Patent application number | Description | Published |
20090111704 | PANEL FOR THE DETECTION AND DIFFERENTIATION OF RENAL CORTICAL NEOPLASMS - The present invention provides a novel, highly sensitive and specific probe panel which detects the type of renal cortical neoplasm present in a biopsy sample. As such, the invention permits diagnosis of the predominant subtypes of renal cortical neoplasms without the use of invasive methods. The present invention further provides a molecular cytogenetic method for detecting and analyzing the type of renal cortical neoplasm present in a renal biopsy sample. | 04-30-2009 |
20110160079 | TOOL FOR DIAGNOSIS AND PROGNOSIS OF MATURE B-CELL NEOPLASMS - The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray can include a plurality of genomic regions represented thereon, the genomic regions corresponding to regions wherein alterations, such as copy number alterations, at such locations correlate to specific, identifiable cancers, particularly mature B-cell neoplasms. The invention further provides methods of diagnosing and providing prognosis certain types of cancer, particularly mature B-cell neoplasms. The methods can comprise contacting a sample to a microarray according to the invention, allowing any genetic material in the sample to hybridize to the genomic regions on the microarray, analyzing the hybridizations, and correlating the hybridizations to certain cancer types, particularly mature B-cell neoplasms. | 06-30-2011 |
20120202200 | METHODS FOR DETECTING HUMAN PAPILLOMA VIRUS-ASSOCIATED CANCERS - The present invention provides probes and methods of use thereof in the diagnosis and/or prognosis of certain types of cancers, particularly human papillomavirus (HPV)-associated cancers. The probes are designed for hybridization with genomic material in a manner indicative of one or more aberrations in the genetic material present in the test sample. The identified aberrations are biomarkers of HPV-associated cancer. The methods of the invention comprise contacting a sample to one or more probes, allowing any genetic material in the sample to hybridize to the genomic regions provided in the probes, analyzing the hybridizations, and analyzing the hybridizations to identify detected aberrations as biomarkers indicative of HPV-associated cancer progression. | 08-09-2012 |
20120225430 | METHODS FOR DETECTING HUMAN PAPILLOMA VIRUS-ASSOCIATED CANCERS - The present invention provides probes and methods of use thereof in the diagnosis and/or prognosis of certain types of cancers, particularly human papillomavirus (HPV)-associated cancers. The probes are designed for hybridization with genomic material in a manner indicative of one or more aberrations in the genetic material present in the test sample. The identified aberrations are biomarkers of HPV-associated cancer. The methods of the invention comprise contacting a sample to one or more probes, allowing any genetic material in the sample to hybridize to the genomic regions provided in the probes, analyzing the hybridizations, and analyzing the hybridizations to identify detected aberrations as biomarkers indicative of HPV-associated cancer progression. | 09-06-2012 |
20120225796 | TOOL FOR DIAGNOSIS AND PROGNOSIS OF MATURE B-CELL NEOPLASMS - The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray can include a plurality of genomic regions represented thereon, the genomic regions corresponding to regions wherein alterations, such as copy number alterations, at such locations correlate to specific, identifiable cancers, particularly mature B-cell neoplasms. The invention further provides methods of diagnosing and providing prognosis certain types of cancer, particularly mature B-cell neoplasms. The methods can comprise contacting a sample to a microarray according to the invention, allowing any genetic material in the sample to hybridize to the genomic regions on the microarray, analyzing the hybridizations, and correlating the hybridizations to certain cancer types, particularly mature B-cell neoplasms. | 09-06-2012 |
20130130925 | TOOL FOR DIAGNOSIS AND PROGNOSIS OF MATURE B-CELL NEOPLASMS - The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray can include a plurality of genomic regions represented thereon, the genomic regions corresponding to regions wherein alterations, such as copy number alterations, at such locations correlate to specific, identifiable cancers, particularly mature B-cell neoplasms. The invention further provides methods of diagnosing and providing prognosis certain types of cancer, particularly mature B-cell neoplasms. The methods can comprise contacting a sample to a microarray according to the invention, allowing any genetic material in the sample to hybridize to the genomic regions on the microarray, analyzing the hybridizations, and correlating the hybridizations to certain cancer types, particularly mature B-cell neoplasms. | 05-23-2013 |
20140099639 | PANEL FOR THE DETECTION AND DIFFERENTIATION OF RENAL CORTICAL NEOPLASMS - The present invention provides a novel, highly sensitive and specific probe panel which detects the type of renal cortical neoplasm present in a biopsy sample. As such, the invention permits diagnosis of the predominant subtypes of renal cortical neoplasms without the use of invasive methods. The present invention further provides a molecular cytogenetic method for detecting and analyzing the type of renal cortical neoplasm present in a renal biopsy sample. | 04-10-2014 |
