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Hu, NJ
Beihong Hu, Ringoes, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100099090 | BIOMARKERS AND METHODS FOR DETERMINING SENSITIVITY TO CTLA-4 ANTAGONISTS - CTLA-4 biomarkers useful in a method for predicting the likelihood that a mammal that will respond therapeutically to a method of treating cancer comprising administering an CTLA-4 antagonist, wherein the method comprises (a) measuring in the mammal the level of at least one biomarker s, (b) exposing a biological sample from the mammal to the CTLA-4 antagonist, and (c) following the exposing of step (b), measuring in the biological sample the level of the at least one biomarker, wherein an increase in the level of the at least one biomarker measured in step (c) compared to the level of the at least one biomarker measured in step (a) indicates an increased likelihood that the mammal will respond therapeutically to the method of treating cancer. | 04-22-2010 |
Chengjiu Hu, Morris Plains, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110207660 | PHARMACEUTICAL FORMULATIONS OF AN HCV PROTEASE INHIBITOR IN A SOLID MOLECULAR DISPERSION - The present invention provides pharmaceutical formulations of an HCV protease inhibitor in a solid dispersion with an excipient which provided advantageous pharmacokinetic properties for inhibiting or treating HCV infection. In preferred embodiments, the excipient is at least one polymer. The present invention also provides processes for manufacturing such formulations as well as uses of said composition for the manufacture of a medicament for treating or ameliorating one or more symptoms of HCV or disorders associated with HCV in a subject in need thereof using said formulations. | 08-25-2011 |
Chunling Hu, Piscataway, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080201591 | Method and apparatus for dynamic voltage and frequency scaling - A machine learning technique is used to improve dynamic prediction of processor utilization for multi-threaded user-level applications in a dynamic run-time environment based on processor utilization history. Processor supply voltage and processor clock frequency may be dynamically scaled based on the predicted processor utilization in order to reduce processor power consumption. | 08-21-2008 |
David Hu, South Plainfield, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100270258 | Package Feature - Formation of an “organically”-shaped feature on an otherwise abstract-shaped package. In particular, an organic or human anatomical feature is provided on an otherwise inanimate shape. More particularly, a package, such as a bottle, having a non-representational form (in other words, a package not shaped to resemble any particular form existing in nature) is provided with a feature specifically designed to resemble a form in nature or “organic” form. In an exemplary embodiment, the form in nature (or “organic” feature) is a “baby fat crease.” In particular, a crease is provided on the package to mimic the look of a baby fat crease. The geometry of the crease as well as the geometry of the package are optimized to achieve the desired organic look or effect. | 10-28-2010 |
Guohong Hu, Piscataway, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090324596 | Methods of identifying and treating poor-prognosis cancers - The present invention relates generally to methods for identifying cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis by combating metastasis and abrogating chemoresistance in cancer cells. Embodiments of the present invention provide an objective means of prognostication regarding the long-term outcome of an incident of cancer, breast cancer in particular. Therapeutic modalities include immunotherapy and anti-sense therapy. Prognosis is determined by measuring the number of copies of the metadherin gene in the patient's cells. | 12-31-2009 |
| 20100297622 | Method for high-throughput gene expression profile analysis - The present invention embraces a method for high-throughput gene profiling with high specificity and sensitivity. With this system, >1000 mRNA species can be co-amplified using gene-specific primers from a single cell. The primers are designed to amplify sequences of desirable length, which are in different exons. The exons can be either adjacent and separated by a large intron or include more than two exons. The amplified sequences are then analyzed by microarray with probes hybridizing to neighboring exons. | 11-25-2010 |
Hong Hu, Edison, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100168126 | Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine Carbomamides and Related Compounds - Cosmetic compositions comprising 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging. | 07-01-2010 |
| 20100168127 | Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine Carbomamides and Related Compounds - Cosmetic compositions comprising 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging. | 07-01-2010 |
