Patent application number | Description | Published |
20120101790 | EMBROIDERY IMAGE RENDERING USING PARAMETRIC TEXTURE MAPPING - Rendering methods, systems, and computer-readable media for rendering a simulated embroidery design image based on an embroidery design are presented. Given an embroidery design comprising a plurality of stitch representations and a lighting angle for the simulated embroidery design image, embodiments process the stitch representations to determine a stitch length and lighting angle and select from a stitch image database a stitch image corresponding to the stitch length and lighting angle, and place the selected stitch on a rendering canvas in a position corresponding to the stitch position indicated by the stitch representation. When rendered, all of individual stitch image on the rendering canvas appear to be illuminated from the same direction. | 04-26-2012 |
20120203371 | METHOD AND SYSTEM FOR CONVERTING AN IMAGE TO A COLOR-REDUCED IMAGE MAPPED TO EMBROIDERY THREAD COLORS - Methods and systems are presented for converting an image to a color-reduced image suitable for embroidery and having colors mapped only to available embroidery thread colors. Pixel color values in the image are snapped to a nearest color in a predetermined reduced set of colors that correspond to embroidery thread colors. The image is then color-reduced by iteratively identifying possible pairs of colors in the color-reduced image and merging at least one identified color pair based on color similarity and edge characteristics until the total number of colors in the color-reduced image is not greater than the predetermined maximum color count. | 08-09-2012 |
20120256948 | METHOD AND SYSTEM FOR RENDERING IMAGES IN SCENES - Systems and methods are described for generating and using a flexible scene framework to render dynamically-generated content within contextual scenes. | 10-11-2012 |
20120259727 | METHOD AND SYSTEM FOR PERSONALIZING IMAGES RENDERED IN SCENES FOR PERSONALIZED CUSTOMER EXPERIENCE - Systems and methods are described for generating and using a flexible scene framework to render dynamically-generated content within contextual scenes to personalize a customer's web experience. | 10-11-2012 |
20130335437 | METHODS AND SYSTEMS FOR SIMULATING AREAS OF TEXTURE OF PHYSICAL PRODUCT ON ELECTRONIC DISPLAY - Design images are inserted into scene rendered animations to depict and preview a design at different lighting angles. In an embodiment, the scene rendered animations use real images (i.e., photographs) of real finishes (such as foil, spot gloss, vinyl, etc.) that will be used in the secondary finish regions of a physical product incorporating the design. The animation facilitates an accurate rendering and depicts a natural appearance of the product as light moves across the product in an animated sequence. Because the appearance of the secondary finish is both natural and accurate, the simulated depiction of the product provides a more realistic expectation of how the final product with the design implemented thereon will look, thereby improving the matching of user expectations with the realities of the physical product. | 12-19-2013 |
20140279271 | Systems and Methods for Configuring a Group Order and Automatic Generation of Group Order Notification and Feedback Conforming to Pre-Specified Feedback Constraints - Systems, methods and tools facilitate efficient and convenient e-commerce based group ordering. A group order organizer tool allows a group order organizer to create and configure a group order, specify group members, specify and configure information to be solicited from group members, and customize various details of the group order. The group order tool automatically generates member-specific group order notification documents containing member-specific input controls to allow individual group members to input solicited information. Group order notification and management tools send out the group order notification documents to the group members and manage the responses. | 09-18-2014 |
Patent application number | Description | Published |
20140189896 | CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION - The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR/Cas system. | 07-03-2014 |
20140242664 | ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION - The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR-Cas system. | 08-28-2014 |
20140273232 | ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION - The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR-Cas system. | 09-18-2014 |
Patent application number | Description | Published |
20090240325 | Implantable Medical Device Coatings With Improved Mechanical Stability - Implantable medical device coatings that have improved mechanical stability and medical devices coated with such coatings are disclosed. | 09-24-2009 |
20120270979 | BLEND COMPOSITION, FLEXIBLE TUBING MATERIAL AND METHOD OF MAKING THE BLEND - A composition includes a blend of (a) a multi-block copolymer including at least one block of an elastomeric polymer and at least one block of a first polymer including a chiral polymer having a stereo isomeric configuration; and (b) a second polymer including an anti-chiral polymer corresponding to the chiral polymer in (a), wherein the second polymer includes an opposite handed stereo isomeric configuration to the chiral polymer in (a); wherein the blend of the chiral polymer and the anti-chiral polymer form stereo complex sites. A flexible tubing material further includes the blend. In an embodiment, a method of making the blend material is also provided. | 10-25-2012 |
