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Horton, GB
James Horton, Hertfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110275637 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS - The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias. | 11-10-2011 |
| 20110275678 | New Pyridine Derivatives as Leptin Receptor Modulator Mimetics - The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias. | 11-10-2011 |
Jeff Horton, Cardiff GB
| Patent application number | Description | Published |
|---|---|---|
| 20110244487 | METHODS FOR TESTING BINDING OF A LIGAND TO A G PROTEIN-COUPLED RECEPTOR - The present invention relates to methods for testing for the binding of a ligand to a G Protein-Coupled Receptor. In particular, the methods of the invention are useful in high throughput screening for ligands which bind to G Protein-Coupled Receptors. | 10-06-2011 |
Jeffrey Horton, Cardiff GB
| Patent application number | Description | Published |
|---|---|---|
| 20120021440 | METHODS FOR TESTING LIGAND BINDING TO G PROTEIN-COUPLED RECEPTORS - The present invention relates to methods for testing for the binding of a ligand to a G Protein-Coupled Receptor. In particular, the methods of the invention are useful in high throughput screening for ligands which bind to G Protein-Coupled Receptors. | 01-26-2012 |
Jeffrey K. Horton, Cardiff GB
| Patent application number | Description | Published |
|---|---|---|
| 20100311069 | MULTIPLEX CELL SIGNALLING ASSAYS - Disclosed are methods useful in multiplex cell-based assays for compound screening employing imaging instrumentation. The methods described herein offer high content information relating to the biological potency of test agents, off-target effects and cellular toxicity of potential drug candidates. | 12-09-2010 |
Jeffrey Kenneth Horton, Cardiff GB
| Patent application number | Description | Published |
|---|---|---|
| 20120101005 | METHODS FOR PREDICTING THE TOXICITY OF A CHEMICAL - The invention relates to methods and kits for predicting the effect of a chemical on a developmental pathway. In particular, the invention relates to methods and kits for predicting the toxicity of a chemical on human developmental pathways. The methods and kits of the invention can be used for predicting changes in a cellular biomap or a developmental pathway during human foetal development. | 04-26-2012 |
John Horton, Southampton GB
| Patent application number | Description | Published |
|---|---|---|
| 20100076015 | Aminopyridine Derivatives - The present invention provides compounds of formula (I): | 03-25-2010 |
Martin R Horton, Loughborough GB
| Patent application number | Description | Published |
|---|---|---|
| 20090199746 | Table - A table comprising a frame, a table top surface and a folding leg mechanism, wherein said frame includes a perimeter portion that defines the outside edges of said table, the perimeter portion comprising a plurality of elongate sections joined together by at least one connector, said connector including a first joining part adapted to engage a complimentary part on one of the elongate sections and a second joining part adapted to engage a complimentary part on one of the other elongate sections, said connector also including a mount to connect at least part of the folding leg mechanism to said frame. | 08-13-2009 |
Oliver Trevor Horton, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20120085870 | VEHICLE ARMREST - An armrest for use by a pilot whilst operating a side stick inceptor has on its underside a number of secondary controls which can be operated when the side stick is not being used, the armrest then acting as a handgrip enabling the pilot to operate the secondary controls with a steady hand. | 04-12-2012 |
Peter Horton, Sheffield GB
| Patent application number | Description | Published |
|---|---|---|
| 20080318778 | Agriculture Composition Method Comprising Nitric Oxide Generating Agent - The invention discloses the use of a composition comprising at least one nitric oxide generating agent for increasing production of and/or retention of a plant organ. | 12-25-2008 |
Philip Norman Horton, Witney GB
| Patent application number | Description | Published |
|---|---|---|
| 20100294768 | RESEALABLE BEVERAGE CAN ENDS - A can end combination, a resealable beverage can, and a method of sealing a beverage can are disclosed. The can end combination may include a metal can end and a resealable closure coupled to the can end. The can end may include a center panel having an aperture formed therethrough. The closure may include a base plate and a top plate coupled to the base plate. The closure may have a sealed position in which the base plate contacts the center panel about the aperture to form at least one of a bore seal and a face seal. The closure may also have an intermediate position in which the base plate is proximate the aperture but the closure is devoid of the bore seal and the face seal. The closure may also have a fully open position in which the aperture is exposed to enable pouring liquid through the aperture. | 11-25-2010 |
Richard Horton, Stourbridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20090179438 | Rotary Pawl Latch - A latch assembly for releasably securing a first member in a closed position relative to a second member is disclosed. The latch assembly includes a frames a rotary pawl, a locking member, a handle, and a lock plug. The frame is adapted for attachment to the first member. The handle is pivotally attached to the frame and is movable between a closed position and an open position. The locking member retains the pawl in the latched position when the locking member is in an undeflected configuration. The handle causes the locking member to deflect and release the pawl from a latched position when the lacking member is in an unlocked position and the handle is moved to the open position. The lock barrel is supported by the frame and can selectively move the locking member to a locked position where the locking member cannot be actuated by the handle. | 07-16-2009 |
