Huizinga, NL
Alex Huizinga, Almelo NL
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20130014595 | FORCE SENSOR ASSEMBLY AND METHOD FOR ASSEMBLING A FORCE SENSOR ASSEMBLYAANM Huizinga; AlexAACI AlmeloAACO NLAAGP Huizinga; Alex Almelo NLAANM Zwijze; RobertAACI VriezenveenAACO NLAAGP Zwijze; Robert Vriezenveen NLAANM Pijpers; MartijnAACI EnschedeAACO NLAAGP Pijpers; Martijn Enschede NLAANM Berkel; BennieAACI WierdenAACO NLAAGP Berkel; Bennie Wierden NL - The force sensor assembly has axis of measurement along an axial direction of the force sensor assembly and comprises a force ring provided with at least two sensing elements, a printed circuit board having electronic components thereon, a covering plate for holding the printed circuit board onto the force ring, and a sensor cap covering the printed circuit board and covering plate and attached to the force ring. Manufacturing is easily accomplished using stacking, fixing and welding. | 01-17-2013 |
Herman Huizinga, Drachten NL
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20080216668 | Detector for Electric Cooking Appliance Detecting Presence of a Bowl and Its Temperature - An electric cooking appliance comprising heating means ( | 09-11-2008 |
Hindrik Huizinga, 3133 At Vlaardingen NL
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20130171310 | EDIBLE FAT CONTINUOUS SPREADS - The invention relates to a method of preparing an edible fat continuous spread comprising a dispersed aqueous phase and crystalline non-esterified plant sterol, said method comprising the steps of preparing a fat continuous emulsion and mixing said emulsion with fast re-crystallized non-esterified plant sterol. | 07-04-2013 |
Hindrik Huizinga, At Vlaardingen NL
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20110311707 | PROCESS FOR THE PREPARATION OF AN EDIBLE FAT CONTINUOUS FOOD PRODUCT - The invention relates to Process suitable for implementation at factory scale for manufacturing an edible fat continuous food product comprising the steps of a. providing a fat mixture comprising fat powder and liquid oil; b. providing an aqueous phase; c. forming the edible fat continuous food product by mixing the aqueous phase and the fat mixture; d. packing of the food product; wherein the fat powder comprises structuring fat; the amount of fat powder in the fat mixture based on total amount of fat mixture is 8 to 25 wt % the fat mixture prior to mixing is kept at a temperature of 0 to 12 degrees Celsius; the fat mixture is kept in motion prior to mixing; and the temperature of the aqueous phase at the time of mixing the aqueous phase and the fat mixture is such that the temperature of the mixture of the aqueous phase and the fat mixture is equal to or below 25 degrees Celsius. | 12-22-2011 |
Jozef Huizinga, Wedde NL
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20100192318 | MULTI-SIDED WASHCLOTH - A washcloth ( | 08-05-2010 |
20110056019 | HOIST PROVIDED WITH A CLAMPING DEVICE FOR MOVING PERSONS - A hoist for moving persons, provided with a base structure, provided with one lifting column having a straight longitudinal axis and a lower end and which is provided with a first actuator for realizing a lifting movement, provided with a clamping device which is connected to the lifting column so as to be movable in the direction of the longitudinal axis and has at least one set of cooperating clamping elements which are designed for clamping a person to be moved, provided with a horizontal shaft by which the lifting column is pivotally connected to the base structure, and provided with a second actuator connected to the lifting column and to the base structure, and configured for varying the pivotal position of the lifting column with respect to the base structure. | 03-10-2011 |
20110061952 | MOBILE FRAME FOR MOVING LESS ABLE-BODIED PERSONS - A mobile frame, for instance for moving less able-bodied persons, comprising a castor with a wheel drive and pivot drive and operating means for operating the wheel drive and the pivot drive for moving the frame, wherein the operating means comprise a handle connected to the bearing structure, a force detection assembly provided on the handles and/or on the bearing frame, and which is configured for producing signals which contain information about both the size of force and the direction of force exerted on the handle, a control which is configured for energizing the pivot drive for controlling the rotational position of drive wheel support about the pivot depending on the direction of force, and wherein the control is configured for energizing the wheel drive depending on the size of force exerted on the handle. | 03-17-2011 |
Thomas Huizinga, Leiden NL
