binding to a Notch receptor. The human anti-hDll4 antibody or antibody fragment binds dimeric hDll4 with an affinity of 75 pM or better, as measured by surface plasmon resonance.06-04-2009
20090246199THERAPEUTIC METHODS FOR INHIBITING TUMOR GROWTH WITH DLL4 ANTAGONISTS - Disclosed is a therapeutic method for inhibiting development or growth of tumors that are resistant to the blockade of delta-like ligand 4 (Dll4), or vascular endothelial growth factor (VEGF), or to other therapeutic agents, by administering the combination of Dll4 antagonist and VEGF antagonist. The combined administration of these two agents, concurrently or sequentially, exhibits synergistic effects on blood vessel development and growth, thereby more effectively inhibiting the tumor growth than an administration of either agent alone. The Dll4 antagonist can be an anti-Dll4 antibody or antibody fragment capable of inhibiting the binding of Dll4 to a Notch receptor, or a fusion protein comprising the extracellular domain of Dll4 or a soluble Notch receptor, or a fragment thereof, fused to a multimerizing component. The VEGF antagonist can be a VEGF trap, anti-VEGF antibody or antibody fragment capable of inhibiting the binding of VEGF to a VEGF receptor.10-01-2009

Irene Okonski-Fernandez, Richmond, CA US

Patent application numberDescriptionPublished
20120024875Insulating cup sleeve - An insulating cup sleeve with a non-woven polyester fabric panel, a thin polyethylene foam panel and a panel retaining loop portion. The fabric panel and the foam panel overlap each other. The fabric panel and the foam panel are wrapped into a circular configuration to form a sleeve. The fabric panel and the foam panel are sewn together by standard sewing means to form the sleeve. The loop portion is sewn in a vertical orientation to the outside of the sleeve. The sleeve is capable of being folded by a user allowing one end of the folded sleeve to be slipped into the loop portion. A preferred embodiment includes the sleeve can be washed by standard means and re-used.02-02-2012

Irene Orienti, Castelplanio (an) IT

Patent application numberDescriptionPublished
20090009287Electric appliance monitoring device - The present invention relates to a monitoring device (01-08-2009

Irene Panero, Stura IT

Patent application numberDescriptionPublished
20110281972POWDER COATING COMPOSITIONS FOR LOW TEMPERATURE CURING AND HIGH FLOW - The present invention relates to powder coating compositions and to components and ingredients for incorporation therein, suitable for low temperature curing schedule and with excellent resistance to outside aging. The powder coating composition can be cured at a temperature from 140° C. to lead to a coating with excellent flow and high gloss.11-17-2011

Irene Pfaffenzeller, Vienna AT

Patent application numberDescriptionPublished
20090263861HOST-VECTOR SYSTEM ANTIBIOTIC-FREE ColE1 PLASMID PROPAGATION - A host-vector system that uses the RNA-based copy number control mechanism of ColE1-type plasmids for regulating the expression of a marker gene allows for antibiotic-free selection of plasmids and is useful for production of plasmid DNA and recombinant proteins.10-22-2009

Irene Plitz, North Plainfield, NJ US

Patent application numberDescriptionPublished
20090004560Electrochemically Self Assembled Batteries - The present invention relates to in situ formation of a single-layered electrochemical cell comprising a full tri-layer battery structure containing a discrete positive electrode, solid state electrolyte, and negative electrode from self-assembled nanocomposites. The single layered cell makes it possible to fabricate cells in three dimensions resulting in a very high energy density power source within very small and/or complex dimensions.01-01-2009

Irene Pyper-Scott, Picton NZ

Patent application numberDescriptionPublished
20090084243Folding electronic instrument - A portable electronic stringed instrument is disclosed. The folding instrument includes a neck portion and a body portion and a connection portion for connecting the neck portion to the body portion. A plurality of adjustable neck strings are disposed between a nut and a neck bridge on the neck portion and a plurality of adjustable body strings are disposed between a nut and a body bridge on the body portion. A finger placement sensor array is disposed on the neck portion proximate the frets and the neck strings. A string vibration sensor is disposed on the body portion proximate the body strings. Although the approximate length of the neck portion can be about 8 to about 12 inches, the fret board on the neck portion includes a plurality of frets that are precisely spaced to provide the fret spacing of a standard, 25.6- to 26-inch “scale length” acoustical guitar.04-02-2009