Richard Horton, Belfast GB
| Patent application number | Description | Published |
|---|---|---|
| 20110274741 | INGESTIBLE COMPOSITIONS AND PROCESSES OF PREPARATION - One or more of hydrolysed wheat flour, soluble dietary fibre, prebiotic dietary fibre, polydextrose and soluble corn fibre ate used as basic matrix-forming ingredients in an expanded food product. The matrix-forming ingredients are mixed together with water, plus a whey protein isolate or whey protein concentrate, to increase the protein content of the food. A dough is formed which is then formed into pieces which are temperature conditioned before being expanded under a vacuum caused by evaporation of moisture in the dough. All steps of the process of making the expanded food products, including any subsequent drying, is carried out at a temperature not exceeding 75° C., which advantageously allows mixing in of temperature sensitive ingredients, e.g. vitamins, pharmaceuticals, at the dough forming stage. The products have a honeycomb structure and there is no significant change in flavour or nutritional value of the ingredients caused by the process of manufacture. Advantageously, acrylamide formation is also avoided. | 11-10-2011 |
Steuart Horton, Cleveland GB
| Patent application number | Description | Published |
|---|---|---|
| 20100025939 | Sealing Device and Method of Producing the Same - A sealing device for sealing a first side against a second side of a machine part, wherein the sealing device has a sealing element which contacts a counter element. At least a part of the sealing element and/or at least a part of the counter element is coated with a layer consisting of or containing fullerene-like carbon nitride (FL-CNx), wherein an inter-layer of chromium (Cr) or aluminium (Al) or molybdenum (Mo) or titanium (Ti) or tungsten (W) or a diamond-like coating (DLC) or a metal-mix diamond-like coating (Me-DLC) is arranged between the surface of the sealing element and the layer consisting of or containing fullerene-like carbon nitride and/or between the surface of the counter element and the layer consisting of or containing fullerene-like carbon nitride. | 02-04-2010 |
| 20100034495 | Bearing and method of producing the same - A bearing comprises at least one inner ring and at least one outer ring. At least a part of the surfaces of the inner ring and/or the outer ring is coated with a layer consisting of or containing fullerene-like carbon nitride (FL-CNx), and wherein an inter-layer of chromium (Cr) or aluminium (Al) or molybdenum (Mo) or titanium (Ti) or tungsten (W) or a diamond-like coating (DLC) or a metal-mix diamond-like coating (Me-DLC) is arranged between the surface of the inner ring and/or the outer ring and the layer. | 02-11-2010 |
Thomas J. Horton, Malvern GB
| Patent application number | Description | Published |
|---|---|---|
| 20100250185 | Method for detection of gravitational anomalies - A method and system for detecting gravitational anomalies comprises measuring surface structures, measuring gravitational field characteristics, and estimating the effect of the surface structures on the gravitational measurements. The estimations are then used to derive a representation of nearby non visible features such as changes in rock density, voids, or oil and gas deposits. The surface structures may be measured by a video camera, with the video sequence being processed to estimate 3D positions of structures relative to the measurement point. Other methods may be used, such as lidar or acoustic techniques as appropriate. The method may be applied above ground and also has efficacy in borehole and sewer surveying applications. | 09-30-2010 |
Thomas John Horton, Worcestershire GB
| Patent application number | Description | Published |
|---|---|---|
| 20120032675 | Apparatus and Method for Ferromagnetic Object Detector - An apparatus is provided for compensating for the effect of a stray ferromagnetic object moving past but not through a sensing region of a ferromagnetic object detector. The ferromagnetic object detector is of a type to produce a plurality of sensor signals, each sensor signal being influenced by the presence of a genuine ferromagnetic object moving through the sensing region but also liable to be influenced by the presence of the stray object. The apparatus comprises: an input for receiving the plurality of sensor signals and first means for analysing the received signals to determine whether there is a substantially same time-varying component present in each of the signals. The apparatus also comprises second means for determining whether the plurality of signals without the contribution of that time-varying component are each or collectively below a predetermined level of significance. The apparatus also comprises third means for indicating, if the respective determinations from the first and second means are both positive, that the received signals are likely to relate to a stray object and not to a genuine ferromagnetic object moving through the sensing region. | 02-09-2012 |
| 20120074943 | Apparatus and Method for Ferromagnetic Object Detector - An apparatus is provided for compensating for the effect of a moving door on a nearby ferromagnetic object detector. The ferromagnetic object detector is of a type to produce a main sensor signal indicative of the presence of a ferromagnetic object in the vicinity of the ferromagnetic object detector. Furthermore, the door is arranged relative to the ferromagnetic object detector such that movement of the door is liable to introduce an undesirable interference signal into the main sensor signal. The apparatus comprises an input ( | 03-29-2012 |