20120328770 | Methods For Modulating The Release Rate Of A Drug-Coated Stent - Methods for modulating the release rate of a drug coated stent are disclosed. | 12-27-2012 |
20130005878 | MELT PROCESSABLE COMPOSITION AND METHOD OF MAKING - A composition includes a) a melt processable polymer including at least one chemical moiety having a partial charge; and b) a nucleating agent having a surface charge that is opposite the partial charge of the chemical moiety of the polymer, wherein the nucleating agent accelerates the rate of crystallization of the melt processable polymer; wherein the nucleating agent has a melting point greater than the melting point of the melt processable polymer. In an embodiment, a method of making the composition is also provided. | 01-03-2013 |
20140186563 | STABILIZED POLYESTER BASED COMPOSITIONS - A polyester or polyester copolymer based composition, such as a polylactic acid based composition, is provided herein. The polyester or polyester copolymer based composition may include a plasticizer, such as an ether based, an ester based, and/or an ether-ester based plasticizer. | 07-03-2014 |
Patent application number | Description | Published |
20080268480 | Methods of Evaluating Baff - The present disclosure provides compositions and methods relating to the evaluation of BAFF in a biological sample from a subject. | 10-30-2008 |
20090220998 | Platelet Aggregation Assays - The present invention provides methods of determining platelet aggregation, methods of determining susceptibility to clotting upon administration of a CD40L-binding moiety, and kits related thereto. | 09-03-2009 |
20090324602 | ANTI-FN14 ANTIBODIES AND USES THEREOF - Antibodies and antibody fragments that bind to the receptor Fn14 and induce or enhance cell killing of Fn14-expressing cancer cells are disclosed. Also disclosed are methods of using the antibodies and antibody fragments to induce death of a tumor cell and treat disorders and in a subject. | 12-31-2009 |
20100104573 | BINDING PROTEINS, INCLUDING ANTIBODIES, ANTIBODY DERIVATIVES AND ANTIBODY FRAGMENTS, THAT SPECIFICALLY BIND CD154 AND USES THEREOF - This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions. | 04-29-2010 |
20100184951 | Truncated BAFF Receptors - The disclosure provides a non-naturally occurring BAFF-R glycoprotein having a deletion in the extracellular domain which results in an altered O-linked glycosylation pattern. The disclosure also provides methods and pharmaceutical compositions for treating B-cell- and T-cell-mediated disorders. | 07-22-2010 |
20100330066 | Methods for Use with Baff Antagonists - BAFF plays a central role in acquired immunity. The disclosure identifies BAFF-responsive genes that are substantially upregulated by administration of BAFF and substantially downregulated by treatment with a BAFF antagonist. Specific genes are: NF-κB2, CD23, H2-Mβ (the beta chain of H2-DM), Fig-1, and OBF-1. The disclosure provides methods and compositions for: monitoring the activity of a BAFF antagonist in a mammal; monitoring BAFF activity in a mammal; identifying a mammal to be treated with a BAFF antagonist; and related uses. Such methods include detecting one or more molecules selected from the group consisting of Fig-1 molecule, OBF-1 molecule, and H2-Mβ molecule in a biological sample of the mammal, and optionally further detecting NF-κB2 molecule and/or CD23 molecule in the biological sample. | 12-30-2010 |
20110311530 | TRUNCATED BAFF RECEPTORS - The disclosure provides a non-naturally occurring BAFF-R glycoprotein having a deletion in the extracellular domain which results in an altered 0-linked glycosylation pattern. The disclosure also provides methods and pharmaceutical compositions for treating B-cell- and T-cell-mediated disorders. | 12-22-2011 |
20120082661 | ANTI-BCMA ANTIBODIES - This invention provides antibodies that recognize the B Cell Maturation Antigen (BCMA) and that bind naïve B cells, plasma cells, and/or memory B cells. The invention further provides methods for depleting naïve B cells, plasma cells, and memory B cells, and for treating B cell-related disorders, including lymphomas and autoimmune diseases. | 04-05-2012 |
20120231481 | METHODS OF EVALUATING BAFF - The present disclosure provides compositions and methods relating to the evaluation of BAFF in a biological sample from a subject. | 09-13-2012 |
20130045219 | BINDING PROTEINS, INCLUDING ANTIBODIES, ANTIBODY DERIVATIVES AND ANTIBODY FRAGMENTS, THAT SPECIFICALLY BIND CD154 AND USES THEREOF - This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions. | 02-21-2013 |
20130177558 | Method of Treating Immunological Disorders by Administering Truncated BAFF Receptors - The disclosure provides a non-naturally occurring BAFF-R glycoprotein having a deletion in the extracellular domain which results in an altered O-linked glycosylation pattern. The disclosure also provides methods and pharmaceutical compositions for treating B-cell- and T-cell-mediated disorders. | 07-11-2013 |
20130189713 | PLATELET AGGREGATION ASSAYS - The present invention provides methods of determining platelet aggregation, methods of determining susceptibility to clotting upon administration of a CD40L-binding moiety, and kits related thereto. | 07-25-2013 |
20130196351 | Methods of Evaluating BAFF - The present disclosure provides compositions and methods relating to the evaluation of BAFF in a biological sample from a subject. | 08-01-2013 |
