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Huguet
Helene Huguet, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20080199528 | Colonic delivery of metallo-dependent enzymes - Drug delivery systems for delivering agents capable of reducing the quantity of residual antibiotics reaching the colon following oral or parenteral antibiotic therapy, and for delivering metallo-dependent enzymes, and methods of using the drug delivery systems, are disclosed. The drug delivery systems include pectin beads that encapsulate the active agent (which can be a metallo-dependent enzyme), where the pectin is crosslinked with zinc or any divalent cation of interest and the pectin beads are coated with Eudragit®-type polymers. The drug delivery systems are orally administrable, but can deliver the active agents to the colon. In some embodiments, they can administer the agents to various positions in the gastro-intestinal tract, including the colon. One metallo-dependent enzyme is the β-lactamase L1 from | 08-21-2008 |
Helene-Celine Huguet, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20090324568 | Colonic Delivery of Adsorbents - Orally administrable, site-specific (colonic), particulate delivery systems including adsorbents are disclosed. When delivered specifically to the colon, they can remove various substances present in, or as they reach, the colon. Methods of treatment using the delivery systems, and methods of preparing the delivery systems, are also disclosed. The particulate delivery systems are based on adsorbent matrices encapsulated into and/or onto particles, which selectively deliver the adsorbents to the colon. Representative drug delivery devices include pectin beads, which can optionally be crosslinked with metal ions such as zinc and/or calcium. The delivery system protects the adsorbent and prevents its adsorbing effect in the upper gastro-intestinal (GI) tract. When the particles are made from pectin, and the beads are administered to the colon, specific pectinolytic enzymes in the colon degrade the pectin, allowing the adsorbent to be released and to be fully active. Antibiotics, toxins, and other absorbable substances present in the colon will then be inactivated by adsorption into or onto the adsorbent. | 12-31-2009 |
Pascal Huguet, Change FR
| Patent application number | Description | Published |
|---|---|---|
| 20100176802 | PORTABLE ELECTRONIC DEVICE HAVING A ROTARY UNIT - The present invention relates to a portable electronic device comprising: —a housing; —a rotary unit, which can be rotated relative to the housing, and —detection means for detecting a rotational position of the rotary unit. Said detection means comprises: —a magnetic transmitter ( | 07-15-2010 |
Thierry Huguet, Brax FR
| Patent application number | Description | Published |
|---|---|---|
| 20080251634 | Rigid Framework for Aircraft Engine Mounting Structure and Engine Mounting Structure Comprising Same - The invention relates to a rigid structure ( | 10-16-2008 |
William Huguet, Nozay FR
| Patent application number | Description | Published |
|---|---|---|
| 20110016028 | METHOD FOR BILLING SERVICES SUCH AS PUSH MAIL - A method enabling a mobile communication terminal belonging to an operator's network to access a service such as push mail, which method comprises a step of creating a first permanent private connection between a platform and the operator's network, which platform comprises a database of the users of pre-payment services and a dynamic IP address-assigning server, which method further comprises: | 01-20-2011 |
William Huguet, Velizy FR
| Patent application number | Description | Published |
|---|---|---|
| 20100285783 | METHOD OF COMMUNICATING INFORMATION FOR SUBSCRIBERS OF PREPAID SERVICES - A method enabling a mobile communication terminal ( | 11-11-2010 |