Irene Reichstein, Halle DE

Patent application numberDescriptionPublished
20090124667Novel Dual-Use Peptidase Inhibitors as Prodrugs for a Therapy of Inflammatory and Other Diseases - Compounds of the general formulae (1) and (2)05-14-2009

Irene Ropiak, Plainsboro, NJ US

Patent application numberDescriptionPublished
20100047175Sincalide Formulations - The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention also features kits and methods for preparing improved sincalide formulations as well as methods for treating, preventing, and diagnosing gall bladder-related disorders using sincalide formulations.02-25-2010

Irene Schober, Zurich CH

Patent application numberDescriptionPublished
20110245379POLYMER COMPRISING AMIDE AND ESTER GROUPS, METHOD FOR PRODUCTION AND USE THEREOF - A polymer (P) is disclosed which includes amide and ester groups. The polymer can be produced by a process whereby, in a first step, a homo- or co-polymer (P1) of (meth)acrylic acid is reacted with a monohydroxy compound (E) at a temperature of up to 200° C., such that, in addition to ester groups, anhydride groups are formed. In a second step, the anhydride groups formed in the first step are reacted with a monoamine compound (A) at temperatures significantly below 100° C. Polymers produced by the above method can be included in hydraulic-setting compositions before and after hardening by an addition of water.10-06-2011
20120012035METHOD FOR PRODUCING CHEMICALLY MODIFIED LIGNIN DECOMPOSITION PRODUCTS - A method for producing chemically modified lignin decomposition products. To this end, a lignin-containing starting material is decomposed into low-molecular and high-molecular lignin decomposition products under acid conditions in the presence of a liquid medium, and the low-molecular lignin decomposition products are at least largely separated in order to obtain a high-molecular fraction. Subsequently, the high-molecular lignin decomposition products present in the high-molecular fraction are converted into chemically modified lignin decomposition products. The chemically modified lignin decomposition products obtained in this way can be used, for example, as dispersing agents, complexing agents, phenol component, flocculant, thickener or auxiliary agents for cementous systems, coatings, paints or adhesives.01-19-2012

Irene Seipelt, Offenbach DE

Patent application numberDescriptionPublished
20090275534NOVEL PYRIDOPYRAZINE DERIVATIVES, PROCESS OF MANUFACTURING AND USES THEREOF - The invention relates to pyrido[2,3-b]pyrazine compounds of general formulae (Ia) and (Ib), to their preparation and use, for example, for the treatment of malignant disorders and other disorders based on pathological cell proliferations.11-05-2009
20100266538QUINOXALINE DERIVATIVES AND THEIR USE FOR TREATING BENIGN AND MALIGNANT TUMOUR DISORDERS - The invention provides quinoxalines of the general formula I which are used as medicaments preferably for treating tumour disorders, in particular in cases of drug resistance to other active compounds and in cases of metastasic carcinoma. The possible applications are not limited to tumour disorders.10-21-2010
20110150831NOVEL NAPHTHYRIDINE DERIVATIVES AND THE USE THEREOF AS KINASE INHIBITORS - The present invention relates to kinase modulators of the naphthyridine type and to the preparation and use thereof as medicaments for the modulation of misdirected cellular signal transduction processes, in particular for influencing the function of tyrosine and serine/threonine kinases and for the treatment of malignant or benign tumours and other disorders based on pathological cell proliferation, such as, for example, restenosis, psoriasis, arteriosclerosis and cirrhosis of the liver.06-23-2011

Patent applications by Irene Seipelt, Offenbach DE

Irene Shackel, South San Francisco, CA US

Patent application numberDescriptionPublished
20080206819Intensified Perfusion Production Method - The invention comprises a process for producing a protein of interest in a perfusion system using induction agents without a substantial loss of cell viability. The invention also comprises methods of growing cells in a perfusion system using induction agents without a substantial loss of cell viability.08-28-2008

Irene Shatova, Jamesburg, NJ US

Patent application numberDescriptionPublished
20080241212Biodegradable, Polymer Coverings for Breast Implants - A biodegradable, flexible covering for a breast implant is provided which comprises one or more biodegradable polymer layers dimensioned and shaped to cover at least a portion of the breast implant. The implant can be inserted into an opening of the covering immediately prior to surgery, but alternate configurations and times of insertion are contemplated as well as open or sheet type devices. The coverings can optionally contain one or more drugs for delivery at the surgical site, particularly for treating or preventing infection, pain, inflammation, capsular contracture, scarring or other complications associated with breast augmentation or breast reconstruction.10-02-2008
20090088548Resorbable Phenolic Polymers - The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.04-02-2009

