Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Ian Churcher
Ian Churcher, Herts GB
| Patent application number | Description | Published |
|---|---|---|
| 20090192155 | Identification of Compounds Suitable for Treating Ad - The invention provides a method of screening for compounds which inhibit the hyperphosphorylation of tau, and hence are suitable for treating AD and related conditions. | 07-30-2009 |
| 20090247504 | Indazole Derivatives for Treatment of Alzheimer's Disease - Compounds of formula (IA) and (IB) are inhibitors of MARK, and hence are suitable for treatment of Alzheimer's disease. | 10-01-2009 |
| 20100234463 | Method for Identifying Modulators of Gamma Secretase or Notch - The present invention relates to methods for high throughput screening to identify selective modulators of γ-secretase. Such modulators selectively block γ-secretase activity without affecting Notch cleavage and signaling. Said methods employ the use of high content screening methodologies to measure and quantify the translocation of the Notch intracellular domain (NICD) between the nucleus and cytoplasm in cells and the activation of Notch. | 09-16-2010 |
| 20100240647 | Treatment of Alzheimer's Disease and Related Conditions - Compounds of formula (I) inhibit microtubule affinity regulating kinase (MARK), and hence are suitable for treating diseases associated with abnormal phosphorylation of tau. | 09-23-2010 |
Ian Churcher, Royston GB
| Patent application number | Description | Published |
|---|---|---|
| 20080300261 | Arylacetic Acids and Related Compounds for Treatment of Alzheimer's Disease - Compounds of formula I | 12-04-2008 |
| 20100048555 | IMIDAZOTHIAZOLE DERIVATIVES AS MARK INHIBITORS - Compounds of formula (I): are inhibitors of MARK, and hence useful for treatment of disorders involving 10 hyperphosphorylation of tau. | 02-25-2010 |
Ian Churcher, Hertfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100009987 | AMINOTHIAZOLE DERIVATIVES AS INHIBITORS OF MARK - Compounds of formula (I): inhibit microtubule affinity regulating kinase (MARK) and therefore find use in treatment of neurodegenerative diseases associated with hyperphosphorylation of tau. | 01-14-2010 |
Ian Churcher, Great Dunmow GB
| Patent application number | Description | Published |
|---|---|---|
| 20090131419 | Sulphones which modulate the action of gamma secretase - Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease. | 05-21-2009 |