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Huang, CT
Henry Huang, Darien, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110282731 | Systems and Methods for Optimizing Marketing Investments - Systems and methods for optimizing marketing investments are provided. The system includes a computer system in electronic communication with a business over a first communications link, means for electronically receiving marketing expenditure information from the business using the first communications link. The system executes an optimization algorithm which processes the marketing expenditure information and estimates at least one optimized future marketing expenditure for the business based upon the marketing expenditure information. the system electronically transmits the at least one optimized future marketing expenditure to a user using a second communications link, for subsequent display of the at least one optimized future marketing expenditure to the user. | 11-17-2011 |
Henry Huang, Madison, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110117094 | Reactivation of Axon Growth and Recovery in Chronic Spinal Cord Injury - Disclosed are methods of treating chronic nervous system diseases or injuries, e.g., chronic spinal cord injury, using Nogo receptor antagonists, including Nogo receptor-1 (NgR1) polypeptides, Nogo receptor-1 antibodies and antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof, and polynucleotides. Also disclosed are methods of noninvasively monitoring axonal growth during and after treatment with an axonal growth promoting agent. | 05-19-2011 |
John Huang, Hamden, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100261646 | SUSTAINED INTRAOCULAR DELIVERY OF DRUGS FROM BIODEGRADABLE POLYMERIC MICROPARTICLES - Biodegradable polymeric microparticle compositions containing one or more active agents, especially those useful for treating or preventing or one or more diseases or disorders of the eye, and methods of making and using thereof, are described. The microsphere compositions release an effective amount of the one or more active agents for a period greater than 14 days in vivo, preferably greater than 60 days in vivo, more preferably up to 73 days in vivo, more preferably greater than 90 days in vivo, even more preferably over 100 days in vivo, and most preferably greater than 107 days in vivo. In a preferred embodiment, the microparticle compositions contain one or more active agents useful for managing elevated intraocular pressure (TOP) in the eye. In one embodiment, the microspheres are formed from polylactide-co-glycolide (“PLGA”); in another embodiment, the microspheres are formed from a blend PLGA and poly lactic acid (“PLA”). Relatively hydrophilic, and preferably carboxylated, polymeric materials such as PLGA are used for a drug such as timolol maleate, which is relatively water soluble, to increase drug loading. Higher molecular weight polymers, as well as the ratio of LA (which has a longer degradation time, up to one to two years) to GA (which has a short degradation time, as short as a few days to a week), are used to provide release over a longer period of time. The combination of drug loading and release rate, as well as the minimization of initial burst release, result in prolonged release of a higher amount of drug. | 10-14-2010 |
John J. Huang, Hamden, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110206773 | SUSTAINED DELIVERY OF DRUGS FROM BIODEGRADABLE POLYMERIC MICROPARTICLES - Biodegradable polymeric microparticle compositions containing one or more active agents, especially those useful for treating or preventing or one or more diseases or disorders of the eye, and methods of making and using thereof, are described. The microsphere compositions release an effective amount of the one or more active agents for a period greater than 14 days in vivo, preferably greater than 60 days in vivo, more preferably up to 73 days in vivo, more preferably greater than 90 days in vivo, even more preferably over 100 days in vivo, and most preferably greater than 107 days in vivo. In a preferred embodiment, the microparticle compositions contain one or more active agents such as AG1478 to induce nerve regeneration, specifically regeneration of the optic nerve useful for managing elevated intraocular pressure (TOP) in the eye. | 08-25-2011 |
Rui Huang, Glastonbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110213739 | NON-INTRUSIVE LOAD MONITORING SYSTEM AND METHOD - In accordance with one embodiment, a system for non-intrusive load monitoring includes an output device, a data storage device including program instructions stored therein, a sensing device operably connected to a common source for a plurality of electrical devices, and an estimator operably connected to the output device, the data storage device, and the sensing device, the estimator configured to execute the program instructions to obtain data associated with a sensed state of the common source from the sensing device, obtain at least one model of each of the plurality of electrical devices, solve a Mixed Integer Programming problem for the at least one models over a fixed time horizon using the obtained data to determine a combination of operational stages of the plurality of electrical devices, and store operational data based on the solved Mixed Integer Programming problem. | 09-01-2011 |
Samuel Jien-Shek Huang, Mystic, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120040907 | Method of Use of Bioactive Materials - A bioactive material is made using fibroin solutions and suspensions designed to support the constructions, repair, regeneration or augmentation of bone and other tissues of the body. The fibroin solutions, suspensions, and composites can be injected to fill cavities or to replace missing tissue. After injection, the materials can produce a scaffold capable of promoting tissue regeneration while degrading. The ability to inject the fibroin solutions, suspensions and composites can reduce the need for many types of surgical procedures that are used to replace or repair bone and other tissues. The fibroin solutions and suspensions are particularly useful for methods of tissue construction and/or repair. | 02-16-2012 |
Shengqiang Huang, West Simsbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120024260 | COMBINED ENGINE BRAKING AND POSITIVE POWER ENGINE LOST MOTION VALVE ACTUATION SYSTEM - A system for actuating one or more engine valves for positive power operation and engine braking operation is disclosed. In a preferred embodiment, an exhaust valve bridge and intake valve bridge each receive valve actuations from two sets of rocker arms. Each valve bridge includes a sliding pin for actuating a single engine valve and an outer plunger disposed in the center of the valve bridge to actuate two engine valves through the bridge. The outer plunger of each valve bridge may be selectively locked to its valve bridge to provide positive power valve actuation. During engine braking, application of hydraulic pressure to the outer plungers may cause the respective valve bridges and outer plungers to unlock so that all engine braking valve actuations are provided from a rocker arm acting on one engine valve through the sliding pin. | 02-02-2012 |
Sun-Yi Huang, Stamford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090048142 | Improved Biodegradability of Antiscalant Formulations - Anionic polymers comprising. organic counterfoils exhibit improved biodegradability. The anionic polymers are useful as antiscalants. The biodegradability of an anionic polymer may be improved by replacing inorganic counterions with organic counterions. | 02-19-2009 |
Yazhong Huang, Branford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110207749 | Glycine Chroman-6-Sulfonamides for Use as Inhibitors of Diacylglycerol Lipase - The present disclosure is generally directed to compounds that can inhibit DAGLα and/or β activity, compositions comprising such compounds, and methods for inhibiting DAGLα and/or β activity. | 08-25-2011 |
| 20110207772 | Glycine Chroman-6-Sulfonamides for Use as Inhibitors of Diacylglycerol Lipase - The present disclosure is generally directed to compounds that can inhibit DAGLα and/or β activity, compositions comprising such compounds, and methods for inhibiting DAGLα and/or β activity. | 08-25-2011 |
Yingqun Huang, East Haven, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090258424 | Cellular Delivery of siRNA - The invention provides a method for delivering a nucleic acid to a cell using a targeting molecule that is bound non-covalently to the nucleic acid. Compositions and kits are also provided. | 10-15-2009 |