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Hu, NC

Hong Hu, Chapel Hill, NC US

Patent application numberDescriptionPublished
20100087431TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS - The present invention provides triazolyl aminopyrimidine compounds useful in the treatment of cancer.04-08-2010
20100130466TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS - The present invention provides triazolyl aminopyrimidine compounds useful in the treatment of cancer.05-27-2010

Jennie (jing) Hu, Cary, NC US

Patent application numberDescriptionPublished
20110035257Systems And Methods For Generating Planograms In The Presence Of Multiple Objectives - Systems and methods for an item placement configuration optimization are provided. A system and method can include receiving a first selection including two or more first items corresponding to a first level in an item placement configuration. A first score is determined for the first selection by applying an algorithm to data corresponding to the first items. A second selection including two or more second items and corresponding to a second level in the item placement configuration is received. A second score for the second selection is determined by applying an algorithm to the first score and data corresponding to the second items.02-10-2011

Peiqi Hu, Chapel Hill, NC US

Patent application numberDescriptionPublished
20080207519Inhibition of Hsp27 Phosphorylation for the Treatment of Blistering Disorders - A method of treating a blistering disorder, which includes administering to a target tissue in a subject in need thereof an effective amount of a composition that inhibits activation of the HSP27 phosphorylation pathway.08-28-2008

Xin-Hua Hu, Greenville, NC US

Patent application numberDescriptionPublished
20090103085Method and Apparatus for Spectrophotometric Characterization of Turbid Materials - Method and apparatus for spectrophotometric characterization of turbid materials are provided. An incident light beam is used to illuminate a turbid material sample and optical signals of coherent reflectance, diffuse reflectance, collimated transmittance and diffuse transmittance are measured from the sample as functions of wavelength. The following optical parameters are determined as functions of wavelength for spectrophotometric characterization of the turbid material sample in the spectrum of interest: absorption coefficients μ04-23-2009
20110090500FLOW CYTOMETER APPARATUS FOR THREE DIMENSIONAL DIFRACTION IMAGING AND RELATED METHODS - A flow cytometer assembly includes a fluid controller configured to form a hydrodynamically focused flow stream including an outer sheath fluid and an inner core fluid. A coherent light source is configured to illuminate a particle in the inner core fluid. A detector is configured to detect a spatially coherent distribution of elastically scattered light from the particle excited by the coherent light source. An analyzing module configured to extract a three-dimensional morphology parameter of the particle from a spatially coherent distribution of the elastically scattered light.04-21-2011

Yuequan Hu, Morrisville, NC US

Patent application numberDescriptionPublished
20090187925Driver that efficiently regulates current in a plurality of LED strings - A light-emitting diode (LED) driver according to the present invention consists of a voltage pre-regulator and multiple linear current regulators with an adaptively-controlled drive voltage. In this LED driver, the efficiency maximization is achieved by eliminating the sensing of the voltage drops across the linear regulators, i.e., by removing the external voltage feedback for the adjustment of the output voltage of the pre-regulator. In the LED driver of the present invention, the self-adjustment of drive voltage is achieved by relying on a relatively strong dependence between the gate-to-source and drain-to-source voltages of a current-regulating transistor, e.g., a MOSFET, operating in the linear region. The driver powers all LEDs in a string with a constant current and provides consistent illumination and optimum operating efficiency at low cost over a wide range of input/output voltage and temperature.07-23-2009
20100253234POWER SUPPLY HAVING AN AUXILIARY POWER STAGE FOR SUSTAINING SUFFICIENT POST IGNITION CURRENT IN A DC LAMP - The current invention provides a power supply that includes an igniter that generates an ignition voltage for igniting a DC lamp; an auxiliary power stage that outputs an auxiliary voltage for sustaining sufficient current in the DC lamp after the DC lamp is ignited; a voltage conversion stage coupled to the auxiliary power stage and generating a voltage at a level that is higher than the auxiliary voltage; and a switch that couples the auxiliary voltage to the DC lamp and the voltage conversion stage for a predefined period of time.10-07-2010

Patent applications by Yuequan Hu, Morrisville, NC US

Yunfu Hu, Chapel Hill, NC US

Patent application numberDescriptionPublished
20100279956Biomarkers For Fatty Liver Disease And Methods Using The Same - The present invention provides various biomarkers of fatty liver disease, including steatosis and steatohepatitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of fatty liver disease, methods of determining predisposition to fatty liver disease, methods of monitoring progression/regression of fatty liver disease, methods of assessing efficacy of compositions for treating fatty liver disease, methods of screening compositions for activity in modulating biomarkers of fatty liver disease, methods of treating fatty liver disease, as well as other methods based on biomarkers of fatty liver disease.11-04-2010

Yun Fu Hu, Chapel Hill, NC US

Patent application numberDescriptionPublished
20090155826Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same - Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy.06-18-2009

Zhiyuan Hu, Apex, NC US

Patent application numberDescriptionPublished
20090172835FLAX (LINUM USITATISSIMUM L.) SEED-SPECIFIC PROMOTORS - The present invention is directed to promoters of flax conlinin and ω-3 desaturase genes. The promoters guide high levels of the expression exclusively in flax developing seeds. This specific expression pattern concomitant with the biosynthesis of storage lipids and proteins make these promoters particularly useful for seed-specific modification of fatty acid and protein compositions in plant seeds.07-02-2009
20100221722METHODS FOR EVALUATING BREAST CANCER PROGNOSIS - Methods for diagnosing and for evaluating the prognosis of a cancer patient, particularly a breast cancer patient, are provided. The methods include determining expression levels of at least five biomarkers in a body sample including a cancer cell from the patient, where expression levels of the biomarkers are indicative of cancer prognosis. Overexpression of the biomarkers of the invention is indicative of a poor prognosis. In some embodiments, the body sample is a breast tissue sample, particularly a primary breast tumor sample. The methods of the invention can be used in combination with assessment of conventional clinical factors and permit a more accurate evaluation of breast cancer prognosis.09-02-2010

Patent applications by Zhiyuan Hu, Apex, NC US