Hsiao-Hsien Hu, Whippany, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090190472 | End-to-end network management with tie-down data integration - A method for managing tie-down information in a network management system for a telecommunications network including: providing tie-down information to the network management system associated with a plurality of tie-down demarcations using a tie-down information template comprising a plurality of tie-down information parameters associated with each of the plurality of tie-down demarcations, wherein the plurality of tie-down information parameters comprises a status; and updating the status associated with each of the plurality of tie-down demarcations based on network activity associated with the plurality of tie-down demarcations. | 07-30-2009 |
| 20090279551 | Vertical integration of network management for ethernet and the optical transport - Systems and methods are described that vertically integrate telecommunications network management across multiple transport domains and network layers to support E2E network management. Embodiments vertically integrate telecommunications network management across multiple transport layers such as physical layers (optical), data link layers (Ethernet), and upper layers (VLAN), and establish an inventory database for the plurality of transport layers in a network management OSS to integrate and correlate network alarms and other business applications. Embodiments provide a single platform for an E2E network management solution across and for multiple transport domains. | 11-12-2009 |
Jiahui Hu, Bridgewater, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100267786 | DUAL ACTING PHARMACEUTICAL COMPOSITIONS BASED ON SUPERSTRUCTURES OF ANGIOTENSIN RECEPTOR ANTAGONIST/BLOCKER (ARB) AND NE UTRAL ENDOPEPTIDASE (EP) INHIBITOR - Solid oral dosage forms, especially tablets, of a pharmaceutical composition comprising a supramolecular complex can be formed from a direct compression process or a compaction process such as roller compaction. Such solid oral dosage forms feature an immediate release profile that allows for fast release of the therapeutic agent. A particularly useful supramolecular complex is trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-(S)-3′-methyl-2′-(pentanoyl{2″-(tetrazol-5-ylate)biphenyl-4′-ylmethyl}amino)butyrate]hemipentahydrate. | 10-21-2010 |
Lin Hu, Livingston, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080213418 | ALIGN-TRANSFER-IMPRINT SYSTEM FOR IMPRINT LITHOGRPHY - An imprint system for imprint lithography comprises an alignment subsystem and an imprint subsystem. The mask (mold) and the wafer for imprinting (substrate) are align on the alignment subsystem and contacted to each other to form a mask/wafer set. The mask/wafer set is then transferred onto the imprint subsystem while alignment is maintained. The mask/wafer set is then imprinted on the imprint subsystem. During transfer, the mask/wafer set can be held in alignment by surface. The surface adhesion can be enhanced by local pressing, local heating, or both. Alternatively, the mask/wafer set can be held in alignment by clamping. Advantageously, the imprinting is effected by fluid pressure imprinting. | 09-04-2008 |
| 20100119641 | IMPRINT LITHOGRAPHY WITH IMPROVED SUBSTRATE/MOLD SEPARATION - In imprint lithography, a mold having a pattern of projecting and recessed regions is pressed into a moldable surface on a substrate. The thus-imprinted moldable surface is permitted to at least partially harden to retain the imprint, and the substrate and mold are separated. In accordance with the invention, the substrate is separated from the mold by bending laterally distal regions (regions away from the center toward the edges) of the mold transversely away from the interface and transversely restraining the substrate. The mold can then be easily separated from the substrate by transverse displacement. The separation can be facilitated by providing a mold having a lateral dimension that on at least two sides extends beyond the corresponding lateral dimension of the substrate. Alternatively, the substrate can have a greater lateral extent than the mold, and the mold can be restrained. The distal regions of the substrate can be bent in the transverse direction. Apparatus for effecting such separation is also described. | 05-13-2010 |
| 20100289184 | Die Imprint By Double Side Force-Balanced Press For Step-And-Repeat Imprint Lithography - In accordance with the invention, step-and-repeat imprint lithography is effected by applying balanced pressing forces from both sides of a substrate. The pressing forces are substantially equal in amplitude and opposite in direction. With the pressing forces thus balanced, the fixture that steps and holds the substrate does not bear the load of imprinting. The balance allows use of a high resolution aligning stage to carry the substrate and to maintain high accuracy of positioning without being shifted by change of load. With this method, sufficient imprint pressure can be used to obtain high quality patterning, a thin and uniform residual layer, and a high fidelity pattern. | 11-18-2010 |
| 20110155060 | Method And Apparatus To Apply Surface Release Coating For Imprint Mold - A surface coating apparatus for preparing a work piece having a working surface for imprint lithography, wherein the work piece comprises either a mold or a substrate. The apparatus includes a vacuum chamber and a generator to produce chemical reaction radicals for cleaning the working surface. The generator may be located inside said vacuum chamber and connected to an inner surface of said vacuum chamber or external to the vacuum chamber and connected thereto via suitable couplings. A fixture within the vacuum chamber is configured to hold the work piece with the working surface accessible by the chemical reaction radicals, and a means is provided for depositing a molecular layer of surfactant on the working surface inside the vacuum chamber. | 06-30-2011 |