Irene Spitsberg, Loveland, OH US

Patent application numberDescriptionPublished
20080220172Sintering resistant, low conductivity, high stability thermal barrier coating/environmental barrier coating system for a ceramic-matrix composite (CMC) article to improve high temperature capability - In accordance with an embodiment of the invention, a thermal barrier coating (TBC) for inclusion in a thermal barrier coating/environmental barrier coating system (TBC/EBC system) for use on a silicon containing material substrate is provided. The TBC comprises a compound having a primary constituent portion and a stabilizer portion stabilizing said primary constituent. The primary constituent portion of the TBC comprises hafnia present in an amount of at least about 5 mol % of the primary constituent. The stabilizer portion of said thermal barrier coating comprises at least one metal oxide comprised of cations with a +2 or +3 valence present in the amount of about 10 to about 40 mol % of the thermal barrier coating.09-11-2008
20080292803Low conductivity, thermal barrier coating system for ceramic matrix composite (CMC) articles - In accordance with an embodiment of the invention, a thermal barrier coating for inclusion in a thermal barrier coating/environmental barrier coating system (TBC/EBC system) for use on a silicon based substrate is disclosed. The thermal barrier coating comprising up to about 9 mol percent of a stabilizer and up to 91 mol percent of primary oxide selected from the group consisting of zirconia, hafnia and mixtures thereof. The stabilizer comprises: a first metal oxide selected from the group consisting of yttria, calcia, ceria, scandia, magnesia, india and mixtures thereof, a second metal oxide of a trivalent metal atom selected from the group consisting of lanthana, gadolinia, neodymia, samaria, dysprosia, ytterbia, erbia, and mixtures thereof. The first metal oxide is in an amount of from about 3 to about 5 mol %, the second metal oxide is in an amount of from about 0.25 to about 6 mol %.11-27-2008

Patent applications by Irene Spitsberg, Loveland, OH US

Irene Strueber, Hannover DE

Patent application numberDescriptionPublished
20110194721HEADSET AND HEADPHONE - There is provided a headset having a head band, at least one fork for receiving an earpiece and a receiving portion between an end of the head band and one of the forks. The fork is arranged pivotably about a pivot axis. The fork has a first end having a support element. The receiving portion has a slider having at least two receiving positions. The support element engages into one of the at least two receiving positions of the slider and thus limits the maximum deflection of the fork about the pivot axis.08-11-2011

Irene Troetsch-Schaller, Bissersheim DE

Patent application numberDescriptionPublished
20090307964USE OF SOLUBILIZERS FOR HOMOGENIZING ADDITIVE CONCENTRATES - A cold-stabilized fuel oil composition comprising a major proportion by weight of a middle distillate fuel which boils in the range of 120-500° C. and minor proportions by weight of 12-17-2009
20100048439COLD FLOW IMPROVER - The invention relates to the use of polymers which comprise, in copolymerized form, an α-olefin, at least one alkenyl ester and at least one ester of an α,β-unsaturated carboxylic acid with higher alcohols as an additive for fuel oils and lubricants and especially as a cold flow improver in fuel oils; to the fuel oils and lubricants additized with these polymers; and to additive packages comprising such copolymers. The invention also relates to quaternary and higher copolymers which comprise the abovementioned monomers in copolymerized form.02-25-2010
20100293842PRODUCTION OF ADDITIVE MIXTURES - The invention relates to a method for producing additive mixtures for fuel oils by mixing at least two additive components in a dynamic mixer or a lamination mixer. The invention further relates to additive mixtures obtained by said method and fuel oil compositions containing said additive mixtures.11-25-2010

Irene Trotsch-Schaller, Bissersheim DE

Patent application numberDescriptionPublished
20080274924METHOD FOR PRODUCING MANNICH ADDUCTS THAT CONTAIN POLYISOBUTYLENE PHENOL - Polyisobutenylphenol-containing Mannich adducts are prepared by 11-06-2008
20090188159MIXTURE FROM POLAR OIL-SOLUBLE NITROGEN COMPOUNDS AND ACID AMIDES AS PARAFFIN DISPERSANT FOR FUELS - Mixture of (a) polar oil-soluble nitrogen compounds which are capable of sufficiently dispersing paraffin crystals precipitated out under cold conditions in fuels, (b) oil-soluble acid amides formed from polyamides having from 2 to 1000 carbon atoms and C07-30-2009
20090282732FUEL OIL COMPOSITIONS WITH IMPROVED COLD FLOW PROPERTIES - The use is described of polymers which contain, in copolymerized form, an α-olefin, a vinyl ester and an ester of an α,β-unsaturated carboxylic acid as an additive for fuel oils and lubricants and in particular as a cold flow improver in fuel oils. In addition, the fuel oils and lubricants additized with these polymers; and also additive packages comprising such polymers are described.11-19-2009