20150031017 | METHODS FOR DETECTING HUMAN PAPILLOMAVIRUS-ASSOCATED CANCERS - The present invention provides probes and methods of use thereof in the diagnosis and/or prognosis of certain types of cancers, particularly human papillomavirus (HPV)-associated cancers. The probes are designed for hybridization with genomic material in a manner indicative of one or more aberrations in the genetic material present in the test sample. The identified aberrations are biomarkers of HPV-associated cancer. The methods of the invention comprise contacting a sample to one or more probes, allowing any genetic material in the sample to hybridize to the genomic regions provided in the probes, analyzing the hybridizations, and analyzing the hybridizations to identify detected aberrations as biomarkers indicative of HPV-associated cancer progression. | 01-29-2015 |
Patent application number | Description | Published |
20100010769 | CELL BASED TEMPERATURE MONITORING - A system and method for measuring a temperature in at least one energy storage unit. The system includes at least one temperature sensor thermally coupled to the at least one energy storage unit, and a battery management controller in communication with the at least one temperature sensor. The battery management controller is configured to process a temperature of the at least one energy storage unit to obtain an internal temperature in the at least one energy storage unit. | 01-14-2010 |
20100109610 | METHOD AND APPARATUS FOR MANAGING ENERGY IN PLURAL ENERGY STORAGE UNITS - A system for managing energy stored in a plurality of series connected energy storage units has a plurality of energy storage unit controllers, each controller being associated with one of the plurality of energy storage units, a balancing circuit between two of the energy storage units, the balancing circuit being controlled by at least one of the energy storage unit controllers, a serial electrical interface between the energy storage unit controllers for providing voltage isolated bi-directional communication, and a central controller in electrical communication with the energy storage unit controllers. A method for managing charge in a plurality of series connected energy storage units forming an energy storage device includes monitoring a current supplied to the energy storage device, determining at least one of a charging rate and a capacity of a first energy storage unit and a second energy storage unit in the energy storage device, and diverting current from the first energy storage unit to the second energy storage unit in response to the steps of monitoring and determining. | 05-06-2010 |
20110031944 | HIGH VOLTAGE LATCHING AND DC RESTORATION ISOLATION AND LEVEL SHIFTING METHOD AND APPARATUS - A device and method for dc isolation and level shifting includes a driver circuit powered by a first voltage range, a capacitor connected to the driver circuit, and a latching circuit connected to the capacitor. The latching circuit is powered by a second voltage range and is configured to restore and/or minimize charge loss of the capacitor during a voltage transition at the capacitor. A device and method for analog isolation and measurement configured to measure an analog voltage at a second potential without requiring analog circuits at the second potential. | 02-10-2011 |
20120056624 | VOLTAGE MONITORING USING BITSTREAM SIGNAL PROCESSING - Systems and methods are provided for monitoring a voltage. A level shifter is configured to generate a current proportional to the voltage of the battery cell. A delta-sigma modulator is configured to convert the current into a first density modulated bitstream representing the voltage of the battery cell. A first reference source is configured to provide a second density modulated bitstream representing a first threshold voltage. A first comparator is configured to compare the first density modulated bitstream and the second density modulated bitstream. | 03-08-2012 |
20120177954 | METHOD AND APPARATUS FOR MANAGING ENERGY IN PLURAL ENERGY STORAGE UNITS - A system for managing energy stored in a plurality of series connected energy storage units has a plurality of energy storage unit controllers, each associated with one of the plurality of energy storage units, a balancing circuit between two of the energy storage units, being controlled by at least one of the energy storage unit controllers, a serial electrical interface between the energy storage unit controllers providing voltage isolated bi-directional communication, and a central controller in electrical communication with the energy storage unit controllers. A method for managing charge in a plurality of series connected energy storage units in which current is diverted from the first energy storage unit to the second energy storage unit. | 07-12-2012 |
20120256656 | HIGH VOLTAGE LATCHING AND DC RESTORATION ISOLATION AND LEVEL SHIFTING METHOD AND APPARATUS - A device and method for dc isolation and level shifting includes a driver circuit powered by a first voltage range, a capacitor connected to the driver circuit, and a latching circuit connected to the capacitor. The latching circuit is powered by a second voltage range and is configured to restore and/or minimize charge loss of the capacitor during a voltage transition at the capacitor. A device and method for analog isolation and measurement configured to measure an analog voltage at a second potential without requiring analog circuits at the second potential. | 10-11-2012 |
20130332103 | CELL BASED TEMPERATURE MONITORING - A system and method for measuring a temperature in at least one energy storage unit. They system includes at least one temperature sensor thermally coupled to the at least one energy storage unit, and a battery management controller in communication with the at least one temperature sensor. The battery management controller is configured to process a temperature of the at least one energy storage unit to obtain an internal temperature in the at least one energy storage unit. | 12-12-2013 |