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Hosheng Tu, Newport Coast US

Hosheng Tu, Newport Coast, CA US

Patent application numberDescriptionPublished
20080200860SYSTEM FOR TREATING OCULAR DISORDERS AND METHODS THEREOF - Systems and methods for treating ocular disorders are disclosed. One system has an implant and a delivery device. The implant has inlet and outlet portions, a lumen extending therebetween and communicating with inlet and outlet ports. The implant is sized so that in use aqueous humor flows from an anterior chamber of an eye through the implant and into a uveal scleral outflow path of the eye. The delivery device is configured to advance the implant from within the anterior chamber, with the outlet portion leading the inlet portion, to a location where the outlet and inlet ports respectively communicate with the uveal scleral outflow path and the anterior chamber. One method involves advancing an implant from within the anterior chamber, and draining fluid from therein such that fluid flows into an implant inlet port and out through an implant outlet port and into the uveal scleral outflow path.08-21-2008
20090036819DRUG ELUTING OCULAR IMPLANT WITH ANCHOR AND METHODS THEREOF - Ocular implants, delivery devices and methods for treating ocular disorders are disclosed. One method involves inserting an implant on one side of an eye. The implant has an anchor on a distal end portion and an outlet opening that is disposed proximal of the anchor. The implant is advanced across the eye to the other side of the eye. The anchor is inserted into eye tissue on the other side of the eye. A therapeutic agent is eluted using the implant.02-05-2009
20090076436OCULAR IMPLANTS WITH DEPLOYABLE STRUCTURE - An implant has a tubular member with an inlet configured to receive fluid from an anterior chamber of an eye, an outlet configured to deliver fluid from the inlet to a physiological outflow pathway of the eye, and a lumen therebetween configured for substantially free flow of the fluid and which generally defines a flow axis. At the outlet of the tubular member is a distal deployable portion that has a compacted position and an expanded position. The deployable portion is configured to expand in the physiological outflow pathway of the eye and moves transversely when transitioning between the compacted and expanded positions about a pivot axis which is substantially perpendicular to the flow axis. 03-19-2009
20090138022OCULAR IMPLANT DELIVERY SYSTEM AND METHOD THEREOF - Systems and methods for treating ocular disorders are disclosed. One system has a delivery instrument, with a non-linear axis, configured to be inserted into an anterior chamber of an eye and moved to a location proximate a physiologic outflow pathway of the eye. The delivery instrument carries an implant that has a distal end sized for insertion into tissue such that aqueous humor drains from the anterior chamber to the physiologic outflow pathway. One method involves inserting a non-linear portion of a delivery device into the anterior chamber to position an implant within the eye. Another method involves using a delivery device with a curved distal portion to implant an implant at a location communicating with the physiologic outflow pathway. The delivery can be through a corneal incision and the implant can comprise a drug.05-28-2009
20090143712SELF-TREPHINING IMPLANT AND METHODS THEREOF FOR TREATMENT OF OCULAR DISORDERS - Implants and methods for treating ocular disorders are disclosed. One implant has a tubular member, with inlet and outlet ends, and a cutting member connected thereto. The tubular member is configured to extend through eye tissue such that the inlet and outlet ends reside respectively in an anterior chamber and a physiologic outflow pathway of the eye. Desirably, the cutting member is configured to make an incision in the eye tissue for receiving at least a portion of the tubular member. One method involves introducing an implant, with proximal and distal ends, into the anterior chamber and penetrating eye tissue using an implant distal portion. The implant is advanced from the anterior chamber into the penetrated eye tissue to locate the distal and proximal ends respectively in the physiologic outflow pathway and the anterior chamber. Aqueous humor is conducted between the proximal and distal ends.06-04-2009
20100056979IMPLANTABLE OCULAR PUMP TO REDUCE INTRAOCULAR PRESSURE - A trabecular pump is implantable in the eye to reduce intraocular pressure. The pump drains aqueous humor from the anterior chamber into outflow pathways, such as Schlemm's canal. A feedback system includes an intraocular pump and a pressure sensor in communication with the pump, for regulating intraocular pressure.03-04-2010
20100087774OCULAR IMPLANT WITH ANCHORING MECHANISM AND MULTIPLE OUTLETS - Devices and methods for treating ocular disorders are disclosed. One ocular implant, has a substantially straight, rigid, elongate body. The body has a self-trephinating distal portion that narrows toward a distal end, and at least one inlet that communicates with at least one inner lumen that communicates with a plurality of outlets. The lumen has a sufficient length to extend from an anterior chamber of an eye to a physiologic outflow pathway. An anchor member extends from the implant.04-08-2010
20100106073METHOD OF MONITORING INTRAOCULAR PRESSURE AND TREATING AN OCULAR DISORDER - The invention discloses a trabecular stent and methods for treating glaucoma. The stent may incorporate an intraocular pressure sensor comprising a compressible element that is implanted inside an anterior chamber of an eye, wherein at least one external dimension of the element correlates with intraocular pressure. In some embodiments, the sensor may be coupled to the stent. Also disclosed are methods of delivery of the stent and the sensor to the eye.04-29-2010
20100234790OCULAR IMPLANT WITH THERAPEUTIC AGENTS AND METHODS THEREOF - Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye such that at least a distal end of the implant is temporarily in the anterior chamber. The implant is implanted into eye tissue adjacent the anterior chamber. A therapeutic agent is eluted from the implant into at least one of the anterior chamber, a physiologic outflow pathway of the eye, and a space adjacent a choroid of the eye. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension. The therapeutic agent can be contained within the implant or coated on the implant.09-16-2010
20110092878OCULAR IMPLANT DELIVERY SYSTEM AND METHODS THEREOF - Systems and methods for treating ocular disorders are disclosed. One system has a delivery instrument, with a non-linear axis, configured to be inserted into an anterior chamber of an eye and moved to a location proximate a physiologic outflow pathway of the eye. The delivery instrument carries an implant that has a distal end sized for insertion into tissue such that aqueous humor drains from the anterior chamber to the physiologic outflow pathway. One method involves inserting a non-linear portion of a delivery device into the anterior chamber to position an implant within the eye. Another method involves using a delivery device with a curved distal portion to implant an implant at a location communicating with the physiologic outflow pathway. The delivery can be through a corneal incision and the implant can comprise a drug.04-21-2011

Patent applications by Hosheng Tu, Newport Coast, CA US