| 20110180965 | FAST NANOIMPRINTING APPARATUS USING DEFORMALE MOLD - The invention disclosed apparatuses and methods to do nanoimprint lithography using a deformable mold. Generally, the apparatus has a chamber with a transparent section on its top wall, which is capable of vacuuming and pressurizing. The deformable mold fixed firmly onto a hollow mold holder around its full periphery is attached to top inner surface of the chamber and positioned underneath the transparent section. The central area of the mold is freely accessible from underneath through the opening of the mold holder. An enclosed volume referring to mold mini-chamber is formed between the mold/holder and top wall of the chamber. Inside chamber, a stage assembly is installed. A chuck to vacuumly hold a substrate is mounted on top of the stage assembly. At beginning of the imprinting, the substrate with a layer of resist is positioned underneath the mold at a predetermined gap between them. Then, the substrate is moved up to contact with the mold either under vacuum or under atmosphere. The substrate and mold may be pressed further by introducing higher pressure inside the chamber. After consolidating the resist, the substrate is separated from the mold by either direct pull-down enabled by stage movement or deforming the mold enabled by differential pressure between the mold mini-chamber and the bulk volume of the chamber, or mixing of both. | 07-28-2011 |
Longqin Hu, Piscataway, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100075927 | CHEMOTHERAPEUTIC CONJUGATES AND METHODS OF USE - Chemotherapeutic conjugates of a peptide substrate to a phosphoramide chemotherapeutic agent in which a peptide substrate is covalently linked to the chemotherapeutic agent by a linker with an aminoarylmethyl or aminoheteroaryl moiety, wherein the linking of the peptide to the chemotherapeutic agent inhibits the cytotoxic activity of the chemotherapeutic agent, the peptide is a substrate for proteolytic cleavage by a tumor-specific enzyme; and the linker is capable of undergoing 1,6-elimination in vivo upon cleavage of the peptide substrate. Methods for synthesizing and methods of using the conjugates are also disclosed. | 03-25-2010 |
Longsheng Hu, Piscataway, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110144141 | Hair Growth and/or Regrowth Compositions - The present disclosure relates to compositions containing certain pyrimidine compounds such as minoxidil and/or certain pyrimidine sulfate (inner salt) compounds such as minoxidil sulfate and especially compositions containing pyrimidine compounds in combination with an admixtures comprising at least one antioxidant, at least one organic acid and a select fatty acid mixture. The present disclosure also relates to use of the compositions to grow and/or regrow hair and/or prevent hair loss in mammals and particularly in humans. | 06-16-2011 |
| 20110144142 | Methods of Reducing Hair Loss and/or Facilitating Hair Growth and/or Regrowth - The present disclosure relates to methods of retarding hair loss or facilitating hair growth and/or regrowth. More specifically, the present disclosure relates to methods of using the disclosed compositions to increase the rate of terminal hair growth and/or regrowth in a mammal. | 06-16-2011 |
Mengwei Hu, Washington, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100048601 | HYDROCHLORIDE SALTS OF 8-[-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one AND PREPARATION PROCESS THEREFOR - Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-S[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same. | 02-25-2010 |
Mengwei Hu, Washington Township, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080279822 | Crystalline Polymorphs of a CXC-Chemokine Receptor Ligand - The present invention relates to four distinct crystalline polymorphs of a monohydrate of Compound A having the following chemical structure: | 11-13-2008 |
Qingyuan Hu, East Brunswick, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100227758 | Alumina-Based Perovskite Catalysts and Catalyst Supports - An alumina-based perovskite is formed by mixing a lanthanide source with a transitional alumina to form a dual-phase composition comprising in situ formed LnAlO | 09-09-2010 |
Shou-Ih Hu, New Providence, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090130113 | Compositions and methods for use for antibodies against sclerostin - The present invention relates to antibodies against sclerostin and compositions and methods of use for said antibodies to treat disease related to bone abnormalities such as osteoporosis. An embodiment of the invention herein provides an antibody or a functional protein comprising an antigen-binding portion of said antibody for a target in sclerostin polypeptide, characterized in that the antibody or functional protein specifically binds to sclerostin polypeptide and can increase at least one of bone formation, bone mineral density, bone mineral content, bone mass, bone quality and bone strength in a mammal. | 05-21-2009 |
