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Imamura, Ibaraki

Hideaki Imamura, Ibaraki JP

Patent application numberDescriptionPublished
20090131464SPIROCHROMANONE DERIVATIVES AS ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS - The invention relates to a compound of a formula (I): or a pharmaceutically acceptable salt or ester thereof, useful as a therapeutic agent for various ACC-related disorders.05-21-2009

Morikazu Imamura, Ibaraki JP

Patent application numberDescriptionPublished
20110124843METHOD FOR EFFICIENTLY AMPLIFYING ABNORMAL PRION PROTEIN DERIVED FROM BSE - A method for efficiently amplifying abnormal prion protein (PrP05-26-2011

Ryuuichi Imamura, Ibaraki JP

Patent application numberDescriptionPublished
20080202303DESK-TOP CUTTING MACHINE - The invention provides a desk-top cutting machine including a turntable on a upper surface of which a wood material can be placed, a fence part which is provided on the turntable and has a side surface for positioning the wood material, and a cutting part having a swinging shaft part which is disposed on the turntable, supports a cutting blade up of the turntable, and swings the cutting blade approachably to and separably from the turntable. Herein, on the upper surface and the side surface, recess portions are formed, and plate materials which cover the recess portions are provided.08-28-2008
20090260498Bench Cutter - According to an aspect of the invention, a bench cutter like a miter saw including: a drive portion driving a cutting blade; a base portion supporting a workpiece; a cutting portion arranged on the base portion, pivotally supporting the cutting blade above the base portion, and configured to make the cutting blade come close to and separate from the base portion; and a supporting portion connected to the base portion and movably supporting the cutting portion, wherein the cutting portion including: a transmission portion for transmitting power of the drive portion to the cutting blade; and a gear case covering the transmission mechanism and having a lower face portion opposed to an upper face of the base portion, wherein the transmission portion including: a spindle concentrically supporting the cutting blade; and a cutting blade fixing portion having a flange for fixing the cutting blade to the spindle.10-22-2009
20100095823BENCH CUTTER - In a bench cutter in which a turn table 04-22-2010

Patent applications by Ryuuichi Imamura, Ibaraki JP

Shinichi Imamura, Ibaraki JP

Patent application numberDescriptionPublished
20090306374FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF - The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof.12-10-2009
20100168424FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF - The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof07-01-2010
20100273788FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF - The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof.10-28-2010

Toru Imamura, Ibaraki JP

Patent application numberDescriptionPublished
20090286965MUTANT GROWTH FACTORS WITH ALTERED RECEPTOR SPECIFICITIES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME - Disclosed is a mutant protein having an altered fibroblast growth factor receptor specificity, which is produced by deleting one or more amino acid residues from the N-terminus of the amino acid sequence of naturally secreted fibroblast growth factor 18. The protein mutant can be used in a pharmaceutical composition for regulating hair regeneration or growth or a pharmaceutical composition for regulating bone or cartilage formation.11-19-2009
20100183733HAIR GROWTH-INHIBITING AGENT - A hair removing agent or a hair growth inhibiting agent is provided by determining an endogenous factor having a hair growth inhibitory activity, screening for substances having an activity similar to that of the endogenous factor or substances enhancing the activity or expression of the endogenous factor, and utilizing the physiological activities of such substances. It has been found that FGF18 inhibits hair growth. A method of screening for FGF18-like active substances, substances that promote the activity of FGF18 or substances that promote the expression of FGF18 to thereby obtain candidates for the hair growth inhibiting agent or hair removing agent is disclosed. Also disclosed is a hair growth inhibiting agent or a hair removing agent comprising, as an active ingredient, FGF18 and/or an FGF18 partial peptide, or an FGF18-like active substance and/or a substance that promotes the activity or expression of FGF18 (e.g., Digenea simplex extract).07-22-2010
20100184665METHOD FOR ACTIVATING RECEPTOR BY COFACTOR AND METHOD FOR UTILIZING LIGAND ACTIVITY - Using betaKlotho or a substance that increases or inhibits betaKlotho activity as an agent for controlling the activity of FGF21 mediated by an FGF receptor, the present invention provides a pharmaceutical composition comprising such betaKlotho or such substance as an active ingredient, particularly, a pharmaceutical composition for anti-metabolic syndrome, and further particularly, a pharmaceutical composition for therapeutic or preventive use associated with the control of blood glucose level. In addition, the present invention provides a screening system for each of a substance that enhances or suppresses betaKlotho activity, an FGF21-like active substance, and a betaKlotho-like active substance, which uses a cell system that has expressed an FGF receptor and/or betaKlotho on the surface thereof.07-22-2010
20100203055HAIR REGROWTH PROMOTER - It is intended to provide a hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia by determining an endogenous factor that inhibits hair growth and screening for substances that inhibit the activity or expression of the endogenous factor. It has been found that FGF18 inhibits hair growth. A method of screening for substances that inhibit the activity of FGF18 or substances that inhibit the expression of FGF18 to thereby obtain candidates for the hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia is disclosed. Also disclosed is a hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia comprising, as an active ingredient(s), a substance that inhibit the activity of FGF18 and/or a substance that inhibits the expression of FGF18 such as a partial peptide of FGF18 or a 08-12-2010
20100286042Medicinal Composition Containing Highly Functionalized Chimeric Protein - There is provided an FGF2 substitute containing medicinal composition which comprises, as an active ingredient, a chimeric protein comprising the amino acid sequence of an FGF1 protein in which a partial sequence including a sequence of at least positions 62-83 within a sequence of positions 41-83 is substituted with a partial sequence at the corresponding positions in the amino acid sequence of an FGF2 protein; and the remaining region is formed of the amino acid sequence of FGF1. In particular, this medicinal composition is used for wound healing and for the prevention and treatment of radiation-induced damage, and it exhibits a pharmacological action superior to that of an FGF2 medicinal composition, and further, it can be easily formulated into a preparation.11-11-2010

Patent applications by Toru Imamura, Ibaraki JP