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Hsia, US

Albert Y. Hsia, Cambridge, MA US

Patent application numberDescriptionPublished
20110288081PYRIMIDINE COMPOUNDS AND USES THEREOF - This invention features pyrimidine compounds of formula (I):11-24-2011

Calvin Hsia, Redmond, WA US

Patent application numberDescriptionPublished
20090164935SYMBOL LISTS FOR GRAMMAR-DRIVEN DATA ENTRY - In a data entry environment constrained by a symbolic grammar, a data entry position in the data set may be amenable to the insertion of a subset of symbols in compliance with the grammar. Also, the grammar may or may not permit the insertion of a value of one or more types at the data entry position of the data set. In order to facilitate grammatically correct data entry, a symbol list may be presented that indicates the grammatically valid symbols for the symbolic context of the data entry position, as well as the validity of the insertion of a value at the data entry position. The symbol list may also permit the selection of a symbol list option, and may insert the selected symbol or value at the data entry position. Various symbol list option selection inputs may be associated with the symbol list options to facilitate and economize data entry, and the association may be adapted based on whether or not a value is permitted at the data entry position. Several variations of these techniques are discussed relating to the use of symbol lists in various data entry and grammar scenarios, the presentation of the symbol lists, and the user interaction with the symbol lists.06-25-2009

Constance Y. Hsia, New York, NY US

Patent application numberDescriptionPublished
20100055116Methods and Compositions for Targeting c-Rel - The present invention relates to compositions and methods for targeting c-Rel. In particular, the present invention provides compositions and methods for treating cancers, inflammatory diseases, autoimmune diseases, and transplant rejection by inhibiting c-Rel activity and for regulating c-Rel for research and drug screening applications.03-04-2010

David M. Hsia, Bartlett, IL US

Patent application numberDescriptionPublished
20080319599ENGINE GLOW PLUG DIAGNOSIS USING CRANKSHAFT SENSOR DATA - A motor vehicle engine (12-25-2008
20110041816Apparatus and Method for Protecting Against Fouling of an Exhaust Gas Recirculation Valve - This invention relates to a method for protecting an exhaust gas recirculation (EGR) valve from fouling due to hydrocarbon condensation at low EGR cooler outlet exhaust temperatures. In modern internal combustion engines exhaust gas recirculation (EGR) valves provide a means to recirculate exhaust gases into the intake air stream. The EGR valve regulates the flow of exhaust gas entering the stream. The EGR valve can experience fouling due to the condensation of hydrocarbons at low EGR cooler outlet exhaust temperatures. Typically, fouling occurs when the internal combustion engine is operating at relatively low temperatures, namely during low speed and/or low torque operations. The effects of fouling an EGR valve include higher emission levels, reduction in fuel economy, and rough idling.02-24-2011
20110048389EMG Temp Signal Model Based On EGRC Out Temp For EGR System Anti-Fouling Protection - An EGR control method to prevent condensation within the EGR system uses a temperature sensor signal from an EGR cooler exhaust gas outlet to model or estimate exhaust manifold gas temperature upstream of the cooler. If the estimated exhaust manifold gas temperature falls below a predetermined level, the engine control system closes or partially closes the EGR control valve to stop EGR flow through the cooler and the EGR valve.03-03-2011

James C. Hsia, Weston, MA US

Patent application numberDescriptionPublished
20080215040VARIABLE DEPTH SKIN HEATING WITH LASERS - Treating biological tissue can include selecting parameter for electromagnetic radiation based on at least one parameter of a target region within the biological tissue. Treating biological tissue also includes methods, systems, and kits for delivering the electromagnetic radiation through a surface of the biological tissue to the target region to induce within the target region a sub-surface thermal injury characterized, for example, by a desired degree and a desired depth and confining the sub-surface thermal injury to substantially within the target region.09-04-2008
20080221649Method of sequentially treating tissue - A treatment for deep tissue using long effective pulse durations is described. Fatty tissue can be treated by delivering a beam of radiation to a subcutaneous fat region disposed relative to a dermal interface in a target region of skin. Radiation is delivered to a first region of tissue as by exposure to pulses of the beam of radiation in a stacked fashion. Between successive exposures of the first region of tissue, other regions of tissue are exposed to the beam of radiation.09-11-2008
20080269733METHOD AND APPARATUS FOR TREATING WRINKLES IN SKIN USING RADIATION - A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.10-30-2008
20080269734Optical Array for Treating Biological Tissue - Skin can be treated by penetrating an epidermis of the skin with a plurality of waveguides. Each waveguide has an end, which is positioned within a dermis of the skin. Electromagnetic radiation can be delivered through the plurality of waveguides to the dermis having a port wine stain for a time sufficient to selectively destroy a cutaneous blood vessel within the port wine stain. The time is less than a thermal diffusion time between the epidermis and the dermis to prevent forming substantial unwanted thermal injury within the epidermis.10-30-2008
20080269735Optical array for treating biological tissue - An apparatus can treat biological tissue using a base member, a plurality of needles, and a plurality of fiber optics. The plurality of needles extend from the base member. Each needle defines a bore capable of receiving a fiber optic and has an end. The plurality of needles form an array capable of penetrating a biological tissue and positioning each end within a subsurface volume of the biological tissue. Each fiber optic is adapted for insertion into the bore of each needle, and each fiber optic is capable of delivering electromagnetic radiation to the subsurface volume of the biological tissue to treat the biological tissue.10-30-2008
20110015549METHOD AND APPARATUS FOR TREATING A DISEASED NAIL - A diseased nail is treated using electromagnetic radiation and/or other forms of energy that are applied to the diseased area to eliminate, substantially eliminate or effectively reduce the source of disease in the nail. A sensor can be used to ensure proper placement of an applicator that applies the energy to the diseased area of the nail. A temperature monitor can be employed to monitor changes or temperature levels and then adjust the energy application accordingly. In additional, manual forms of adjustment can be used to control the application of energy.01-20-2011

