| Patent application number | Description | Published |
| 20080269561 | ENDOSCOPIC IMAGING SYSTEM - An endoscopic imaging system includes a reusable control cabinet having a number of actuators that control the orientation of a lightweight endoscope that is connectable thereto. The endoscope is used with a single patient and is then disposed. The endoscope includes an illumination mechanism, an image sensor and an elongate shaft having one or more lumens located therein. A polymeric articulation joint at the distal end of the endoscope allows the distal end to be oriented by the control cabinet. The endoscope is coated with a hydrophilic coating that reduces its coefficient of friction and because it is lightweight, requires less force to advance it to a desired location within a patient. | 10-30-2008 |
| 20080281273 | Microneedle transdermal transport device - A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir. | 11-13-2008 |
| 20080319392 | MICRONEEDLE TRANSPORT DEVICE - A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body. | 12-25-2008 |
| 20100004624 | MEASURING PROPERTIES OF AN ANATOMICAL BODY - A medical device includes a sensor that is configured to measure a property of an outer layer of an anatomical body surface. The sensor includes a source probe configured stimulate a local surface of the outer layer of an anatomical body surface. The sensor also includes a detector configured to measure a response of the outer layer resulting from the source probe stimulation. A controller coupled to the source probe and the sensor drives the source probe using a tailored stochastic sequence and determines the property of the outer layer using the measured response received from the detector. The sensor can be used with medical devices, such as drug delivery devices including microneedle transport devices and needleless injection devices. | 01-07-2010 |
| 20100016827 | NEEDLE-FREE INJECTOR DEVICE WITH AUTOLOADING CAPABILITY - A needle-free transdermal transport device includes a chamber ( | 01-21-2010 |
| 20110028676 | Molecular Actuators, and Methods of Use Thereof - The synthesis of thiophene based conducting polymer molecular actuators, exhibiting electrically triggered molecular conformational transitions is reported. Actuation is believed to be the result of conformational rearrangement of the polymer backbone at the molecular level, not simply ion intercalation in the bulk polymer chain upon electrochemical activation. Molecular actuation results from π-π stacking of thiophene oligomers upon oxidation, producing a reversible molecular displacement that leads to surprising material properties, such as electrically controllable porosity and large strains. The existence of active molecular conformational changes is supported by in situ electrochemical data. Single molecule techniques have been used to characterize the molecular actuators. | 02-03-2011 |
| 20110054354 | Nonlinear System Identification Techniques and Devices for Discovering Dynamic and Static Tissue Properties - A device for measuring a mechanical property of a tissue includes a probe configured to perturb the tissue with movement relative to a surface of the tissue, an actuator coupled to the probe to move the probe, a detector configured to measure a response of the tissue to the perturbation, and a controller coupled to the actuator and the detector. The controller drives the actuator using a stochastic sequence and determines the mechanical property of the tissue using the measured response received from the detector. The probe can be coupled to the tissue surface. The device can include a reference surface configured to contact the tissue surface. The probe may include a set of interchangeable heads, the set including a head for lateral movement of the probe and a head for perpendicular movement of the probe. The perturbation can include extension of the tissue with the probe or sliding the probe across the tissue surface and may also include indentation of the tissue with the probe. In some embodiments, the actuator includes a Lorentz force linear actuator. The mechanical property may be determined using non-linear stochastic system identification. The mechanical property may be indicative of, for example, tissue compliance and tissue elasticity. The device can further include a handle for manual application of the probe to the surface of the tissue and may include an accelerometer detecting an orientation of the probe. The device can be used to test skin tissue of an animal, plant tissue, such as fruit and vegetables, or any other biological tissue. | 03-03-2011 |
| 20110054355 | Identification Techniques and Device for Testing the Efficacy of Beauty Care Products and Cosmetics - A method for testing the effect of a skin care product includes measuring a mechanical property of skin tissue using nonlinear stochastic system identification, applying the product to the skin, repeating the measurement of the mechanical property after the application of the product, and comparing the before and after measurements to quantify the effect of the product. | 03-03-2011 |
| 20110065590 | Method and Apparatus for Performing Microassays - A method and apparatus for analyzing a plurality of substances. A platen is provided having two substantially parallel planar surfaces and a plurality of through-holes. An optical arrangement analyzes light emanating from the through-holes. The through-holes may be individually addressable, and may have volumes less than 100 nanoliters. Samples may be accurately dispensed, diluted and mixed in accordance with embodiments of the invention, and may be plated onto walls of the through-holes, and then subsequently resuspended prior to characterization, or, alternatively, retained in the through-holes by surface tension. | 03-17-2011 |