| 20090192087 | Methods and Compositions Using Klotho-FGF Fusion Polypeptides - The present invention is directed to methods, kits and compositions for preventing or treating age-related conditions or metabolic disorders. The Klotho fusion polypeptides of the invention include at least a Klotho protein or an active fragment thereof. The Klotho fusion proteins are useful in the treatment and prevention of a variety of age-related conditions and metabolic disorders. | 07-30-2009 |
| 20110052592 | Compositions and Methods for Use for Antibodies Against Sclerostin - The present invention relates to antibodies against sclerostin and compositions and methods of use for said antibodies to treat a pathological disorder that is mediated by sclerostin or disease related to bone abnormalities such as osteoporosis. | 03-03-2011 |
Shou-Ih Hu, East Hanover, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100215657 | Methods and Compositions Using Klotho-FGF Fusion Polypeptides - The present invention is directed to methods, kits and compositions for preventing or treating age-related conditions or metabolic disorders. The Klotho fusion polypeptides of the invention include at least a Klotho protein or an active fragment thereof. In one embodiment, the fusion polypeptide comprises a Klotho polypeptide, a FGF (such as FGF23) and (optionally) a modified Fc fragment. The Fc fragment can, for example, have decreased binding to Fc-gamma-receptor and increased serum half-life. The Klotho fusion proteins are useful in the treatment and prevention of a variety of age-related conditions and metabolic disorders. In another embodiment, the fusion polypeptide comprises a FGF (such as FGF23) and a modified Fc fragment. | 08-26-2010 |
Ting-Chen Hu, Edison, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090324250 | Wireless transmitters - A wireless transmitter includes an optical modulator, an optical power splitter, a plurality of electrical drivers, and a plurality of antennas. The optical power splitter has a plurality of optical outputs and has an optical input connected to receive a modulated optical carrier from the optical modulator. Each driver is configured to detect a portion of the modulated optical carrier output by one of the optical outputs of the optical power splitter. Each antenna is connected to be driven by one of the electrical drivers. | 12-31-2009 |
| 20100054761 | Monolithic coherent optical detectors - An optical receiver has a monolithically integrated electrical and optical circuit that includes a substrate with a planar surface. Along the planar surface, the monolithically integrated electrical and optical circuit has an optical hybrid, one or more variable optical attenuators, and photodetectors. The optical hybrid is connected to receive light beams, to interfere light of said received light beams with a plurality of relative phases and to output said interfered light via optical outputs thereof. Each of the one or more variable optical attenuators connects between a corresponding one of the optical outputs and a corresponding one of the photodetectors. | 03-04-2010 |
| 20110149369 | PHOTONIC MATCH FILTER - An optical path is configured to propagate an input optical signal. A plurality of electrodes are configured to produce a plurality of discrete phase shifts on the optical signal. An output optical signal is phase-shifted with respect to the input optical signal by a sum of the plurality of discrete phase shifts. | 06-23-2011 |
| 20110149370 | Photonic Technique For Generating Arbitrary Waveforms - In a radio frequency (RF)-photonic arbitrary waveform generator (AWG), an optical carrier signal is phase-modulated using an arbitrary waveform optical phase generator (AWPOG), which may include, e.g., sequential optical phase modulators. The phase-modulated optical signal is combined with a version of the optical carrier signal to yield an optical waveform, whose amplitude varies with a phase shift introduced by the AWPOG to the optical carrier signal. By manipulating electrical inputs to the AWPOG which control the phase shift, the optical waveform can be arbitrary shaped. The optical waveform may then be converted to an electrical waveform having a radio frequency. | 06-23-2011 |
Wenhao Hu, Princeton, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100076191 | PROCESS FOR PREPARING TRIAZOLE SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES AND NOVEL SALT FORMS PRODUCED THEREIN - A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided. | 03-25-2010 |
Yaping Hu, Highland Park, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110045477 | HUMAN SKIN EXPLANT CULTURE SYSTEM AND USE THEREFOR - The present invention features a human skin explant culture system and uses thereof. | 02-24-2011 |
Yifan Hu, Mountain Lakes, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100134497 | Methods, Systems, and Products for Graphing Data - Methods, systems, and products are disclosed for graphing data. A layout is retrieved that comprises locations for vertices. A proximity location is generated for each vertex. Each vertex's location from the layout is merged with each vertex's proximity location. A cost function associated with the layout is minimized. | 06-03-2010 |