Patent applications by Irene Trotsch-Schaller, Bissersheim DE

Irene Trötsch-Schaller, Bissersheim DE

Patent application numberDescriptionPublished
20090188159MIXTURE FROM POLAR OIL-SOLUBLE NITROGEN COMPOUNDS AND ACID AMIDES AS PARAFFIN DISPERSANT FOR FUELS - Mixture of (a) polar oil-soluble nitrogen compounds which are capable of sufficiently dispersing paraffin crystals precipitated out under cold conditions in fuels, (b) oil-soluble acid amides formed from polyamides having from 2 to 1000 carbon atoms and C07-30-2009
20110118159FUEL OIL COMPOSITIONS WITH IMPROVED COLD FLOW PROPERTIES - The use is described of polymers which contain, in copolymerized form, an α-olefin, a vinyl ester and an ester of an α,β-unsaturated carboxylic acid as an additive for fuel oils and lubricants and in particular as a cold flow improver in fuel oils. In addition, the fuel oils and lubricants additized with these polymers; and also additive packages comprising such polymers are described.05-19-2011
20110251114METHOD FOR PRODUCING MANNICH ADDUCTS THAT CONTAIN POLYISOBUTYLENE PHENOL - Polyisobutenylphenol-containing Mannich adducts are prepared by 10-13-2011
20110271586TERPOLYMER AND USE THEREOF FOR IMPROVING THE COLD FLOW PROPERTIES OF MIDDLE DISTILLATE FUELS - A terpolymer formed from (A) ethylene, (B) (i) C11-10-2011
20120005951COPOLYMER WITH HIGH CHEMICAL HOMOGENEITY AND USE THEREOF FOR IMPROVING THE COLD FLOW PROPERTIES OF FUEL OILS - A copolymer with high chemical homogeneity, consisting of (A) 50 to 30% by weight of ethylene, (B) 50 to 70% by weight of C01-12-2012

Patent applications by Irene Trötsch-Schaller, Bissersheim DE

Irene Tseti, Kifissia GR

Patent application numberDescriptionPublished
20100152296PHOTOPOLYMERIZATION MATERIAL FOR GUMS ISOLATION - The main goal of the present invention is the development of a polymerizable material for isolation and protection of the gums and generally the soft tissues of the oral cavity. For better protection during various procedures of the dental surfaces. The composition of the material can contain many other substances that strengthen its qualities and protective action. Such substances can be various substances that have antioxidative, sedative, anti-inflammatory, analgesic, anti-irritant action etc.06-17-2010

Irene Vanderwerff, Manhattan, KS US

Patent application numberDescriptionPublished
20080299090Use Of Umbilical Cord Matrix Cells - The invention relates to the isolation and use of stem cells from amniote species (potentially any animal with an umbilical cord, including humans). More particularly the invention relates to obtaining stem cells that are at least multipotent and may be totipotent or nearly totipotent and are envisaged to have a variety of end uses. The cells of the present invention are immunosuppressive and may be used to inhibit the immune response in a subject.12-04-2008

Irene Vaulont, Buchs CH

Patent application numberDescriptionPublished
20090253936Process for Producing (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-d- iol - A process for producing (1R,3R,6R)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or (1S,3S,6S)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or mixtures thereof.10-08-2009
20100173994Synthesis of triethylenetetramines - Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.07-08-2010
20120029203Synthesis Of Triethylenetetramines - Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.02-02-2012

Patent applications by Irene Vaulont, Buchs CH

Irene Wagner-Dobler, Evessen DE

Patent application numberDescriptionPublished
20110034708PHARMACEUTICAL COMPOSITION EFFECTIVE AGAINST BIOFILMS - The invention provides a compound termed Carolacton having the structure and derivatives thereof for medical use against biofilm formation by bacteria.02-10-2011

Irene Waizenegger, Ingelheim Am Rhein DE

Patent application numberDescriptionPublished
20100311721COMPOUNDS - The present invention encompasses compounds of general formula (1)12-09-2010

