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Hruza

Alan W. Hruza, Hackettstown, NJ US

Patent application numberDescriptionPublished
20090118284Novel compounds that are ERK inhibitors - Disclosed are the ERK inhibitors of formula 1.0:05-07-2009

Patent applications by Alan W. Hruza, Hackettstown, NJ US

Alan William Hruza, Hackettstown, NJ US

Patent application numberDescriptionPublished
20090081706CRYSTALLINE FORM OF THE CATALYTIC DOMAIN OF AURORA 2 KINASE AND METHODS OF USE THEREOF - The present invention discloses nucleic acids that encode an active human Aurora 2 kinase catalytic domain. The present invention also discloses methods of growing X-ray diffractable crystals of polypeptides comprising the active human Aurora 2 kinase catalytic domain. The present invention further discloses a crystalline form of a catalytic domain of human Aurora 2 kinase. In addition, the present invention discloses methods of using the X-ray diffractable crystals of human Aurora 2 kinase in structure assisted drug design to identify compounds that can modulate the enzymatic activity of human Aurora 2 kinase.03-26-2009
20100190231METHODS FOR CRYSTALLIZING ERK2 POLYPEPTIDES - The present invention relates to crystals of the ERK2 polypeptide and complexes thereof which are useful, inter alia, for structure assisted drug design.07-29-2010

Patent applications by Alan William Hruza, Hackettstown, NJ US

Eric Hruza, Plymouth, MN US

Patent application numberDescriptionPublished
20090161895SOUND PROVIDER ADAPTED TO CANCEL OUT NOISE - A sound provider for providing sound to a person's ear includes one or more terminals for receiving a first electrical signal and a first sound emitter operatively connected to the one or more terminals for outputting a sound corresponding to the first electrical signal. The sound provider also includes a sound receiver for receiving sound and outputting a corresponding, second, electrical signal, and a second sound emitter operatively connected to the sound receiver for outputting a sound corresponding to the second electrical signal.06-25-2009

Eric A. Hruza, Plymouth, MN US

Patent application numberDescriptionPublished
20090060245Balanced armature with acoustic low pass filter - A balanced armature apparatus is disclosed that includes dual transducers for generating sound waves in response to electric audio signals. The dual transducers include a motor assembly coupled to a diaphragm. A housing defines an interior chamber and the motor assembly and the diaphragm are positioned within the interior chamber. A pair of acoustic output ports is located in a respective end of the housing. A low pass acoustic filter is in communication with one of the acoustic output ports that is operable to attenuate a predetermined range of frequencies from an audio signal produced by one of the diaphragms.03-05-2009

Sandra L. Hruza, Porter, TX US

Patent application numberDescriptionPublished
20120012526ACCELERATED BIOREMEDIATION USING SUPPLEMENTAL COMPOSITIONS AND OXYGENATED WATER - A method for bioremediation of contaminants, comprising contacting a contaminant with composite particles including at least one microbial available nutrient species and at least one fatty acid species, and contacting the contaminant with oxygenated water including greater than about 4 parts per million dissolved oxygen. Water may be oxygenated on-site using various oxygenating devices, such as an aspirator, aerator, impeller and diffuser. Optionally, the oxygenated water may be prepared with wastewater that is being remediated. The method may be used to maintain a dissolved oxygen concentration of greater than a setpoint concentration, such as at least 4 ppm. A preferred oxygenated water stream or source has a dissolved oxygen concentration of greater than 50 ppm. Where the contaminant is in a wastewater, the dissolved oxygen concentration in the remediation zone or the oxygenated water stream may be measured with a dissolved oxygen sensor.01-19-2012