Patent applications by James C. Hsia, Weston, MA US

Ming Min Hsia, Loudonville, NY US

Patent application numberDescriptionPublished
20110312995BRIDGED AND FUSED HETEROCYCLIC ANTIDIABETIC COMPOUNDS - This invention provides for certain bridged and fused heterocyclic compounds of the formula (I) or a pharmaceutically acceptable salt, ester solvate or prodrug thereof wherein: L is: (II) and the other variables are defined herein; the inventive compounds are agonists of the G-protein coupled receptor 40 (GPR40, also known as free fatty acid receptor FFAR). This invention further relates to pharmaceutical compositions containing these compounds, and the use of these compounds to regulate insulin levels in a mammal. The compounds may be used, for example in the prevention and treatment of Type 2 diabetes mellitus and in the prevention and treatment of conditions related to Type 2 diabetes mellitus, such as insulin resistance, obesity and lipid disorders.12-22-2011
20110313008PENTAFLUOROSULPHOLANE-CONTAINING ANTIDIABETIC COMPOUNDS - This invention provides for certain pentafluorosulpholane-containing compounds of the formula or a pharmaceutically acceptable salt, ester, solvate or prodrug thereof, wherein the variables are defined herein; the inventive compounds are agonists of the G-protein coupled receptor 40 (GPR40, also known as free fatty acid receptor FFAR). This invention further relates to pharmaceutical compositions containing these compounds, and the use of these compounds to regulate insulin levels in a mammal. The compounds may be used, for example in the prevention and treatment of Type 2 diabetes mellitus and in the prevention and treatment of conditions related to Type 2 diabetes mellitus, such as insulin resistance, obesity and lipid disorders.12-22-2011

Mishelle C. Hsia, Piscataway, NJ US

Patent application numberDescriptionPublished
20110155757PACKAGES AND INSERTS THEREOF WITH GUIDE WALL FOR DISPENSING MEDICINAL UNITS - The present invention provides packages for holding medicinal units and dispensing a single medicinal unit at one 06-30-2011

Sung Lan Hsia, Miami, FL US

Patent application numberDescriptionPublished
20080299100Topical Co-Enzyme Q10 Formulations and Methods of Use - Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.12-04-2008
20100062048TOPICAL CO-ENZYME Q10 FORMULATIONS AND TREATMENT OF PAIN, FATIGUE AND WOUNDS - CoQ1O has a stimulatory effect on fibroblasts and keratinocytes, increases ATP production, decreases pain. The formulations are useful for promoting acute wound healing, fatigue and treatment of acute and chronic pain.03-11-2010

Ta-Chung Hsia, Chesterfield, MO US

Patent application numberDescriptionPublished
20110295292VIBRATION DAMPENING OPHTHALMIC PNEUMATIC SURGICAL INSTRUMENT - An ophthalmic pneumatic surgical instrument 12-01-2011

Yiao-Tee Hsia, Sewickley, PA US

Patent application numberDescriptionPublished
20090208171Waveguide For Heat Assisted Magnetic Recording - An apparatus includes a slider mounted on an arm, a first waveguide including a first core guiding layer, a second waveguide mounted on the slider and including a second core guiding layer having a thickness smaller than the thickness of the first core guiding layer, and a coupler for coupling light from the first core guiding layer to the second core guiding layer.08-20-2009

Yiao-Tee Hsia, Wexford, PA US

Patent application numberDescriptionPublished
20090245078LUBRICANT FOR DATA SENSING INTERFACE AND METHOD OF LUBRICATION - A data sensing interface comprising a surface of a recording medium and a tip of a data sensor positioned to sense data stored on the recording medium and a layer of polyphenyl ether disposed between the tip and the surface to function as a lubricant. A method of reducing wear within the data sensing interface includes providing a layer of polyphenyl ether between the tip of the data sensor and the surface of the recording medium to act as a lubricant.10-01-2009
20090263592PLASMA-ENHANCED CHEMICAL VAPOR DEPOSITION OF ADVANCED LUBRICANT FOR THIN FILM STORAGE MEDIUM - A magnetic recording medium including a solid lubricant film containing a plasma-enhanced chemical vapor deposited perfluoropolyether is disclosed. Preferably, the solid lubricant is formed in the presence of oxygen and longer fluorocarbon chain to form perfluoropolyether, thereby enhancing the chain flexibility perfluoropolyether and in the presence of a hydrocarbon to stabilize the process, thereby allowing process control.10-22-2009

Patent applications by Yiao-Tee Hsia, Wexford, PA US