20140213470 | METHODS FOR USE WITH BAFF ANTAGONISTS - BAFF plays a central role in acquired immunity. The disclosure identifies BAFF responsive genes that are substantially upregulated by administration of BAFF and substantially downregulated by treatment with a BAFF antagonist. Specific genes are NF-κB2, CD23, H2-Mβ (the beta chain of H2-DM), Fig-1, and OBF-1. The disclosure provides methods and compositions for monitoring the activity of a BAFF antagonist in a mammal; monitoring BAFF activity in a mammal; identifying a mammal to be treated with a BAFF antagonist; and related uses. Such methods include detecting one or more molecules selected from the group consisting of Fig-1 molecule, OBF-1 molecule, and H2-Mβ molecule in a biological sample of the mammal, and optionally further detecting NF-κB2 molecule and/or CD23 molecule in the biological sample. | 07-31-2014 |
20140273019 | Methods of Evaluating BAFF - The present disclosure provides compositions and methods relating to the evaluation of BAFF in a biological sample from a subject. | 09-18-2014 |
20140302016 | BINDING PROTEINS, INCLUDING ANTIBODIES, ANTIBODY DERIVATIVES AND ANTIBODY FRAGMENTS, THAT SPECIFICALLY BIND CD154 AND USES THEREOF - This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions. | 10-09-2014 |
20150023961 | METHODS OF MODULATING IMMUNOLOGICAL RESPONSES BY ADMINISTERING TRUNCATED BAFF RECEPTORS - The disclosure provides a non-naturally occurring BAFF-R glycoprotein having a deletion in the extracellular domain which results in an altered O-linked glycosylation pattern. The disclosure also provides methods and pharmaceutical compositions for treating B-cell- and T-cell-mediated disorders. | 01-22-2015 |
Patent application number | Description | Published |
20130150693 | CATHETER BALLOON METHODS AND APPARATUS EMPLOYING SENSING ELEMENTS - An apparatus for medical diagnosis and/or treatment is provides. The apparatus includes a flexible substrate forming an inflatable body and a plurality of sensing elements disposed on the flexible substrate. The plurality of sensing elements are disposed about the inflatable body such that the sensing elements are disposed at areas of minimal curvature of the inflatable body in a deflated state. | 06-13-2013 |
20130200268 | ELECTRONICS FOR DETECTION OF A PROPERTY OF A SURFACE - Apparatus are provided for monitoring a condition of a surface based on a measurement of a property of the surface using a sensor. In an example, the property is performed using an apparatus disposed above the tissue, where the apparatus includes at least one coil structure formed from a conductive material, at least one other component, and at least one cross-link structure physically coupling a portion of the at least one coil structure to a portion of the at least one other component, the at least one cross-link structure being formed from a flexible material. The at least one other component can be a sensor component or a processor unit. | 08-08-2013 |
20130245388 | ELECTRONICS FOR DETECTION OF A CONDITION OF TISSUE - Apparatus are provided for monitoring a condition of a tissue based on a measurement of an electrical property of the tissue. In an example, the electrical property of the tissue is performed using an apparatus disposed above the tissue, where the apparatus includes at least two conductive structures, each having a non-linear configuration, where the at least two conductive structures are disposed substantially parallel to each other. In another example, the electrical property of the tissue is performed using an apparatus disposed above the tissue, where the apparatus includes at least one inductor structure. | 09-19-2013 |
20140012160 | CATHETER BALLOON EMPLOYING FORCE SENSING ELEMENTS - An apparatus for medical diagnosis and/or treatment is provides. The apparatus includes a flexible substrate forming an inflatable body and a plurality of force sensing elements disposed on the flexible substrate. The plurality of force sensing elements are disposed about the inflatable body such that the force sensing elements are disposed at areas of minimal curvature of the inflatable body in a deflated state. | 01-09-2014 |
20140012242 | CATHETER DEVICE INCLUDING FLOW SENSING - Devices and methods are provided for performing an ablation procedure on tissue with flow monitoring using flow sensors. The devices include a catheter, and at least one flow sensor disposed on the catheter, and a component for applying the ablation procedure. An assessment module provides an indication of the efficacy of the ablation procedure based on the flow measurement from the flow sensor. | 01-09-2014 |
20140022746 | STRAIN RELIEF STRUCTURES FOR STRETACHBLE INTERCONNECTS - Intersection structures are provided to reduce a strain in a conformable electronic system that includes multi-level arrangements of stretchable interconnect structures. Bypass regions are formed in areas of the stretchable interconnect structures that may ordinarily cross or pass each other. The bypass regions of the stretchable interconnects are disposed relative to each other such that the intersection structure encompasses at least a portion of the bypass regions of each stretchable interconnect structure. The intersection structure has elastic properties that relieve a mechanical strain on the bypass regions during stretching at least one of the stretchable interconnect structures. | 01-23-2014 |
20140240932 | STRAIN ISOLATION STRUCTURES FOR STRETCHABLE ELECTRONICS - Buffer structures are provided that can be used to reduce a strain in a conformable electronic system that includes compliant components in electrical communication with more rigid device components. The buffer structures are disposed on, or at least partially embedded in, the conformable electronic system such that the buffer structures overlap with at least a portion of a junction region between a compliant component and a more rigid device component. The buffer structure can have a higher value of Young's modulus than an encapsulant of the conformable electronic system. | 08-28-2014 |