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Ian Henderson

Ian Henderson, Hopewell, NJ US

Patent application numberDescriptionPublished
20080249100PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS - The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I:10-09-2008
20080312215Substituted [1,4]-diazepanes as CXCR3 antagonists and their use in the treatment of inflammatory disorders - CXCR3 inhibitors of formula12-18-2008
20090005568Substituted 2-aminothiazoles for treating neurodegenerative diseases - The invention relates to substituted 2-aminothiazole derivatives useful in treating disorders that are mediated by A01-01-2009
20090023723Purinone derivatives for treating neurodegenerative diseases - The invention relates to purinone derivatives useful in treating disorders that are mediated by adenosine receptor function, including neurodegenerative diseases and inflammation. The compounds are of the general formula:01-22-2009
20090312320METHODS OF TREATMENT COMPRISING THE ADMINISTRATION OF HALOARYL SUBSTITUTED AMINOPURINES OR COMPOSITIONS THEREOF - Provided herein are Aminopurine Compounds having the following structure:12-17-2009
20100113463PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS - The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I:05-06-2010
201100711302-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES - The invention relates to 2-aminobenzimidazoles useful in treating disorders that are mediated by A03-24-2011

Patent applications by Ian Henderson, Hopewell, NJ US

Ian Henderson, Middlesbrough GB

Patent application numberDescriptionPublished
20080267843Spinning Disc Reactor with Spiral Passageway for Heat Transfer Fluid - There is disclosed a reactor apparatus including a support element that is rotatable about an axis and which has a first surface generally centered on the axis. The first surface is adapted for outward radial flow of a thin film of fluid phase reactant thereacross when supplied thereto as the support element is rotated. The support element also has a second surface opposed to the first surface and which is in thermal communication with the first surface. The second surface is provided with a spiral passageway generally centered on the axis and also with means for supplying a heat transfer fluid to the spiral passageway. By providing a spiral passageway for the heat transfer fluid, improved heat transfer from the first surface to the heat transfer fluid is obtained.10-30-2008

Patent applications by Ian Henderson, Middlesbrough GB

Ian Henderson, Frederick, MD US

Patent application numberDescriptionPublished
20080213310Use of lytic toxins and toxin conjugates - Agents are provided which are capable of inhibiting the cell division cycle in a target cell of interest. The agents comprise first and second components, wherein the first component is a targeting moiety which is capable of directing the second component to the target cell of interest. The second component is capable of inhibiting the cell division cycle in the target cell of interest. The agents are preferably provided in the form of conjugates, and the second component is preferably a cytolethal distending toxin. Methods for the preparation of the agents, and the use thereof for treating proliferative cell disorders and intracellular pathogens are also provided.09-04-2008