Irene Waizenegger, Vienna AT

Patent application numberDescriptionPublished
200902036734-HETEROCYCLOALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS - The present invention encompasses compounds of general Formula (I) wherein X and R08-13-2009
20100113414THIAZOLYL-DIHYDRO-INDAZOLES - The present invention encompasses compounds of the general formula (1)05-06-2010
20100240657CHEMICAL COMPOUNDS - The present invention encompasses compounds of general formula (1) wherein the groups R09-23-2010
20110183952NEW CHEMICAL COMPOUNDS - The present invention encompasses compounds of general formula (1), wherein the groups R07-28-2011

Patent applications by Irene Waizenegger, Vienna AT

Irene Zeinden, Le Mont Sur Lausanne CH

Patent application numberDescriptionPublished
20100255114METABOLIC IMPRINTING - The present invention generally relates to the field of nutrition. In particular the present invention relates to infant nutrition in the post natal period and in early life, more particular during the age period of 6-36 months or during a part thereof One embodiment of the present invention is a kit of diet compositions for children during the age period of 6-36 months or during a part thereof, wherein the macronutrient content of the compositions is gradually changing in the form of a straight line from a composition that comprises about 40-50% energy from fat and about 40-49% energy from carbohydrates for children at the age of 6 months to a composition that comprises about 30-35% energy from fat and about 50-55% energy from carbohydrates for children at the age of 36 months, and its use to prevent obesity later in life. Another embodiment relates to a range of shclf-stablc baby food products having an optimal energy profile for meeting the nutritional needs of an infant at a specific stage of infant development.10-07-2010

Irène Corthesy-Theulaz, Epalinges CH

Patent application numberDescriptionPublished
20080274127AMINO ACID SUPPLEMENTATION FOR A HEALTHY MICROBIOTA ECOSYSTEM - The present invention pertains to a nutritional composition for reconstituting an optimal healthy microbiota ecosystem in humans or animals. In particular, the present invention relates to an ingestible carrier containing specific amino acids designed to favor the growth of bacteria favorable to individuals health or for reducing the risk of developing deleterious events. The invention also pertains to the use of specific amino acids for reconstituting an optimal healthy microbiota ecosystem in humans or animals, in particular in infants, critically ill patients, in the case of chronic diseases or any stresses impacting the gut and in elderly people.11-06-2008
20090142375LIPOTEICHOIC ACID FROM LACTIC ACID BACTERIA AND ITS USE TO MODULATE IMMUNE RESPONSES MADIATED BY GRAM-NEGATIVE BACTERIA, POTENTIAL PATHOGENIC GRAM-POSITIVE BACTERIA - The invention relates to a composition for modulating the immune responses induced by Gram negative bacteria, potential pathogenic Gram positive bacteria and/or their derivatives, comprising lipoteichoic acid from lactic acid bacteria as an active ingredient. It also relates to the use of a lipoteichoic acid from lactic acid bacteria as an active ingredient and/or lactic acid bacteria producing it and/or its supernatant of culture, in the manufacture of a medicament, an oral or topical product for cosmetic, dermatological or ophtalmological applications, a food or petfood composition for modulating bacterial colonisation, immune responses and decreasing the inflammatory processes associated with bacterially-mediated disease and infection in the gastrointestinal tract, bone, skin, eye, ear, lung and oral cavity. The invention also relates to lipoteichoic acid selected thereof.06-04-2009
20100028316MODERATING THE EFFECT OF ENDOTOXINS - The present invention relates to the use of an oral composition comprising yeast extract, in the manufacture of an oral composition to treat the effects of infection by pathogenic bacteria such as 02-04-2010

Patent applications by Irène Corthesy-Theulaz, Epalinges CH

Irène Elguidj, Neuilly FR

Patent application numberDescriptionPublished
20100150853Artificially coloring the skin with a carotene compound, a xanthophyll compound and a lipophilic green dye composition - A method for artificially coloring the skin entails topical application thereon of a composition containing, formulated into a physiologically acceptable medium: 06-17-2010

Irène Tatischeff, Orsay FR

Patent application numberDescriptionPublished
20100178702EXTRACELLULAR VESICLES FROM NON-PATHOGENIC AMOEBAE USEFUL AS VEHICLE FOR TRANSFERRING A MOLECULE OF INTEREST TO AN EUKARYOTIC CELL - The invention relates to membrane vesicles from non-pathogenic amoeba, in particular from the amoeba 07-15-2010