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20090117584 | Non-Human mammalian Arthritis Model Featuring Human Antibodies Against Citrul-Linated Proteins - Use of a non-human mammalian disease model, wherein the non-human mammal has been implanted with human synovial tissue or other human inflamed tissue containing anti-CCP (cyclic citrullinated peptide) antibody producing cells for (i) analyzing cellular processes in a disease associated with anti-CCP antibodies in such human synovial tissue or other human inflamed tissue, (ii) studying the role of anti-CCP antibodies in the induction and progression of a disease associated with anti-CCP antibodies, (iii) testing the efficacy of a therapeutic agent for the prevention or treatment of a disease associated with anti-CCP antibodies, and (iv) identifying a therapeutic agent useful for the prevention or treatment of a disease associated with anti-CCP antibodies. In one embodiment the non-human mammalian disease model is a mouse, such as a SCID mouse, and the disease associated with anti-CCP antibodies is arthritis, such as RA (rheumatoid arthritis). | 05-07-2009 |
Thomas Willem Johannes Huizinga, Leiden NL
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20140162297 | ANTI-CARBAMYLATED PROTEIN ANTIBODIES AND THE RISK FOR ARTHRITIS - Antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. Described are means and methods for determining antibodies against homocitrulline-containing proteins or carbamylated proteins/peptides (anti-CarP) for the classification of individuals suffering from, or at risk of suffering from, arthritis. | 06-12-2014 |
Tom J.w. Huizinga, Leiden NL
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20100240737 | ENZYME-PRODRUG THERAPY FOR PROSTHETIC JOINT REPAIR - The invention relates to the use of gene therapy in the treatment of aseptic loosening of orthopaedic prostheses and discloses methods of refixing such prostheses without open revision surgery. In particular, it provides adenoviral vectors and prodrugs for simultaneous, separate or sequential use in the destruction of interface tissue allowing subsequent recementing of loose prostheses in a minimally invasive manner. | 09-23-2010 |
Tom Willem Johannes Huizinga, Leiden NL
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20090029379 | GENETIC MARKERS FOR PROGNOSIS OF ANTIFOLATE TREATMENT EFFICACY - Methods and kits for predicting the efficacy of antifolate (e.g., methotrexate) treatment of rheumatoid arthritis by detecting polymorphisms, particularly single nucleotide polymorphisms, in adenosine pathway genes. | 01-29-2009 |
20100240541 | GENETIC MARKERS FOR PROGNOSIS OF ANTIFOLATE TREATMENT EFFICACY - Methods and kits for predicting the efficacy of antifolate (e.g., methotrexate) treatment of rheumatoid arthritis by detecting polymorphisms, particularly single nucleotide polymorphisms, in adenosine pathway genes. | 09-23-2010 |
Tom Willen Johannes Huizinga, Nd Leiden NL
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20080288177 | PHARACOGENETIC METHOD FOR PREDICTION OF THE EFFICACY OF METHOTREXATE MONOTHERAPY IN RECENT-ONSET ARTHRITIS - Pharmacogenetic methods for determining a predicting responsiveness to antifolate therapy for subjects that present with recent-onset undifferentiated arthritis. The methods are based on the determination of a set of clinical parameter values and determining a predicted responsiveness to antifolate therapy by correlating the parameter values with predefined responsiveness values associated with ranges of parameter values. Parameters values that are decisive for responsiveness to antifolate therapy may include polymorphisms in the methylenetetrahydrofolate dehydrogenase (MTHFD1) gene as well as in three genes involved in the adenosine release pathway, the presence or absence of Rheumatoid factors, gender, pre- or postmenopausal status and/or smoking status. | 11-20-2008 |
20130196313 | Pharmacogenetic Method for Prediction of the Efficacy of Methotrexate Monotherapy in Recent-Onset Arthritis - Pharmacogenetic methods for determining a predicting responsiveness to antifolate therapy for subjects that present with recent-onset undifferentiated arthritis. The methods are based on the determination of a set of clinical parameter values and determining a predicted responsiveness to antifolate therapy by correlating the parameter values with predefined responsiveness values associated with ranges of parameter values. Parameters values that are decisive for responsiveness to antifolate therapy may include polymorphisms in the methylenetetrahydrofolate dehydrogenase (MTHFD1) gene as well as in three genes involved in the adenosine release pathway, the presence or absence of Rheumatoid factors, gender, pre- or postmenopausal status and/or smoking status. | 08-01-2013 |