| 20100149186 | Methods, Systems, and Products for Graphing Data - Methods, systems, and products are disclosed for graphing data. A layout is retrieved that comprises locations for vertices. A proximity graph is generated using triangulation. Nodal overlaps are removed. | 06-17-2010 |
| 20110134128 | Visualization and Representation of Data Clusters and Relations - Relational data can be visualized in a map representation. A plurality of vertices and edges are determined based on a set of data identifying objects (i.e., vertices) and relationships (i.e., edges). The vertices and edges are embedded in a planar graph and a Voronoi diagram is generated based at least the plurality of vertices within a set of bounding-points located at least a distance away from the vertices of the map. A bounding-box is associated with each of the vertices, and a set of points generated along each bounding-box. The Voronoi diagram is generated based on the vertices and the set of points of each bounding-box. Each resulting Voronoi cell associated with a common vertex is merged to form a plurality of common cells (i.e., map). The size of each bounding-box can correlate to the importance of its associated vertex, and the points along the bounding-box can be randomly perturbed. | 06-09-2011 |
| 20110153663 | RECOMMENDATION ENGINE USING IMPLICIT FEEDBACK OBSERVATIONS - Systems and methods to provide a recommendation engine that uses implicit feedback observations are provided. A particular method includes receiving accessing data comprising a plurality of implicit feedback observations for a plurality of users. The plurality of users includes a first user that requested a recommendation. Each implicit feedback observation is associated with a particular user and a particular item of a plurality of items. The method includes determining a plurality of preference ratings and a plurality of confidence ratings for each user of the plurality of users for each item based on the plurality of implicit feedback observations. The method includes generating a recommendation list of one or more of the plurality of items for the first user based on the plurality of preference ratings and the plurality of confidence ratings. | 06-23-2011 |
Yongbo Hu, River Edge, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080293712 | Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof - The present invention relates to Benzo[c][2,7]naphthyridine Derivatives, compositions comprising an effective amount of a Benzo[c][2,7]naphthyridine Derivative, methods for treating or preventing a proliferative disorder or an autoimmune disease, comprising administering to a subject in need thereof an effective amount of a Benzo[c][2,7]naphthyridine Derivative, methods for modulating PDK-1 activity, PKA activity, Akt activity, S6K activity, or PKC activity, comprising administering to a subject in need thereof an effective amount of a Benzo[c][2,7]naphthyridine Derivative. The invention also relates to processes for preparing a Benzo[c][2,7]naphthyridine Derivative. | 11-27-2008 |
Yuhong Hu, Belle Mead, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100210163 | HOT MELT ADHESIVES CONTAINING STYRENE BUTADIENE BLOCK COPOLYMER - Hot melt adhesive compositions containing hyper-branched SBS block copolymers and end use applications thereof. The hyper-branched SBS is characterized in having a ratio between light-scattering molecular weight (of non-di-block polymer) and GPC molecular weight (of non-di-block polymer) greater than 1.4 and having ratio between light scattering molecular weight molecular weight (of non-di-block polymer) and light scattering molecular weight molecular weight (of di-block polymer) greater than 5. The ratio between light scattering molecular weight MW (of non-di-block polymer) and light scattering molecular weight MW (of di-block polymer) also defines the number of arms for the hyper branched structure. The weight average molecular weight of each arm of the hyper-branched SBS block copolymer is less than about 100,000. These are multipurpose adhesives finding utility as packaging, labeling, construction and positioning adhesives, and are particularly well suited for use as elastic attachment adhesives in the manufacture of elastic-containing products, such as disposable absorbent elastic articles. | 08-19-2010 |
Zhicheng Hu, Edison, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080226514 | Exhaust Gas Treatment Catalyst - Provided are an exhaust treatment catalyst and an exhaust article containing the catalyst. The catalyst comprises a carrier; a first layer deposited on the carrier, said first layer comprising substantially only at least one refractory metal oxide; a second layer deposited on the first layer, said second layer comprising substantially only at least one oxygen storage component and at least one binder therefore; and a third layer deposited on the second layer, said third layer comprising at least one layer of one or more platinum group metal components supported on a refractory metal oxide support. | 09-18-2008 |
| 20090042722 | Manufacture of Exhaust Articles for Internal Combustion Engines - Provided are methods for manufacturing a base metal undercoat containing catalyst and an exhaust article containing the catalyst. The catalyst contains a base metal undercoat with an oxygen storage component, substantially free of platinum group metal components, and at least one catalytic layer. | 02-12-2009 |