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Huang, San Francisco
Anqi Andrew Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110161987 | SCALING NOTIFICATIONS OF EVENTS IN A SOCIAL NETWORKING SYSTEM - A social networking system notification system is scaled so a user is notified of an event when a unit or level of notification utility has been reached. For the average user, a single event may be noteworthy enough for which to receive a notification. However, when this user is especially important or highly connected (or received a large number of interactions), that user will have decreasing utility for each additional comment he has received. To manage these types of situations, and avoid inundating users with notifications that are of less utility to the user, the notifications are filtered/aggregated so that these users are notified less often. The notification scheme is optimized for each user, so the user is notified only when he has reached a level of notification utility. | 06-30-2011 |
Bo Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100297777 | SUB-DIFFRACTION LIMIT IMAGE RESOLUTION AND OTHER IMAGING TECHNIQUES - The present invention generally relates to sub-diffraction limit image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined The entities may be immobilized relative to each other and/or to a common entity. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction limit resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA, a protein, a cell, a tissue, etc. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction limit image resolution, computer programs and techniques for sub-diffraction limit image resolution, methods for promoting sub-diffraction limit image resolution, methods for producing photoswitchable entities, and the like. | 11-25-2010 |
| 20110002530 | SUB-DIFFRACTION LIMIT IMAGE RESOLUTION IN THREE DIMENSIONS - The present invention generally relates to sub-diffraction limit image resolution and other imaging techniques, including imaging in three dimensions. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In some cases, the position of the entities can be determined in all three spatial dimensions (i.e., in the x, y, and z directions), and in certain cases, the positions in all three dimensions can be determined to an accuracy of less than about 1000 nm. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The emitted light may be used to determine the x and y positions of the first and second entities, for example, by determining the positions of the images of these entities, and in some cases, with sub-diffraction limit resolution. In some cases, the z positions may be determined using one of a variety of techniques that uses intensity information or focal information (e.g., a lack of focus) to determine the z position. Non-limiting examples of such techniques include astigmatism imaging, off-focus imaging, or multi-focal-plane imaging. | 01-06-2011 |
Changbo Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090213120 | Method And System For Enhanced Formulation And Visualization Rendering - An apparatus for measuring a spatially under-sampled Bidirectional Reflectance Distribution Function (BRDF) of a surface. The apparatus may comprise a first light source directed to illuminate the surface from a first illumination direction, and a plurality of sensors positioned to receive light reflected by the surface. The plurality of sensors may comprise first, second and third sensors positioned to receive light reflected by the surface in first, second and third non-coplanar directions. In various embodiments, the apparatus may also comprise a computer in communication with the plurality of sensors. The computer is configured to convert light sensed by the plurality of sensors into a first appearance property of the surface considering the first, second, and third reflectance directions. | 08-27-2009 |
Charles Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090119504 | INTERCEPTING AND SPLIT-TERMINATING AUTHENTICATED COMMUNICATION CONNECTIONS - Systems and methods are provided for enabling optimization of communications within a networked computing environment requiring secure, authenticated client-server communication connections. Optimization is performed by a pair of intermediary network devices installed in a path of communications between the client and the server. A secure, authenticated communication connection between the client and server is split-terminated at a pair of intermediary network devices by intercepting a request from the client for a client-server connection, authenticating the client at the intermediaries, establishing a first secure, authenticated connection to the client, authenticating the client or an intermediary to the server, and establishing a second secure, authenticate connection to the server. Depending on the operative authentication protocol (e.g., NTLM, Kerberos), an intermediary may interface with a domain controller, key distribution center or other entity. | 05-07-2009 |
