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Hsieh, MA
Chung-Ming Hsieh, West Roxbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080311581 | FUNCTIONAL POLYMORPHISMS OF THE INTERLEUKIN-1 LOCUS AFFECTING TRANSCRIPTION AND SUSCEPTIBILITY TO INFLAMMATORY AND INFECTIOUS DISEASES - The invention provides methods and reagents for detecting a polymorphism associated with in an upstream region of the interleukin-1β (IL-B) gene (IL-1B (−3737)) that affects transcription of the gene and susceptibility to inflammatory and infectious diseases such as diffuse coronary artery disease. | 12-18-2008 |
| 20100279280 | FUNCTIONAL POLYMORPHISMS OF THE INTERLEUKIN-1 LOCUS AFFECTING TRANSCRIPTION AND SUSCEPTIBILITY TO INFLAMMATORY AND INFECTIOUS DISEASES - The invention provides methods and reagents for detecting a polymorphism associated with in an upstream region of the interleukin-1 beta (IL-B) gene (IL-1B (−3737)) that affects transcription of the gene and susceptibility to inflammatory and infectious diseases such as periodontal disease and Alzheimer's disease. | 11-04-2010 |
Frank Hsieh, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100267061 | DETECTING PHOSPHOLIPIDOSIS AND DIAGNOSING LYSOSOMAL STORAGE DISORDERS - Disclosed are methods for evaluating the potential or activity of a test compound to induce phospholipidosis in a target subject, for managing patient treatment, and for diagnosing a lysosomal storage disorder in a human subject. | 10-21-2010 |
Frank Y. Hsieh, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090325311 | Measurement methods - The invention relates to methods for measuring unconjugated molecules, e.g. antibodies, in a mixture that also includes conjugated molecules, e.g. antibodies. | 12-31-2009 |
| 20100273989 | ANGIOTENSIN CONVERTING ENZYME HOMOLOG AND USES THEREFOR - The present invention relates to the discovery of novel genes encoding an angiotensin converting enzyme, Angiotensin Converting Enzyme-2 (ACE-2). The invention provides therapeutics, prognostic and diagnostic methods for treating blood pressure related disorders as well as various types of allergic conditions, among others. Also disclosed are screening assays for identifying compounds for treating and preventing these conditions. | 10-28-2010 |
Jennifer Hsieh, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100218105 | Method of browsing and a computer program therefor - A method of browsing a website from the Internet comprises receiving code and/or object from the website from the Internet by a first computer. The code and/or object of the website is transmitted by the first computer to a server computer. The first computer displays the code and/or object of the website at the first computer. The code and/or object of the website received by the server computer is transmitted to a second computer. The code and/or object of the website received by the second computer is displayed at the second computer. The display of the website at the first computer is substantially the same as the display of the website at the second computer. | 08-26-2010 |
Pei-Chung Hsieh, Topsfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090305342 | Solubilization and Purification of a Target Protein fused to a Mutant Maltose-Binding Protein - Methods and compositions are provided for increasing at least one of: (i) binding affinity of a target protein for a maltodextrin substrate and/or (ii) solubility of a target protein. The methods and compositions relate to a modified maltose-binding protein. | 12-10-2009 |
| 20110020911 | SOLUBILIZATION AND PURIFICATION OF A TARGET PROTEIN FUSED TO A MUTANT MALTOSE-BINDING PROTEIN - Methods and compositions are provided for increasing at least one of: (i) binding affinity of a target protein for a maltodextrin substrate and/or (ii) solubility of a target protein. The methods and compositions relate to a modified maltose-binding protein. | 01-27-2011 |
| 20110189753 | Intracellular Production of a Nuclease - Methods and compositions are provided that relate to obtaining a recombinant DNA and RNA cleaving nuclease. This involves the over-expression of a fusion protein between maltose-binding protein and a truncated nuclease in a soluble form in the cytoplasm of a host cell from which it can be readily extracted. | 08-04-2011 |
| 20110256593 | Generation of Random Double-Strand Breaks in DNA Using Enzymes - An enzyme preparation is described that includes a non-specific nuclease and a T7 Endo I mutant in a unit ratio of less than 1:200. This enzyme preparation may be used to generate double-stranded DNA fragments of a size suitable for DNA sequencing. The ends of the fragments can be readily modified as necessary to ligate adaptors or individual nucleotides to one strand of the double-stranded DNA fragments. | 10-20-2011 |
Tseh-Jen Hsieh, Rowley, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120118232 | Hydrogen COGas For Carbon Implant - A system, apparatus and method for increasing ion source lifetime in an ion implanter are provided. Oxidation of the ion source and ion source chamber poisoning resulting from a carbon and oxygen-containing source gas is controlled by utilizing a hydrogen co-gas, which reacts with free oxygen atoms to form hydroxide and water. | 05-17-2012 |
| 20120119113 | Implementation of CO-Gases for Germanium and Boron Ion Implants - An ion implantation system for improving performance and extending lifetime of an ion source is disclosed. A fluorine-containing dopant gas source is introduced into the ion chamber along with one or more co-gases. The one or more co-gases can include hydrogen or krypton. The co-gases mitigate the effects caused by free fluorine ions in the ion source chamber which lead to ion source failure. | 05-17-2012 |
Ya-Ping Hsieh, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110135835 | METHOD FOR DEPOSITING A CARBON NANOTUBE THIN FILM COATING ON AN ARBITRARY SUBSTRATE DIRECTLY FROM CHEMICAL VAPOR DEPOSITION SYNTHESIS - A method includes generating an aerosol comprising a plurality of catalyst particles from a precursor solution comprising a carbon source and a catalyst, transmitting the plurality of catalyst particles through a reaction zone extending along a temperature profile including at least one temperature sufficient to induce in each of the plurality of catalyst particles growth of a plurality of carbon nanotubes, and positioning at least one substrate along the temperature profile and at least partially outside of the reaction zone at a position to collect a portion of the plurality of carbon nanotubes on a surface of the at least one substrate. | 06-09-2011 |