| 20110082388 | BI-DIRECTIONAL MOTION OF A LORENTZ-FORCE ACTUATED NEEDLE-FREE INJECTOR (NFI) - The present invention relate to a method and corresponding apparatus for extraction of a sample from a sample source. A fluid is injected into the sample source and the sample source is vibrated. A sample is withdrawn from the vibrated sample source and the sample source is evaluated by measuring one or more identifying parameters in the withdrawn sample. | 04-07-2011 |
| 20110108339 | Electric motor - A rotary and linear motion device includes a magnetic stator assembly, opposed electromagnetic actuators, and a linear-to-rotary converter (e.g., cam). Each electromagnetic actuator includes a coil that is configured to reciprocate relative to the magnetic stator assembly or to linearly translate in a common direction relative to the magnetic stator assembly. The electromagnetic actuators are coupled to the linear-to-rotary converter and upon reciprocation or linear translation, drive the linear-to-rotary converter in rotary or linear motion. The device may be located inside a wheel, which may be part of a vehicle. If part of a wheel of a vehicle, the device can be used to provide propulsion, steering, braking, and suspension for the vehicle. | 05-12-2011 |
| 20110109051 | Tunable pneumatic suspension - A tunable pneumatic suspension includes a piston and two opposed pneumatic chambers. The two champers apply opposed pneumatic pressures to opposite faces of the piston. The tunable pneumatic suspension also includes a pneumatic controller that independently controls the pressure in each of the chambers. The independent control of the two chambers allows the suspension to change the relative positions of the piston and the chambers by differing the pressures in each chamber, and allows the suspension to change its stiffness by increasing or decreasing the pressures in each of the chambers by equal amounts. If used in a vehicle, changing the relative positions of the piston and the chambers can change the ride height of the vehicle, and changing the stiffness of the suspension can change the stiffness of the vehicle's ride. | 05-12-2011 |
| 20110109174 | Electric generator - An electric generator device includes a magnetic stator assembly, opposed coils, and a rotary-to-linear converter (e.g., cam). The coils are configured to reciprocate relative to the magnetic stator assembly or to linearly translate in a common direction relative to the magnetic stator assembly. The coils are coupled to the cam and, upon rotary or linear motion of the cam, reciprocate or linearly translate relative to the magnetic stator assembly. The reciprocation or linear translation of the coils creates an electric current flowing through the coils, which may then be harvested. | 05-12-2011 |
| 20110109413 | Electric coil and method of manufacture - Instead of being made from one continuous piece of material, a coil includes multiple flat coil segments that are stacked together and electrically coupled in series. In many embodiments, the coil segments are U-shaped segments, and the segments are arranged so that each segment is rotated (e.g., by 270 degrees) with respect the segment it follows. The stacked coils may then be fastened together using, for example, bolts through the corners of the coil segments. The combined coil segments form a continuous coil. | 05-12-2011 |
| 20110143310 | Lorentz-Force Actuated Cleaning Device - A method of surface treatment includes sensing a surface condition and controlling ejection of a fluid jet against the surface to treat the surface based on the sensed condition. The fluid may be a liquid and may be carried in a self-contained reservoir in a handle of a fluid ejection device. The liquid can be a cleansing solution and may contain cleaning particles. The ejection can be controlled to clean a part of the surface at high pressure and to reduce pressure applied to another part of the surface, for example, to clean the surface. The method may further include automatically scanning the fluid jet relative to a handle of an injection device. In an embodiment, the fluid is ejected by means of a fluid ejector comprising a stationary magnet assembly providing a magnetic field and a coil assembly, slidably disposed with respect to the magnet assembly, the coil assembly driving ejection of the fluid jet. Sensing the surface condition can include measuring a response of the surface to a mechanical perturbation and may include sensing an acoustic signal reflected from the surface. The mechanical perturbation can include applied force and the measured response can include deformation of the surface. The method may further include mechanically disturbing the surface with the fluid jet. A surface treatment device includes a fluid ejector that ejects fluid against a surface and a servo controller controlling pressure of ejected fluid in response to a sensed surface condition. The fluid jet can have a diameter of less than 500 microns, a peak relative pressure of at least 1 kilopascal and velocity of at least 1 meter per second. | 06-16-2011 |
| 20110166549 | BI-DIRECTIONAL MOTION OF A LORENTZ-FORCE ACTUATED NEEDLE-FREE INJECTOR (NFI) - The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber. A bi-directional electromagnetic actuator is in communication with the chamber. The actuator, when activated, generates a pressure within the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body. | 07-07-2011 |