Guo Feng Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090178089 | BROWSING AND VIEWING VIDEO ASSETS USING TV SET-TOP BOX - Roughly described, a system and method for delivering video content to a user's client device in a video-on-demand (VOD) system, which includes providing a collection of video segments, the segments having a predefined default sequence; establishing a streaming video session according to a session-oriented protocol; transmitting toward the client device a script executable by the client device, the script operable to transmit navigational codes toward the head-end equipment in response to and indicating user selection among navigational choices; beginning transmission of the video segments in the collection toward the client device in accordance with the default sequence of segments; and in response to receipt of one of the navigational codes, and without tearing down the streaming video session, altering the transmission sequence to jump to the segment that the user selected. | 07-09-2009 |
Jean Mei Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120108931 | Calibration of Analyte Measurement System - A method of calibrating an analyte measurement system is provided. | 05-03-2012 |
Min Mei Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110003384 | COMPOSITIONS AND METHODS OF USE FOR MGD-CSF IN DISEASE TREATMENT - Disclosed is a newly identified secreted molecule, identified herein as “monocyte, granulocyte, and dendritic cell colony stimulating factor” (MGD-CSF), the polypeptide sequence, and polynucleotides encoding the polypeptide sequence. Also provided is a procedure for producing the polypeptide by recombinant techniques employing, for example, vectors and host cells. Additionally, procedures are described to modify the disclosed novel molecules of the invention to prepare fusion molecules. Also disclosed are methods for using the polypeptides and active fragments thereof for treatment of a variety of diseases, including, for example, cancer, autoimmune and inflammatory diseases, infectious diseases, and recurrent pregnancy loss. | 01-06-2011 |
Xiaozhu Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090028853 | TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN ALPHAvBETA6 - The present invention relates to methods of asthma treatment and prevention using α | 01-29-2009 |
| 20110287007 | Treatment and Prevention of Chronic Asthma Using Antagonists of Integrin AlphavBeta6 - The present invention relates to methods of asthma treatment and prevention using α | 11-24-2011 |
Yadong Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090011415 | REGULATION OF NEURONAL EXPRESSION OF APOLIPOPROTEIN E - The present invention provides nucleic acids comprising a nucleotide sequence encoding an apolipoprotein E (apoE) splice variant, e.g., an unprocessed apoE, that retains intron 3; and vectors and host cells comprising same. The present invention further provides screening methods to identify agents that inhibit cleavage of intron-3 from the apoE splice variant. The present invention further provides methods of treating apoE-related neurological disorders, involving administering an agent that inhibits removal of intron-3 from a precursor apoE mRNA. | 01-08-2009 |
| 20090082271 | AGENTS THAT REDUCE APOE-INDUCED IMPAIRMENT OF MITOCHONDRIA AND METHODS OF USE THEREOF - The present invention provides isolated cells comprising a nucleic acid encoding a toxic form of apoE. The present invention further provides screening methods for identifying compounds that reduce apoE-induced impairment of mitochondrial integrity and/or function. The present invention further provides kits for use in carrying out a subject screening method. The present invention provides agents that reduce apoE-induced impairment of mitochondrial integrity and/or function; and use of such agents in the treatment of apoE-related disorders. | 03-26-2009 |
| 20090136456 | METHODS OF TREATING NEURODEGENERATIVE DISORDERS - The present invention provides a selected population of neural cells, including neural stem cells, neural progenitor cells, neural precursor cells, and progeny thereof, which neural cells are selected for an apoE4 | 05-28-2009 |
| 20110135611 | METHODS FOR TREATING APOLIPOPROTEIN E4-ASSOCIATED DISORDERS - The present disclosure provides methods of reducing apoE4 fragment-mediated toxicity of interneurons, e.g, GABAergic interneurons. The present disclosure provides methods of treating apoE4-mediated neurological disorders in an apoE4-positive individual. | 06-09-2011 |
| 20110135613 | METHODS FOR TREATING APOLIPOPROTEIN E4-ASSOCIATED DISORDERS - The present disclosure provides a method of increasing the functionality of a GABAergic interneuron in the hilus of the hippocampus of an individual having at least one apolipoprotein E4 (apoE4) allele. The method generally involves reducing tau levels in the interneuron. | 06-09-2011 |
Zhaohua Huang, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110177156 | Sterol-Modified Amphiphilic Lipids - Disclosed are sterol-modified amphiphilic lipid compounds having two or more hydrophobic tails of which at least one is a sterol. Also disclosed are the processes for the synthesis of these compounds, compositions comprising such compounds, and the use of such compounds in delivery of an agent of interest, e.g., therapeutics, imaging agents, contrast materials for ultrasound applications, vaccines, biosensors, nutritional supplements and skin care products. | 07-21-2011 |